Lymphedema tarda after liver transplantation: a case report and review of the literature.
Identifieur interne : 003777 ( PubMed/Corpus ); précédent : 003776; suivant : 003778Lymphedema tarda after liver transplantation: a case report and review of the literature.
Auteurs : Sammy Saab ; Stephen Nguyen ; James Collins ; Gregg Kunder ; Ronald W. BusuttilSource :
- Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation [ 1304-0855 ] ; 2006.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Antiviral Agents.
- adverse effects : Liver Transplantation.
- diagnosis : Ascites, Lymphedema.
- etiology : Liver Diseases.
- surgery : Hepatitis C, Liver Diseases, Liver Diseases, Alcoholic.
- Humans, Male, Middle Aged, Treatment Outcome.
Abstract
We present a patient with lymphedema that developed after orthotopic liver transplantation. The cause of the posttransplant lymphedema was likely related to a developmental abnormality of the lymphatic system that was exaggerated by refractory chylous ascites. A peritoneal fluid with a milky appearance, chylous ascites is rich in triglyceride and is caused by the obstruction or disruption of abdominal lymphatic channels. It is a rare complication that may develop after trauma or abdominal surgery or as a result of a malignant disease, and it is even more uncommon after liver transplantation. Therapy for chylous ascites involves treating its underlying cause. In the patient we describe, lymphedema tarda, which was diagnosed 6 months after liver transplantation, was likely caused by chylous ascites and a developmental abnormality of the lymphatic system.
PubMed: 17238860
Links to Exploration step
pubmed:17238860Le document en format XML
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<author><name sortKey="Saab, Sammy" sort="Saab, Sammy" uniqKey="Saab S" first="Sammy" last="Saab">Sammy Saab</name>
<affiliation><nlm:affiliation>Department of Medicine, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California 90095-7302, USA. Ssaab@mednet.ucla.edu</nlm:affiliation>
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</author>
<author><name sortKey="Nguyen, Stephen" sort="Nguyen, Stephen" uniqKey="Nguyen S" first="Stephen" last="Nguyen">Stephen Nguyen</name>
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<author><name sortKey="Collins, James" sort="Collins, James" uniqKey="Collins J" first="James" last="Collins">James Collins</name>
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<author><name sortKey="Kunder, Gregg" sort="Kunder, Gregg" uniqKey="Kunder G" first="Gregg" last="Kunder">Gregg Kunder</name>
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<author><name sortKey="Busuttil, Ronald W" sort="Busuttil, Ronald W" uniqKey="Busuttil R" first="Ronald W" last="Busuttil">Ronald W. Busuttil</name>
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<affiliation><nlm:affiliation>Department of Medicine, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, California 90095-7302, USA. Ssaab@mednet.ucla.edu</nlm:affiliation>
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<author><name sortKey="Nguyen, Stephen" sort="Nguyen, Stephen" uniqKey="Nguyen S" first="Stephen" last="Nguyen">Stephen Nguyen</name>
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<series><title level="j">Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiviral Agents (therapeutic use)</term>
<term>Ascites (diagnosis)</term>
<term>Hepatitis C (surgery)</term>
<term>Humans</term>
<term>Liver Diseases (etiology)</term>
<term>Liver Diseases (surgery)</term>
<term>Liver Diseases, Alcoholic (surgery)</term>
<term>Liver Transplantation (adverse effects)</term>
<term>Lymphedema (diagnosis)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Treatment Outcome</term>
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<term>Liver Diseases, Alcoholic</term>
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<front><div type="abstract" xml:lang="en">We present a patient with lymphedema that developed after orthotopic liver transplantation. The cause of the posttransplant lymphedema was likely related to a developmental abnormality of the lymphatic system that was exaggerated by refractory chylous ascites. A peritoneal fluid with a milky appearance, chylous ascites is rich in triglyceride and is caused by the obstruction or disruption of abdominal lymphatic channels. It is a rare complication that may develop after trauma or abdominal surgery or as a result of a malignant disease, and it is even more uncommon after liver transplantation. Therapy for chylous ascites involves treating its underlying cause. In the patient we describe, lymphedema tarda, which was diagnosed 6 months after liver transplantation, was likely caused by chylous ascites and a developmental abnormality of the lymphatic system.</div>
</front>
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<Abstract><AbstractText>We present a patient with lymphedema that developed after orthotopic liver transplantation. The cause of the posttransplant lymphedema was likely related to a developmental abnormality of the lymphatic system that was exaggerated by refractory chylous ascites. A peritoneal fluid with a milky appearance, chylous ascites is rich in triglyceride and is caused by the obstruction or disruption of abdominal lymphatic channels. It is a rare complication that may develop after trauma or abdominal surgery or as a result of a malignant disease, and it is even more uncommon after liver transplantation. Therapy for chylous ascites involves treating its underlying cause. In the patient we describe, lymphedema tarda, which was diagnosed 6 months after liver transplantation, was likely caused by chylous ascites and a developmental abnormality of the lymphatic system.</AbstractText>
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