LymphedemaV1, PubMed, Corpus, bibRecord, 000D65

INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.

Identifieur interne : 000D65 ( PubMed/Corpus ); précédent : 000D64; suivant : 000D66

INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.

Auteurs : Lubna Mushtaque Vohra ; Rubina Gulzar ; Omema Saleem

Source :

Journal of Ayub Medical College, Abbottabad : JAMC [ 1025-9589 ]

RBID : pubmed:26182734

English descriptors

KwdEn :
- Adult, Aged, Axilla, Breast Neoplasms (diagnosis), Breast Neoplasms (secondary), Breast Neoplasms (surgery), Female, Frozen Sections, Humans, Intraoperative Period, Lymph Node Excision, Lymph Nodes (pathology), Lymph Nodes (surgery), Lymphatic Metastasis, Mastectomy, Middle Aged, Neoplasm Staging (methods), Prospective Studies, Reproducibility of Results, Sentinel Lymph Node Biopsy (methods).
MESH :
- diagnosis : Breast Neoplasms.
- methods : Neoplasm Staging, Sentinel Lymph Node Biopsy.
- pathology : Lymph Nodes.
- secondary : Breast Neoplasms.
- surgery : Breast Neoplasms, Lymph Nodes.
- Adult, Aged, Axilla, Female, Frozen Sections, Humans, Intraoperative Period, Lymph Node Excision, Lymphatic Metastasis, Mastectomy, Middle Aged, Prospective Studies, Reproducibility of Results.

Abstract

Sentinel node (SN) biopsy is the standard of care for the assessment of axilla in early breast cancer patients with clinically node negative disease. Confirmed absence of tumour deposit in node on intra operative frozen section (FS) examination saves the patient from complete axillary dissection. However controversies arise when inconsistencies occur in results of frozen and permanent section. Reported sensitivity of frozen examination of sentinel node in literature ranges from 70-95%.The purpose of this study was to determine the sensitivity of frozen examination of sentinel node in breast cancer. The frozen section examination of sentinel node is not a reliable technique for accurate pathological assessment of node.

PubMed: 26182734

Links to Exploration step

pubmed:26182734

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.</title>
<author><name sortKey="Vohra, Lubna Mushtaque" sort="Vohra, Lubna Mushtaque" uniqKey="Vohra L" first="Lubna Mushtaque" last="Vohra">Lubna Mushtaque Vohra</name>
</author>
<author><name sortKey="Gulzar, Rubina" sort="Gulzar, Rubina" uniqKey="Gulzar R" first="Rubina" last="Gulzar">Rubina Gulzar</name>
</author>
<author><name sortKey="Saleem, Omema" sort="Saleem, Omema" uniqKey="Saleem O" first="Omema" last="Saleem">Omema Saleem</name>
</author>
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<date when="????"><PubDate><MedlineDate>2015 Jan-Mar</MedlineDate>
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<idno type="RBID">pubmed:26182734</idno>
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<idno type="wicri:Area/PubMed/Corpus">000D65</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.</title>
<author><name sortKey="Vohra, Lubna Mushtaque" sort="Vohra, Lubna Mushtaque" uniqKey="Vohra L" first="Lubna Mushtaque" last="Vohra">Lubna Mushtaque Vohra</name>
</author>
<author><name sortKey="Gulzar, Rubina" sort="Gulzar, Rubina" uniqKey="Gulzar R" first="Rubina" last="Gulzar">Rubina Gulzar</name>
</author>
<author><name sortKey="Saleem, Omema" sort="Saleem, Omema" uniqKey="Saleem O" first="Omema" last="Saleem">Omema Saleem</name>
</author>
</analytic>
<series><title level="j">Journal of Ayub Medical College, Abbottabad : JAMC</title>
<idno type="ISSN">1025-9589</idno>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Axilla</term>
<term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (secondary)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Female</term>
<term>Frozen Sections</term>
<term>Humans</term>
<term>Intraoperative Period</term>
<term>Lymph Node Excision</term>
<term>Lymph Nodes (pathology)</term>
<term>Lymph Nodes (surgery)</term>
<term>Lymphatic Metastasis</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Neoplasm Staging (methods)</term>
<term>Prospective Studies</term>
<term>Reproducibility of Results</term>
<term>Sentinel Lymph Node Biopsy (methods)</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neoplasm Staging</term>
<term>Sentinel Lymph Node Biopsy</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymph Nodes</term>
</keywords>
<keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Breast Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Breast Neoplasms</term>
<term>Lymph Nodes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Axilla</term>
<term>Female</term>
<term>Frozen Sections</term>
<term>Humans</term>
<term>Intraoperative Period</term>
<term>Lymph Node Excision</term>
<term>Lymphatic Metastasis</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Reproducibility of Results</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Sentinel node (SN) biopsy is the standard of care for the assessment of axilla in early breast cancer patients with clinically node negative disease. Confirmed absence of tumour deposit in node on intra operative frozen section (FS) examination saves the patient from complete axillary dissection. However controversies arise when inconsistencies occur in results of frozen and permanent section. Reported sensitivity of frozen examination of sentinel node in literature ranges from 70-95%.The purpose of this study was to determine the sensitivity of frozen examination of sentinel node in breast cancer. The frozen section examination of sentinel node is not a reliable technique for accurate pathological assessment of node.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26182734</PMID>
<DateCreated><Year>2015</Year>
<Month>07</Month>
<Day>17</Day>
</DateCreated>
<DateCompleted><Year>2015</Year>
<Month>08</Month>
<Day>27</Day>
</DateCompleted>
<DateRevised><Year>2015</Year>
<Month>07</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">1025-9589</ISSN>
<JournalIssue CitedMedium="Print"><Volume>27</Volume>
<Issue>1</Issue>
<PubDate><MedlineDate>2015 Jan-Mar</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Journal of Ayub Medical College, Abbottabad : JAMC</Title>
<ISOAbbreviation>J Ayub Med Coll Abbottabad</ISOAbbreviation>
</Journal>
<ArticleTitle>INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.</ArticleTitle>
<Pagination><MedlinePgn>40-4</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Sentinel node (SN) biopsy is the standard of care for the assessment of axilla in early breast cancer patients with clinically node negative disease. Confirmed absence of tumour deposit in node on intra operative frozen section (FS) examination saves the patient from complete axillary dissection. However controversies arise when inconsistencies occur in results of frozen and permanent section. Reported sensitivity of frozen examination of sentinel node in literature ranges from 70-95%.The purpose of this study was to determine the sensitivity of frozen examination of sentinel node in breast cancer. The frozen section examination of sentinel node is not a reliable technique for accurate pathological assessment of node.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Data was collected prospectively on patients with sentinel node procedure from May to December 2013. All SNs removed at surgery were submitted for frozen section and the results were compared with permanent sections.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 50 patients 16 were true positive while 32 were true negative. Two patients reported negative on FS were confirmed to be positive on permanent section. The accuracy of frozen section was 96%, with sensitivity of 89%. In false negative cases the size of nodal metastasis was significantly smaller than that of true positive, i.e., 1-2 mm. The false negative cases were further classified for assessment into technical and interpretative error.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The intra operative frozen section examination is a reliable technique for the assessment of Sentinel node with a high accuracy rate to detect metastasis size of >2 mm. It spares the patient from complete axillary dissection and its subsequent morbidity of lymphedema and shoulder pain.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vohra</LastName>
<ForeName>Lubna Mushtaque</ForeName>
<Initials>LM</Initials>
</Author>
<Author ValidYN="Y"><LastName>Gulzar</LastName>
<ForeName>Rubina</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Saleem</LastName>
<ForeName>Omema</ForeName>
<Initials>O</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Pakistan</Country>
<MedlineTA>J Ayub Med Coll Abbottabad</MedlineTA>
<NlmUniqueID>8910750</NlmUniqueID>
<ISSNLinking>1025-9589</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001365" MajorTopicYN="N">Axilla</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
<QualifierName UI="Q000556" MajorTopicYN="Y">secondary</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005629" MajorTopicYN="N">Frozen Sections</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007432" MajorTopicYN="N">Intraoperative Period</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008198" MajorTopicYN="N">Lymph Nodes</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008207" MajorTopicYN="N">Lymphatic Metastasis</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008408" MajorTopicYN="Y">Mastectomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009367" MajorTopicYN="N">Neoplasm Staging</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D021701" MajorTopicYN="N">Sentinel Lymph Node Biopsy</DescriptorName>
<QualifierName UI="Q000379" MajorTopicYN="Y">methods</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2015</Year>
<Month>7</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2015</Year>
<Month>7</Month>
<Day>18</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2015</Year>
<Month>8</Month>
<Day>28</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">26182734</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

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INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.

INTRA OPERATIVE FROZEN EXAMINATION OF SENTINEL LYMPH NODE IN BREAST CANCER.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki