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Sympathetic Block as a New Treatment for Lymphedema.

Identifieur interne : 000D44 ( PubMed/Corpus ); précédent : 000D43; suivant : 000D45

Sympathetic Block as a New Treatment for Lymphedema.

Auteurs : Eunjoo Choi ; Francis Sahngun Nahm ; Pyung-Bok Lee

Source :

RBID : pubmed:26218940

English descriptors

Abstract

Breast cancer-related lymphedema (BCRL) not only has physical implications, but also affects the quality of life in breast cancer survivors. Despite numerous studies of various therapies, the optimal treatment for BCRL is unknown.

PubMed: 26218940

Links to Exploration step

pubmed:26218940

Le document en format XML

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<title xml:lang="en">Sympathetic Block as a New Treatment for Lymphedema.</title>
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<name sortKey="Choi, Eunjoo" sort="Choi, Eunjoo" uniqKey="Choi E" first="Eunjoo" last="Choi">Eunjoo Choi</name>
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<nlm:affiliation>Department of Anesthesiology and Pain Medicine., Seoul National University Bundang Hospital, Seongnam-si, Bundang-gu Korea.</nlm:affiliation>
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<author>
<name sortKey="Nahm, Francis Sahngun" sort="Nahm, Francis Sahngun" uniqKey="Nahm F" first="Francis Sahngun" last="Nahm">Francis Sahngun Nahm</name>
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<name sortKey="Lee, Pyung Bok" sort="Lee, Pyung Bok" uniqKey="Lee P" first="Pyung-Bok" last="Lee">Pyung-Bok Lee</name>
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<title xml:lang="en">Sympathetic Block as a New Treatment for Lymphedema.</title>
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<name sortKey="Choi, Eunjoo" sort="Choi, Eunjoo" uniqKey="Choi E" first="Eunjoo" last="Choi">Eunjoo Choi</name>
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<nlm:affiliation>Department of Anesthesiology and Pain Medicine., Seoul National University Bundang Hospital, Seongnam-si, Bundang-gu Korea.</nlm:affiliation>
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<name sortKey="Nahm, Francis Sahngun" sort="Nahm, Francis Sahngun" uniqKey="Nahm F" first="Francis Sahngun" last="Nahm">Francis Sahngun Nahm</name>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Arm (pathology)</term>
<term>Autonomic Nerve Block (methods)</term>
<term>Breast Neoplasms (diagnosis)</term>
<term>Breast Neoplasms (epidemiology)</term>
<term>Breast Neoplasms (therapy)</term>
<term>Female</term>
<term>Humans</term>
<term>Lymphedema (diagnosis)</term>
<term>Lymphedema (epidemiology)</term>
<term>Lymphedema (therapy)</term>
<term>Middle Aged</term>
<term>Quality of Life (psychology)</term>
<term>Retrospective Studies</term>
<term>Treatment Outcome</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en">
<term>Breast Neoplasms</term>
<term>Lymphedema</term>
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<term>Breast Neoplasms</term>
<term>Lymphedema</term>
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<term>Autonomic Nerve Block</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Arm</term>
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<keywords scheme="MESH" qualifier="psychology" xml:lang="en">
<term>Quality of Life</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en">
<term>Breast Neoplasms</term>
<term>Lymphedema</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
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<div type="abstract" xml:lang="en">Breast cancer-related lymphedema (BCRL) not only has physical implications, but also affects the quality of life in breast cancer survivors. Despite numerous studies of various therapies, the optimal treatment for BCRL is unknown.</div>
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<Year>2015</Year>
<Month>07</Month>
<Day>29</Day>
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<DateCompleted>
<Year>2016</Year>
<Month>02</Month>
<Day>17</Day>
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<Year>2015</Year>
<Month>07</Month>
<Day>29</Day>
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<Volume>18</Volume>
<Issue>4</Issue>
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<MedlineDate>2015 Jul-Aug</MedlineDate>
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<Title>Pain physician</Title>
<ISOAbbreviation>Pain Physician</ISOAbbreviation>
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<ArticleTitle>Sympathetic Block as a New Treatment for Lymphedema.</ArticleTitle>
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<MedlinePgn>365-72</MedlinePgn>
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<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Breast cancer-related lymphedema (BCRL) not only has physical implications, but also affects the quality of life in breast cancer survivors. Despite numerous studies of various therapies, the optimal treatment for BCRL is unknown.</AbstractText>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">In this study, we investigated the efficacy of sympathetic blockade (thoracic sympathetic ganglion block, [TSGB]) in treating BCRL.</AbstractText>
<AbstractText Label="STUDY DESIGN" NlmCategory="METHODS">Retrospective study.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Tertiary referral center/teaching hospital.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">TSGB was performed in 35 patients under fluoroscopic guidance. First, arm circumference and Lymphedema and Breast Cancer Questionnaire [LBCQ] score were assessed before TSGB and 2 weeks and 2 months after the procedure. Efficacy was defined as a ≥ 50% reduction in the LBCQ score and a ≥ 50% decrease in the circumference difference between the unaffected and affected arms 2 months after TSGB. Second, TSGB efficacy according to the lymphedema stage and the period between BCRL onset and TSGB (< 6 months vs. > 6 months) was evaluated.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The arm circumference and LBCQ score significantly decreased at 2 months (P < 0.001), and 65.7% of patients showed good efficacy. Patients with high stage lymphedema showed improved efficacy after TSGB compared to those with low stage disease (P = 0.045). The TSGB efficacy did not differ according to the period between BCRL onset and TSGB.</AbstractText>
<AbstractText Label="LIMITATIONS" NlmCategory="CONCLUSIONS">This study was not a randomized prospective controlled study and did not compare the therapeutic outcomes to those in a conservative treatment group.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">TSGB in BCRL patients appears to be effective in decreasing the affected arm circumference. TSGB may be an alternative option in BCRL patients who do not respond to conservative therapy.</AbstractText>
</Abstract>
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