LymphedemaV1, PubMed, Corpus, bibRecord, 002547

Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.

Identifieur interne : 002547 ( PubMed/Corpus ); précédent : 002546; suivant : 002548

Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.

Auteurs : Prakash Senbagavalli ; Rajamanickam Anuradha ; Vadakkuppattu D. Ramanathan ; Vasanthapuram Kumaraswami ; Thomas B. Nutman ; Subash Babu

Source :

The American journal of tropical medicine and hygiene [ 1476-1645 ] ; 2011.

RBID : pubmed:21734131

English descriptors

KwdEn :
- Adolescent, Adult, Aged, Antigen-Antibody Complex (blood), Complement System Proteins (physiology), Elephantiasis, Filarial (immunology), Enzyme-Linked Immunosorbent Assay, Female, Granulocytes (immunology), Humans, Lymphocyte Activation, Male, Middle Aged, Young Adult.
MESH :
- chemical , blood : Antigen-Antibody Complex.
- chemical , physiology : Complement System Proteins.
- immunology : Elephantiasis, Filarial, Granulocytes.
- Adolescent, Adult, Aged, Enzyme-Linked Immunosorbent Assay, Female, Humans, Lymphocyte Activation, Male, Middle Aged, Young Adult.

Abstract

The presence of circulating immune complexes (CICs) is a characteristic feature of human lymphatic filariasis. However, the role of CICs in modulating granulocyte function and complement functional activity in filarial infection is unknown. The levels of CICs in association with complement activation in clinically asymptomatic, filarial-infected patients (INF); filarial-infected patients with overt lymphatic pathologic changes (CPDT); and uninfected controls (EN) were examined. Significantly increased levels of CICs and enhanced functional efficiency of the classical and mannose-binding lectin pathways of the complement system was observed in INF compared with CPDT and EN. Polyethylene glycol-precipitated CICs from INF and CPDT induced significantly increased granulocyte activation compared with those from EN, determined by the increased production of neutrophil granular proteins and a variety of pro-inflammatory cytokines. Thus, CIC-mediated enhanced granulocyte activation and modulation of complement function are important features of filarial infection and disease.

DOI: 10.4269/ajtmh.2011.11-0086
PubMed: 21734131

Links to Exploration step

pubmed:21734131

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.</title>
<author><name sortKey="Senbagavalli, Prakash" sort="Senbagavalli, Prakash" uniqKey="Senbagavalli P" first="Prakash" last="Senbagavalli">Prakash Senbagavalli</name>
<affiliation><nlm:affiliation>National Institutes of Health-International Center for Excellence in Research, Chennai, India. sen.valli@gmail.com</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Anuradha, Rajamanickam" sort="Anuradha, Rajamanickam" uniqKey="Anuradha R" first="Rajamanickam" last="Anuradha">Rajamanickam Anuradha</name>
</author>
<author><name sortKey="Ramanathan, Vadakkuppattu D" sort="Ramanathan, Vadakkuppattu D" uniqKey="Ramanathan V" first="Vadakkuppattu D" last="Ramanathan">Vadakkuppattu D. Ramanathan</name>
</author>
<author><name sortKey="Kumaraswami, Vasanthapuram" sort="Kumaraswami, Vasanthapuram" uniqKey="Kumaraswami V" first="Vasanthapuram" last="Kumaraswami">Vasanthapuram Kumaraswami</name>
</author>
<author><name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B" last="Nutman">Thomas B. Nutman</name>
</author>
<author><name sortKey="Babu, Subash" sort="Babu, Subash" uniqKey="Babu S" first="Subash" last="Babu">Subash Babu</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2011">2011</date>
<idno type="RBID">pubmed:21734131</idno>
<idno type="pmid">21734131</idno>
<idno type="doi">10.4269/ajtmh.2011.11-0086</idno>
<idno type="wicri:Area/PubMed/Corpus">002547</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002547</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.</title>
<author><name sortKey="Senbagavalli, Prakash" sort="Senbagavalli, Prakash" uniqKey="Senbagavalli P" first="Prakash" last="Senbagavalli">Prakash Senbagavalli</name>
<affiliation><nlm:affiliation>National Institutes of Health-International Center for Excellence in Research, Chennai, India. sen.valli@gmail.com</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Anuradha, Rajamanickam" sort="Anuradha, Rajamanickam" uniqKey="Anuradha R" first="Rajamanickam" last="Anuradha">Rajamanickam Anuradha</name>
</author>
<author><name sortKey="Ramanathan, Vadakkuppattu D" sort="Ramanathan, Vadakkuppattu D" uniqKey="Ramanathan V" first="Vadakkuppattu D" last="Ramanathan">Vadakkuppattu D. Ramanathan</name>
</author>
<author><name sortKey="Kumaraswami, Vasanthapuram" sort="Kumaraswami, Vasanthapuram" uniqKey="Kumaraswami V" first="Vasanthapuram" last="Kumaraswami">Vasanthapuram Kumaraswami</name>
</author>
<author><name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B" last="Nutman">Thomas B. Nutman</name>
</author>
<author><name sortKey="Babu, Subash" sort="Babu, Subash" uniqKey="Babu S" first="Subash" last="Babu">Subash Babu</name>
</author>
</analytic>
<series><title level="j">The American journal of tropical medicine and hygiene</title>
<idno type="eISSN">1476-1645</idno>
<imprint><date when="2011" type="published">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Antigen-Antibody Complex (blood)</term>
<term>Complement System Proteins (physiology)</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Female</term>
<term>Granulocytes (immunology)</term>
<term>Humans</term>
<term>Lymphocyte Activation</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antigen-Antibody Complex</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Complement System Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term>
<term>Granulocytes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Enzyme-Linked Immunosorbent Assay</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphocyte Activation</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The presence of circulating immune complexes (CICs) is a characteristic feature of human lymphatic filariasis. However, the role of CICs in modulating granulocyte function and complement functional activity in filarial infection is unknown. The levels of CICs in association with complement activation in clinically asymptomatic, filarial-infected patients (INF); filarial-infected patients with overt lymphatic pathologic changes (CPDT); and uninfected controls (EN) were examined. Significantly increased levels of CICs and enhanced functional efficiency of the classical and mannose-binding lectin pathways of the complement system was observed in INF compared with CPDT and EN. Polyethylene glycol-precipitated CICs from INF and CPDT induced significantly increased granulocyte activation compared with those from EN, determined by the increased production of neutrophil granular proteins and a variety of pro-inflammatory cytokines. Thus, CIC-mediated enhanced granulocyte activation and modulation of complement function are important features of filarial infection and disease.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">21734131</PMID>
<DateCreated><Year>2011</Year>
<Month>07</Month>
<Day>07</Day>
</DateCreated>
<DateCompleted><Year>2011</Year>
<Month>09</Month>
<Day>15</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>02</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1476-1645</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>85</Volume>
<Issue>1</Issue>
<PubDate><Year>2011</Year>
<Month>Jul</Month>
</PubDate>
</JournalIssue>
<Title>The American journal of tropical medicine and hygiene</Title>
<ISOAbbreviation>Am. J. Trop. Med. Hyg.</ISOAbbreviation>
</Journal>
<ArticleTitle>Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.</ArticleTitle>
<Pagination><MedlinePgn>89-96</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.4269/ajtmh.2011.11-0086</ELocationID>
<Abstract><AbstractText>The presence of circulating immune complexes (CICs) is a characteristic feature of human lymphatic filariasis. However, the role of CICs in modulating granulocyte function and complement functional activity in filarial infection is unknown. The levels of CICs in association with complement activation in clinically asymptomatic, filarial-infected patients (INF); filarial-infected patients with overt lymphatic pathologic changes (CPDT); and uninfected controls (EN) were examined. Significantly increased levels of CICs and enhanced functional efficiency of the classical and mannose-binding lectin pathways of the complement system was observed in INF compared with CPDT and EN. Polyethylene glycol-precipitated CICs from INF and CPDT induced significantly increased granulocyte activation compared with those from EN, determined by the increased production of neutrophil granular proteins and a variety of pro-inflammatory cytokines. Thus, CIC-mediated enhanced granulocyte activation and modulation of complement function are important features of filarial infection and disease.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Senbagavalli</LastName>
<ForeName>Prakash</ForeName>
<Initials>P</Initials>
<AffiliationInfo><Affiliation>National Institutes of Health-International Center for Excellence in Research, Chennai, India. sen.valli@gmail.com</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Anuradha</LastName>
<ForeName>Rajamanickam</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Ramanathan</LastName>
<ForeName>Vadakkuppattu D</ForeName>
<Initials>VD</Initials>
</Author>
<Author ValidYN="Y"><LastName>Kumaraswami</LastName>
<ForeName>Vasanthapuram</ForeName>
<Initials>V</Initials>
</Author>
<Author ValidYN="Y"><LastName>Nutman</LastName>
<ForeName>Thomas B</ForeName>
<Initials>TB</Initials>
</Author>
<Author ValidYN="Y"><LastName>Babu</LastName>
<ForeName>Subash</ForeName>
<Initials>S</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<GrantList CompleteYN="Y"><Grant><Agency>Intramural NIH HHS</Agency>
<Country>United States</Country>
</Grant>
</GrantList>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D052060">Research Support, N.I.H., Intramural</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Am J Trop Med Hyg</MedlineTA>
<NlmUniqueID>0370507</NlmUniqueID>
<ISSNLinking>0002-9637</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000936">Antigen-Antibody Complex</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>9007-36-7</RegistryNumber>
<NameOfSubstance UI="D003165">Complement System Proteins</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):230-3</RefSource>
<PMID Version="1">8337737</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Clin Exp Immunol. 1980 Mar;39(3):570-5</RefSource>
<PMID Version="1">7379329</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Indian J Pathol Microbiol. 1991 Apr;34(2):92-8</RefSource>
<PMID Version="1">1752648</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2009;3(4):e420</RefSource>
<PMID Version="1">19381284</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Microbes Infect. 1999 Oct;1(12):1015-22</RefSource>
<PMID Version="1">10617933</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 1981 Mar 12;304(11):653-6</RefSource>
<PMID Version="1">6450325</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Mol Immunol. 2004 Jun;41(4):449-56</RefSource>
<PMID Version="1">15163541</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Physiol Lung Cell Mol Physiol. 2009 Dec;297(6):L1091-102</RefSource>
<PMID Version="1">19801448</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Br J Haematol. 2005 Jun;129(6):830-8</RefSource>
<PMID Version="1">15953012</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 1995 Apr;171(4):997-1001</RefSource>
<PMID Version="1">7706830</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2003 Dec 15;171(12):6723-32</RefSource>
<PMID Version="1">14662876</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Annu Rev Microbiol. 1986;40:29-53</RefSource>
<PMID Version="1">2946261</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Scand J Clin Lab Invest Suppl. 1968;97:77-89</RefSource>
<PMID Version="1">4179068</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 2001 Jul;23(7):389-99</RefSource>
<PMID Version="1">11472558</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Arthritis Res Ther. 2006;8(3):R64</RefSource>
<PMID Version="1">16569263</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2007 Apr;101(3):205-13</RefSource>
<PMID Version="1">17362595</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Genes Immun. 2001 Aug;2(5):248-53</RefSource>
<PMID Version="1">11528516</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2009 Sep;77(9):3886-93</RefSource>
<PMID Version="1">19528206</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Int J Parasitol. 2010 Apr;40(5):527-32</RefSource>
<PMID Version="1">19874826</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Rheum Dis. 2003 Jan;62(1):37-42</RefSource>
<PMID Version="1">12480667</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2005 Oct;73(4):759-65</RefSource>
<PMID Version="1">16222022</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Exp Med. 1971 Sep 1;134(3):75-89</RefSource>
<PMID Version="1">19867384</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 1987 Jul;9(4):447-63</RefSource>
<PMID Version="1">3498141</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 1983 Mar;5(2):217-24</RefSource>
<PMID Version="1">6844030</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Annu Rev Med. 1981;32:13-28</RefSource>
<PMID Version="1">6452857</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Immunol Methods. 2001 Jul 1;253(1-2):13-21</RefSource>
<PMID Version="1">11384665</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2006 Aug;74(8):4409-17</RefSource>
<PMID Version="1">16861626</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Clin Lab Anal. 2007;21(2):114-8</RefSource>
<PMID Version="1">17385666</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Inflammation. 1981 Sep;5(3):213-22</RefSource>
<PMID Version="1">7028625</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Schweiz Med Wochenschr. 1985 Oct 12;115(41):1422-4</RefSource>
<PMID Version="1">2933806</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Immunol Cell Biol. 1987 Oct;65 Pt 5:365-70</RefSource>
<PMID Version="1">3325408</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Acta Trop. 1988 Sep;45(3):245-55</RefSource>
<PMID Version="1">2903626</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Clin Immunol. 1999 Dec;93(3):274-82</RefSource>
<PMID Version="1">10600339</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2010 Jan;82(1):115-20</RefSource>
<PMID Version="1">20065005</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2007 Apr 15;178(8):5116-23</RefSource>
<PMID Version="1">17404294</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitol Today. 2000 Dec;16(12):544-8</RefSource>
<PMID Version="1">11121854</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Trop Med Hyg. 1987 Jun;90(3):135-41</RefSource>
<PMID Version="1">3295279</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 1994 Oct;170(4):927-33</RefSource>
<PMID Version="1">7523538</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2000 May;68(5):3034-5</RefSource>
<PMID Version="1">10769010</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Microbes Infect. 2006 Aug;8(9-10):2414-23</RefSource>
<PMID Version="1">16839794</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Blood. 2008 Aug 15;112(4):1461-71</RefSource>
<PMID Version="1">18490516</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Kidney Int. 1979 Jul;16(1):9-14</RefSource>
<PMID Version="1">575177</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000936" MajorTopicYN="Y">Antigen-Antibody Complex</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003165" MajorTopicYN="N">Complement System Proteins</DescriptorName>
<QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004797" MajorTopicYN="N">Enzyme-Linked Immunosorbent Assay</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006098" MajorTopicYN="N">Granulocytes</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008213" MajorTopicYN="Y">Lymphocyte Activation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="NLM">PMC3122350</OtherID>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2011</Year>
<Month>7</Month>
<Day>8</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2011</Year>
<Month>7</Month>
<Day>8</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2011</Year>
<Month>9</Month>
<Day>16</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">21734131</ArticleId>
<ArticleId IdType="pii">85/1/89</ArticleId>
<ArticleId IdType="doi">10.4269/ajtmh.2011.11-0086</ArticleId>
<ArticleId IdType="pmc">PMC3122350</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002547 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 002547 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PubMed
   |étape=   Corpus
   |type=    RBID
   |clé=     pubmed:21734131
   |texte=   Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i   -Sk "pubmed:21734131" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le lymphœdème

Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.

Heightened measures of immune complex and complement function and immune complex-mediated granulocyte activation in human lymphatic filariasis.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki