[Sentinel lymph node biopsy and axillary reverse mapping: a tailoring axillary staging in breast cancer].
Identifieur interne : 002490 ( PubMed/Corpus ); précédent : 002489; suivant : 002491[Sentinel lymph node biopsy and axillary reverse mapping: a tailoring axillary staging in breast cancer].
Auteurs : P. Cusumano ; V. Bleret ; C. Nos ; R. Hustinx ; H. Lilet ; P. Gomez ; E. LifrangeSource :
- Revue medicale de Liege [ 0370-629X ]
English descriptors
- KwdEn :
- MESH :
- pathology : Breast Neoplasms, Lymph Nodes.
- Axilla, Female, Humans, Lymph Node Excision, Sentinel Lymph Node Biopsy.
Abstract
The status of the axillary lymph nodes is one of the most important prognostic factors in women with early stage breast cancer. Histologic examination of removed lymph nodes is the most accurate method for assessing spread of disease to these nodes. Axillary lymph node dissection (ALND) remains the standard approach for women who have clinically palpable axillary nodes. The benefits of ALND include its impact on disease control (axillary recurrence and survival), its prognostic value, and its role in treatment selection. However, the anatomic disruption caused by ALND may result in lymphedema, nerve injury, and shoulder dysfunction, which compromise functionality and quality of life. For patients who have clinically negative axillary lymph nodes, sentinel lymph node (SLN) biopsy offers a less morbid method to determine if there are positive nodes, in which case axillary node dissection would be necessary. Patients who are SLN-positive should undergo complete ALND. Axillary reverse mapping (ARM) is a recent improvement of ALND which, like the biopsy of the GS, would reduce morbidity.
PubMed: 21826973
Links to Exploration step
pubmed:21826973Le document en format XML
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<author><name sortKey="Cusumano, P" sort="Cusumano, P" uniqKey="Cusumano P" first="P" last="Cusumano">P. Cusumano</name>
<affiliation><nlm:affiliation>Service de Sénologie, CHU de Liège, Belgique. gcusumano@chu.ulg.ac.be</nlm:affiliation>
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<author><name sortKey="Bleret, V" sort="Bleret, V" uniqKey="Bleret V" first="V" last="Bleret">V. Bleret</name>
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<author><name sortKey="Nos, C" sort="Nos, C" uniqKey="Nos C" first="C" last="Nos">C. Nos</name>
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<author><name sortKey="Hustinx, R" sort="Hustinx, R" uniqKey="Hustinx R" first="R" last="Hustinx">R. Hustinx</name>
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<author><name sortKey="Lilet, H" sort="Lilet, H" uniqKey="Lilet H" first="H" last="Lilet">H. Lilet</name>
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<author><name sortKey="Gomez, P" sort="Gomez, P" uniqKey="Gomez P" first="P" last="Gomez">P. Gomez</name>
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<author><name sortKey="Lifrange, E" sort="Lifrange, E" uniqKey="Lifrange E" first="E" last="Lifrange">E. Lifrange</name>
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<term>Sentinel Lymph Node Biopsy</term>
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<term>Female</term>
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<front><div type="abstract" xml:lang="en">The status of the axillary lymph nodes is one of the most important prognostic factors in women with early stage breast cancer. Histologic examination of removed lymph nodes is the most accurate method for assessing spread of disease to these nodes. Axillary lymph node dissection (ALND) remains the standard approach for women who have clinically palpable axillary nodes. The benefits of ALND include its impact on disease control (axillary recurrence and survival), its prognostic value, and its role in treatment selection. However, the anatomic disruption caused by ALND may result in lymphedema, nerve injury, and shoulder dysfunction, which compromise functionality and quality of life. For patients who have clinically negative axillary lymph nodes, sentinel lymph node (SLN) biopsy offers a less morbid method to determine if there are positive nodes, in which case axillary node dissection would be necessary. Patients who are SLN-positive should undergo complete ALND. Axillary reverse mapping (ARM) is a recent improvement of ALND which, like the biopsy of the GS, would reduce morbidity.</div>
</front>
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<Title>Revue medicale de Liege</Title>
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<Abstract><AbstractText>The status of the axillary lymph nodes is one of the most important prognostic factors in women with early stage breast cancer. Histologic examination of removed lymph nodes is the most accurate method for assessing spread of disease to these nodes. Axillary lymph node dissection (ALND) remains the standard approach for women who have clinically palpable axillary nodes. The benefits of ALND include its impact on disease control (axillary recurrence and survival), its prognostic value, and its role in treatment selection. However, the anatomic disruption caused by ALND may result in lymphedema, nerve injury, and shoulder dysfunction, which compromise functionality and quality of life. For patients who have clinically negative axillary lymph nodes, sentinel lymph node (SLN) biopsy offers a less morbid method to determine if there are positive nodes, in which case axillary node dissection would be necessary. Patients who are SLN-positive should undergo complete ALND. Axillary reverse mapping (ARM) is a recent improvement of ALND which, like the biopsy of the GS, would reduce morbidity.</AbstractText>
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<VernacularTitle>Ganglion sentinelle et sentibras: pour un "staging" axillaire sur mesure.</VernacularTitle>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D001365" MajorTopicYN="N">Axilla</DescriptorName>
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<MeshHeading><DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName>
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