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Immediate breast reconstruction and lymphedema incidence.

Identifieur interne : 002145 ( PubMed/Corpus ); précédent : 002144; suivant : 002146

Immediate breast reconstruction and lymphedema incidence.

Auteurs : Melissa A. Crosby ; Annika Card ; Jun Liu ; Wayne A. Lindstrom ; David W. Chang

Source :

RBID : pubmed:22544109

English descriptors

Abstract

As breast cancer survivorship increases, more women are being affected by treatment sequelae, including lymphedema. The purpose of this study was to evaluate lymphedema incidence among immediate breast reconstruction patients and determine what factors are associated with lymphedema, including reconstruction method.

DOI: 10.1097/PRS.0b013e31824a2ab1
PubMed: 22544109

Links to Exploration step

pubmed:22544109

Le document en format XML

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<name sortKey="Crosby, Melissa A" sort="Crosby, Melissa A" uniqKey="Crosby M" first="Melissa A" last="Crosby">Melissa A. Crosby</name>
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<nlm:affiliation>Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center. Houston, Texas 77230-1402, USA. macrosby@mdanderson.org</nlm:affiliation>
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<name sortKey="Card, Annika" sort="Card, Annika" uniqKey="Card A" first="Annika" last="Card">Annika Card</name>
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<name sortKey="Liu, Jun" sort="Liu, Jun" uniqKey="Liu J" first="Jun" last="Liu">Jun Liu</name>
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<name sortKey="Lindstrom, Wayne A" sort="Lindstrom, Wayne A" uniqKey="Lindstrom W" first="Wayne A" last="Lindstrom">Wayne A. Lindstrom</name>
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<name sortKey="Chang, David W" sort="Chang, David W" uniqKey="Chang D" first="David W" last="Chang">David W. Chang</name>
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<title xml:lang="en">Immediate breast reconstruction and lymphedema incidence.</title>
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<name sortKey="Crosby, Melissa A" sort="Crosby, Melissa A" uniqKey="Crosby M" first="Melissa A" last="Crosby">Melissa A. Crosby</name>
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<nlm:affiliation>Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center. Houston, Texas 77230-1402, USA. macrosby@mdanderson.org</nlm:affiliation>
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<name sortKey="Card, Annika" sort="Card, Annika" uniqKey="Card A" first="Annika" last="Card">Annika Card</name>
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<name sortKey="Liu, Jun" sort="Liu, Jun" uniqKey="Liu J" first="Jun" last="Liu">Jun Liu</name>
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<name sortKey="Lindstrom, Wayne A" sort="Lindstrom, Wayne A" uniqKey="Lindstrom W" first="Wayne A" last="Lindstrom">Wayne A. Lindstrom</name>
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<name sortKey="Chang, David W" sort="Chang, David W" uniqKey="Chang D" first="David W" last="Chang">David W. Chang</name>
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<title level="j">Plastic and reconstructive surgery</title>
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<term>Adult</term>
<term>Aged</term>
<term>Body Mass Index</term>
<term>Breast Neoplasms (pathology)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Lymph Node Excision</term>
<term>Lymph Nodes (pathology)</term>
<term>Lymphatic Metastasis</term>
<term>Lymphedema (epidemiology)</term>
<term>Lymphedema (etiology)</term>
<term>Mammaplasty (adverse effects)</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en">
<term>Mammaplasty</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Breast Neoplasms</term>
<term>Lymph Nodes</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Body Mass Index</term>
<term>Female</term>
<term>Humans</term>
<term>Incidence</term>
<term>Lymph Node Excision</term>
<term>Lymphatic Metastasis</term>
<term>Middle Aged</term>
<term>Retrospective Studies</term>
<term>Young Adult</term>
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<div type="abstract" xml:lang="en">As breast cancer survivorship increases, more women are being affected by treatment sequelae, including lymphedema. The purpose of this study was to evaluate lymphedema incidence among immediate breast reconstruction patients and determine what factors are associated with lymphedema, including reconstruction method.</div>
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<Day>30</Day>
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<DateCompleted>
<Year>2012</Year>
<Month>06</Month>
<Day>25</Day>
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<Year>2015</Year>
<Month>06</Month>
<Day>24</Day>
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<ISSN IssnType="Electronic">1529-4242</ISSN>
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<Volume>129</Volume>
<Issue>5</Issue>
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<Year>2012</Year>
<Month>May</Month>
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</JournalIssue>
<Title>Plastic and reconstructive surgery</Title>
<ISOAbbreviation>Plast. Reconstr. Surg.</ISOAbbreviation>
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<ArticleTitle>Immediate breast reconstruction and lymphedema incidence.</ArticleTitle>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">As breast cancer survivorship increases, more women are being affected by treatment sequelae, including lymphedema. The purpose of this study was to evaluate lymphedema incidence among immediate breast reconstruction patients and determine what factors are associated with lymphedema, including reconstruction method.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The authors reviewed the outcomes of all consecutive patients who underwent immediate postmastectomy breast reconstruction at their institution between 2001 and 2006. Patient, treatment, and outcome characteristics were compared among reconstruction types: expander and implant, latissimus dorsi myocutaneous flap and implant, and autologous flap alone. Regression models were used to determine whether patient and treatment characteristics were associated with lymphedema development.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">This study included 1117 patients (1499 breasts), with a mean follow-up of 56 months. Axillary interventions (p < 0.001), high numbers of positive lymph nodes (p = 0.004), postoperative radiation therapy (p = 0.007), and body mass index of 25 kg/m or greater (p = 0.010) were strong predictors of increased lymphedema incidence. After excluding prophylactic mastectomy and reconstruction group changes, the authors found that the mean lymphedema incidence was 4.0 percent (of 1013 breasts). Reconstruction type had no significant effect on incidence of or time to lymphedema, and no interaction was found between axillary intervention and reconstruction type (p = 0.799).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The incidence of lymphedema after immediate reconstruction was associated with high body mass index, axillary interventions, and high numbers of positive lymph nodes. The reconstructive method did not appear to affect lymphedema incidence or timing.</AbstractText>
<AbstractText Label="CLINICAL QUESTION/LEVEL OF EVIDENCE" NlmCategory="METHODS">Risk, III.</AbstractText>
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<Affiliation>Department of Plastic Surgery, The University of Texas M. D. Anderson Cancer Center. Houston, Texas 77230-1402, USA. macrosby@mdanderson.org</Affiliation>
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<RefSource>Plast Reconstr Surg. 2012 Nov;130(5):749e-750e; author reply 750e-751e</RefSource>
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