Quality of life and emotional distress in early stage and locally advanced cervical cancer patients: a prospective, longitudinal study.
Identifieur interne : 002411 ( PubMed/Corpus ); précédent : 002410; suivant : 002412Quality of life and emotional distress in early stage and locally advanced cervical cancer patients: a prospective, longitudinal study.
Auteurs : Gabriella Ferrandina ; Giovanna Mantegna ; Marco Petrillo ; Gilda Fuoco ; Laura Venditti ; Serena Terzano ; Cristina Moruzzi ; Domenica Lorusso ; Andrea Marcellusi ; Giovanni ScambiaSource :
- Gynecologic oncology [ 1095-6859 ] ; 2012.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Combined Modality Therapy, Female, Humans, Longitudinal Studies, Middle Aged, Neoplasm Staging, Prospective Studies, Quality of Life, Stress, Psychological (etiology), Stress, Psychological (psychology), Surveys and Questionnaires, Uterine Cervical Neoplasms (pathology), Uterine Cervical Neoplasms (psychology), Uterine Cervical Neoplasms (therapy).
- MESH :
- etiology : Stress, Psychological.
- pathology : Uterine Cervical Neoplasms.
- psychology : Stress, Psychological, Uterine Cervical Neoplasms.
- therapy : Uterine Cervical Neoplasms.
- Adult, Aged, Aged, 80 and over, Combined Modality Therapy, Female, Humans, Longitudinal Studies, Middle Aged, Neoplasm Staging, Prospective Studies, Quality of Life, Surveys and Questionnaires.
Abstract
This prospective, longitudinal study investigates QoL issues and emotional distress in early stage cervical cancer (ECC) patients undergoing radical surgery (RS) and in locally advanced cervical cancer (LACC) patients triaged to chemoradiation (CT/RT) followed by RS.
DOI: 10.1016/j.ygyno.2011.09.041
PubMed: 22035809
Links to Exploration step
pubmed:22035809Le document en format XML
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Fuoco</name></author><author><name sortKey="Venditti, Laura" sort="Venditti, Laura" uniqKey="Venditti L" first="Laura" last="Venditti">Laura Venditti</name></author><author><name sortKey="Terzano, Serena" sort="Terzano, Serena" uniqKey="Terzano S" first="Serena" last="Terzano">Serena Terzano</name></author><author><name sortKey="Moruzzi, Cristina" sort="Moruzzi, Cristina" uniqKey="Moruzzi C" first="Cristina" last="Moruzzi">Cristina Moruzzi</name></author><author><name sortKey="Lorusso, Domenica" sort="Lorusso, Domenica" uniqKey="Lorusso D" first="Domenica" last="Lorusso">Domenica Lorusso</name></author><author><name sortKey="Marcellusi, Andrea" sort="Marcellusi, Andrea" uniqKey="Marcellusi A" first="Andrea" last="Marcellusi">Andrea Marcellusi</name></author><author><name sortKey="Scambia, Giovanni" sort="Scambia, Giovanni" uniqKey="Scambia G" first="Giovanni" last="Scambia">Giovanni Scambia</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2012">2012</date><idno type="RBID">pubmed:22035809</idno><idno type="pmid">22035809</idno><idno type="doi">10.1016/j.ygyno.2011.09.041</idno><idno type="wicri:Area/PubMed/Corpus">002411</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">002411</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Quality of life and emotional distress in early stage and locally advanced cervical cancer patients: a prospective, longitudinal study.</title><author><name sortKey="Ferrandina, Gabriella" sort="Ferrandina, Gabriella" uniqKey="Ferrandina G" first="Gabriella" last="Ferrandina">Gabriella Ferrandina</name><affiliation><nlm:affiliation>Gynecologic Oncology Unit, Department of Oncology, Catholic University, Campobasso, Italy. gabriella.ferrandina@libero.it</nlm:affiliation></affiliation></author><author><name sortKey="Mantegna, Giovanna" sort="Mantegna, Giovanna" uniqKey="Mantegna G" first="Giovanna" last="Mantegna">Giovanna Mantegna</name></author><author><name sortKey="Petrillo, Marco" sort="Petrillo, Marco" uniqKey="Petrillo M" first="Marco" last="Petrillo">Marco Petrillo</name></author><author><name sortKey="Fuoco, Gilda" sort="Fuoco, Gilda" uniqKey="Fuoco G" first="Gilda" last="Fuoco">Gilda Fuoco</name></author><author><name sortKey="Venditti, Laura" sort="Venditti, Laura" uniqKey="Venditti L" first="Laura" last="Venditti">Laura Venditti</name></author><author><name sortKey="Terzano, Serena" sort="Terzano, Serena" uniqKey="Terzano S" first="Serena" last="Terzano">Serena Terzano</name></author><author><name sortKey="Moruzzi, Cristina" sort="Moruzzi, Cristina" uniqKey="Moruzzi C" first="Cristina" last="Moruzzi">Cristina Moruzzi</name></author><author><name sortKey="Lorusso, Domenica" sort="Lorusso, Domenica" uniqKey="Lorusso D" first="Domenica" last="Lorusso">Domenica Lorusso</name></author><author><name sortKey="Marcellusi, Andrea" sort="Marcellusi, Andrea" uniqKey="Marcellusi A" first="Andrea" last="Marcellusi">Andrea Marcellusi</name></author><author><name sortKey="Scambia, Giovanni" sort="Scambia, Giovanni" uniqKey="Scambia G" first="Giovanni" last="Scambia">Giovanni Scambia</name></author></analytic><series><title level="j">Gynecologic oncology</title><idno type="eISSN">1095-6859</idno><imprint><date when="2012" type="published">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Combined Modality Therapy</term><term>Female</term><term>Humans</term><term>Longitudinal Studies</term><term>Middle Aged</term><term>Neoplasm Staging</term><term>Prospective Studies</term><term>Quality of Life</term><term>Stress, Psychological (etiology)</term><term>Stress, Psychological (psychology)</term><term>Surveys and Questionnaires</term><term>Uterine Cervical Neoplasms (pathology)</term><term>Uterine Cervical Neoplasms (psychology)</term><term>Uterine Cervical Neoplasms (therapy)</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Stress, Psychological</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Uterine Cervical Neoplasms</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Stress, Psychological</term><term>Uterine Cervical Neoplasms</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Uterine Cervical Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Combined Modality Therapy</term><term>Female</term><term>Humans</term><term>Longitudinal Studies</term><term>Middle Aged</term><term>Neoplasm Staging</term><term>Prospective Studies</term><term>Quality of Life</term><term>Surveys and Questionnaires</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This prospective, longitudinal study investigates QoL issues and emotional distress in early stage cervical cancer (ECC) patients undergoing radical surgery (RS) and in locally advanced cervical cancer (LACC) patients triaged to chemoradiation (CT/RT) followed by RS.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22035809</PMID><DateCreated><Year>2012</Year><Month>02</Month><Day>13</Day></DateCreated><DateCompleted><Year>2012</Year><Month>04</Month><Day>30</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1095-6859</ISSN><JournalIssue CitedMedium="Internet"><Volume>124</Volume><Issue>3</Issue><PubDate><Year>2012</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Gynecologic oncology</Title><ISOAbbreviation>Gynecol. Oncol.</ISOAbbreviation></Journal><ArticleTitle>Quality of life and emotional distress in early stage and locally advanced cervical cancer patients: a prospective, longitudinal study.</ArticleTitle><Pagination><MedlinePgn>389-94</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.ygyno.2011.09.041</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">This prospective, longitudinal study investigates QoL issues and emotional distress in early stage cervical cancer (ECC) patients undergoing radical surgery (RS) and in locally advanced cervical cancer (LACC) patients triaged to chemoradiation (CT/RT) followed by RS.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The Global Health Status scale of EORTC QLQ-C30 (GHS), the EORTC QLQ-CX24 (CX24) and the Hospital Anxiety and Depression Scale (HADS) questionnaire were administered at baseline, and after 3, 6, and 12 months from surgery. For LACC patients QoL assessment was also performed after CT/RT. Statistical analysis was performed by the ANOVA for repeated measures and the Between Subject test.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">In ECC and LACC patients, the GHS scores improved over time (5.5% difference in mean scores compared to baseline in ECC, and 7.0% difference in mean score compared to baseline in LACC patients). An early worsening of lymphedema scores was documented in ECC cases (14.6% difference in mean values compared to baseline, p value=0.001), and in LACC patients (difference up to 28.3% of mean values, value=0.0001). Menopausal symptoms persistently worsened over time reaching >15% difference of mean values compared to baseline in both groups. Sexual activity scores markedly improved both in ECC and LACC patients (difference of mean score values compared to baseline was 16.5% in ECC, and 6.7% in LACC patients). Both ECC and LACC patients experienced an improvement of anxiety scores.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Lymphedema and menopausal symptoms were the most disabling treatment-related sequelae; the amount of QoL issues and their multifaceted aspects require the cooperation of multidisciplinary teams.</AbstractText><CopyrightInformation>Copyright © 2011 Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ferrandina</LastName><ForeName>Gabriella</ForeName><Initials>G</Initials><AffiliationInfo><Affiliation>Gynecologic Oncology Unit, Department of Oncology, Catholic University, Campobasso, Italy. gabriella.ferrandina@libero.it</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mantegna</LastName><ForeName>Giovanna</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Petrillo</LastName><ForeName>Marco</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Fuoco</LastName><ForeName>Gilda</ForeName><Initials>G</Initials></Author><Author ValidYN="Y"><LastName>Venditti</LastName><ForeName>Laura</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Terzano</LastName><ForeName>Serena</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Moruzzi</LastName><ForeName>Cristina</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Lorusso</LastName><ForeName>Domenica</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Marcellusi</LastName><ForeName>Andrea</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Scambia</LastName><ForeName>Giovanni</ForeName><Initials>G</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>10</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Gynecol Oncol</MedlineTA><NlmUniqueID>0365304</NlmUniqueID><ISSNLinking>0090-8258</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Gynecol Oncol. 2012 Jul;126(1):167; author reply 167-8</RefSource><PMID Version="1">22433463</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003131" MajorTopicYN="N">Combined Modality Therapy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008137" MajorTopicYN="N">Longitudinal Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009367" MajorTopicYN="N">Neoplasm Staging</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="N">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013315" MajorTopicYN="N">Stress, Psychological</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002583" MajorTopicYN="N">Uterine Cervical Neoplasms</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="N">therapy</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2011</Year><Month>09</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2011</Year><Month>09</Month><Day>24</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2011</Year><Month>09</Month><Day>29</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>11</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>11</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2012</Year><Month>5</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22035809</ArticleId><ArticleId IdType="pii">S0090-8258(11)00811-0</ArticleId><ArticleId IdType="doi">10.1016/j.ygyno.2011.09.041</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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