Massive localised lymphoedema: clinical presentation and MR imaging characteristics.
Identifieur interne : 002769 ( PubMed/Corpus ); précédent : 002768; suivant : 002770Massive localised lymphoedema: clinical presentation and MR imaging characteristics.
Auteurs : Monica Khanna ; Ali M. Naraghi ; David Salonen ; Rejpaul Bhumbra ; Brendan C. Dickson ; Mark J. Kransdorf ; Lawrence M. WhiteSource :
- Skeletal radiology [ 1432-2161 ] ; 2011.
English descriptors
- KwdEn :
- MESH :
- chemical : Gadolinium.
- diagnosis : Lymphedema.
- Female, Humans, Magnetic Resonance Imaging, Middle Aged, Obesity, Morbid.
Abstract
Three morbidly obese women were referred to us with suspected soft-tissue sarcomas. All lesions arose from the medial subcutaneous tissues of the thigh, and were shown to represent massive localised lymphoedema (MLL), a rare condition occurring in morbidly obese adults. MR imaging typically demonstrates a sharply demarcated, pedunculated mass consisting of fat partitioned by fibrous septae surrounded by a thickened dermis. There is oedema both within the mass and tracking along the subcutaneous septae in a "lace-like" fashion outwards from the pedicle, outlining large lobules of fat. Minimal enhancement is observed within the dermis of the lesion following intravenous gadolinium administration. Obesity is a growing problem that is likely to result in an increase in the prevalence of this condition; therefore, familiarity with the radiological appearance is important in establishing a correct diagnosis in this condition that may mimic a soft-tissue sarcoma.
DOI: 10.1007/s00256-010-1080-4
PubMed: 21249496
Links to Exploration step
pubmed:21249496Le document en format XML
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<author><name sortKey="Khanna, Monica" sort="Khanna, Monica" uniqKey="Khanna M" first="Monica" last="Khanna">Monica Khanna</name>
<affiliation><nlm:affiliation>Department of Clinical Imaging, Imperial College Healthcare NHS Trust, London, UK. monica.khanna@imperial.nhs.uk</nlm:affiliation>
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<author><name sortKey="Naraghi, Ali M" sort="Naraghi, Ali M" uniqKey="Naraghi A" first="Ali M" last="Naraghi">Ali M. Naraghi</name>
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<author><name sortKey="Salonen, David" sort="Salonen, David" uniqKey="Salonen D" first="David" last="Salonen">David Salonen</name>
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<author><name sortKey="Bhumbra, Rejpaul" sort="Bhumbra, Rejpaul" uniqKey="Bhumbra R" first="Rejpaul" last="Bhumbra">Rejpaul Bhumbra</name>
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<author><name sortKey="Dickson, Brendan C" sort="Dickson, Brendan C" uniqKey="Dickson B" first="Brendan C" last="Dickson">Brendan C. Dickson</name>
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<author><name sortKey="Kransdorf, Mark J" sort="Kransdorf, Mark J" uniqKey="Kransdorf M" first="Mark J" last="Kransdorf">Mark J. Kransdorf</name>
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<author><name sortKey="White, Lawrence M" sort="White, Lawrence M" uniqKey="White L" first="Lawrence M" last="White">Lawrence M. White</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Massive localised lymphoedema: clinical presentation and MR imaging characteristics.</title>
<author><name sortKey="Khanna, Monica" sort="Khanna, Monica" uniqKey="Khanna M" first="Monica" last="Khanna">Monica Khanna</name>
<affiliation><nlm:affiliation>Department of Clinical Imaging, Imperial College Healthcare NHS Trust, London, UK. monica.khanna@imperial.nhs.uk</nlm:affiliation>
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<author><name sortKey="Salonen, David" sort="Salonen, David" uniqKey="Salonen D" first="David" last="Salonen">David Salonen</name>
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<author><name sortKey="Bhumbra, Rejpaul" sort="Bhumbra, Rejpaul" uniqKey="Bhumbra R" first="Rejpaul" last="Bhumbra">Rejpaul Bhumbra</name>
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<series><title level="j">Skeletal radiology</title>
<idno type="eISSN">1432-2161</idno>
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<term>Gadolinium</term>
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<term>Magnetic Resonance Imaging</term>
<term>Middle Aged</term>
<term>Obesity, Morbid</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Gadolinium</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" xml:lang="en"><term>Female</term>
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<front><div type="abstract" xml:lang="en">Three morbidly obese women were referred to us with suspected soft-tissue sarcomas. All lesions arose from the medial subcutaneous tissues of the thigh, and were shown to represent massive localised lymphoedema (MLL), a rare condition occurring in morbidly obese adults. MR imaging typically demonstrates a sharply demarcated, pedunculated mass consisting of fat partitioned by fibrous septae surrounded by a thickened dermis. There is oedema both within the mass and tracking along the subcutaneous septae in a "lace-like" fashion outwards from the pedicle, outlining large lobules of fat. Minimal enhancement is observed within the dermis of the lesion following intravenous gadolinium administration. Obesity is a growing problem that is likely to result in an increase in the prevalence of this condition; therefore, familiarity with the radiological appearance is important in establishing a correct diagnosis in this condition that may mimic a soft-tissue sarcoma.</div>
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<Title>Skeletal radiology</Title>
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<ArticleTitle>Massive localised lymphoedema: clinical presentation and MR imaging characteristics.</ArticleTitle>
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<Abstract><AbstractText>Three morbidly obese women were referred to us with suspected soft-tissue sarcomas. All lesions arose from the medial subcutaneous tissues of the thigh, and were shown to represent massive localised lymphoedema (MLL), a rare condition occurring in morbidly obese adults. MR imaging typically demonstrates a sharply demarcated, pedunculated mass consisting of fat partitioned by fibrous septae surrounded by a thickened dermis. There is oedema both within the mass and tracking along the subcutaneous septae in a "lace-like" fashion outwards from the pedicle, outlining large lobules of fat. Minimal enhancement is observed within the dermis of the lesion following intravenous gadolinium administration. Obesity is a growing problem that is likely to result in an increase in the prevalence of this condition; therefore, familiarity with the radiological appearance is important in establishing a correct diagnosis in this condition that may mimic a soft-tissue sarcoma.</AbstractText>
</Abstract>
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