Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma.
Identifieur interne : 004955 ( PubMed/Corpus ); précédent : 004954; suivant : 004956Vulvar hypertrophy with lymphedema. A mimicker of aggressive angiomyxoma.
Auteurs : R. Vang ; J H Connelly ; H A Hammill ; R L ShannonSource :
- Archives of pathology & laboratory medicine [ 0003-9985 ] ; 2000.
English descriptors
- KwdEn :
- MESH :
- pathology : Lymphedema, Myxoma, Vulva, Vulvar Neoplasms.
- Adult, Diagnosis, Differential, Female, Humans, Hypertrophy.
Abstract
We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thick-walled vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma.
DOI: 10.1043/0003-9985(2000)124<1697:VHWL>2.0.CO;2
PubMed: 11079029
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pubmed:11079029Le document en format XML
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<affiliation><nlm:affiliation>Department of Pathology and Laboratory Medicine, University of Texas Medical School, Houston, TX, USA.</nlm:affiliation>
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<author><name sortKey="Connelly, J H" sort="Connelly, J H" uniqKey="Connelly J" first="J H" last="Connelly">J H Connelly</name>
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<author><name sortKey="Hammill, H A" sort="Hammill, H A" uniqKey="Hammill H" first="H A" last="Hammill">H A Hammill</name>
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<author><name sortKey="Shannon, R L" sort="Shannon, R L" uniqKey="Shannon R" first="R L" last="Shannon">R L Shannon</name>
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<author><name sortKey="Vang, R" sort="Vang, R" uniqKey="Vang R" first="R" last="Vang">R. Vang</name>
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<author><name sortKey="Hammill, H A" sort="Hammill, H A" uniqKey="Hammill H" first="H A" last="Hammill">H A Hammill</name>
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<author><name sortKey="Shannon, R L" sort="Shannon, R L" uniqKey="Shannon R" first="R L" last="Shannon">R L Shannon</name>
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<term>Hypertrophy</term>
<term>Lymphedema (pathology)</term>
<term>Myxoma (pathology)</term>
<term>Vulva (pathology)</term>
<term>Vulvar Neoplasms (pathology)</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphedema</term>
<term>Myxoma</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
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<front><div type="abstract" xml:lang="en">We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thick-walled vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma.</div>
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<Title>Archives of pathology & laboratory medicine</Title>
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<Abstract><AbstractText>We report the case of a 43-year-old quadriplegic woman with bilateral vulvar enlargement. The clinical impression was labial hypertrophy, but the microscopic features mimicked aggressive angiomyxoma because of the location, hypocellular proliferation of fibroblastic cells in an edematous-myxoid stroma, and vessels with perivascular collagen deposition, which simulated the thick-walled vessels of aggressive angiomyxoma. Since the lesion lacked true thick-walled vessels and contained ectatic tortuous lymphatics, the pathologic interpretation was lymphedema. This vulvar lesion should be recognized to prevent the misdiagnosis of aggressive angiomyxoma.</AbstractText>
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