Chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the Philippines.
Identifieur interne : 006512 ( PubMed/Corpus ); précédent : 006511; suivant : 006513Chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the Philippines.
Auteurs : M. Hirai ; K. Omoto ; H. Tanaka ; S. Misawa ; A S Mercado ; I G Pagaran ; W. EviotaSource :
- The Japanese journal of experimental medicine [ 0021-5031 ] ; 1986.
English descriptors
- KwdEn :
- MESH :
- geographic : Philippines.
- genetics : Elephantiasis, Filarial, Lymphedema.
- isolation & purification : Wuchereria bancrofti.
- parasitology : Elephantiasis, Filarial.
- pathology : Elephantiasis, Filarial.
- physiology : Leukocytes.
- African Continental Ancestry Group, Chromosome Aberrations, Humans.
Abstract
In the course of genetic population surveys of a tribal group of the Philippine Negritos living on Mindanao island, microfilariae (Wuchereria bancrofti) were incidentally found on the microscopic slides for a cytogenetic investigation. Structural chromosome aberrations in the cultured leukocytes from 19 filaria-infected and 22 uninfected subjects were studied. The frequencies of chromosome type aberrations such as dicentrics and chromosome breaks in the infected subjects were significantly higher than those in the uninfected subjects (P less than 0.05). The frequencies of chromatid type aberrations, however, were not significantly different between the filaria-infected subjects and the uninfected subjects.
PubMed: 3298746
Links to Exploration step
pubmed:3298746Le document en format XML
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Eviota</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1986">1986</date><idno type="RBID">pubmed:3298746</idno><idno type="pmid">3298746</idno><idno type="wicri:Area/PubMed/Corpus">006512</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006512</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the Philippines.</title><author><name sortKey="Hirai, M" sort="Hirai, M" uniqKey="Hirai M" first="M" last="Hirai">M. Hirai</name></author><author><name sortKey="Omoto, K" sort="Omoto, K" uniqKey="Omoto K" first="K" last="Omoto">K. Omoto</name></author><author><name sortKey="Tanaka, H" sort="Tanaka, H" uniqKey="Tanaka H" first="H" last="Tanaka">H. Tanaka</name></author><author><name sortKey="Misawa, S" sort="Misawa, S" uniqKey="Misawa S" first="S" last="Misawa">S. Misawa</name></author><author><name sortKey="Mercado, A S" sort="Mercado, A S" uniqKey="Mercado A" first="A S" last="Mercado">A S Mercado</name></author><author><name sortKey="Pagaran, I G" sort="Pagaran, I G" uniqKey="Pagaran I" first="I G" last="Pagaran">I G Pagaran</name></author><author><name sortKey="Eviota, W" sort="Eviota, W" uniqKey="Eviota W" first="W" last="Eviota">W. Eviota</name></author></analytic><series><title level="j">The Japanese journal of experimental medicine</title><idno type="ISSN">0021-5031</idno><imprint><date when="1986" type="published">1986</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>African Continental Ancestry Group</term><term>Chromosome Aberrations</term><term>Elephantiasis, Filarial (genetics)</term><term>Elephantiasis, Filarial (parasitology)</term><term>Elephantiasis, Filarial (pathology)</term><term>Humans</term><term>Leukocytes (physiology)</term><term>Lymphedema (genetics)</term><term>Philippines</term><term>Wuchereria bancrofti (isolation & purification)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Philippines</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Leukocytes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>African Continental Ancestry Group</term><term>Chromosome Aberrations</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In the course of genetic population surveys of a tribal group of the Philippine Negritos living on Mindanao island, microfilariae (Wuchereria bancrofti) were incidentally found on the microscopic slides for a cytogenetic investigation. Structural chromosome aberrations in the cultured leukocytes from 19 filaria-infected and 22 uninfected subjects were studied. The frequencies of chromosome type aberrations such as dicentrics and chromosome breaks in the infected subjects were significantly higher than those in the uninfected subjects (P less than 0.05). The frequencies of chromatid type aberrations, however, were not significantly different between the filaria-infected subjects and the uninfected subjects.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3298746</PMID><DateCreated><Year>1987</Year><Month>07</Month><Day>24</Day></DateCreated><DateCompleted><Year>1987</Year><Month>07</Month><Day>24</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0021-5031</ISSN><JournalIssue CitedMedium="Print"><Volume>56</Volume><Issue>6</Issue><PubDate><Year>1986</Year><Month>Dec</Month></PubDate></JournalIssue><Title>The Japanese journal of experimental medicine</Title><ISOAbbreviation>Jpn. J. Exp. Med.</ISOAbbreviation></Journal><ArticleTitle>Chromosome aberrations in leukocytes of filaria-infected indigenous inhabitants in the Philippines.</ArticleTitle><Pagination><MedlinePgn>285-91</MedlinePgn></Pagination><Abstract><AbstractText>In the course of genetic population surveys of a tribal group of the Philippine Negritos living on Mindanao island, microfilariae (Wuchereria bancrofti) were incidentally found on the microscopic slides for a cytogenetic investigation. Structural chromosome aberrations in the cultured leukocytes from 19 filaria-infected and 22 uninfected subjects were studied. The frequencies of chromosome type aberrations such as dicentrics and chromosome breaks in the infected subjects were significantly higher than those in the uninfected subjects (P less than 0.05). The frequencies of chromatid type aberrations, however, were not significantly different between the filaria-infected subjects and the uninfected subjects.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hirai</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Omoto</LastName><ForeName>K</ForeName><Initials>K</Initials></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Misawa</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Mercado</LastName><ForeName>A S</ForeName><Initials>AS</Initials></Author><Author ValidYN="Y"><LastName>Pagaran</LastName><ForeName>I G</ForeName><Initials>IG</Initials></Author><Author ValidYN="Y"><LastName>Eviota</LastName><ForeName>W</ForeName><Initials>W</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Japan</Country><MedlineTA>Jpn J Exp Med</MedlineTA><NlmUniqueID>9800765</NlmUniqueID><ISSNLinking>0021-5031</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D044383" MajorTopicYN="N">African Continental Ancestry Group</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002869" MajorTopicYN="Y">Chromosome Aberrations</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName><QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007962" MajorTopicYN="N">Leukocytes</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010679" MajorTopicYN="N" Type="Geographic">Philippines</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="N">isolation & purification</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1986</Year><Month>12</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1986</Year><Month>12</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1986</Year><Month>12</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3298746</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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