The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.
Identifieur interne : 006185 ( PubMed/Corpus ); précédent : 006184; suivant : 006186The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.
Auteurs : P J Hoskin ; G W HanksSource :
- Journal of the Royal Society of Medicine [ 0141-0768 ] ; 1988.
English descriptors
- KwdEn :
- Acupuncture Therapy, Adult, Aged, Aged, 80 and over, Analgesics (administration & dosage), Analgesics (therapeutic use), Antiemetics (therapeutic use), Cancer Care Facilities, Combined Modality Therapy, Female, Hospital Units, Hospitalization, Hospitals, Special, Humans, Male, Middle Aged, Neoplasms (therapy), Palliative Care, Retrospective Studies, Transcutaneous Electric Nerve Stimulation.
- MESH :
- chemical , administration & dosage : Analgesics.
- chemical , therapeutic use : Analgesics, Antiemetics.
- therapy : Neoplasms.
- Acupuncture Therapy, Adult, Aged, Aged, 80 and over, Cancer Care Facilities, Combined Modality Therapy, Female, Hospital Units, Hospitalization, Hospitals, Special, Humans, Male, Middle Aged, Palliative Care, Retrospective Studies, Transcutaneous Electric Nerve Stimulation.
Abstract
The treatment received by 158 patients with advanced cancer admitted over one year to the Continuing Care Unit at the Royal Marsden Hospital has been reviewed. The unit is an integral part of the hospital and this is reflected in the fact that 46 patients (29%) received radiotherapy, hormone therapy, chemotherapy or surgery in addition to symptomatic treatment for palliation of troublesome symptoms. One hundred and thirty-one patients received oral morphine in doses ranging from 2.5 mg 4-hourly to 700 mg 4-hourly. Patients with renal or hepatic impairment required lower doses of morphine and there was a highly significant inverse relationship between morphine dose and age. Eighty-five patients (54%) received parenteral diamorphine at some time due to their inability to take oral morphine. One hundred and twenty-three patients (78%) received a co-analgesic drug and anti-emetics were required by 78 patients (49% overall; 56% of those receiving morphine). Transcutaneous electrical nerve stimulation, acupuncture and relaxation were employed in selected patients, and graduated compression sleeves were used to treat lymphoedema. These data highlight the wide range of therapeutic options available to control the symptoms of advanced cancer and also indicate that tumoricidal treatments used in conjunction with symptomatic treatments may have a significant part to play.
DOI: 10.1177/014107688808100615
PubMed: 2457110
Links to Exploration step
pubmed:2457110Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.</title><author><name sortKey="Hoskin, P J" sort="Hoskin, P J" uniqKey="Hoskin P" first="P J" last="Hoskin">P J Hoskin</name><affiliation><nlm:affiliation>Continuing Care Unit, Royal Marsden Hospital, Sutton, Surrey.</nlm:affiliation></affiliation></author><author><name sortKey="Hanks, G W" sort="Hanks, G W" uniqKey="Hanks G" first="G W" last="Hanks">G W Hanks</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1988">1988</date><idno type="RBID">pubmed:2457110</idno><idno type="pmid">2457110</idno><idno type="doi">10.1177/014107688808100615</idno><idno type="wicri:Area/PubMed/Corpus">006185</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006185</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.</title><author><name sortKey="Hoskin, P J" sort="Hoskin, P J" uniqKey="Hoskin P" first="P J" last="Hoskin">P J Hoskin</name><affiliation><nlm:affiliation>Continuing Care Unit, Royal Marsden Hospital, Sutton, Surrey.</nlm:affiliation></affiliation></author><author><name sortKey="Hanks, G W" sort="Hanks, G W" uniqKey="Hanks G" first="G W" last="Hanks">G W Hanks</name></author></analytic><series><title level="j">Journal of the Royal Society of Medicine</title><idno type="ISSN">0141-0768</idno><imprint><date when="1988" type="published">1988</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acupuncture Therapy</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Analgesics (administration & dosage)</term><term>Analgesics (therapeutic use)</term><term>Antiemetics (therapeutic use)</term><term>Cancer Care Facilities</term><term>Combined Modality Therapy</term><term>Female</term><term>Hospital Units</term><term>Hospitalization</term><term>Hospitals, Special</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neoplasms (therapy)</term><term>Palliative Care</term><term>Retrospective Studies</term><term>Transcutaneous Electric Nerve Stimulation</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Analgesics</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Analgesics</term><term>Antiemetics</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Acupuncture Therapy</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cancer Care Facilities</term><term>Combined Modality Therapy</term><term>Female</term><term>Hospital Units</term><term>Hospitalization</term><term>Hospitals, Special</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Palliative Care</term><term>Retrospective Studies</term><term>Transcutaneous Electric Nerve Stimulation</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The treatment received by 158 patients with advanced cancer admitted over one year to the Continuing Care Unit at the Royal Marsden Hospital has been reviewed. The unit is an integral part of the hospital and this is reflected in the fact that 46 patients (29%) received radiotherapy, hormone therapy, chemotherapy or surgery in addition to symptomatic treatment for palliation of troublesome symptoms. One hundred and thirty-one patients received oral morphine in doses ranging from 2.5 mg 4-hourly to 700 mg 4-hourly. Patients with renal or hepatic impairment required lower doses of morphine and there was a highly significant inverse relationship between morphine dose and age. Eighty-five patients (54%) received parenteral diamorphine at some time due to their inability to take oral morphine. One hundred and twenty-three patients (78%) received a co-analgesic drug and anti-emetics were required by 78 patients (49% overall; 56% of those receiving morphine). Transcutaneous electrical nerve stimulation, acupuncture and relaxation were employed in selected patients, and graduated compression sleeves were used to treat lymphoedema. These data highlight the wide range of therapeutic options available to control the symptoms of advanced cancer and also indicate that tumoricidal treatments used in conjunction with symptomatic treatments may have a significant part to play.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2457110</PMID><DateCreated><Year>1988</Year><Month>09</Month><Day>21</Day></DateCreated><DateCompleted><Year>1988</Year><Month>09</Month><Day>21</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0141-0768</ISSN><JournalIssue CitedMedium="Print"><Volume>81</Volume><Issue>6</Issue><PubDate><Year>1988</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Journal of the Royal Society of Medicine</Title><ISOAbbreviation>J R Soc Med</ISOAbbreviation></Journal><ArticleTitle>The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.</ArticleTitle><Pagination><MedlinePgn>341-4</MedlinePgn></Pagination><Abstract><AbstractText>The treatment received by 158 patients with advanced cancer admitted over one year to the Continuing Care Unit at the Royal Marsden Hospital has been reviewed. The unit is an integral part of the hospital and this is reflected in the fact that 46 patients (29%) received radiotherapy, hormone therapy, chemotherapy or surgery in addition to symptomatic treatment for palliation of troublesome symptoms. One hundred and thirty-one patients received oral morphine in doses ranging from 2.5 mg 4-hourly to 700 mg 4-hourly. Patients with renal or hepatic impairment required lower doses of morphine and there was a highly significant inverse relationship between morphine dose and age. Eighty-five patients (54%) received parenteral diamorphine at some time due to their inability to take oral morphine. One hundred and twenty-three patients (78%) received a co-analgesic drug and anti-emetics were required by 78 patients (49% overall; 56% of those receiving morphine). Transcutaneous electrical nerve stimulation, acupuncture and relaxation were employed in selected patients, and graduated compression sleeves were used to treat lymphoedema. These data highlight the wide range of therapeutic options available to control the symptoms of advanced cancer and also indicate that tumoricidal treatments used in conjunction with symptomatic treatments may have a significant part to play.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hoskin</LastName><ForeName>P J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Continuing Care Unit, Royal Marsden Hospital, Sutton, Surrey.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hanks</LastName><ForeName>G W</ForeName><Initials>GW</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J R Soc Med</MedlineTA><NlmUniqueID>7802879</NlmUniqueID><ISSNLinking>0141-0768</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000700">Analgesics</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000932">Antiemetics</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Clin Pharmacol Ther. 1980 Dec;28(6):823-6</RefSource><PMID Version="1">7438698</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1982 May 1;1(8279):1018</RefSource><PMID Version="1">6122829</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1982 Jun 19;1(8286):1410</RefSource><PMID Version="1">6123696</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J R Coll Physicians Lond. 1986 Oct;20(4):276-81</RefSource><PMID Version="1">2877091</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br Med J (Clin Res Ed). 1984 Mar 17;288(6420):860</RefSource><PMID Version="1">6423114</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J R Coll Physicians Lond. 1984 Jan;18(1):32-9</RefSource><PMID Version="1">6368810</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1984 Jun 30;1(8392):1477-8</RefSource><PMID Version="1">6145924</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Pharmacol Ther. 1983 Sep;34(3):364-8</RefSource><PMID Version="1">6883911</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D015670" MajorTopicYN="N">Acupuncture Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000700" MajorTopicYN="N">Analgesics</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000932" MajorTopicYN="N">Antiemetics</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002173" MajorTopicYN="Y">Cancer Care Facilities</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003131" MajorTopicYN="N">Combined Modality Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006757" MajorTopicYN="Y">Hospital Units</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="Y">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006782" MajorTopicYN="Y">Hospitals, Special</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009369" MajorTopicYN="N">Neoplasms</DescriptorName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010166" MajorTopicYN="N">Palliative Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004561" MajorTopicYN="N">Transcutaneous Electric Nerve Stimulation</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC1291628</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1988</Year><Month>6</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1988</Year><Month>6</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1988</Year><Month>6</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2457110</ArticleId><ArticleId IdType="pmc">PMC1291628</ArticleId><ArticleId IdType="doi">10.1177/014107688808100615</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006185 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 006185 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:2457110
|texte= The management of symptoms in advanced cancer: experience in a hospital-based continuing care unit.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:2457110" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |