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[Collagen-polyvinylpyrrolidone: a new therapeutic option for treatment of sequelae after radical mastectomy in women with breast cancer. Preliminary study].

Identifieur interne : 002808 ( PubMed/Corpus ); précédent : 002807; suivant : 002809

[Collagen-polyvinylpyrrolidone: a new therapeutic option for treatment of sequelae after radical mastectomy in women with breast cancer. Preliminary study].

Auteurs : Rafael Ruiz-Eng ; Alvaro Montiel-Jarquín ; Raúl De La Rosa-Pérez ; Aurelio L Pez-Colombo ; Eduardo G Mez-Conde ; Leticia Zamudio-Huerta

Source :

RBID : pubmed:21167096

English descriptors

Abstract

Approximately 30% of women who undergo mastectomy without reconstructive treatment due to breast cancer present sequelae. These include paresthesias, keloid healing, hypoesthesia, lymphedema and limitation of the function of the ipsilateral upper extremity. We undertook this study to present the results using collagen-polyvinylpyrrolidone (Clg- Pvp) as treatment for posmastectomy sequelae in women with breast cancer.

PubMed: 21167096

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pubmed:21167096

Le document en format XML

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<title xml:lang="en">[Collagen-polyvinylpyrrolidone: a new therapeutic option for treatment of sequelae after radical mastectomy in women with breast cancer. Preliminary study].</title>
<author>
<name sortKey="Ruiz Eng, Rafael" sort="Ruiz Eng, Rafael" uniqKey="Ruiz Eng R" first="Rafael" last="Ruiz-Eng">Rafael Ruiz-Eng</name>
<affiliation>
<nlm:affiliation>Departamento de Cirugía Plástica, Hospital General Regional 36, Instituto Mexicano del Seguro Social, Puebla, México. alvaro.montielj@imss.gob.mx</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Montiel Jarquin, Alvaro" sort="Montiel Jarquin, Alvaro" uniqKey="Montiel Jarquin A" first="Alvaro" last="Montiel-Jarquín">Alvaro Montiel-Jarquín</name>
</author>
<author>
<name sortKey="De La Rosa Perez, Raul" sort="De La Rosa Perez, Raul" uniqKey="De La Rosa Perez R" first="Raúl" last="De La Rosa-Pérez">Raúl De La Rosa-Pérez</name>
</author>
<author>
<name sortKey="L Pez Colombo, Aurelio" sort="L Pez Colombo, Aurelio" uniqKey="L Pez Colombo A" first="Aurelio" last="L Pez-Colombo">Aurelio L Pez-Colombo</name>
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<author>
<name sortKey="G Mez Conde, Eduardo" sort="G Mez Conde, Eduardo" uniqKey="G Mez Conde E" first="Eduardo" last="G Mez-Conde">Eduardo G Mez-Conde</name>
</author>
<author>
<name sortKey="Zamudio Huerta, Leticia" sort="Zamudio Huerta, Leticia" uniqKey="Zamudio Huerta L" first="Leticia" last="Zamudio-Huerta">Leticia Zamudio-Huerta</name>
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<title xml:lang="en">[Collagen-polyvinylpyrrolidone: a new therapeutic option for treatment of sequelae after radical mastectomy in women with breast cancer. Preliminary study].</title>
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<name sortKey="Ruiz Eng, Rafael" sort="Ruiz Eng, Rafael" uniqKey="Ruiz Eng R" first="Rafael" last="Ruiz-Eng">Rafael Ruiz-Eng</name>
<affiliation>
<nlm:affiliation>Departamento de Cirugía Plástica, Hospital General Regional 36, Instituto Mexicano del Seguro Social, Puebla, México. alvaro.montielj@imss.gob.mx</nlm:affiliation>
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<name sortKey="Montiel Jarquin, Alvaro" sort="Montiel Jarquin, Alvaro" uniqKey="Montiel Jarquin A" first="Alvaro" last="Montiel-Jarquín">Alvaro Montiel-Jarquín</name>
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<author>
<name sortKey="De La Rosa Perez, Raul" sort="De La Rosa Perez, Raul" uniqKey="De La Rosa Perez R" first="Raúl" last="De La Rosa-Pérez">Raúl De La Rosa-Pérez</name>
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<author>
<name sortKey="L Pez Colombo, Aurelio" sort="L Pez Colombo, Aurelio" uniqKey="L Pez Colombo A" first="Aurelio" last="L Pez-Colombo">Aurelio L Pez-Colombo</name>
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<name sortKey="G Mez Conde, Eduardo" sort="G Mez Conde, Eduardo" uniqKey="G Mez Conde E" first="Eduardo" last="G Mez-Conde">Eduardo G Mez-Conde</name>
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<name sortKey="Zamudio Huerta, Leticia" sort="Zamudio Huerta, Leticia" uniqKey="Zamudio Huerta L" first="Leticia" last="Zamudio-Huerta">Leticia Zamudio-Huerta</name>
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<series>
<title level="j">Cirugia y cirujanos</title>
<idno type="ISSN">0009-7411</idno>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Arm</term>
<term>Breast Neoplasms (surgery)</term>
<term>Cicatrix (etiology)</term>
<term>Cicatrix (prevention & control)</term>
<term>Collagen (administration & dosage)</term>
<term>Collagen (pharmacology)</term>
<term>Collagen (therapeutic use)</term>
<term>Dermatologic Agents (administration & dosage)</term>
<term>Dermatologic Agents (therapeutic use)</term>
<term>Esthetics</term>
<term>Female</term>
<term>Humans</term>
<term>Injections, Subcutaneous</term>
<term>Keloid (etiology)</term>
<term>Keloid (prevention & control)</term>
<term>Lymph Node Excision (adverse effects)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (prevention & control)</term>
<term>Mastectomy, Radical (adverse effects)</term>
<term>Middle Aged</term>
<term>Paresthesia (etiology)</term>
<term>Paresthesia (prevention & control)</term>
<term>Povidone (administration & dosage)</term>
<term>Povidone (pharmacology)</term>
<term>Povidone (therapeutic use)</term>
<term>Prospective Studies</term>
<term>Range of Motion, Articular</term>
<term>Wound Healing (drug effects)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en">
<term>Collagen</term>
<term>Dermatologic Agents</term>
<term>Povidone</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Lymph Node Excision</term>
<term>Mastectomy, Radical</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Wound Healing</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Cicatrix</term>
<term>Keloid</term>
<term>Lymphedema</term>
<term>Paresthesia</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en">
<term>Collagen</term>
<term>Povidone</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>Cicatrix</term>
<term>Keloid</term>
<term>Lymphedema</term>
<term>Paresthesia</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Collagen</term>
<term>Dermatologic Agents</term>
<term>Povidone</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Arm</term>
<term>Esthetics</term>
<term>Female</term>
<term>Humans</term>
<term>Injections, Subcutaneous</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Range of Motion, Articular</term>
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<front>
<div type="abstract" xml:lang="en">Approximately 30% of women who undergo mastectomy without reconstructive treatment due to breast cancer present sequelae. These include paresthesias, keloid healing, hypoesthesia, lymphedema and limitation of the function of the ipsilateral upper extremity. We undertook this study to present the results using collagen-polyvinylpyrrolidone (Clg- Pvp) as treatment for posmastectomy sequelae in women with breast cancer.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">21167096</PMID>
<DateCreated>
<Year>2010</Year>
<Month>12</Month>
<Day>20</Day>
</DateCreated>
<DateCompleted>
<Year>2011</Year>
<Month>05</Month>
<Day>19</Day>
</DateCompleted>
<DateRevised>
<Year>2015</Year>
<Month>03</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">0009-7411</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>78</Volume>
<Issue>4</Issue>
<PubDate>
<MedlineDate>2010 Jul-Aug</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Cirugia y cirujanos</Title>
<ISOAbbreviation>Cir Cir</ISOAbbreviation>
</Journal>
<ArticleTitle>[Collagen-polyvinylpyrrolidone: a new therapeutic option for treatment of sequelae after radical mastectomy in women with breast cancer. Preliminary study].</ArticleTitle>
<Pagination>
<MedlinePgn>310-4</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Approximately 30% of women who undergo mastectomy without reconstructive treatment due to breast cancer present sequelae. These include paresthesias, keloid healing, hypoesthesia, lymphedema and limitation of the function of the ipsilateral upper extremity. We undertook this study to present the results using collagen-polyvinylpyrrolidone (Clg- Pvp) as treatment for posmastectomy sequelae in women with breast cancer.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">We conducted a unicentric, longitudinal and prospective clinical trial between August 1, 2007 and July 31, 2008. Included variables were age, lymphedema, limitation of the function of the ipsilateral upper extremity, collapse of the wound, keloid healing, paresthesias, and appearance of the surgical area. The appearance of the surgical area (aesthetic aspect) was evaluated before and 6 months after treatment was initiated. Clg-Pvp was administered weekly for a 6-month period.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Seven women were included with a median age of 49 years (range: 40-72 years). One patient (14.28%) presented lymphedema, two patients (28.57%) presented collapse of the wound, two patients (28.57%) had keloid healing, three patients (42.85%) experienced paresthesias, five patients (71.4%) reported pain, and five patients (71.4%) reported limitation of the function of the ipsilateral upper extremity. At the completion of the treatment, aesthetic improvement was statistically significant (p = 0.0020, Mann-Whitney U test).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Clinical and aesthetic results are good after application of Clg-Pvp for treating sequelae in women with breast cancer who underwent mastectomy without reconstructive surgery.</AbstractText>
</Abstract>
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<LastName>Ruiz-Eng</LastName>
<ForeName>Rafael</ForeName>
<Initials>R</Initials>
<AffiliationInfo>
<Affiliation>Departamento de Cirugía Plástica, Hospital General Regional 36, Instituto Mexicano del Seguro Social, Puebla, México. alvaro.montielj@imss.gob.mx</Affiliation>
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<LastName>Montiel-Jarquín</LastName>
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<ForeName>Leticia</ForeName>
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<Language>spa</Language>
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<PublicationType UI="D016430">Clinical Trial</PublicationType>
<PublicationType UI="D004740">English Abstract</PublicationType>
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</PublicationTypeList>
<VernacularTitle>Colágeno-polivinilpirrolidona, nueva opción para tratar secuelas de la mastectomía radical en mujeres con cáncer mamario. Informe preliminar.</VernacularTitle>
</Article>
<MedlineJournalInfo>
<Country>Spain</Country>
<MedlineTA>Cir Cir</MedlineTA>
<NlmUniqueID>0372736</NlmUniqueID>
<ISSNLinking>0009-7411</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D003879">Dermatologic Agents</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C120488">collagen-PVP</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>9003-39-8</RegistryNumber>
<NameOfSubstance UI="D011205">Povidone</NameOfSubstance>
</Chemical>
<Chemical>
<RegistryNumber>9007-34-5</RegistryNumber>
<NameOfSubstance UI="D003094">Collagen</NameOfSubstance>
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<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<DescriptorName UI="D001132" MajorTopicYN="N">Arm</DescriptorName>
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<DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName>
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<DescriptorName UI="D003094" MajorTopicYN="N">Collagen</DescriptorName>
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