The post-thrombotic syndrome - a condition to prevent.
Identifieur interne : 003199 ( PubMed/Corpus ); précédent : 003198; suivant : 003200The post-thrombotic syndrome - a condition to prevent.
Auteurs : Delphine Pirard ; Bernard Bellens ; Pierre VereeckenSource :
- Dermatology online journal [ 1087-2108 ] ; 2008.
English descriptors
- KwdEn :
- Anticoagulants (therapeutic use), Erysipelas (etiology), Erysipelas (pathology), Humans, Leg Dermatoses (etiology), Leg Dermatoses (pathology), Lymphangiosarcoma (etiology), Lymphedema (etiology), Lymphedema (pathology), Postthrombotic Syndrome (diagnosis), Postthrombotic Syndrome (etiology), Postthrombotic Syndrome (prevention & control), Skin (pathology), Skin Care, Skin Neoplasms (etiology), Stockings, Compression, Venous Thrombosis (complications), Venous Thrombosis (therapy).
- MESH :
- chemical , therapeutic use : Anticoagulants.
- complications : Venous Thrombosis.
- diagnosis : Postthrombotic Syndrome.
- etiology : Erysipelas, Leg Dermatoses, Lymphangiosarcoma, Lymphedema, Postthrombotic Syndrome, Skin Neoplasms.
- pathology : Erysipelas, Leg Dermatoses, Lymphedema, Skin.
- prevention & control : Postthrombotic Syndrome.
- therapy : Venous Thrombosis.
- Humans, Skin Care, Stockings, Compression.
Abstract
The incidence of the post-thrombotic syndrome (PTS) is increasing along with the incidence of deep vein thrombosis (DVT). The overall frequency of PTS ranges from 20 percent to 50 percent of DVT patients; severe PTS, which includes leg ulcers, occurs in a quarter of cases. Because of its severity and chronicity, PTS is associated with great morbidity and cost. Its diagnosis is primarily based on the presence of typical symptoms and signs, but objective evidence of venous valvular reflux can help to confirm the diagnosis. Because therapeutic options for PTS are extremely limited and results are often disappointing, prevention, recognition of clinical signs or complications, and early treatment remain the keys to reducing its morbidity. The prevention of DVT recurrence by anticoagulation and use of graduated compression stockings is likely to reduce the risk of PTS. There is no proven role for thrombolysis in preventing PTS.
PubMed: 18627714
Links to Exploration step
pubmed:18627714Le document en format XML
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<author><name sortKey="Pirard, Delphine" sort="Pirard, Delphine" uniqKey="Pirard D" first="Delphine" last="Pirard">Delphine Pirard</name>
<affiliation><nlm:affiliation>Department of Dermatology, Erasme hospital, Université Libre de Bruxelles Brussels, Belgium.</nlm:affiliation>
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<author><name sortKey="Bellens, Bernard" sort="Bellens, Bernard" uniqKey="Bellens B" first="Bernard" last="Bellens">Bernard Bellens</name>
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<author><name sortKey="Vereecken, Pierre" sort="Vereecken, Pierre" uniqKey="Vereecken P" first="Pierre" last="Vereecken">Pierre Vereecken</name>
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<author><name sortKey="Bellens, Bernard" sort="Bellens, Bernard" uniqKey="Bellens B" first="Bernard" last="Bellens">Bernard Bellens</name>
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<author><name sortKey="Vereecken, Pierre" sort="Vereecken, Pierre" uniqKey="Vereecken P" first="Pierre" last="Vereecken">Pierre Vereecken</name>
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<term>Erysipelas (pathology)</term>
<term>Humans</term>
<term>Leg Dermatoses (etiology)</term>
<term>Leg Dermatoses (pathology)</term>
<term>Lymphangiosarcoma (etiology)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (pathology)</term>
<term>Postthrombotic Syndrome (diagnosis)</term>
<term>Postthrombotic Syndrome (etiology)</term>
<term>Postthrombotic Syndrome (prevention & control)</term>
<term>Skin (pathology)</term>
<term>Skin Care</term>
<term>Skin Neoplasms (etiology)</term>
<term>Stockings, Compression</term>
<term>Venous Thrombosis (complications)</term>
<term>Venous Thrombosis (therapy)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anticoagulants</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Venous Thrombosis</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Postthrombotic Syndrome</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Erysipelas</term>
<term>Leg Dermatoses</term>
<term>Lymphangiosarcoma</term>
<term>Lymphedema</term>
<term>Postthrombotic Syndrome</term>
<term>Skin Neoplasms</term>
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<term>Leg Dermatoses</term>
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Postthrombotic Syndrome</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Venous Thrombosis</term>
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<front><div type="abstract" xml:lang="en">The incidence of the post-thrombotic syndrome (PTS) is increasing along with the incidence of deep vein thrombosis (DVT). The overall frequency of PTS ranges from 20 percent to 50 percent of DVT patients; severe PTS, which includes leg ulcers, occurs in a quarter of cases. Because of its severity and chronicity, PTS is associated with great morbidity and cost. Its diagnosis is primarily based on the presence of typical symptoms and signs, but objective evidence of venous valvular reflux can help to confirm the diagnosis. Because therapeutic options for PTS are extremely limited and results are often disappointing, prevention, recognition of clinical signs or complications, and early treatment remain the keys to reducing its morbidity. The prevention of DVT recurrence by anticoagulation and use of graduated compression stockings is likely to reduce the risk of PTS. There is no proven role for thrombolysis in preventing PTS.</div>
</front>
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<Month>09</Month>
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<Title>Dermatology online journal</Title>
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<ArticleTitle>The post-thrombotic syndrome - a condition to prevent.</ArticleTitle>
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<Abstract><AbstractText>The incidence of the post-thrombotic syndrome (PTS) is increasing along with the incidence of deep vein thrombosis (DVT). The overall frequency of PTS ranges from 20 percent to 50 percent of DVT patients; severe PTS, which includes leg ulcers, occurs in a quarter of cases. Because of its severity and chronicity, PTS is associated with great morbidity and cost. Its diagnosis is primarily based on the presence of typical symptoms and signs, but objective evidence of venous valvular reflux can help to confirm the diagnosis. Because therapeutic options for PTS are extremely limited and results are often disappointing, prevention, recognition of clinical signs or complications, and early treatment remain the keys to reducing its morbidity. The prevention of DVT recurrence by anticoagulation and use of graduated compression stockings is likely to reduce the risk of PTS. There is no proven role for thrombolysis in preventing PTS.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Pirard</LastName>
<ForeName>Delphine</ForeName>
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<MeshHeading><DescriptorName UI="D004886" MajorTopicYN="N">Erysipelas</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<MeshHeading><DescriptorName UI="D007868" MajorTopicYN="N">Leg Dermatoses</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<MeshHeading><DescriptorName UI="D008204" MajorTopicYN="N">Lymphangiosarcoma</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
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<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
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<MeshHeading><DescriptorName UI="D054070" MajorTopicYN="Y">Postthrombotic Syndrome</DescriptorName>
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<MeshHeading><DescriptorName UI="D012867" MajorTopicYN="N">Skin</DescriptorName>
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<MeshHeading><DescriptorName UI="D017592" MajorTopicYN="N">Skin Care</DescriptorName>
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<MeshHeading><DescriptorName UI="D012878" MajorTopicYN="N">Skin Neoplasms</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D053828" MajorTopicYN="N">Stockings, Compression</DescriptorName>
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<MeshHeading><DescriptorName UI="D020246" MajorTopicYN="N">Venous Thrombosis</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName>
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