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Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.

Identifieur interne : 003953 ( PubMed/Corpus ); précédent : 003952; suivant : 003954

Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.

Auteurs : M. De Vries ; W G Vonkeman ; R J Van Ginkel ; H J Hoekstra

Source :

RBID : pubmed:16806794

English descriptors

Abstract

Aim of the study was to assess the short-term and long-term morbidity after inguinal sentinel lymph node biopsy (SLNB) with or without completion groin dissection (GD) in patients with cutaneous melanoma.

DOI: 10.1016/j.ejso.2006.05.003
PubMed: 16806794

Links to Exploration step

pubmed:16806794

Le document en format XML

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<title xml:lang="en">Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.</title>
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<name sortKey="De Vries, M" sort="De Vries, M" uniqKey="De Vries M" first="M" last="De Vries">M. De Vries</name>
<affiliation>
<nlm:affiliation>Department of Surgical Oncology, University Medical Center Groningen and Groningen University, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Vonkeman, W G" sort="Vonkeman, W G" uniqKey="Vonkeman W" first="W G" last="Vonkeman">W G Vonkeman</name>
</author>
<author>
<name sortKey="Van Ginkel, R J" sort="Van Ginkel, R J" uniqKey="Van Ginkel R" first="R J" last="Van Ginkel">R J Van Ginkel</name>
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<author>
<name sortKey="Hoekstra, H J" sort="Hoekstra, H J" uniqKey="Hoekstra H" first="H J" last="Hoekstra">H J Hoekstra</name>
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<title xml:lang="en">Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.</title>
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<name sortKey="De Vries, M" sort="De Vries, M" uniqKey="De Vries M" first="M" last="De Vries">M. De Vries</name>
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<nlm:affiliation>Department of Surgical Oncology, University Medical Center Groningen and Groningen University, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.</nlm:affiliation>
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<name sortKey="Vonkeman, W G" sort="Vonkeman, W G" uniqKey="Vonkeman W" first="W G" last="Vonkeman">W G Vonkeman</name>
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<name sortKey="Van Ginkel, R J" sort="Van Ginkel, R J" uniqKey="Van Ginkel R" first="R J" last="Van Ginkel">R J Van Ginkel</name>
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<name sortKey="Hoekstra, H J" sort="Hoekstra, H J" uniqKey="Hoekstra H" first="H J" last="Hoekstra">H J Hoekstra</name>
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<series>
<title level="j">European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology</title>
<idno type="ISSN">0748-7983</idno>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Groin</term>
<term>Humans</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymphatic Metastasis</term>
<term>Lymphedema (etiology)</term>
<term>Male</term>
<term>Melanoma (secondary)</term>
<term>Melanoma (surgery)</term>
<term>Middle Aged</term>
<term>Postoperative Hemorrhage (etiology)</term>
<term>Sentinel Lymph Node Biopsy (adverse effects)</term>
<term>Seroma (etiology)</term>
<term>Skin Neoplasms (pathology)</term>
<term>Surgical Wound Infection</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lymph Node Excision</term>
<term>Sentinel Lymph Node Biopsy</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
<term>Postoperative Hemorrhage</term>
<term>Seroma</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="secondary" xml:lang="en">
<term>Melanoma</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Melanoma</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Groin</term>
<term>Humans</term>
<term>Lymphatic Metastasis</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Surgical Wound Infection</term>
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<front>
<div type="abstract" xml:lang="en">Aim of the study was to assess the short-term and long-term morbidity after inguinal sentinel lymph node biopsy (SLNB) with or without completion groin dissection (GD) in patients with cutaneous melanoma.</div>
</front>
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<DateCreated>
<Year>2006</Year>
<Month>08</Month>
<Day>28</Day>
</DateCreated>
<DateCompleted>
<Year>2006</Year>
<Month>11</Month>
<Day>30</Day>
</DateCompleted>
<DateRevised>
<Year>2007</Year>
<Month>07</Month>
<Day>02</Day>
</DateRevised>
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<ISSN IssnType="Print">0748-7983</ISSN>
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<Volume>32</Volume>
<Issue>7</Issue>
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<Year>2006</Year>
<Month>Sep</Month>
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<Title>European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology</Title>
<ISOAbbreviation>Eur J Surg Oncol</ISOAbbreviation>
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<ArticleTitle>Morbidity after inguinal sentinel lymph node biopsy and completion lymph node dissection in patients with cutaneous melanoma.</ArticleTitle>
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<MedlinePgn>785-9</MedlinePgn>
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<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Aim of the study was to assess the short-term and long-term morbidity after inguinal sentinel lymph node biopsy (SLNB) with or without completion groin dissection (GD) in patients with cutaneous melanoma.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Between 1995 and 2003, 127 inguinal SLNBs were performed for cutaneous melanoma. Sixty-six patients, median age 50 (18-77) years, met the inclusion criteria and were studied. Short-term complications were analysed retrospectively, while long-term complications were evaluated using volume measurement and range of motion measurement of the lower extremities.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Fifty-two patients underwent SLNB alone (SLNB group) and 14 patients underwent completion groin dissection after tumour-positive SLNB (SLNB/GD group). Morbidity after SLNB alone: wound infections (n=1), seroma (n=1), postoperative bleeding (n=1), erysipelas (n=1), and slight lymphedema 6% (n=3). Morbidity after SLNB/GD: wound infections (n=4), seroma (n=1), wound necrosis (n=1), postoperative bleeding (n=1), and slight lymphedema 64% (n=9). There were differences between the two groups in the total number of short-term complications (p<0.001), volume difference (p<0.001), flexion (p=0.009), and abduction (p=0.011) limitation of the hip joint.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Inguinal SLNB is accompanied with a low complication rate. However, SLNB followed by groin dissection is associated with an increased risk of wound infection and slight lymphedema.</AbstractText>
</Abstract>
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<LastName>de Vries</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
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<Affiliation>Department of Surgical Oncology, University Medical Center Groningen and Groningen University, Hanzeplein 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.</Affiliation>
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<Language>eng</Language>
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<DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
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<DescriptorName UI="D006119" MajorTopicYN="N">Groin</DescriptorName>
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<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName>
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<DescriptorName UI="D008545" MajorTopicYN="N">Melanoma</DescriptorName>
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<DescriptorName UI="D019106" MajorTopicYN="N">Postoperative Hemorrhage</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
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<DescriptorName UI="D021701" MajorTopicYN="N">Sentinel Lymph Node Biopsy</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
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<DescriptorName UI="D049291" MajorTopicYN="N">Seroma</DescriptorName>
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<DescriptorName UI="D012878" MajorTopicYN="N">Skin Neoplasms</DescriptorName>
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