A study of the CD4: CD8 ratio in peripheral T lymphocytes of rural Papua New Guineans: a reduced ratio assessed with regard to infectious agents.
Identifieur interne : 005692 ( PubMed/Corpus ); précédent : 005691; suivant : 005693A study of the CD4: CD8 ratio in peripheral T lymphocytes of rural Papua New Guineans: a reduced ratio assessed with regard to infectious agents.
Auteurs : P F TurnerSource :
- Papua and New Guinea medical journal [ 0031-1480 ] ; 1993.
English descriptors
- KwdEn :
- Adolescent, Adult, Age Distribution, Aged, Animals, CD4-CD8 Ratio, Child, Child, Preschool, Elephantiasis, Filarial (blood), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (immunology), Female, HIV Infections (blood), HIV Infections (epidemiology), HIV Infections (immunology), HIV-1, Hepatitis B (blood), Hepatitis B (epidemiology), Hepatitis B (immunology), Hepatitis B Surface Antigens (blood), Humans, Male, Middle Aged, Papua New Guinea (epidemiology), Population Surveillance, Prevalence, Rural Population, Seroepidemiologic Studies, Tuberculin Test, Tuberculosis (blood), Tuberculosis (epidemiology), Tuberculosis (immunology), Wuchereria bancrofti.
- MESH :
- chemical , blood : Hepatitis B Surface Antigens.
- geographic , epidemiology : Papua New Guinea.
- blood : Elephantiasis, Filarial, HIV Infections, Hepatitis B, Tuberculosis.
- epidemiology : Elephantiasis, Filarial, HIV Infections, Hepatitis B, Tuberculosis.
- immunology : Elephantiasis, Filarial, HIV Infections, Hepatitis B, Tuberculosis.
- Adolescent, Adult, Age Distribution, Aged, Animals, CD4-CD8 Ratio, Child, Child, Preschool, Female, HIV-1, Humans, Male, Middle Aged, Population Surveillance, Prevalence, Rural Population, Seroepidemiologic Studies, Tuberculin Test, Wuchereria bancrofti.
Abstract
The CD4:CD8 ratio in peripheral T lymphocytes was determined in 123 Papua New Guineans aged over 5 years from Rumginae, a rural area of the Western Province. 18 people had a ratio less than 1.0. No antibody response to human immunodeficiency virus 1 (HIV 1) was found within the group. Hepatitis B surface antigen was more commonly associated with a CD4:CD8 ratio less than 1.0 than were microfilaraemia or a positive Mantoux test. Hepatitis B infection may be one of the causes of the CD4:CD8 ratio reduction within the community. Irrespective of the cause, other studies in Papua New Guinea have shown that a CD4:CD8 ratio less than 1.0 may result more from an increase in the CD8 cell count than a reduction in the CD4 cell count.
PubMed: 8059546
Links to Exploration step
pubmed:8059546Le document en format XML
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<author><name sortKey="Turner, P F" sort="Turner, P F" uniqKey="Turner P" first="P F" last="Turner">P F Turner</name>
<affiliation><nlm:affiliation>Anton Breinl Centre for Tropical Health and Medicine, James Cook University of North Queensland, Townsville, Australia.</nlm:affiliation>
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<affiliation><nlm:affiliation>Anton Breinl Centre for Tropical Health and Medicine, James Cook University of North Queensland, Townsville, Australia.</nlm:affiliation>
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<series><title level="j">Papua and New Guinea medical journal</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Age Distribution</term>
<term>Aged</term>
<term>Animals</term>
<term>CD4-CD8 Ratio</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Elephantiasis, Filarial (blood)</term>
<term>Elephantiasis, Filarial (epidemiology)</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Female</term>
<term>HIV Infections (blood)</term>
<term>HIV Infections (epidemiology)</term>
<term>HIV Infections (immunology)</term>
<term>HIV-1</term>
<term>Hepatitis B (blood)</term>
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<term>Humans</term>
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<term>Papua New Guinea (epidemiology)</term>
<term>Population Surveillance</term>
<term>Prevalence</term>
<term>Rural Population</term>
<term>Seroepidemiologic Studies</term>
<term>Tuberculin Test</term>
<term>Tuberculosis (blood)</term>
<term>Tuberculosis (epidemiology)</term>
<term>Tuberculosis (immunology)</term>
<term>Wuchereria bancrofti</term>
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<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Hepatitis B Surface Antigens</term>
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<term>Tuberculosis</term>
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<term>Adult</term>
<term>Age Distribution</term>
<term>Aged</term>
<term>Animals</term>
<term>CD4-CD8 Ratio</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Female</term>
<term>HIV-1</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Population Surveillance</term>
<term>Prevalence</term>
<term>Rural Population</term>
<term>Seroepidemiologic Studies</term>
<term>Tuberculin Test</term>
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<front><div type="abstract" xml:lang="en">The CD4:CD8 ratio in peripheral T lymphocytes was determined in 123 Papua New Guineans aged over 5 years from Rumginae, a rural area of the Western Province. 18 people had a ratio less than 1.0. No antibody response to human immunodeficiency virus 1 (HIV 1) was found within the group. Hepatitis B surface antigen was more commonly associated with a CD4:CD8 ratio less than 1.0 than were microfilaraemia or a positive Mantoux test. Hepatitis B infection may be one of the causes of the CD4:CD8 ratio reduction within the community. Irrespective of the cause, other studies in Papua New Guinea have shown that a CD4:CD8 ratio less than 1.0 may result more from an increase in the CD8 cell count than a reduction in the CD4 cell count.</div>
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<Title>Papua and New Guinea medical journal</Title>
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<ArticleTitle>A study of the CD4: CD8 ratio in peripheral T lymphocytes of rural Papua New Guineans: a reduced ratio assessed with regard to infectious agents.</ArticleTitle>
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<Abstract><AbstractText>The CD4:CD8 ratio in peripheral T lymphocytes was determined in 123 Papua New Guineans aged over 5 years from Rumginae, a rural area of the Western Province. 18 people had a ratio less than 1.0. No antibody response to human immunodeficiency virus 1 (HIV 1) was found within the group. Hepatitis B surface antigen was more commonly associated with a CD4:CD8 ratio less than 1.0 than were microfilaraemia or a positive Mantoux test. Hepatitis B infection may be one of the causes of the CD4:CD8 ratio reduction within the community. Irrespective of the cause, other studies in Papua New Guinea have shown that a CD4:CD8 ratio less than 1.0 may result more from an increase in the CD8 cell count than a reduction in the CD4 cell count.</AbstractText>
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