Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.
Identifieur interne : 003263 ( PubMed/Corpus ); précédent : 003262; suivant : 003264Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.
Auteurs : Waldemar L. OlszewskiSource :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2008.
English descriptors
- KwdEn :
- MESH :
- pathology : Leg, Lymphatic System.
- physiology : Lymph, Lymphatic System, Muscle Contraction.
- physiopathology : Lymphedema.
- Humans.
Abstract
In healthy human leg, lymphatics contract spontaneously, rhythmically propelling lymph. The pressures generated by lymphatic contractions constitute the main force for lymph flow. This mechanism is of utmost importance during night rest, anesthesia, and immobilization, as well as in those with damaged peripheral motor neurons. Under physiological conditions, limb muscular activity and position only slightly change lymph flow. In obstructive lymphedema, lymphatic wall muscular fibers become damaged and the spontaneous contractility becomes ineffective in lymph transport because of low generated pressures and lymphatic valve insufficiency. The lymph-propelling task is taken over by leg muscle contractions. Measuring intralymphatic pressures and flow gives some insight into the mechanism of lymph flow in healthy limbs and loss of this function in lymphedema. This knowledge will be useful in the derivation of rational treatments for lymphedema.
DOI: 10.1196/annals.1413.010
PubMed: 18519964
Links to Exploration step
pubmed:18519964Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.</title><author><name sortKey="Olszewski, Waldemar L" sort="Olszewski, Waldemar L" uniqKey="Olszewski W" first="Waldemar L" last="Olszewski">Waldemar L. Olszewski</name><affiliation><nlm:affiliation>Department of Surgical Research and Transplantology, Medical Research Center, Polish Academy of Sciences, 5 Pawinskiego Str., 02 106 Warsaw, Poland. wlo@cmdik.pan.pl</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2008">2008</date><idno type="RBID">pubmed:18519964</idno><idno type="pmid">18519964</idno><idno type="doi">10.1196/annals.1413.010</idno><idno type="wicri:Area/PubMed/Corpus">003263</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003263</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.</title><author><name sortKey="Olszewski, Waldemar L" sort="Olszewski, Waldemar L" uniqKey="Olszewski W" first="Waldemar L" last="Olszewski">Waldemar L. Olszewski</name><affiliation><nlm:affiliation>Department of Surgical Research and Transplantology, Medical Research Center, Polish Academy of Sciences, 5 Pawinskiego Str., 02 106 Warsaw, Poland. wlo@cmdik.pan.pl</nlm:affiliation></affiliation></author></analytic><series><title level="j">Annals of the New York Academy of Sciences</title><idno type="ISSN">0077-8923</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans</term><term>Leg (pathology)</term><term>Lymph (physiology)</term><term>Lymphatic System (pathology)</term><term>Lymphatic System (physiology)</term><term>Lymphedema (physiopathology)</term><term>Muscle Contraction (physiology)</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Leg</term><term>Lymphatic System</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Lymph</term><term>Lymphatic System</term><term>Muscle Contraction</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In healthy human leg, lymphatics contract spontaneously, rhythmically propelling lymph. The pressures generated by lymphatic contractions constitute the main force for lymph flow. This mechanism is of utmost importance during night rest, anesthesia, and immobilization, as well as in those with damaged peripheral motor neurons. Under physiological conditions, limb muscular activity and position only slightly change lymph flow. In obstructive lymphedema, lymphatic wall muscular fibers become damaged and the spontaneous contractility becomes ineffective in lymph transport because of low generated pressures and lymphatic valve insufficiency. The lymph-propelling task is taken over by leg muscle contractions. Measuring intralymphatic pressures and flow gives some insight into the mechanism of lymph flow in healthy limbs and loss of this function in lymphedema. This knowledge will be useful in the derivation of rational treatments for lymphedema.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">18519964</PMID><DateCreated><Year>2008</Year><Month>06</Month><Day>03</Day></DateCreated><DateCompleted><Year>2008</Year><Month>07</Month><Day>03</Day></DateCompleted><DateRevised><Year>2008</Year><Month>06</Month><Day>03</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0077-8923</ISSN><JournalIssue CitedMedium="Print"><Volume>1131</Volume><PubDate><Year>2008</Year></PubDate></JournalIssue><Title>Annals of the New York Academy of Sciences</Title><ISOAbbreviation>Ann. N. Y. Acad. Sci.</ISOAbbreviation></Journal><ArticleTitle>Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.</ArticleTitle><Pagination><MedlinePgn>110-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1196/annals.1413.010</ELocationID><Abstract><AbstractText>In healthy human leg, lymphatics contract spontaneously, rhythmically propelling lymph. The pressures generated by lymphatic contractions constitute the main force for lymph flow. This mechanism is of utmost importance during night rest, anesthesia, and immobilization, as well as in those with damaged peripheral motor neurons. Under physiological conditions, limb muscular activity and position only slightly change lymph flow. In obstructive lymphedema, lymphatic wall muscular fibers become damaged and the spontaneous contractility becomes ineffective in lymph transport because of low generated pressures and lymphatic valve insufficiency. The lymph-propelling task is taken over by leg muscle contractions. Measuring intralymphatic pressures and flow gives some insight into the mechanism of lymph flow in healthy limbs and loss of this function in lymphedema. This knowledge will be useful in the derivation of rational treatments for lymphedema.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Olszewski</LastName><ForeName>Waldemar L</ForeName><Initials>WL</Initials><AffiliationInfo><Affiliation>Department of Surgical Research and Transplantology, Medical Research Center, Polish Academy of Sciences, 5 Pawinskiego Str., 02 106 Warsaw, Poland. wlo@cmdik.pan.pl</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Ann N Y Acad Sci</MedlineTA><NlmUniqueID>7506858</NlmUniqueID><ISSNLinking>0077-8923</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007866" MajorTopicYN="N">Leg</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008196" MajorTopicYN="N">Lymph</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008208" MajorTopicYN="N">Lymphatic System</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009119" MajorTopicYN="N">Muscle Contraction</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading></MeshHeadingList><NumberOfReferences>9</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2008</Year><Month>6</Month><Day>4</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>7</Month><Day>4</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2008</Year><Month>6</Month><Day>4</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">18519964</ArticleId><ArticleId IdType="pii">1131/1/110</ArticleId><ArticleId IdType="doi">10.1196/annals.1413.010</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003263 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 003263 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:18519964
|texte= Contractility patterns of human leg lymphatics in various stages of obstructive lymphedema.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:18519964" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |