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Depression is associated with some patient-perceived cosmetic changes, but not with radiotherapy-induced late toxicity, in long-term breast cancer survivors.

Identifieur interne : 002279 ( PubMed/Corpus ); précédent : 002278; suivant : 002280

Depression is associated with some patient-perceived cosmetic changes, but not with radiotherapy-induced late toxicity, in long-term breast cancer survivors.

Auteurs : Paul Brunault ; Isabelle Suzanne ; Magdalena Trzepidur-Edom ; Pascal Garaud ; Gilles Calais ; Alain Toledano ; Vincent Camus

Source :

RBID : pubmed:22315168

English descriptors

Abstract

Although depression is prevalent in long-term breast cancer survivors (LTBCS; ≥ 5 years since diagnosis), it is underdiagnosed and undertreated. A better understanding of factors associated with depression could improve depression screening, treatment, and prevention in this population. Our study aimed to assess the link between patient and doctor ratings of breast cosmetic outcomes, late radiotherapy toxicity, and depression in LTBCS.

DOI: 10.1002/pon.3038
PubMed: 22315168

Links to Exploration step

pubmed:22315168

Le document en format XML

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<title xml:lang="en">Depression is associated with some patient-perceived cosmetic changes, but not with radiotherapy-induced late toxicity, in long-term breast cancer survivors.</title>
<author>
<name sortKey="Brunault, Paul" sort="Brunault, Paul" uniqKey="Brunault P" first="Paul" last="Brunault">Paul Brunault</name>
<affiliation>
<nlm:affiliation>CHRU de Tours, Tours, France. paul.brunault@gmail.com</nlm:affiliation>
</affiliation>
</author>
<author>
<name sortKey="Suzanne, Isabelle" sort="Suzanne, Isabelle" uniqKey="Suzanne I" first="Isabelle" last="Suzanne">Isabelle Suzanne</name>
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<author>
<name sortKey="Trzepidur Edom, Magdalena" sort="Trzepidur Edom, Magdalena" uniqKey="Trzepidur Edom M" first="Magdalena" last="Trzepidur-Edom">Magdalena Trzepidur-Edom</name>
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<author>
<name sortKey="Garaud, Pascal" sort="Garaud, Pascal" uniqKey="Garaud P" first="Pascal" last="Garaud">Pascal Garaud</name>
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<author>
<name sortKey="Calais, Gilles" sort="Calais, Gilles" uniqKey="Calais G" first="Gilles" last="Calais">Gilles Calais</name>
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<name sortKey="Toledano, Alain" sort="Toledano, Alain" uniqKey="Toledano A" first="Alain" last="Toledano">Alain Toledano</name>
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<name sortKey="Camus, Vincent" sort="Camus, Vincent" uniqKey="Camus V" first="Vincent" last="Camus">Vincent Camus</name>
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<title xml:lang="en">Depression is associated with some patient-perceived cosmetic changes, but not with radiotherapy-induced late toxicity, in long-term breast cancer survivors.</title>
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<name sortKey="Trzepidur Edom, Magdalena" sort="Trzepidur Edom, Magdalena" uniqKey="Trzepidur Edom M" first="Magdalena" last="Trzepidur-Edom">Magdalena Trzepidur-Edom</name>
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<name sortKey="Calais, Gilles" sort="Calais, Gilles" uniqKey="Calais G" first="Gilles" last="Calais">Gilles Calais</name>
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<name sortKey="Toledano, Alain" sort="Toledano, Alain" uniqKey="Toledano A" first="Alain" last="Toledano">Alain Toledano</name>
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<title level="j">Psycho-oncology</title>
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<term>Adult</term>
<term>Aged</term>
<term>Body Image (psychology)</term>
<term>Breast Neoplasms (psychology)</term>
<term>Breast Neoplasms (radiotherapy)</term>
<term>Cicatrix (psychology)</term>
<term>Cohort Studies</term>
<term>Depressive Disorder (psychology)</term>
<term>Edema (psychology)</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphedema (psychology)</term>
<term>Middle Aged</term>
<term>Radiation Injuries (psychology)</term>
<term>Surveys and Questionnaires</term>
<term>Survivors (psychology)</term>
<term>Telangiectasis (psychology)</term>
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<term>Body Image</term>
<term>Breast Neoplasms</term>
<term>Cicatrix</term>
<term>Depressive Disorder</term>
<term>Edema</term>
<term>Lymphedema</term>
<term>Radiation Injuries</term>
<term>Survivors</term>
<term>Telangiectasis</term>
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<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en">
<term>Breast Neoplasms</term>
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<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Cohort Studies</term>
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<div type="abstract" xml:lang="en">Although depression is prevalent in long-term breast cancer survivors (LTBCS; ≥ 5 years since diagnosis), it is underdiagnosed and undertreated. A better understanding of factors associated with depression could improve depression screening, treatment, and prevention in this population. Our study aimed to assess the link between patient and doctor ratings of breast cosmetic outcomes, late radiotherapy toxicity, and depression in LTBCS.</div>
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<Month>03</Month>
<Day>04</Day>
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<DateCompleted>
<Year>2013</Year>
<Month>08</Month>
<Day>19</Day>
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<Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
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<ISSN IssnType="Electronic">1099-1611</ISSN>
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<Volume>22</Volume>
<Issue>3</Issue>
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<Year>2013</Year>
<Month>Mar</Month>
</PubDate>
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<Title>Psycho-oncology</Title>
<ISOAbbreviation>Psychooncology</ISOAbbreviation>
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<ArticleTitle>Depression is associated with some patient-perceived cosmetic changes, but not with radiotherapy-induced late toxicity, in long-term breast cancer survivors.</ArticleTitle>
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<MedlinePgn>590-7</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1002/pon.3038</ELocationID>
<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">Although depression is prevalent in long-term breast cancer survivors (LTBCS; ≥ 5 years since diagnosis), it is underdiagnosed and undertreated. A better understanding of factors associated with depression could improve depression screening, treatment, and prevention in this population. Our study aimed to assess the link between patient and doctor ratings of breast cosmetic outcomes, late radiotherapy toxicity, and depression in LTBCS.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">In all, 214 patients recruited from the ARCOSEIN study were assessed for late radiotherapy toxicity (by using the LENT-SOMA scale) and patient and doctor ratings of breast cosmetic outcomes (mean = 6.7 years since the end of treatment). We reassessed 120 of these patients for depression (HAD) during a second wave of long-term assessment (mean = 8.1 years since the end of treatment). We used univariate analyses and polytomous logistic regression analyses to predict the HAD depression, which was defined as follows: normal, 0-7 points; and significant depression, ≥ 8 points (8-10 points, possible depression; ≥ 11 points, probable depression).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The mean HAD depression score was 4.5 ± 3.6. 19. 2% of our population had significant depression, 6.7% with probable depression, and 12.5% with possible depression. Significant depression was not associated with late radiotherapy toxicity or initial cancer-related variables. Patients with probable depression reported worse cosmetic outcomes than nondepressed patients in terms of perceived breast largeness (p = 0.04), breast deformation (p = 0.02), and changes in skin pigmentation (p = 0.03).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">In LTBCS, depression seems to be more strongly associated with changes in some patients' perceived breast cosmetic outcome than late treatment toxicity or initial cancer-related variables.</AbstractText>
<CopyrightInformation>Copyright © 2012 John Wiley & Sons, Ltd.</CopyrightInformation>
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