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Postmastectomy angiosarcoma.

Identifieur interne : 006908 ( PubMed/Corpus ); précédent : 006907; suivant : 006909

Postmastectomy angiosarcoma.

Auteurs : M B Martin ; N D Kon ; E H Kawamoto ; R T Myers ; J M Sterchi

Source :

RBID : pubmed:6541442

English descriptors

Abstract

Six cases of postmastectomy angiosarcoma of the upper extremity have been treated at the North Carolina Baptist Hospital/Wake Forest University Medical Center over the past 25 years. Five patients had typical ductal carcinoma; one patient had mammary Paget's disease. Two patients, including the patient with Paget's disease, had bilateral mastectomies. The five patients with ductal carcinoma had received postoperative radiation therapy. The mean interval between mastectomy and the appearance of angiosarcoma was 17.5 years. Significant lymphedema of the upper extremity preceded the appearance of angiosarcoma in all six patients, and it appears important that special care be taken during mastectomy to preserve the integrity of the lymphatic system. The patient treated with interscapulothoracic amputation is alive at 2 years postamputation; the five patients whose angiosarcomas were treated with wide excision or radiotherapy died an average of 4.5 years later. Interscapulothoracic amputation is recommended as the initial treatment of postmastectomy angiosarcoma of the upper extremity.

PubMed: 6541442

Links to Exploration step

pubmed:6541442

Le document en format XML

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<name sortKey="Kon, N D" sort="Kon, N D" uniqKey="Kon N" first="N D" last="Kon">N D Kon</name>
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<name sortKey="Kawamoto, E H" sort="Kawamoto, E H" uniqKey="Kawamoto E" first="E H" last="Kawamoto">E H Kawamoto</name>
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<name sortKey="Myers, R T" sort="Myers, R T" uniqKey="Myers R" first="R T" last="Myers">R T Myers</name>
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<div type="abstract" xml:lang="en">Six cases of postmastectomy angiosarcoma of the upper extremity have been treated at the North Carolina Baptist Hospital/Wake Forest University Medical Center over the past 25 years. Five patients had typical ductal carcinoma; one patient had mammary Paget's disease. Two patients, including the patient with Paget's disease, had bilateral mastectomies. The five patients with ductal carcinoma had received postoperative radiation therapy. The mean interval between mastectomy and the appearance of angiosarcoma was 17.5 years. Significant lymphedema of the upper extremity preceded the appearance of angiosarcoma in all six patients, and it appears important that special care be taken during mastectomy to preserve the integrity of the lymphatic system. The patient treated with interscapulothoracic amputation is alive at 2 years postamputation; the five patients whose angiosarcomas were treated with wide excision or radiotherapy died an average of 4.5 years later. Interscapulothoracic amputation is recommended as the initial treatment of postmastectomy angiosarcoma of the upper extremity.</div>
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