99mTc-MIBI imaging of cutaneous AIDS-associated Kaposi's sarcoma.
Identifieur interne : 003767 ( PubMed/Corpus ); précédent : 003766; suivant : 00376899mTc-MIBI imaging of cutaneous AIDS-associated Kaposi's sarcoma.
Auteurs : Fawzia I. Peer ; Margaret H. Pui ; Anisa Mosam ; William I D. RaeSource :
- International journal of dermatology [ 0011-9059 ] ; 2007.
English descriptors
- KwdEn :
- Acquired Immunodeficiency Syndrome (complications), Adult, Aged, Extremities, Female, Humans, Lymphatic Metastasis (diagnostic imaging), Lymphedema (complications), Lymphedema (diagnostic imaging), Male, Middle Aged, Neoplasm Staging, Radionuclide Imaging, Radiopharmaceuticals, Sarcoma, Kaposi (complications), Sarcoma, Kaposi (diagnostic imaging), Skin Neoplasms (complications), Skin Neoplasms (diagnostic imaging), Technetium Tc 99m Sestamibi, Whole Body Imaging.
- MESH :
- chemical : Radiopharmaceuticals, Technetium Tc 99m Sestamibi.
- complications : Acquired Immunodeficiency Syndrome, Lymphedema, Sarcoma, Kaposi, Skin Neoplasms.
- diagnostic imaging : Lymphatic Metastasis, Lymphedema, Sarcoma, Kaposi, Skin Neoplasms.
- Adult, Aged, Extremities, Female, Humans, Male, Middle Aged, Neoplasm Staging, Radionuclide Imaging, Whole Body Imaging.
Abstract
Kapoksi's sarcoma (KS) is a common neoplasm complicating acquired immunodeficiency syndrome (AIDS). Skin, mucus membranes, lymph nodes, gastrointestinal tract and lungs may be involved. Kaposi's sarcoma has been demonstrated by scintigraphy, and a (99m)Tc-hexakis-2-methoxy isobutyl isonitrile (MIBI) scan can demonstrate lymphoma and tumors of the brain, nasopharynx, thyroid, parathyroid, lung, breast and kidney. It may also be useful for detecting and delineating the extent of KS. The objective of this study was to determine the efficacy of (99m)Tc-MIBI scanning to demonstrate cutaneous AIDS-associated KS, lymphedema and lymphadenopathy in the extremities.
DOI: 10.1111/j.1365-4632.2006.03001.x
PubMed: 17269969
Links to Exploration step
pubmed:17269969Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">99mTc-MIBI imaging of cutaneous AIDS-associated Kaposi's sarcoma.</title>
<author><name sortKey="Peer, Fawzia I" sort="Peer, Fawzia I" uniqKey="Peer F" first="Fawzia I" last="Peer">Fawzia I. Peer</name>
<affiliation><nlm:affiliation>Department of Radiography, Durban Institute of Technology, Durban, South Africa.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Pui, Margaret H" sort="Pui, Margaret H" uniqKey="Pui M" first="Margaret H" last="Pui">Margaret H. Pui</name>
</author>
<author><name sortKey="Mosam, Anisa" sort="Mosam, Anisa" uniqKey="Mosam A" first="Anisa" last="Mosam">Anisa Mosam</name>
</author>
<author><name sortKey="Rae, William I D" sort="Rae, William I D" uniqKey="Rae W" first="William I D" last="Rae">William I D. Rae</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">99mTc-MIBI imaging of cutaneous AIDS-associated Kaposi's sarcoma.</title>
<author><name sortKey="Peer, Fawzia I" sort="Peer, Fawzia I" uniqKey="Peer F" first="Fawzia I" last="Peer">Fawzia I. Peer</name>
<affiliation><nlm:affiliation>Department of Radiography, Durban Institute of Technology, Durban, South Africa.</nlm:affiliation>
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<author><name sortKey="Pui, Margaret H" sort="Pui, Margaret H" uniqKey="Pui M" first="Margaret H" last="Pui">Margaret H. Pui</name>
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<author><name sortKey="Mosam, Anisa" sort="Mosam, Anisa" uniqKey="Mosam A" first="Anisa" last="Mosam">Anisa Mosam</name>
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<author><name sortKey="Rae, William I D" sort="Rae, William I D" uniqKey="Rae W" first="William I D" last="Rae">William I D. Rae</name>
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<series><title level="j">International journal of dermatology</title>
<idno type="ISSN">0011-9059</idno>
<imprint><date when="2007" type="published">2007</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Acquired Immunodeficiency Syndrome (complications)</term>
<term>Adult</term>
<term>Aged</term>
<term>Extremities</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphatic Metastasis (diagnostic imaging)</term>
<term>Lymphedema (complications)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Radionuclide Imaging</term>
<term>Radiopharmaceuticals</term>
<term>Sarcoma, Kaposi (complications)</term>
<term>Sarcoma, Kaposi (diagnostic imaging)</term>
<term>Skin Neoplasms (complications)</term>
<term>Skin Neoplasms (diagnostic imaging)</term>
<term>Technetium Tc 99m Sestamibi</term>
<term>Whole Body Imaging</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Radiopharmaceuticals</term>
<term>Technetium Tc 99m Sestamibi</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Acquired Immunodeficiency Syndrome</term>
<term>Lymphedema</term>
<term>Sarcoma, Kaposi</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lymphatic Metastasis</term>
<term>Lymphedema</term>
<term>Sarcoma, Kaposi</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Extremities</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasm Staging</term>
<term>Radionuclide Imaging</term>
<term>Whole Body Imaging</term>
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<front><div type="abstract" xml:lang="en">Kapoksi's sarcoma (KS) is a common neoplasm complicating acquired immunodeficiency syndrome (AIDS). Skin, mucus membranes, lymph nodes, gastrointestinal tract and lungs may be involved. Kaposi's sarcoma has been demonstrated by scintigraphy, and a (99m)Tc-hexakis-2-methoxy isobutyl isonitrile (MIBI) scan can demonstrate lymphoma and tumors of the brain, nasopharynx, thyroid, parathyroid, lung, breast and kidney. It may also be useful for detecting and delineating the extent of KS. The objective of this study was to determine the efficacy of (99m)Tc-MIBI scanning to demonstrate cutaneous AIDS-associated KS, lymphedema and lymphadenopathy in the extremities.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17269969</PMID>
<DateCreated><Year>2007</Year>
<Month>02</Month>
<Day>02</Day>
</DateCreated>
<DateCompleted><Year>2007</Year>
<Month>06</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>24</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0011-9059</ISSN>
<JournalIssue CitedMedium="Print"><Volume>46</Volume>
<Issue>2</Issue>
<PubDate><Year>2007</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>International journal of dermatology</Title>
<ISOAbbreviation>Int. J. Dermatol.</ISOAbbreviation>
</Journal>
<ArticleTitle>99mTc-MIBI imaging of cutaneous AIDS-associated Kaposi's sarcoma.</ArticleTitle>
<Pagination><MedlinePgn>166-71</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Kapoksi's sarcoma (KS) is a common neoplasm complicating acquired immunodeficiency syndrome (AIDS). Skin, mucus membranes, lymph nodes, gastrointestinal tract and lungs may be involved. Kaposi's sarcoma has been demonstrated by scintigraphy, and a (99m)Tc-hexakis-2-methoxy isobutyl isonitrile (MIBI) scan can demonstrate lymphoma and tumors of the brain, nasopharynx, thyroid, parathyroid, lung, breast and kidney. It may also be useful for detecting and delineating the extent of KS. The objective of this study was to determine the efficacy of (99m)Tc-MIBI scanning to demonstrate cutaneous AIDS-associated KS, lymphedema and lymphadenopathy in the extremities.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Whole body (99m)Tc-MIBI scans were obtained on 40 patients with AIDS-associated KS. Abnormal uptake of (99m)Tc-MIBI in the skin, subcutaneous soft tissues and lymph nodes was compared with the clinical assessment.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The (99m)Tc-MIBI uptake was noted in the cutaneous/subcutaneous KS of the extremities with a sensitivity of 73.53%, a specificity of 96.91% and an accuracy of 91.31%. Abnormal lymph nodes and lymphedema were detected in more patients on (99m)Tc-MIBI scans (33 and 18 patients) than clinical assessment (10 and 12 patients), respectively. Lymphedema of the lower extremity was found in four of 17 patients without any palpable or abnormal lymph node uptake of (99m)Tc-MIBI in the inguinal regions. Follow-up (99m)Tc-MIBI scans after treatment showed no uptake in the skin lesions and decreased uptake in the lymph nodes corresponding to complete clearing on clinical assessment.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">(99m)Tc-MIBI imaging provides additional information on the extent of lymph node involvement and more precise staging and therapeutic planning. It may be useful as a predictive test or follow up of response of cutaneous KS to treatment.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Peer</LastName>
<ForeName>Fawzia I</ForeName>
<Initials>FI</Initials>
<AffiliationInfo><Affiliation>Department of Radiography, Durban Institute of Technology, Durban, South Africa.</Affiliation>
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<Author ValidYN="Y"><LastName>Pui</LastName>
<ForeName>Margaret H</ForeName>
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<Author ValidYN="Y"><LastName>Mosam</LastName>
<ForeName>Anisa</ForeName>
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<Author ValidYN="Y"><LastName>Rae</LastName>
<ForeName>William I D</ForeName>
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<Language>eng</Language>
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<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Int J Dermatol</MedlineTA>
<NlmUniqueID>0243704</NlmUniqueID>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000163" MajorTopicYN="N">Acquired Immunodeficiency Syndrome</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D005121" MajorTopicYN="N">Extremities</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008207" MajorTopicYN="N">Lymphatic Metastasis</DescriptorName>
<QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName>
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<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName>
<QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009367" MajorTopicYN="N">Neoplasm Staging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011877" MajorTopicYN="N">Radionuclide Imaging</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D019275" MajorTopicYN="Y">Radiopharmaceuticals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012514" MajorTopicYN="N">Sarcoma, Kaposi</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012878" MajorTopicYN="N">Skin Neoplasms</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017256" MajorTopicYN="Y">Technetium Tc 99m Sestamibi</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051598" MajorTopicYN="N">Whole Body Imaging</DescriptorName>
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