A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal.
Identifieur interne : 001A85 ( PubMed/Corpus ); précédent : 001A84; suivant : 001A86A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal.
Auteurs : Mary M. Barrett ; J Andrew CarlsonSource :
- Journal of lower genital tract disease [ 1526-0976 ] ; 2014.
English descriptors
- KwdEn :
- Adolescent, Adult, Animals, Female, Histocytochemistry, Humans, Hypertrophy (etiology), Hypertrophy (pathology), Immunohistochemistry, Lymphedema (complications), Lymphedema (pathology), Microscopy, Middle Aged, Retrospective Studies, Vulvar Diseases (etiology), Vulvar Diseases (pathology), Young Adult.
- MESH :
- complications : Lymphedema.
- etiology : Hypertrophy, Vulvar Diseases.
- pathology : Hypertrophy, Lymphedema, Vulvar Diseases.
- Adolescent, Adult, Animals, Female, Histocytochemistry, Humans, Immunohistochemistry, Microscopy, Middle Aged, Retrospective Studies, Young Adult.
Abstract
To describe the clinical and pathologic features of women undergoing labioplasty for labia minora hypertrophy (LH) and to determine whether localized lymphedema plays a role in its pathogenesis.
DOI: 10.1097/LGT.0b013e31828d3989
PubMed: 23760147
Links to Exploration step
pubmed:23760147Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal.</title><author><name sortKey="Barrett, Mary M" sort="Barrett, Mary M" uniqKey="Barrett M" first="Mary M" last="Barrett">Mary M. Barrett</name><affiliation><nlm:affiliation>Department of Pathology, Albany Medical College, Albany, NY.</nlm:affiliation></affiliation></author><author><name sortKey="Carlson, J Andrew" sort="Carlson, J Andrew" uniqKey="Carlson J" first="J Andrew" last="Carlson">J Andrew Carlson</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:23760147</idno><idno type="pmid">23760147</idno><idno type="doi">10.1097/LGT.0b013e31828d3989</idno><idno type="wicri:Area/PubMed/Corpus">001A85</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001A85</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal.</title><author><name sortKey="Barrett, Mary M" sort="Barrett, Mary M" uniqKey="Barrett M" first="Mary M" last="Barrett">Mary M. Barrett</name><affiliation><nlm:affiliation>Department of Pathology, Albany Medical College, Albany, NY.</nlm:affiliation></affiliation></author><author><name sortKey="Carlson, J Andrew" sort="Carlson, J Andrew" uniqKey="Carlson J" first="J Andrew" last="Carlson">J Andrew Carlson</name></author></analytic><series><title level="j">Journal of lower genital tract disease</title><idno type="eISSN">1526-0976</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Female</term><term>Histocytochemistry</term><term>Humans</term><term>Hypertrophy (etiology)</term><term>Hypertrophy (pathology)</term><term>Immunohistochemistry</term><term>Lymphedema (complications)</term><term>Lymphedema (pathology)</term><term>Microscopy</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Vulvar Diseases (etiology)</term><term>Vulvar Diseases (pathology)</term><term>Young Adult</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypertrophy</term><term>Vulvar Diseases</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Hypertrophy</term><term>Lymphedema</term><term>Vulvar Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Animals</term><term>Female</term><term>Histocytochemistry</term><term>Humans</term><term>Immunohistochemistry</term><term>Microscopy</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Young Adult</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To describe the clinical and pathologic features of women undergoing labioplasty for labia minora hypertrophy (LH) and to determine whether localized lymphedema plays a role in its pathogenesis.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23760147</PMID><DateCreated><Year>2013</Year><Month>12</Month><Day>30</Day></DateCreated><DateCompleted><Year>2014</Year><Month>08</Month><Day>21</Day></DateCompleted><DateRevised><Year>2015</Year><Month>05</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1526-0976</ISSN><JournalIssue CitedMedium="Internet"><Volume>18</Volume><Issue>1</Issue><PubDate><Year>2014</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Journal of lower genital tract disease</Title><ISOAbbreviation>J Low Genit Tract Dis</ISOAbbreviation></Journal><ArticleTitle>A clinicopathologic study of labia minora hypertrophy: signs of localized lymphedema were universal.</ArticleTitle><Pagination><MedlinePgn>13-20</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/LGT.0b013e31828d3989</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To describe the clinical and pathologic features of women undergoing labioplasty for labia minora hypertrophy (LH) and to determine whether localized lymphedema plays a role in its pathogenesis.</AbstractText><AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">A retrospective case series of consecutive cases of labioplasties performed for LH was retrieved from a 10-year period. Clinical, histopathologic, and immunohistochemical features were evaluated.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Thirty-four labioplasty specimens from 31 women were identified. The women had a median/mean age of 36/35 years (range = 14-62 y) and had noted the presence of LH for a median/mean period of 36/86 months (range = 5-264 mo). A minority of patients had antecedent vaginal delivery (29%) and vulvar trauma (12%) and were either overweight (20%) or obese (27%). About half complained of vulvar appearance and approximately a third each had symptoms of pain, dyspareunia, or irritation. After a median/mean follow-up time of 40/44 months, 3 patients had recurrent LH (9%). The volume of excised tissue was greater for the patients with recurrent LH, than those without (mean of 9.8 vs 5.6 mL, respectively); however, no clinicopathologic finding predicted recurrence of LH. Histopathologically, all LH specimens showed diagnostic signs of chronic lymphedema, and compared with vulvar controls, LH had a significantly greater number of lymphangiectases (mean 15/mm vs 3/mm, p = .001) and showed greater mean maximal lymphatic dilation (0.12 vs 0.04 mm, p = .004), respectively. In addition, lichenification (94%), indicating chronic irritation, and sebaceous hyperplasia (60%), perisebaceous inflammation, and Demodex folliculorum infestation (3%), a constellation of findings commonly seen in phymatous rosacea, were evident.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Rather than an anatomic variant, LH seems to be a manifestation of chronic lymphedema, either acquired or primary with delayed onset. Because persistent lymphedema can lead to functional debilitation, recurrent skin infections, elephantiasis, and, rarely, malignancy, early excision and treatment of factors that promote lymphedema would be effective management of this rare condition.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Barrett</LastName><ForeName>Mary M</ForeName><Initials>MM</Initials><AffiliationInfo><Affiliation>Department of Pathology, Albany Medical College, Albany, NY.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Carlson</LastName><ForeName>J Andrew</ForeName><Initials>JA</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Low Genit Tract Dis</MedlineTA><NlmUniqueID>9704963</NlmUniqueID><ISSNLinking>1089-2591</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>J Low Genit Tract Dis. 2015 Apr;19(2):e50</RefSource><PMID Version="1">25811280</PMID></CommentsCorrections><CommentsCorrections RefType="CommentIn"><RefSource>J Low Genit Tract Dis. 2015 Apr;19(2):e49-50</RefSource><PMID Version="1">25811279</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006651" MajorTopicYN="N">Histocytochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006984" MajorTopicYN="N">Hypertrophy</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008853" MajorTopicYN="N">Microscopy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014845" MajorTopicYN="N">Vulvar Diseases</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>6</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>6</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>8</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23760147</ArticleId><ArticleId IdType="doi">10.1097/LGT.0b013e31828d3989</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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