Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis.
Identifieur interne : 006A05 ( PubMed/Corpus ); précédent : 006A04; suivant : 006A06Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis.
Auteurs : F. Partono ; Purnomo ; A. Soewarta ; S. OemijatiSource :
- Transactions of the Royal Society of Tropical Medicine and Hygiene [ 0035-9203 ] ; 1984.
English descriptors
- KwdEn :
- Brugia, Child, Community Health Workers, Diethylcarbamazine (administration & dosage), Diethylcarbamazine (therapeutic use), Elephantiasis (prevention & control), Filariasis (prevention & control), Humans, Lymphadenitis (prevention & control), Lymphangitis (prevention & control), Pilot Projects, Wuchereria bancrofti.
- MESH :
- chemical , administration & dosage : Diethylcarbamazine.
- chemical , therapeutic use : Diethylcarbamazine.
- prevention & control : Elephantiasis, Filariasis, Lymphadenitis, Lymphangitis.
- Brugia, Child, Community Health Workers, Humans, Pilot Projects, Wuchereria bancrofti.
Abstract
The results of mass treatment using low dosage diethylcarbamazine (DEC) in three small villages in West Flores, Indonesia, endemic for Brugia timori are described. DEC was distributed on a weekly basis by motivated persons in the community to nearly all villagers for 18 months. An educational programme was developed which focused on describing the relationship between microfilaraemia, vector and disease manifestations, the danger of repeated attacks of adenolymphangitis, and the efficiency of DEC in eliminating the parasites and attacks. During the consolidation phase motivated persons were assigned to treat promptly all cases with acute filariasis and to distribute DEC to all new residents. With this programme the microfilaria rates decreased to very low levels, even as detected by the use of membrane filtration techniques. The adenolymphangitis rates also decreased. An unexpected bonus was the cure of "elephantiasis" in many people. Mild side effects attributed to DEC were encountered only during the first few weeks of treatment.
PubMed: 6380025
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Oemijati</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1984">1984</date><idno type="RBID">pubmed:6380025</idno><idno type="pmid">6380025</idno><idno type="wicri:Area/PubMed/Corpus">006A05</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006A05</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis.</title><author><name sortKey="Partono, F" sort="Partono, F" uniqKey="Partono F" first="F" last="Partono">F. Partono</name></author><author><name sortKey="Purnomo" sort="Purnomo" uniqKey="Purnomo" last="Purnomo">Purnomo</name></author><author><name sortKey="Soewarta, A" sort="Soewarta, A" uniqKey="Soewarta A" first="A" last="Soewarta">A. Soewarta</name></author><author><name sortKey="Oemijati, S" sort="Oemijati, S" uniqKey="Oemijati S" first="S" last="Oemijati">S. Oemijati</name></author></analytic><series><title level="j">Transactions of the Royal Society of Tropical Medicine and Hygiene</title><idno type="ISSN">0035-9203</idno><imprint><date when="1984" type="published">1984</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Brugia</term><term>Child</term><term>Community Health Workers</term><term>Diethylcarbamazine (administration & dosage)</term><term>Diethylcarbamazine (therapeutic use)</term><term>Elephantiasis (prevention & control)</term><term>Filariasis (prevention & control)</term><term>Humans</term><term>Lymphadenitis (prevention & control)</term><term>Lymphangitis (prevention & control)</term><term>Pilot Projects</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Diethylcarbamazine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis</term><term>Filariasis</term><term>Lymphadenitis</term><term>Lymphangitis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Brugia</term><term>Child</term><term>Community Health Workers</term><term>Humans</term><term>Pilot Projects</term><term>Wuchereria bancrofti</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The results of mass treatment using low dosage diethylcarbamazine (DEC) in three small villages in West Flores, Indonesia, endemic for Brugia timori are described. DEC was distributed on a weekly basis by motivated persons in the community to nearly all villagers for 18 months. An educational programme was developed which focused on describing the relationship between microfilaraemia, vector and disease manifestations, the danger of repeated attacks of adenolymphangitis, and the efficiency of DEC in eliminating the parasites and attacks. During the consolidation phase motivated persons were assigned to treat promptly all cases with acute filariasis and to distribute DEC to all new residents. With this programme the microfilaria rates decreased to very low levels, even as detected by the use of membrane filtration techniques. The adenolymphangitis rates also decreased. An unexpected bonus was the cure of "elephantiasis" in many people. Mild side effects attributed to DEC were encountered only during the first few weeks of treatment.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">6380025</PMID><DateCreated><Year>1984</Year><Month>09</Month><Day>14</Day></DateCreated><DateCompleted><Year>1984</Year><Month>09</Month><Day>14</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0035-9203</ISSN><JournalIssue CitedMedium="Print"><Volume>78</Volume><Issue>3</Issue><PubDate><Year>1984</Year></PubDate></JournalIssue><Title>Transactions of the Royal Society of Tropical Medicine and Hygiene</Title><ISOAbbreviation>Trans. R. Soc. Trop. Med. Hyg.</ISOAbbreviation></Journal><ArticleTitle>Low dosage diethylcarbamazine administered by villagers for the control of timorian filariasis.</ArticleTitle><Pagination><MedlinePgn>370-2</MedlinePgn></Pagination><Abstract><AbstractText>The results of mass treatment using low dosage diethylcarbamazine (DEC) in three small villages in West Flores, Indonesia, endemic for Brugia timori are described. DEC was distributed on a weekly basis by motivated persons in the community to nearly all villagers for 18 months. An educational programme was developed which focused on describing the relationship between microfilaraemia, vector and disease manifestations, the danger of repeated attacks of adenolymphangitis, and the efficiency of DEC in eliminating the parasites and attacks. During the consolidation phase motivated persons were assigned to treat promptly all cases with acute filariasis and to distribute DEC to all new residents. With this programme the microfilaria rates decreased to very low levels, even as detected by the use of membrane filtration techniques. The adenolymphangitis rates also decreased. An unexpected bonus was the cure of "elephantiasis" in many people. Mild side effects attributed to DEC were encountered only during the first few weeks of treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Partono</LastName><ForeName>F</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Purnomo</LastName></Author><Author ValidYN="Y"><LastName>Soewarta</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Oemijati</LastName><ForeName>S</ForeName><Initials>S</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Trans R Soc Trop Med Hyg</MedlineTA><NlmUniqueID>7506129</NlmUniqueID><ISSNLinking>0035-9203</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>V867Q8X3ZD</RegistryNumber><NameOfSubstance UI="D004049">Diethylcarbamazine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002009" MajorTopicYN="N">Brugia</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003150" MajorTopicYN="N">Community Health Workers</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004049" MajorTopicYN="N">Diethylcarbamazine</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004604" MajorTopicYN="N">Elephantiasis</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005368" MajorTopicYN="N">Filariasis</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008199" MajorTopicYN="N">Lymphadenitis</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008205" MajorTopicYN="N">Lymphangitis</DescriptorName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010865" MajorTopicYN="N">Pilot Projects</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1984</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1984</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1984</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">6380025</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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