Lymphoscintigraphy for differential diagnosis of peripheral edema: diagnostic yield of different scintigraphic patterns.
Identifieur interne : 001F06 ( PubMed/Corpus ); précédent : 001F05; suivant : 001F07Lymphoscintigraphy for differential diagnosis of peripheral edema: diagnostic yield of different scintigraphic patterns.
Auteurs : J R Infante ; L. García ; P. Laguna ; C. Durán ; J I Rayo ; J. Serrano ; M L Domínguez ; R. SánchezSource :
- Revista espanola de medicina nuclear e imagen molecular [ 2253-8070 ] ; 2012.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Axilla (diagnostic imaging), Cardiovascular Diseases (complications), Cardiovascular Diseases (diagnostic imaging), Child, Child, Preschool, Diagnosis, Differential, Edema (diagnostic imaging), Edema (etiology), Female, Groin (diagnostic imaging), Humans, Infant, Leg Injuries (complications), Leg Injuries (diagnostic imaging), Lymphedema (diagnostic imaging), Lymphedema (etiology), Lymphoscintigraphy, Male, Middle Aged, Neoplasms (complications), Neoplasms (diagnostic imaging), Postoperative Complications (diagnostic imaging), Postoperative Complications (etiology), Prospective Studies, Radiopharmaceuticals, Sensitivity and Specificity, Technetium Tc 99m Aggregated Albumin, Thrombophlebitis (complications), Thrombophlebitis (diagnostic imaging), Young Adult.
- MESH :
- chemical : Radiopharmaceuticals, Technetium Tc 99m Aggregated Albumin.
- complications : Cardiovascular Diseases, Leg Injuries, Neoplasms, Thrombophlebitis.
- diagnostic imaging : Axilla, Cardiovascular Diseases, Edema, Groin, Leg Injuries, Lymphedema, Neoplasms, Postoperative Complications, Thrombophlebitis.
- etiology : Edema, Lymphedema, Postoperative Complications.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Diagnosis, Differential, Female, Humans, Infant, Lymphoscintigraphy, Male, Middle Aged, Prospective Studies, Sensitivity and Specificity, Young Adult.
Abstract
Edema of the limbs is a common reason for medical consultation, for which the lymphoscintigraphy is considered to be a reliable method for its differential diagnosis.
DOI: 10.1016/j.remn.2011.11.011
PubMed: 23067524
Links to Exploration step
pubmed:23067524Le document en format XML
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<author><name sortKey="Infante, J R" sort="Infante, J R" uniqKey="Infante J" first="J R" last="Infante">J R Infante</name>
<affiliation><nlm:affiliation>Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Badajoz, Badajoz, Spain. infantetorre@yahoo.com</nlm:affiliation>
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<author><name sortKey="Garcia, L" sort="Garcia, L" uniqKey="Garcia L" first="L" last="García">L. García</name>
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<author><name sortKey="Laguna, P" sort="Laguna, P" uniqKey="Laguna P" first="P" last="Laguna">P. Laguna</name>
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<author><name sortKey="Duran, C" sort="Duran, C" uniqKey="Duran C" first="C" last="Durán">C. Durán</name>
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<author><name sortKey="Rayo, J I" sort="Rayo, J I" uniqKey="Rayo J" first="J I" last="Rayo">J I Rayo</name>
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<author><name sortKey="Serrano, J" sort="Serrano, J" uniqKey="Serrano J" first="J" last="Serrano">J. Serrano</name>
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<author><name sortKey="Dominguez, M L" sort="Dominguez, M L" uniqKey="Dominguez M" first="M L" last="Domínguez">M L Domínguez</name>
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<author><name sortKey="Duran, C" sort="Duran, C" uniqKey="Duran C" first="C" last="Durán">C. Durán</name>
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<term>Axilla (diagnostic imaging)</term>
<term>Cardiovascular Diseases (complications)</term>
<term>Cardiovascular Diseases (diagnostic imaging)</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Diagnosis, Differential</term>
<term>Edema (diagnostic imaging)</term>
<term>Edema (etiology)</term>
<term>Female</term>
<term>Groin (diagnostic imaging)</term>
<term>Humans</term>
<term>Infant</term>
<term>Leg Injuries (complications)</term>
<term>Leg Injuries (diagnostic imaging)</term>
<term>Lymphedema (diagnostic imaging)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphoscintigraphy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Neoplasms (complications)</term>
<term>Neoplasms (diagnostic imaging)</term>
<term>Postoperative Complications (diagnostic imaging)</term>
<term>Postoperative Complications (etiology)</term>
<term>Prospective Studies</term>
<term>Radiopharmaceuticals</term>
<term>Sensitivity and Specificity</term>
<term>Technetium Tc 99m Aggregated Albumin</term>
<term>Thrombophlebitis (complications)</term>
<term>Thrombophlebitis (diagnostic imaging)</term>
<term>Young Adult</term>
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<term>Technetium Tc 99m Aggregated Albumin</term>
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<term>Leg Injuries</term>
<term>Neoplasms</term>
<term>Thrombophlebitis</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Axilla</term>
<term>Cardiovascular Diseases</term>
<term>Edema</term>
<term>Groin</term>
<term>Leg Injuries</term>
<term>Lymphedema</term>
<term>Neoplasms</term>
<term>Postoperative Complications</term>
<term>Thrombophlebitis</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Edema</term>
<term>Lymphedema</term>
<term>Postoperative Complications</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Child</term>
<term>Child, Preschool</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
<term>Infant</term>
<term>Lymphoscintigraphy</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Sensitivity and Specificity</term>
<term>Young Adult</term>
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<front><div type="abstract" xml:lang="en">Edema of the limbs is a common reason for medical consultation, for which the lymphoscintigraphy is considered to be a reliable method for its differential diagnosis.</div>
</front>
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<Month>10</Month>
<Day>16</Day>
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<Title>Revista espanola de medicina nuclear e imagen molecular</Title>
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<ArticleTitle>Lymphoscintigraphy for differential diagnosis of peripheral edema: diagnostic yield of different scintigraphic patterns.</ArticleTitle>
<Pagination><MedlinePgn>237-42</MedlinePgn>
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<Abstract><AbstractText Label="UNLABELLED">Edema of the limbs is a common reason for medical consultation, for which the lymphoscintigraphy is considered to be a reliable method for its differential diagnosis.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the usefulness of radionuclide studies in the differential diagnosis of edema, and the diagnostic yield of different scintigraphic patterns.</AbstractText>
<AbstractText Label="MATERIAL AND METHODS" NlmCategory="METHODS">A total of 61 patients, mean age 43 years, referred to our Department in the last three years for suspected lymphoedema, were considered. One patient was discarded due to lack of diagnosis, 56 had lower limb edema and 4 upper limb edema. After intradermal injection of two doses of (99m)Tc-nanocolloid, scintigraphic scans were made at 30 and 120minutes. The final diagnosis was based on imaging tests, clinical course, and response to treatment. We calculated the parameters of the diagnostic yield of four different scintigraphic patterns (presence of dermal backflow, asymmetry-alteration in inguinal/axillary nodes, presence of collateral pathways, and visualization of intermediate lymph nodes), considering them individually and jointly.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The best diagnostic yield was achieved by considering dermal backflow and asymmetry in inguinal/axillary nodes (accuracy 88.9%, specificity 96.4%, PPV 95.5%). Evaluation of intermediate lymph nodes and presence of collateral pathways contributed little to the diagnostic yield, showing poor sensitivity and high false positive rates.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The lymphoscintigraphy had high diagnostic yield, allowing early treatment of lymphœdema. The dermal backflow and asymmetry in inguinal/axillary nodes had the greatest diagnostic accuracy. Evaluation of intermediate lymph nodes and visualization of collateral pathways contributed little to improving the diagnosis.</AbstractText>
<CopyrightInformation>Copyright © 2011 Elsevier España, S.L. y SEMNIM. All rights reserved.</CopyrightInformation>
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