Mapping is a prerequisite for elimination of filariasis and effective targeting of filarial 'hot spots'.
Identifieur interne : 000714 ( PubMed/Corpus ); précédent : 000713; suivant : 000715Mapping is a prerequisite for elimination of filariasis and effective targeting of filarial 'hot spots'.
Auteurs : Gyan Chand ; Laxman Singh Kaushal ; Narendra Kumar Choudhari ; Neeru SinghSource :
- Pathogens and global health [ 2047-7732 ]
English descriptors
- KwdEn :
- Adolescent, Adult, Animals, Child, Culex (parasitology), Disease Eradication, Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (prevention & control), Female, Geography, Humans, India (epidemiology), Insect Vectors (parasitology), Male, Microfilariae, Middle Aged, Prevalence, Wuchereria bancrofti (isolation & purification), Young Adult.
- MESH :
- epidemiology : Elephantiasis, Filarial, India.
- isolation & purification : Wuchereria bancrofti.
- parasitology : Culex, Elephantiasis, Filarial, Insect Vectors.
- prevention & control : Elephantiasis, Filarial.
- Adolescent, Adult, Animals, Child, Disease Eradication, Female, Geography, Humans, Male, Microfilariae, Middle Aged, Prevalence, Young Adult.
Abstract
This study was undertaken to determine the prevalence of filarial infection in the districts of Madhya Pradesh, which were classified as non-endemic by the national program for control of filariasis. These districts showed evidence of clinical symptoms related to filariasis. To confirm the presence of filariasis, night blood surveys and entomological surveys were carried out to detect microfilaria in humans and filarial infection in vectors.
DOI: 10.1080/20477724.2016.1205302
PubMed: 27413817
Links to Exploration step
pubmed:27413817Le document en format XML
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<author><name sortKey="Chand, Gyan" sort="Chand, Gyan" uniqKey="Chand G" first="Gyan" last="Chand">Gyan Chand</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<author><name sortKey="Kaushal, Laxman Singh" sort="Kaushal, Laxman Singh" uniqKey="Kaushal L" first="Laxman Singh" last="Kaushal">Laxman Singh Kaushal</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Choudhari, Narendra Kumar" sort="Choudhari, Narendra Kumar" uniqKey="Choudhari N" first="Narendra Kumar" last="Choudhari">Narendra Kumar Choudhari</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<author><name sortKey="Singh, Neeru" sort="Singh, Neeru" uniqKey="Singh N" first="Neeru" last="Singh">Neeru Singh</name>
<affiliation><nlm:affiliation>b Department of Epidemiology and Vector Control , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Mapping is a prerequisite for elimination of filariasis and effective targeting of filarial 'hot spots'.</title>
<author><name sortKey="Chand, Gyan" sort="Chand, Gyan" uniqKey="Chand G" first="Gyan" last="Chand">Gyan Chand</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<author><name sortKey="Kaushal, Laxman Singh" sort="Kaushal, Laxman Singh" uniqKey="Kaushal L" first="Laxman Singh" last="Kaushal">Laxman Singh Kaushal</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
</affiliation>
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<author><name sortKey="Choudhari, Narendra Kumar" sort="Choudhari, Narendra Kumar" uniqKey="Choudhari N" first="Narendra Kumar" last="Choudhari">Narendra Kumar Choudhari</name>
<affiliation><nlm:affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<author><name sortKey="Singh, Neeru" sort="Singh, Neeru" uniqKey="Singh N" first="Neeru" last="Singh">Neeru Singh</name>
<affiliation><nlm:affiliation>b Department of Epidemiology and Vector Control , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</nlm:affiliation>
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<series><title level="j">Pathogens and global health</title>
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<term>Child</term>
<term>Culex (parasitology)</term>
<term>Disease Eradication</term>
<term>Elephantiasis, Filarial (epidemiology)</term>
<term>Elephantiasis, Filarial (parasitology)</term>
<term>Elephantiasis, Filarial (prevention & control)</term>
<term>Female</term>
<term>Geography</term>
<term>Humans</term>
<term>India (epidemiology)</term>
<term>Insect Vectors (parasitology)</term>
<term>Male</term>
<term>Microfilariae</term>
<term>Middle Aged</term>
<term>Prevalence</term>
<term>Wuchereria bancrofti (isolation & purification)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term>
<term>India</term>
</keywords>
<keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Culex</term>
<term>Elephantiasis, Filarial</term>
<term>Insect Vectors</term>
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<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis, Filarial</term>
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<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Animals</term>
<term>Child</term>
<term>Disease Eradication</term>
<term>Female</term>
<term>Geography</term>
<term>Humans</term>
<term>Male</term>
<term>Microfilariae</term>
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<front><div type="abstract" xml:lang="en">This study was undertaken to determine the prevalence of filarial infection in the districts of Madhya Pradesh, which were classified as non-endemic by the national program for control of filariasis. These districts showed evidence of clinical symptoms related to filariasis. To confirm the presence of filariasis, night blood surveys and entomological surveys were carried out to detect microfilaria in humans and filarial infection in vectors.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27413817</PMID>
<DateCreated><Year>2016</Year>
<Month>09</Month>
<Day>28</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>04</Month>
<Day>06</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>08</Month>
<Day>17</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2047-7732</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>110</Volume>
<Issue>4-5</Issue>
<PubDate><MedlineDate>2016 Jun-Jul</MedlineDate>
</PubDate>
</JournalIssue>
<Title>Pathogens and global health</Title>
<ISOAbbreviation>Pathog Glob Health</ISOAbbreviation>
</Journal>
<ArticleTitle>Mapping is a prerequisite for elimination of filariasis and effective targeting of filarial 'hot spots'.</ArticleTitle>
<Pagination><MedlinePgn>157-63</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1080/20477724.2016.1205302</ELocationID>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">This study was undertaken to determine the prevalence of filarial infection in the districts of Madhya Pradesh, which were classified as non-endemic by the national program for control of filariasis. These districts showed evidence of clinical symptoms related to filariasis. To confirm the presence of filariasis, night blood surveys and entomological surveys were carried out to detect microfilaria in humans and filarial infection in vectors.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">For microfilaria surveys, thick blood smears were prepared by taking 60 μL of blood between 8.00 and 11.00 pm and examined under a microscope. Vectors Culex quinquefasciatus were dissected for the filarial infection from the affected villages of four non-endemic districts.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Prevalence of microfilaria in the four districts ranged from 3.8% in district Shivpuri to 11.2% in district Bhind (overall mf rate 6.9%, 95% CI = 6.2-7.7). Infection and infectivity rates among vectors were recorded from three districts which varied from 2 to 13% and from 1.3 to 3.6%.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The study confirmed the presence of circulating microfilaria in non-endemic population of four districts, which has significant public health implications. To assess filarial endemicity and hot spots, precise filarial risk mapping using new efficient diagnostic tools is needed to reinforce and extend the strategy in other areas to achieve elimination of lymphatic filariasis.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Chand</LastName>
<ForeName>Gyan</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kaushal</LastName>
<ForeName>Laxman Singh</ForeName>
<Initials>LS</Initials>
<AffiliationInfo><Affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Choudhari</LastName>
<ForeName>Narendra Kumar</ForeName>
<Initials>NK</Initials>
<AffiliationInfo><Affiliation>a Department of Public Health Entomology , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Singh</LastName>
<ForeName>Neeru</ForeName>
<Initials>N</Initials>
<AffiliationInfo><Affiliation>b Department of Epidemiology and Vector Control , National Institute for Research in Tribal Health (ICMR) , Jabalpur , India.</Affiliation>
</AffiliationInfo>
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<Language>eng</Language>
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<CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Wkly Epidemiol Rec. 2004 Nov 19;79(47):417-24</RefSource>
<PMID Version="1">15595525</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2013 Jul;89(1):11-5</RefSource>
<PMID Version="1">23690552</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2009 Mar;103(3):262-5</RefSource>
<PMID Version="1">18809193</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Filaria J. 2003 Jul 21;2(1):12</RefSource>
<PMID Version="1">12914666</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Commun Dis. 1996 Dec;28(4):304-7</RefSource>
<PMID Version="1">9057457</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 2005 Jun;121(6):771-5</RefSource>
<PMID Version="1">16037622</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet Infect Dis. 2005 Jan;5(1):4-5</RefSource>
<PMID Version="1">15620551</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2000 Sep;94(6):591-606</RefSource>
<PMID Version="1">11064761</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 2013 May;137(5):881-94</RefSource>
<PMID Version="1">23760372</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3319</RefSource>
<PMID Version="1">25412180</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasit Vectors. 2015 Jul 15;8:369</RefSource>
<PMID Version="1">26168919</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Negl Trop Dis. 2012;6(11):e1926</RefSource>
<PMID Version="1">23209865</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Wkly Epidemiol Rec. 2013 Sep 13;88(37):389-99</RefSource>
<PMID Version="1">24073461</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 1980 May;71:725-33</RefSource>
<PMID Version="1">7409867</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet Infect Dis. 2015 Apr;15(4):380</RefSource>
<PMID Version="1">25809895</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Adv Parasitol. 2006;61:395-441</RefSource>
<PMID Version="1">16735170</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2011 Aug;105(8):431-7</RefSource>
<PMID Version="1">21601901</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Vector Borne Dis. 2008 Dec;45(4):313-20</RefSource>
<PMID Version="1">19248659</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2011 Feb;105(2):109-14</RefSource>
<PMID Version="1">21122883</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Adv Parasitol. 2000;47:245-88</RefSource>
<PMID Version="1">10997209</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Ann Trop Med Parasitol. 2002 Dec;96 Suppl 2:S15-40</RefSource>
<PMID Version="1">12630391</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Filaria J. 2003 Mar 19;2(1):7</RefSource>
<PMID Version="1">12694630</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>J Postgrad Med. 2010 Jul-Sep;56(3):232-8</RefSource>
<PMID Version="1">20739779</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Parasitology. 2014 Dec;141(14 ):1912-7</RefSource>
<PMID Version="1">25225828</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Trans R Soc Trop Med Hyg. 2013 Jul;107(7):462-4</RefSource>
<PMID Version="1">23687107</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Bull World Health Organ. 1997;75(6):491-503</RefSource>
<PMID Version="1">9509621</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Vector Borne Zoonotic Dis. 2013 Sep;13(9):657-65</RefSource>
<PMID Version="1">23808973</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Indian J Med Res. 1977 Aug;66(2):200-15</RefSource>
<PMID Version="1">336534</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>World Health Organ Tech Rep Ser. 1984;702:3-112</RefSource>
<PMID Version="1">6435317</PMID>
</CommentsCorrections>
</CommentsCorrectionsList>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D005843" MajorTopicYN="N">Geography</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D007194" MajorTopicYN="N">India</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
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<MeshHeading><DescriptorName UI="D007303" MajorTopicYN="N">Insect Vectors</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008842" MajorTopicYN="N">Microfilariae</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName>
<QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName>
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<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
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</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Filaria elimination</Keyword>
<Keyword MajorTopicYN="N">Lymphatic filariasis</Keyword>
<Keyword MajorTopicYN="N">Mass drug administration</Keyword>
<Keyword MajorTopicYN="N">Wuchereria bancrofti</Keyword>
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