Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.
Identifieur interne : 004C66 ( PubMed/Corpus ); précédent : 004C65; suivant : 004C67Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.
Auteurs : M A Kron ; B. Ramirez ; V. Belizario ; J P PandeySource :
- Experimental and clinical immunogenetics [ 0254-9670 ] ; 1999.
English descriptors
- KwdEn :
- Asian Continental Ancestry Group (genetics), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (ethnology), Elephantiasis, Filarial (genetics), Haplotypes, Humans, Immunoglobulin Allotypes (genetics), Immunoglobulin Gm Allotypes (genetics), Phenotype, Philippines (epidemiology), Prevalence.
- MESH :
- chemical , genetics : Immunoglobulin Allotypes, Immunoglobulin Gm Allotypes.
- geographic , epidemiology : Philippines.
- epidemiology : Elephantiasis, Filarial.
- ethnology : Elephantiasis, Filarial.
- genetics : Asian Continental Ancestry Group, Elephantiasis, Filarial.
- Haplotypes, Humans, Phenotype, Prevalence.
Abstract
Immunoglobulin (Ig) allotypes are polymorphic genetic systems that show distinct racial arrays, thus making them powerful tools for studies of genetic admixture and biological relationships. In the province of Sorsogon, southern Luzon, Philippines, allotyping was completed on 252 persons residing in two neighboring villages. The people demonstrated 14 GM and 3 KM phenotypes. The frequency of homozygous KM3, KM1 and heterozygous KM1,3 was identical in these villages; however, half of the GM phenotypes present in one village were significantly less frequent in the other village. The frequency of KM and GM haplotypes was different from those reported in Filipino aboriginal groups, but similar to a population on Samar Island, the only other Filipino group for which Ig allotype data exist. Variability in the prevalence of parasitic disease such as lymphatic filariasis may in part reflect differences in genetic susceptibility, resulting from allotypic heterogeneity between villages.
DOI: 19097
PubMed: 10343157
Links to Exploration step
pubmed:10343157Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.</title><author><name sortKey="Kron, M A" sort="Kron, M A" uniqKey="Kron M" first="M A" last="Kron">M A Kron</name><affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases, Michigan State University, East Lansing 49924, USA. kron@pilot.msu.edu</nlm:affiliation></affiliation></author><author><name sortKey="Ramirez, B" sort="Ramirez, B" uniqKey="Ramirez B" first="B" last="Ramirez">B. Ramirez</name></author><author><name sortKey="Belizario, V" sort="Belizario, V" uniqKey="Belizario V" first="V" last="Belizario">V. Belizario</name></author><author><name sortKey="Pandey, J P" sort="Pandey, J P" uniqKey="Pandey J" first="J P" last="Pandey">J P Pandey</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1999">1999</date><idno type="RBID">pubmed:10343157</idno><idno type="pmid">10343157</idno><idno type="doi">19097</idno><idno type="wicri:Area/PubMed/Corpus">004C66</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">004C66</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.</title><author><name sortKey="Kron, M A" sort="Kron, M A" uniqKey="Kron M" first="M A" last="Kron">M A Kron</name><affiliation><nlm:affiliation>Department of Medicine, Division of Infectious Diseases, Michigan State University, East Lansing 49924, USA. kron@pilot.msu.edu</nlm:affiliation></affiliation></author><author><name sortKey="Ramirez, B" sort="Ramirez, B" uniqKey="Ramirez B" first="B" last="Ramirez">B. Ramirez</name></author><author><name sortKey="Belizario, V" sort="Belizario, V" uniqKey="Belizario V" first="V" last="Belizario">V. Belizario</name></author><author><name sortKey="Pandey, J P" sort="Pandey, J P" uniqKey="Pandey J" first="J P" last="Pandey">J P Pandey</name></author></analytic><series><title level="j">Experimental and clinical immunogenetics</title><idno type="ISSN">0254-9670</idno><imprint><date when="1999" type="published">1999</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Asian Continental Ancestry Group (genetics)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (ethnology)</term><term>Elephantiasis, Filarial (genetics)</term><term>Haplotypes</term><term>Humans</term><term>Immunoglobulin Allotypes (genetics)</term><term>Immunoglobulin Gm Allotypes (genetics)</term><term>Phenotype</term><term>Philippines (epidemiology)</term><term>Prevalence</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Immunoglobulin Allotypes</term><term>Immunoglobulin Gm Allotypes</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Philippines</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="ethnology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Asian Continental Ancestry Group</term><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Haplotypes</term><term>Humans</term><term>Phenotype</term><term>Prevalence</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Immunoglobulin (Ig) allotypes are polymorphic genetic systems that show distinct racial arrays, thus making them powerful tools for studies of genetic admixture and biological relationships. In the province of Sorsogon, southern Luzon, Philippines, allotyping was completed on 252 persons residing in two neighboring villages. The people demonstrated 14 GM and 3 KM phenotypes. The frequency of homozygous KM3, KM1 and heterozygous KM1,3 was identical in these villages; however, half of the GM phenotypes present in one village were significantly less frequent in the other village. The frequency of KM and GM haplotypes was different from those reported in Filipino aboriginal groups, but similar to a population on Samar Island, the only other Filipino group for which Ig allotype data exist. Variability in the prevalence of parasitic disease such as lymphatic filariasis may in part reflect differences in genetic susceptibility, resulting from allotypic heterogeneity between villages.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10343157</PMID><DateCreated><Year>1999</Year><Month>07</Month><Day>13</Day></DateCreated><DateCompleted><Year>1999</Year><Month>07</Month><Day>13</Day></DateCompleted><DateRevised><Year>2007</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0254-9670</ISSN><JournalIssue CitedMedium="Print"><Volume>16</Volume><Issue>2</Issue><PubDate><Year>1999</Year></PubDate></JournalIssue><Title>Experimental and clinical immunogenetics</Title><ISOAbbreviation>Exp. Clin. Immunogenet.</ISOAbbreviation></Journal><ArticleTitle>Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.</ArticleTitle><Pagination><MedlinePgn>65-71</MedlinePgn></Pagination><Abstract><AbstractText>Immunoglobulin (Ig) allotypes are polymorphic genetic systems that show distinct racial arrays, thus making them powerful tools for studies of genetic admixture and biological relationships. In the province of Sorsogon, southern Luzon, Philippines, allotyping was completed on 252 persons residing in two neighboring villages. The people demonstrated 14 GM and 3 KM phenotypes. The frequency of homozygous KM3, KM1 and heterozygous KM1,3 was identical in these villages; however, half of the GM phenotypes present in one village were significantly less frequent in the other village. The frequency of KM and GM haplotypes was different from those reported in Filipino aboriginal groups, but similar to a population on Samar Island, the only other Filipino group for which Ig allotype data exist. Variability in the prevalence of parasitic disease such as lymphatic filariasis may in part reflect differences in genetic susceptibility, resulting from allotypic heterogeneity between villages.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kron</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Department of Medicine, Division of Infectious Diseases, Michigan State University, East Lansing 49924, USA. kron@pilot.msu.edu</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Ramirez</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Belizario</LastName><ForeName>V</ForeName><Initials>V</Initials><Suffix>Jr</Suffix></Author><Author ValidYN="Y"><LastName>Pandey</LastName><ForeName>J P</ForeName><Initials>JP</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>1P50A130601</GrantID><Agency>PHS HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>K11AI10119</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>R29AI3768</GrantID><Acronym>AI</Acronym><Agency>NIAID NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Exp Clin Immunogenet</MedlineTA><NlmUniqueID>8411714</NlmUniqueID><ISSNLinking>0254-9670</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007126">Immunoglobulin Allotypes</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007129">Immunoglobulin Gm Allotypes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D044466" MajorTopicYN="N">Asian Continental Ancestry Group</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000208" MajorTopicYN="N">ethnology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006239" MajorTopicYN="N">Haplotypes</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007126" MajorTopicYN="N">Immunoglobulin Allotypes</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007129" MajorTopicYN="N">Immunoglobulin Gm Allotypes</DescriptorName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010641" MajorTopicYN="N">Phenotype</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010679" MajorTopicYN="N" Type="Geographic">Philippines</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1999</Year><Month>5</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>3</Month><Day>28</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1999</Year><Month>5</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">10343157</ArticleId><ArticleId IdType="pii">19097</ArticleId><ArticleId IdType="doi">19097</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004C66 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 004C66 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:10343157
|texte= Immunoglobulin allotypes among the Bicolanos of Sorsogon province, Luzon, Philippines: implications of phenotypes for filariasis.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:10343157" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |