Penile and scrotal lymphedema as an unusual presentation of Crohn's disease: case report and review of the literature.
Identifieur interne : 002047 ( PubMed/Corpus ); précédent : 002046; suivant : 002048Penile and scrotal lymphedema as an unusual presentation of Crohn's disease: case report and review of the literature.
Auteurs : W. Reitsma ; M J Wiegman ; R J DamstraSource :
- Lymphology [ 0024-7766 ] ; 2012.
English descriptors
- KwdEn :
- Adult, Crohn Disease (complications), Crohn Disease (diagnosis), Crohn Disease (therapy), Humans, Lymphedema (etiology), Lymphedema (pathology), Lymphedema (therapy), Magnetic Resonance Imaging, Male, Penile Diseases (etiology), Penile Diseases (pathology), Penile Diseases (therapy), Rectal Fistula (etiology), Scrotum (pathology).
- MESH :
- complications : Crohn Disease.
- diagnosis : Crohn Disease.
- etiology : Lymphedema, Penile Diseases, Rectal Fistula.
- pathology : Lymphedema, Penile Diseases, Scrotum.
- therapy : Crohn Disease, Lymphedema, Penile Diseases.
- Adult, Humans, Magnetic Resonance Imaging, Male.
Abstract
Crohn's disease is an inflammatory intestinal disease that primarily causes abdominal pain and diarrhea. We report a male patient who presented with penile and scrotal lymphedema and inguinal fistulas as the first manifestations of Crohn's disease. Extraintestinal or metastatic Crohn's disease initially presenting as genital lymphedema with fistula formation is rare. Skin lesions in extraintestinal Crohn's disease typically show non-caseating, sarcoidal granulomas with numerous foreign body- and Langhans-type multinucleated giant cells, which are separated from intestinal involvement by normal skin. Treatment options are limited and include multi-immunosuppressant medications.
PubMed: 22768472
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pubmed:22768472Le document en format XML
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<author><name sortKey="Reitsma, W" sort="Reitsma, W" uniqKey="Reitsma W" first="W" last="Reitsma">W. Reitsma</name>
<affiliation><nlm:affiliation>Department of Obstetrics & Gynecology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. w.reitsma@umcg.nl</nlm:affiliation>
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<author><name sortKey="Wiegman, M J" sort="Wiegman, M J" uniqKey="Wiegman M" first="M J" last="Wiegman">M J Wiegman</name>
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<author><name sortKey="Damstra, R J" sort="Damstra, R J" uniqKey="Damstra R" first="R J" last="Damstra">R J Damstra</name>
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<author><name sortKey="Wiegman, M J" sort="Wiegman, M J" uniqKey="Wiegman M" first="M J" last="Wiegman">M J Wiegman</name>
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<series><title level="j">Lymphology</title>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Crohn Disease (complications)</term>
<term>Crohn Disease (diagnosis)</term>
<term>Crohn Disease (therapy)</term>
<term>Humans</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphedema (therapy)</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Penile Diseases (etiology)</term>
<term>Penile Diseases (pathology)</term>
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<term>Rectal Fistula (etiology)</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Crohn Disease</term>
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<term>Penile Diseases</term>
<term>Rectal Fistula</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphedema</term>
<term>Penile Diseases</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Crohn Disease</term>
<term>Lymphedema</term>
<term>Penile Diseases</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
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<front><div type="abstract" xml:lang="en">Crohn's disease is an inflammatory intestinal disease that primarily causes abdominal pain and diarrhea. We report a male patient who presented with penile and scrotal lymphedema and inguinal fistulas as the first manifestations of Crohn's disease. Extraintestinal or metastatic Crohn's disease initially presenting as genital lymphedema with fistula formation is rare. Skin lesions in extraintestinal Crohn's disease typically show non-caseating, sarcoidal granulomas with numerous foreign body- and Langhans-type multinucleated giant cells, which are separated from intestinal involvement by normal skin. Treatment options are limited and include multi-immunosuppressant medications.</div>
</front>
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<Title>Lymphology</Title>
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<Abstract><AbstractText>Crohn's disease is an inflammatory intestinal disease that primarily causes abdominal pain and diarrhea. We report a male patient who presented with penile and scrotal lymphedema and inguinal fistulas as the first manifestations of Crohn's disease. Extraintestinal or metastatic Crohn's disease initially presenting as genital lymphedema with fistula formation is rare. Skin lesions in extraintestinal Crohn's disease typically show non-caseating, sarcoidal granulomas with numerous foreign body- and Langhans-type multinucleated giant cells, which are separated from intestinal involvement by normal skin. Treatment options are limited and include multi-immunosuppressant medications.</AbstractText>
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