[Iliofemoral cutaneous mucormycosis with endopelvic extension in an immunocompetent child].
Identifieur interne : 001B29 ( PubMed/Corpus ); précédent : 001B28; suivant : 001B30[Iliofemoral cutaneous mucormycosis with endopelvic extension in an immunocompetent child].
Auteurs : S. Elguazzar ; T. Benouachane ; A. Nasri ; A. Malihy ; H. Tligui ; A. BentahilaSource :
- Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [ 1769-664X ] ; 2013.
English descriptors
- KwdEn :
- Amphotericin B (therapeutic use), Antifungal Agents (therapeutic use), Child, Dermatomycoses (diagnosis), Dermatomycoses (drug therapy), Dermatomycoses (microbiology), Erythema (microbiology), Granuloma (pathology), Groin, Humans, Immunocompetence, Itraconazole (therapeutic use), Lymphedema (microbiology), Male, Mucormycosis (diagnosis), Mucormycosis (drug therapy), Pruritus (microbiology).
- MESH :
- chemical , therapeutic use : Amphotericin B, Antifungal Agents, Itraconazole.
- diagnosis : Dermatomycoses, Mucormycosis.
- drug therapy : Dermatomycoses, Mucormycosis.
- microbiology : Dermatomycoses, Erythema, Lymphedema, Pruritus.
- pathology : Granuloma.
- Child, Groin, Humans, Immunocompetence, Male.
Abstract
Mucormycosis is a rare opportunistic fungal infection with clinical polymorphism and is rapidly extensive and destructive. It is caused by fungi of the mucorales group in the environment and generally arises in the context of immunosuppression. Often difficult and late, diagnosis is based on mycological and histological examination. We report the case of a 10-year-old patient admitted for a pruritic erythematous scaly eruption located in the right inguinal area associated with satellite lymphadenopathy and lymphedema of the right lower limb. The histological study of the cutaneous biopsy revealed a granulomatous reaction with filaments. The mycological examination of the collection of the cutaneous lesion showed mucorales filaments and a stump of Absidia corymbifera was isolated. Abdomino-pelvic CT showed muscular extension with vascular and ureteral englobement. The diagnosis of cutaneous mucormycosis was made. Immunological investigations were normal. Treatment included itraconazole for 3months followed by IV amphotericin B for 1month, with favorable clinical and radiological progression. Mucormycosis is an uncommon fungal infection whose cutaneous localization is rare. It occurs exceptionally in immunocompetent patients and is clinically manifested by a vesicular and pustular rash progressing to ulceration. The diagnosis is confirmed by mycological and histological studies. Treatment consists of antifungal therapy associated with surgical excision of necrotic and infected tissue.
DOI: 10.1016/j.arcped.2013.04.003
PubMed: 23706611
Links to Exploration step
pubmed:23706611Le document en format XML
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<author><name sortKey="Elguazzar, S" sort="Elguazzar, S" uniqKey="Elguazzar S" first="S" last="Elguazzar">S. Elguazzar</name>
<affiliation><nlm:affiliation>Service de pédiatrie IV, faculté de médecine et pharmacie, université Mohammed V-Souissi, hôpital d'enfants, avenue Belarbi El Alaoui, BP 6203, Rabat, Maroc. elguazzarsanaa@gmail.com</nlm:affiliation>
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<author><name sortKey="Benouachane, T" sort="Benouachane, T" uniqKey="Benouachane T" first="T" last="Benouachane">T. Benouachane</name>
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<author><name sortKey="Nasri, A" sort="Nasri, A" uniqKey="Nasri A" first="A" last="Nasri">A. Nasri</name>
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<author><name sortKey="Malihy, A" sort="Malihy, A" uniqKey="Malihy A" first="A" last="Malihy">A. Malihy</name>
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<author><name sortKey="Tligui, H" sort="Tligui, H" uniqKey="Tligui H" first="H" last="Tligui">H. Tligui</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Iliofemoral cutaneous mucormycosis with endopelvic extension in an immunocompetent child].</title>
<author><name sortKey="Elguazzar, S" sort="Elguazzar, S" uniqKey="Elguazzar S" first="S" last="Elguazzar">S. Elguazzar</name>
<affiliation><nlm:affiliation>Service de pédiatrie IV, faculté de médecine et pharmacie, université Mohammed V-Souissi, hôpital d'enfants, avenue Belarbi El Alaoui, BP 6203, Rabat, Maroc. elguazzarsanaa@gmail.com</nlm:affiliation>
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<term>Dermatomycoses (drug therapy)</term>
<term>Dermatomycoses (microbiology)</term>
<term>Erythema (microbiology)</term>
<term>Granuloma (pathology)</term>
<term>Groin</term>
<term>Humans</term>
<term>Immunocompetence</term>
<term>Itraconazole (therapeutic use)</term>
<term>Lymphedema (microbiology)</term>
<term>Male</term>
<term>Mucormycosis (diagnosis)</term>
<term>Mucormycosis (drug therapy)</term>
<term>Pruritus (microbiology)</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Amphotericin B</term>
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<term>Mucormycosis</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Granuloma</term>
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<keywords scheme="MESH" xml:lang="en"><term>Child</term>
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<front><div type="abstract" xml:lang="en">Mucormycosis is a rare opportunistic fungal infection with clinical polymorphism and is rapidly extensive and destructive. It is caused by fungi of the mucorales group in the environment and generally arises in the context of immunosuppression. Often difficult and late, diagnosis is based on mycological and histological examination. We report the case of a 10-year-old patient admitted for a pruritic erythematous scaly eruption located in the right inguinal area associated with satellite lymphadenopathy and lymphedema of the right lower limb. The histological study of the cutaneous biopsy revealed a granulomatous reaction with filaments. The mycological examination of the collection of the cutaneous lesion showed mucorales filaments and a stump of Absidia corymbifera was isolated. Abdomino-pelvic CT showed muscular extension with vascular and ureteral englobement. The diagnosis of cutaneous mucormycosis was made. Immunological investigations were normal. Treatment included itraconazole for 3months followed by IV amphotericin B for 1month, with favorable clinical and radiological progression. Mucormycosis is an uncommon fungal infection whose cutaneous localization is rare. It occurs exceptionally in immunocompetent patients and is clinically manifested by a vesicular and pustular rash progressing to ulceration. The diagnosis is confirmed by mycological and histological studies. Treatment consists of antifungal therapy associated with surgical excision of necrotic and infected tissue.</div>
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<Abstract><AbstractText>Mucormycosis is a rare opportunistic fungal infection with clinical polymorphism and is rapidly extensive and destructive. It is caused by fungi of the mucorales group in the environment and generally arises in the context of immunosuppression. Often difficult and late, diagnosis is based on mycological and histological examination. We report the case of a 10-year-old patient admitted for a pruritic erythematous scaly eruption located in the right inguinal area associated with satellite lymphadenopathy and lymphedema of the right lower limb. The histological study of the cutaneous biopsy revealed a granulomatous reaction with filaments. The mycological examination of the collection of the cutaneous lesion showed mucorales filaments and a stump of Absidia corymbifera was isolated. Abdomino-pelvic CT showed muscular extension with vascular and ureteral englobement. The diagnosis of cutaneous mucormycosis was made. Immunological investigations were normal. Treatment included itraconazole for 3months followed by IV amphotericin B for 1month, with favorable clinical and radiological progression. Mucormycosis is an uncommon fungal infection whose cutaneous localization is rare. It occurs exceptionally in immunocompetent patients and is clinically manifested by a vesicular and pustular rash progressing to ulceration. The diagnosis is confirmed by mycological and histological studies. Treatment consists of antifungal therapy associated with surgical excision of necrotic and infected tissue.</AbstractText>
<CopyrightInformation>Copyright © 2013 Elsevier Masson SAS. All rights reserved.</CopyrightInformation>
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<VernacularTitle>Mucormycose cutanée ilio-fémorale avec extension endo-pelvienne chez un enfant immunocompétent.</VernacularTitle>
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