LymphedemaV1, PubMed, Corpus, bibRecord, 000474

Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.

Identifieur interne : 000474 ( PubMed/Corpus ); précédent : 000473; suivant : 000475

Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.

Auteurs : Ting-Yuan Hsu ; Chun-Chen Lin ; Ming-Dar Lee ; Brian Pin-Hsuan Chang ; Jeng-Daw Tsai

Source :

Pediatrics [ 1098-4275 ] ; 2017.

RBID : pubmed:27940507

English descriptors

KwdEn :
- Bronchiectasis (chemically induced), Bronchiectasis (diagnosis), Child, Diagnosis, Differential, Female, Humans, Maxillary Sinusitis (chemically induced), Maxillary Sinusitis (diagnosis), Nails (chemistry), Titanium (analysis), Titanium (toxicity), Toothpastes (chemistry), Toothpastes (toxicity), Yellow Nail Syndrome (chemically induced), Yellow Nail Syndrome (diagnosis).
MESH :
- chemical , analysis : Titanium.
- chemically induced : Bronchiectasis, Maxillary Sinusitis, Yellow Nail Syndrome.
- chemistry : Nails, Toothpastes.
- diagnosis : Bronchiectasis, Maxillary Sinusitis, Yellow Nail Syndrome.
- chemical , toxicity : Titanium, Toothpastes.
- Child, Diagnosis, Differential, Female, Humans.

Abstract

Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence. This patient's titanium exposure may have come from her habit of swallowing children's toothpaste. With meticulous avoidance of swallowing toothpaste, she had amelioration of her yellow nail discoloration as well as diminution of her respiratory symptoms. We reevaluated her nail clippings for titanium 3 years later, and no titanium was detected. This observation suggests that avoiding titanium exposure could alleviate the symptoms of YNS. This is the first report of YNS in a pediatric patient that demonstrates a relationship between YNS and titanium. We review the previous reports of pediatric patients with YNS.

DOI: 10.1542/peds.2016-0546
PubMed: 27940507

Links to Exploration step

pubmed:27940507

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.</title>
<author><name sortKey="Hsu, Ting Yuan" sort="Hsu, Ting Yuan" uniqKey="Hsu T" first="Ting-Yuan" last="Hsu">Ting-Yuan Hsu</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lin, Chun Chen" sort="Lin, Chun Chen" uniqKey="Lin C" first="Chun-Chen" last="Lin">Chun-Chen Lin</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lee, Ming Dar" sort="Lee, Ming Dar" uniqKey="Lee M" first="Ming-Dar" last="Lee">Ming-Dar Lee</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chang, Brian Pin Hsuan" sort="Chang, Brian Pin Hsuan" uniqKey="Chang B" first="Brian Pin-Hsuan" last="Chang">Brian Pin-Hsuan Chang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tsai, Jeng Daw" sort="Tsai, Jeng Daw" uniqKey="Tsai J" first="Jeng-Daw" last="Tsai">Jeng-Daw Tsai</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan; tsaijd@yahoo.com.tw.</nlm:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:27940507</idno>
<idno type="pmid">27940507</idno>
<idno type="doi">10.1542/peds.2016-0546</idno>
<idno type="wicri:Area/PubMed/Corpus">000474</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000474</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.</title>
<author><name sortKey="Hsu, Ting Yuan" sort="Hsu, Ting Yuan" uniqKey="Hsu T" first="Ting-Yuan" last="Hsu">Ting-Yuan Hsu</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lin, Chun Chen" sort="Lin, Chun Chen" uniqKey="Lin C" first="Chun-Chen" last="Lin">Chun-Chen Lin</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Lee, Ming Dar" sort="Lee, Ming Dar" uniqKey="Lee M" first="Ming-Dar" last="Lee">Ming-Dar Lee</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Chang, Brian Pin Hsuan" sort="Chang, Brian Pin Hsuan" uniqKey="Chang B" first="Brian Pin-Hsuan" last="Chang">Brian Pin-Hsuan Chang</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Tsai, Jeng Daw" sort="Tsai, Jeng Daw" uniqKey="Tsai J" first="Jeng-Daw" last="Tsai">Jeng-Daw Tsai</name>
<affiliation><nlm:affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan; tsaijd@yahoo.com.tw.</nlm:affiliation>
</affiliation>
</author>
</analytic>
<series><title level="j">Pediatrics</title>
<idno type="eISSN">1098-4275</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bronchiectasis (chemically induced)</term>
<term>Bronchiectasis (diagnosis)</term>
<term>Child</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
<term>Maxillary Sinusitis (chemically induced)</term>
<term>Maxillary Sinusitis (diagnosis)</term>
<term>Nails (chemistry)</term>
<term>Titanium (analysis)</term>
<term>Titanium (toxicity)</term>
<term>Toothpastes (chemistry)</term>
<term>Toothpastes (toxicity)</term>
<term>Yellow Nail Syndrome (chemically induced)</term>
<term>Yellow Nail Syndrome (diagnosis)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Titanium</term>
</keywords>
<keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Bronchiectasis</term>
<term>Maxillary Sinusitis</term>
<term>Yellow Nail Syndrome</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nails</term>
<term>Toothpastes</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Bronchiectasis</term>
<term>Maxillary Sinusitis</term>
<term>Yellow Nail Syndrome</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Titanium</term>
<term>Toothpastes</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Child</term>
<term>Diagnosis, Differential</term>
<term>Female</term>
<term>Humans</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence. This patient's titanium exposure may have come from her habit of swallowing children's toothpaste. With meticulous avoidance of swallowing toothpaste, she had amelioration of her yellow nail discoloration as well as diminution of her respiratory symptoms. We reevaluated her nail clippings for titanium 3 years later, and no titanium was detected. This observation suggests that avoiding titanium exposure could alleviate the symptoms of YNS. This is the first report of YNS in a pediatric patient that demonstrates a relationship between YNS and titanium. We review the previous reports of pediatric patients with YNS.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27940507</PMID>
<DateCreated><Year>2016</Year>
<Month>12</Month>
<Day>12</Day>
</DateCreated>
<DateCompleted><Year>2017</Year>
<Month>06</Month>
<Day>26</Day>
</DateCompleted>
<DateRevised><Year>2017</Year>
<Month>06</Month>
<Day>26</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1098-4275</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>139</Volume>
<Issue>1</Issue>
<PubDate><Year>2017</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>Pediatrics</Title>
<ISOAbbreviation>Pediatrics</ISOAbbreviation>
</Journal>
<ArticleTitle>Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.</ArticleTitle>
<ELocationID EIdType="pii" ValidYN="Y">e20160546</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1542/peds.2016-0546</ELocationID>
<Abstract><AbstractText>Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence. This patient's titanium exposure may have come from her habit of swallowing children's toothpaste. With meticulous avoidance of swallowing toothpaste, she had amelioration of her yellow nail discoloration as well as diminution of her respiratory symptoms. We reevaluated her nail clippings for titanium 3 years later, and no titanium was detected. This observation suggests that avoiding titanium exposure could alleviate the symptoms of YNS. This is the first report of YNS in a pediatric patient that demonstrates a relationship between YNS and titanium. We review the previous reports of pediatric patients with YNS.</AbstractText>
<CopyrightInformation>Copyright © 2017 by the American Academy of Pediatrics.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hsu</LastName>
<ForeName>Ting-Yuan</ForeName>
<Initials>TY</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lin</LastName>
<ForeName>Chun-Chen</ForeName>
<Initials>CC</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine, MacKay Medical College, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>MacKay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Lee</LastName>
<ForeName>Ming-Dar</ForeName>
<Initials>MD</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine, MacKay Medical College, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chang</LastName>
<ForeName>Brian Pin-Hsuan</ForeName>
<Initials>BP</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine, MacKay Medical College, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan; and.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Tsai</LastName>
<ForeName>Jeng-Daw</ForeName>
<Initials>JD</Initials>
<AffiliationInfo><Affiliation>Department of Pediatrics, MacKay Children's Hospital, Taipei, Taiwan; tsaijd@yahoo.com.tw.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Medicine, MacKay Medical College, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan; and.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>12</Month>
<Day>07</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Pediatrics</MedlineTA>
<NlmUniqueID>0376422</NlmUniqueID>
<ISSNLinking>0031-4005</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D014100">Toothpastes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>15FIX9V2JP</RegistryNumber>
<NameOfSubstance UI="C009495">titanium dioxide</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>D1JT611TNE</RegistryNumber>
<NameOfSubstance UI="D014025">Titanium</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>AIM</CitationSubset>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D001987" MajorTopicYN="N">Bronchiectasis</DescriptorName>
<QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015523" MajorTopicYN="N">Maxillary Sinusitis</DescriptorName>
<QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D009262" MajorTopicYN="N">Nails</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014025" MajorTopicYN="N">Titanium</DescriptorName>
<QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName>
<QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014100" MajorTopicYN="N">Toothpastes</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="Y">chemistry</QualifierName>
<QualifierName UI="Q000633" MajorTopicYN="Y">toxicity</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D056684" MajorTopicYN="N">Yellow Nail Syndrome</DescriptorName>
<QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>08</Month>
<Day>31</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>12</Month>
<Day>13</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2017</Year>
<Month>6</Month>
<Day>27</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>12</Month>
<Day>13</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27940507</ArticleId>
<ArticleId IdType="pii">peds.2016-0546</ArticleId>
<ArticleId IdType="doi">10.1542/peds.2016-0546</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000474 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000474 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PubMed
   |étape=   Corpus
   |type=    RBID
   |clé=     pubmed:27940507
   |texte=   Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i   -Sk "pubmed:27940507" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le lymphœdème

Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.

Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki