Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.
Identifieur interne : 000B69 ( PubMed/Corpus ); précédent : 000B68; suivant : 000B70Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.
Auteurs : Katherine E. Mues ; Patrick J. Lammie ; Mitchel Klein ; David G. Kleinbaum ; David Addiss ; Leanne M. FoxSource :
- PloS one [ 1932-6203 ] ; 2015.
English descriptors
- KwdEn :
- Adult, Animals, Antibodies, Bacterial (blood), Antibodies, Bacterial (immunology), Antibodies, Fungal (blood), Antibodies, Fungal (immunology), Antibodies, Protozoan (blood), Antibodies, Protozoan (immunology), Cohort Studies, Elephantiasis, Filarial (etiology), Female, Haiti, Humans, Lymphangitis (blood), Lymphangitis (etiology), Lymphangitis (immunology), Lymphedema (blood), Lymphedema (immunology), Male, Streptococcus pyogenes (immunology), Wuchereria bancrofti (immunology).
- MESH :
- chemical , blood : Antibodies, Bacterial, Antibodies, Fungal, Antibodies, Protozoan.
- chemical , immunology : Antibodies, Bacterial, Antibodies, Fungal, Antibodies, Protozoan.
- geographic : Haiti.
- blood : Lymphangitis, Lymphedema.
- etiology : Elephantiasis, Filarial, Lymphangitis.
- immunology : Lymphangitis, Lymphedema, Streptococcus pyogenes, Wuchereria bancrofti.
- Adult, Animals, Cohort Studies, Female, Humans, Male.
Abstract
Episodes of acute adenolymphangitis (ADL) are often the first clinical sign of lymphatic filariasis (LF). They are often accompanied by swelling of the affected limb, inflammation, fever, and general malaise and lead to the progression of lymphedema. Although ADL episodes have been studied for a century or more, questions still remain as to their etiology. We quantified antibody levels to pathogens that potentially contribute to ADL episodes during and after an episode among lymphedema patients in Léogâne, Haiti. We estimated the proportion of ADL episodes hypothesized to be attributed to specific pathogens.
DOI: 10.1371/journal.pone.0141047
PubMed: 26492462
Links to Exploration step
pubmed:26492462Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.</title><author><name sortKey="Mues, Katherine E" sort="Mues, Katherine E" uniqKey="Mues K" first="Katherine E" last="Mues">Katherine E. Mues</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J" last="Lammie">Patrick J. Lammie</name><affiliation><nlm:affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Klein, Mitchel" sort="Klein, Mitchel" uniqKey="Klein M" first="Mitchel" last="Klein">Mitchel Klein</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Kleinbaum, David G" sort="Kleinbaum, David G" uniqKey="Kleinbaum D" first="David G" last="Kleinbaum">David G. Kleinbaum</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Addiss, David" sort="Addiss, David" uniqKey="Addiss D" first="David" last="Addiss">David Addiss</name><affiliation><nlm:affiliation>Task Force for Global Health, Decatur, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Leanne M" sort="Fox, Leanne M" uniqKey="Fox L" first="Leanne M" last="Fox">Leanne M. Fox</name><affiliation><nlm:affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26492462</idno><idno type="pmid">26492462</idno><idno type="doi">10.1371/journal.pone.0141047</idno><idno type="wicri:Area/PubMed/Corpus">000B69</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B69</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.</title><author><name sortKey="Mues, Katherine E" sort="Mues, Katherine E" uniqKey="Mues K" first="Katherine E" last="Mues">Katherine E. Mues</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Lammie, Patrick J" sort="Lammie, Patrick J" uniqKey="Lammie P" first="Patrick J" last="Lammie">Patrick J. Lammie</name><affiliation><nlm:affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Klein, Mitchel" sort="Klein, Mitchel" uniqKey="Klein M" first="Mitchel" last="Klein">Mitchel Klein</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Kleinbaum, David G" sort="Kleinbaum, David G" uniqKey="Kleinbaum D" first="David G" last="Kleinbaum">David G. Kleinbaum</name><affiliation><nlm:affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Addiss, David" sort="Addiss, David" uniqKey="Addiss D" first="David" last="Addiss">David Addiss</name><affiliation><nlm:affiliation>Task Force for Global Health, Decatur, Georgia, United States of America.</nlm:affiliation></affiliation></author><author><name sortKey="Fox, Leanne M" sort="Fox, Leanne M" uniqKey="Fox L" first="Leanne M" last="Fox">Leanne M. Fox</name><affiliation><nlm:affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</nlm:affiliation></affiliation></author></analytic><series><title level="j">PloS one</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Animals</term><term>Antibodies, Bacterial (blood)</term><term>Antibodies, Bacterial (immunology)</term><term>Antibodies, Fungal (blood)</term><term>Antibodies, Fungal (immunology)</term><term>Antibodies, Protozoan (blood)</term><term>Antibodies, Protozoan (immunology)</term><term>Cohort Studies</term><term>Elephantiasis, Filarial (etiology)</term><term>Female</term><term>Haiti</term><term>Humans</term><term>Lymphangitis (blood)</term><term>Lymphangitis (etiology)</term><term>Lymphangitis (immunology)</term><term>Lymphedema (blood)</term><term>Lymphedema (immunology)</term><term>Male</term><term>Streptococcus pyogenes (immunology)</term><term>Wuchereria bancrofti (immunology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Antibodies, Bacterial</term><term>Antibodies, Fungal</term><term>Antibodies, Protozoan</term></keywords><keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antibodies, Bacterial</term><term>Antibodies, Fungal</term><term>Antibodies, Protozoan</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Haiti</term></keywords><keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Lymphangitis</term><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Lymphangitis</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Lymphangitis</term><term>Lymphedema</term><term>Streptococcus pyogenes</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Animals</term><term>Cohort Studies</term><term>Female</term><term>Humans</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Episodes of acute adenolymphangitis (ADL) are often the first clinical sign of lymphatic filariasis (LF). They are often accompanied by swelling of the affected limb, inflammation, fever, and general malaise and lead to the progression of lymphedema. Although ADL episodes have been studied for a century or more, questions still remain as to their etiology. We quantified antibody levels to pathogens that potentially contribute to ADL episodes during and after an episode among lymphedema patients in Léogâne, Haiti. We estimated the proportion of ADL episodes hypothesized to be attributed to specific pathogens.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26492462</PMID><DateCreated><Year>2015</Year><Month>10</Month><Day>23</Day></DateCreated><DateCompleted><Year>2016</Year><Month>06</Month><Day>30</Day></DateCompleted><DateRevised><Year>2015</Year><Month>10</Month><Day>30</Day></DateRevised><Article PubModel="Electronic-eCollection"><Journal><ISSN IssnType="Electronic">1932-6203</ISSN><JournalIssue CitedMedium="Internet"><Volume>10</Volume><Issue>10</Issue><PubDate><Year>2015</Year></PubDate></JournalIssue><Title>PloS one</Title><ISOAbbreviation>PLoS ONE</ISOAbbreviation></Journal><ArticleTitle>Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.</ArticleTitle><Pagination><MedlinePgn>e0141047</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1371/journal.pone.0141047</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Episodes of acute adenolymphangitis (ADL) are often the first clinical sign of lymphatic filariasis (LF). They are often accompanied by swelling of the affected limb, inflammation, fever, and general malaise and lead to the progression of lymphedema. Although ADL episodes have been studied for a century or more, questions still remain as to their etiology. We quantified antibody levels to pathogens that potentially contribute to ADL episodes during and after an episode among lymphedema patients in Léogâne, Haiti. We estimated the proportion of ADL episodes hypothesized to be attributed to specific pathogens.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We measured antibody levels to specific pathogens during and following an ADL episode among 41 lymphedema patients enrolled in a cohort study in Léogâne, Haiti. We calculated the absolute and relative changes in antibody levels between the ADL and convalescent time points. We calculated the proportion of episodes that demonstrated a two-fold increase in antibody level for several bacterial, fungal, and filarial pathogens.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Our results showed the greatest proportion of two-fold changes in antibody levels for the carbohydrate antigen Streptococcus group A, followed by IgG2 responses to a soluble filarial antigen (BpG2), Streptococcal Pyrogenic Exotoxin B, and an antigen for the fungal pathogen Candida. When comparing the median antibody level during the ADL episode to the median antibody level at the convalescent time point, only the antigens for Pseudomonas species (P-value = 0.0351) and Streptolysin O (P-value = 0.0074) showed a significant result.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Although our results are limited by the lack of a control group and few antibody responses, they provide some evidence for infection with Streptococcus A as a potential contributing factor to ADL episodes. Our results add to the current evidence and illustrate the importance of determining the causal role of bacterial and fungal pathogens and immunological antifilarial response in ADL episodes.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mues</LastName><ForeName>Katherine E</ForeName><Initials>KE</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lammie</LastName><ForeName>Patrick J</ForeName><Initials>PJ</Initials><AffiliationInfo><Affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Klein</LastName><ForeName>Mitchel</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kleinbaum</LastName><ForeName>David G</ForeName><Initials>DG</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, Rollins School of Public Health and Laney Graduate School, Emory University, Atlanta, Georgia, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Addiss</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Task Force for Global Health, Decatur, Georgia, United States of America.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Fox</LastName><ForeName>LeAnne M</ForeName><Initials>LM</Initials><AffiliationInfo><Affiliation>Parasitic Diseases Branch, Division of Parasitic Diseases and Malaria, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>10</Month><Day>22</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>PLoS One</MedlineTA><NlmUniqueID>101285081</NlmUniqueID><ISSNLinking>1932-6203</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000907">Antibodies, Bacterial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000908">Antibodies, Fungal</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000913">Antibodies, Protozoan</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Am J Epidemiol. 1978 Dec;108(6):447-53</RefSource><PMID Version="1">736024</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 1996 Sep;64(9):3461-6</RefSource><PMID Version="1">8751885</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2003 Dec;8(12):1102-9</RefSource><PMID Version="1">14641845</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 2003 Jan;8(1):56-9</RefSource><PMID Version="1">12535251</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>N Engl J Med. 2002 Dec 5;347(23):1841-8</RefSource><PMID Version="1">12466508</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2002 Feb;66(2):163-9</RefSource><PMID Version="1">12135288</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Indian J Public Health. 1999 Apr-Jun;43(2):58-63</RefSource><PMID Version="1">11243067</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasite. 2000 Jun;7(2):91-4</RefSource><PMID Version="1">10887654</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1999 Jul-Aug;93(4):413-7</RefSource><PMID Version="1">10674092</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2014 Nov;8(11):e3319</RefSource><PMID Version="1">25412180</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Southeast Asian J Trop Med Public Health. 1995 Jun;26(2):301-5</RefSource><PMID Version="1">8629065</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1995 Jan-Feb;89(1):72-4</RefSource><PMID Version="1">7747314</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>East Afr Med J. 1995 Aug;72(8):492-4</RefSource><PMID Version="1">7588141</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 1995 Sep;102:114-8</RefSource><PMID Version="1">8543349</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 1994 Apr;88(2):153-61</RefSource><PMID Version="1">8067811</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):230-3</RefSource><PMID Version="1">8337737</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 1993 May 1;150(9):3941-50</RefSource><PMID Version="1">8473742</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasitology. 1992;104 Suppl:S71-9</RefSource><PMID Version="1">1589302</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Pediatr Infect Dis J. 1991 Oct;10(10 Suppl):S15-9</RefSource><PMID Version="1">1945591</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trop Med Parasitol. 1990 Dec;41(4):403-6</RefSource><PMID Version="1">2075384</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 1990 Dec 15;145(12):4298-305</RefSource><PMID Version="1">2258618</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Bull World Health Organ. 1985;63(5):869-80</RefSource><PMID Version="1">3912078</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 1982 Jun;75:813-5</RefSource><PMID Version="1">7129551</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Infect Dis. 2012 Sep;55(5):621-30</RefSource><PMID Version="1">22610930</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2011 Jul;5(7):e1241</RefSource><PMID Version="1">21765964</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2010;4(4):e668</RefSource><PMID Version="1">20422031</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Dermatol. 2006 May;154(5):933-41</RefSource><PMID Version="1">16634898</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Southeast Asian J Trop Med Public Health. 1997 Dec;28(4):826-30</RefSource><PMID Version="1">9656409</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Parasitol. 1998 Jun;84(3):557-61</RefSource><PMID Version="1">9645857</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 1998 Apr;20(4):155-62</RefSource><PMID Version="1">9618725</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 1997 Jul;57(1):7-15</RefSource><PMID Version="1">9242310</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Epidemiol. 1976 Dec;104(6):587-92</RefSource><PMID Version="1">998606</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000908" MajorTopicYN="N">Antibodies, Fungal</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000913" MajorTopicYN="N">Antibodies, Protozoan</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006205" MajorTopicYN="N" Type="Geographic">Haiti</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008205" MajorTopicYN="N">Lymphangitis</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013297" MajorTopicYN="N">Streptococcus pyogenes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4619626</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>07</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>10</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>10</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>10</Month><Day>23</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>7</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26492462</ArticleId><ArticleId IdType="doi">10.1371/journal.pone.0141047</ArticleId><ArticleId IdType="pii">PONE-D-15-32812</ArticleId><ArticleId IdType="pmc">PMC4619626</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B69 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000B69 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:26492462
|texte= Changes in Antibody Levels during and following an Episode of Acute Adenolymphangitis (ADL) among Lymphedema Patients in Léogâne, Haiti.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:26492462" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |