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Bronchiectasis in yellow nail syndrome.

Identifieur interne : 000659 ( PubMed/Corpus ); précédent : 000658; suivant : 000660

Bronchiectasis in yellow nail syndrome.

Auteurs : Georgia Woodfield ; Mitzi Nisbet ; Joe Jacob ; Wing Mok ; Michael R. Loebinger ; David M. Hansell ; Athol U. Wells ; Robert Wilson

Source :

RBID : pubmed:27551950

Abstract

Yellow nail syndrome (YNS) is a rare and poorly described disease process. In this case-control study, clinical features and findings on HRCT were compared with idiopathic bronchiectasis (IBx).

DOI: 10.1111/resp.12866
PubMed: 27551950

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pubmed:27551950

Le document en format XML

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<name sortKey="Woodfield, Georgia" sort="Woodfield, Georgia" uniqKey="Woodfield G" first="Georgia" last="Woodfield">Georgia Woodfield</name>
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<nlm:affiliation>Host Defence Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Nisbet, Mitzi" sort="Nisbet, Mitzi" uniqKey="Nisbet M" first="Mitzi" last="Nisbet">Mitzi Nisbet</name>
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<nlm:affiliation>Host Defence Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Jacob, Joe" sort="Jacob, Joe" uniqKey="Jacob J" first="Joe" last="Jacob">Joe Jacob</name>
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<nlm:affiliation>Radiology Department, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Mok, Wing" sort="Mok, Wing" uniqKey="Mok W" first="Wing" last="Mok">Wing Mok</name>
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<nlm:affiliation>Radiology Department, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Loebinger, Michael R" sort="Loebinger, Michael R" uniqKey="Loebinger M" first="Michael R" last="Loebinger">Michael R. Loebinger</name>
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<nlm:affiliation>Host Defence Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Hansell, David M" sort="Hansell, David M" uniqKey="Hansell D" first="David M" last="Hansell">David M. Hansell</name>
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<nlm:affiliation>Radiology Department, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Wells, Athol U" sort="Wells, Athol U" uniqKey="Wells A" first="Athol U" last="Wells">Athol U. Wells</name>
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<nlm:affiliation>Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Wilson, Robert" sort="Wilson, Robert" uniqKey="Wilson R" first="Robert" last="Wilson">Robert Wilson</name>
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<name sortKey="Jacob, Joe" sort="Jacob, Joe" uniqKey="Jacob J" first="Joe" last="Jacob">Joe Jacob</name>
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<name sortKey="Mok, Wing" sort="Mok, Wing" uniqKey="Mok W" first="Wing" last="Mok">Wing Mok</name>
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<name sortKey="Loebinger, Michael R" sort="Loebinger, Michael R" uniqKey="Loebinger M" first="Michael R" last="Loebinger">Michael R. Loebinger</name>
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<nlm:affiliation>Host Defence Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Hansell, David M" sort="Hansell, David M" uniqKey="Hansell D" first="David M" last="Hansell">David M. Hansell</name>
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<nlm:affiliation>Radiology Department, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Wells, Athol U" sort="Wells, Athol U" uniqKey="Wells A" first="Athol U" last="Wells">Athol U. Wells</name>
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<nlm:affiliation>Interstitial Lung Disease Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<name sortKey="Wilson, Robert" sort="Wilson, Robert" uniqKey="Wilson R" first="Robert" last="Wilson">Robert Wilson</name>
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<nlm:affiliation>Host Defence Unit, Royal Brompton Hospital, London, UK.</nlm:affiliation>
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<title level="j">Respirology (Carlton, Vic.)</title>
<idno type="eISSN">1440-1843</idno>
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<div type="abstract" xml:lang="en">Yellow nail syndrome (YNS) is a rare and poorly described disease process. In this case-control study, clinical features and findings on HRCT were compared with idiopathic bronchiectasis (IBx).</div>
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<Year>2016</Year>
<Month>08</Month>
<Day>23</Day>
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<Year>2016</Year>
<Month>12</Month>
<Day>16</Day>
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<ISSN IssnType="Electronic">1440-1843</ISSN>
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<Volume>22</Volume>
<Issue>1</Issue>
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<Year>2017</Year>
<Month>Jan</Month>
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<Title>Respirology (Carlton, Vic.)</Title>
<ISOAbbreviation>Respirology</ISOAbbreviation>
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<ArticleTitle>Bronchiectasis in yellow nail syndrome.</ArticleTitle>
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<MedlinePgn>101-107</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1111/resp.12866</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND AND OBJECTIVE" NlmCategory="OBJECTIVE">Yellow nail syndrome (YNS) is a rare and poorly described disease process. In this case-control study, clinical features and findings on HRCT were compared with idiopathic bronchiectasis (IBx).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A review of all patients attending an adult bronchiectasis clinic between 2007 and 2013 identified 25 YNS patients. IBx patients were matched in a 2:1 ratio for age, duration of symptoms and gender.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Median age of onset was 53 years. There were 12 male and 23 Caucasian YNS patients. Respiratory manifestations included chronic productive cough (100%), chronic rhinosinusitis (88%), pleural effusions (20%) and lymphoedema (12%). Chest symptoms preceded yellow nails in the majority (68%). Abnormal nails persisted at follow-up in 23 of 25 patients but improved in 14. In both disorders, there was symmetrical, predominantly lower lobe bronchiectasis on HRCT. Extent (P = 0.04), severity (P = 0.03) and bronchial wall thickness (P = 0.05) scores were lower in YNS, with less upper and middle lobe disease. Multivariate analysis showed an independent association with increased mucus plugging in YNS. There was a similar prevalence of Pseudomonas aeruginosa infection and mild lung function abnormalities.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Bronchiectasis in YNS is less severe than IBx but is associated with increased mucus plugging, onset is in middle age and there is no female predominance. Treatment targeted at improved secretion clearance may improve both chest and nail symptoms, with consideration of long-term macrolide antibiotics.</AbstractText>
<CopyrightInformation>© 2016 Asian Pacific Society of Respirology.</CopyrightInformation>
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<Keyword MajorTopicYN="N">pleural effusion</Keyword>
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