Treatment Preferences for Routine Lymphadenectomy Versus No Lymphadenectomy in Early-Stage Endometrial Cancer.
Identifieur interne : 000451 ( PubMed/Corpus ); précédent : 000450; suivant : 000452Treatment Preferences for Routine Lymphadenectomy Versus No Lymphadenectomy in Early-Stage Endometrial Cancer.
Auteurs : Jung-Yun Lee ; Kyunghoon Kim ; Yun Shin Lee ; Hyo Young Kim ; Eun Ji Nam ; Sunghoon Kim ; Sang Wun Kim ; Jae Weon Kim ; Young Tae KimSource :
- Annals of surgical oncology [ 1534-4681 ] ; 2017.
Abstract
Debate on the value of lymphadenectomy continues in endometrial cancer. The aim of this study was to investigate patient and clinician preferences for routine lymphadenectomy versus no lymphadenectomy in the surgical management of endometrial cancer.
DOI: 10.1245/s10434-016-5729-7
PubMed: 28000075
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Treatment Preferences for Routine Lymphadenectomy Versus No Lymphadenectomy in Early-Stage Endometrial Cancer.</title><author><name sortKey="Lee, Jung Yun" sort="Lee, Jung Yun" uniqKey="Lee J" first="Jung-Yun" last="Lee">Jung-Yun Lee</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Kyunghoon" sort="Kim, Kyunghoon" uniqKey="Kim K" first="Kyunghoon" last="Kim">Kyunghoon Kim</name><affiliation><nlm:affiliation>Korea Information Society Development Institute, Seoul, Chungcheongbuk-do, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Yun Shin" sort="Lee, Yun Shin" uniqKey="Lee Y" first="Yun Shin" last="Lee">Yun Shin Lee</name><affiliation><nlm:affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Hyo Young" sort="Kim, Hyo Young" uniqKey="Kim H" first="Hyo Young" last="Kim">Hyo Young Kim</name><affiliation><nlm:affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Nam, Eun Ji" sort="Nam, Eun Ji" uniqKey="Nam E" first="Eun Ji" last="Nam">Eun Ji Nam</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sunghoon" sort="Kim, Sunghoon" uniqKey="Kim S" first="Sunghoon" last="Kim">Sunghoon Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sang Wun" sort="Kim, Sang Wun" uniqKey="Kim S" first="Sang Wun" last="Kim">Sang Wun Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jae Weon" sort="Kim, Jae Weon" uniqKey="Kim J" first="Jae Weon" last="Kim">Jae Weon Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Young Tae" sort="Kim, Young Tae" uniqKey="Kim Y" first="Young Tae" last="Kim">Young Tae Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea. ytkchoi@yuhs.ac.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28000075</idno><idno type="pmid">28000075</idno><idno type="doi">10.1245/s10434-016-5729-7</idno><idno type="wicri:Area/PubMed/Corpus">000451</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000451</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Treatment Preferences for Routine Lymphadenectomy Versus No Lymphadenectomy in Early-Stage Endometrial Cancer.</title><author><name sortKey="Lee, Jung Yun" sort="Lee, Jung Yun" uniqKey="Lee J" first="Jung-Yun" last="Lee">Jung-Yun Lee</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Kyunghoon" sort="Kim, Kyunghoon" uniqKey="Kim K" first="Kyunghoon" last="Kim">Kyunghoon Kim</name><affiliation><nlm:affiliation>Korea Information Society Development Institute, Seoul, Chungcheongbuk-do, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Lee, Yun Shin" sort="Lee, Yun Shin" uniqKey="Lee Y" first="Yun Shin" last="Lee">Yun Shin Lee</name><affiliation><nlm:affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Hyo Young" sort="Kim, Hyo Young" uniqKey="Kim H" first="Hyo Young" last="Kim">Hyo Young Kim</name><affiliation><nlm:affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Nam, Eun Ji" sort="Nam, Eun Ji" uniqKey="Nam E" first="Eun Ji" last="Nam">Eun Ji Nam</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sunghoon" sort="Kim, Sunghoon" uniqKey="Kim S" first="Sunghoon" last="Kim">Sunghoon Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Sang Wun" sort="Kim, Sang Wun" uniqKey="Kim S" first="Sang Wun" last="Kim">Sang Wun Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Jae Weon" sort="Kim, Jae Weon" uniqKey="Kim J" first="Jae Weon" last="Kim">Jae Weon Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.</nlm:affiliation></affiliation></author><author><name sortKey="Kim, Young Tae" sort="Kim, Young Tae" uniqKey="Kim Y" first="Young Tae" last="Kim">Young Tae Kim</name><affiliation><nlm:affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea. ytkchoi@yuhs.ac.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Annals of surgical oncology</title><idno type="eISSN">1534-4681</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Debate on the value of lymphadenectomy continues in endometrial cancer. The aim of this study was to investigate patient and clinician preferences for routine lymphadenectomy versus no lymphadenectomy in the surgical management of endometrial cancer.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28000075</PMID><DateCreated><Year>2016</Year><Month>12</Month><Day>21</Day></DateCreated><DateRevised><Year>2017</Year><Month>03</Month><Day>31</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1534-4681</ISSN><JournalIssue CitedMedium="Internet"><Volume>24</Volume><Issue>5</Issue><PubDate><Year>2017</Year><Month>May</Month></PubDate></JournalIssue><Title>Annals of surgical oncology</Title><ISOAbbreviation>Ann. Surg. Oncol.</ISOAbbreviation></Journal><ArticleTitle>Treatment Preferences for Routine Lymphadenectomy Versus No Lymphadenectomy in Early-Stage Endometrial Cancer.</ArticleTitle><Pagination><MedlinePgn>1336-1342</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1245/s10434-016-5729-7</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Debate on the value of lymphadenectomy continues in endometrial cancer. The aim of this study was to investigate patient and clinician preferences for routine lymphadenectomy versus no lymphadenectomy in the surgical management of endometrial cancer.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A discrete choice experiment and trade-off question were designed and distributed to 103 endometrial cancer patients and 90 gynecologic oncologists. Participant preferences were quantified with regression analysis using scenarios based on three attributes: 5-year progression-free survival and the rates of acute and chronic complication. A trade-off technique varying the risk of recurrence for no lymphadenectomy was used to quantify any additional risk of recurrence that these participants would accept to receive no lymphadenectomy instead of routine lymphadenectomy.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">On the basis of discrete choice experiment, the recurrence rate and lymphedema risk had a statistically significant impact on respondents' preference. The trade-off question showed that the median additional accepted risk of having no lymphadenectomy was 2.8% for gynecologic oncologists (0.5-14%) and 3.0% for patients (0.5-10%), but this difference was not significant (p = 0.620). Patients who were younger or had a higher education level or no history of delivery or shorter duration since diagnosis were prepared to accept higher additional risks of having no lymphadenectomy.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Our results show that the majority of endometrial cancer patients and clinicians will accept a small amount of recurrence risk to reduce the incidence of lymphedema. Regarding preference heterogeneity among patients, our results show that it is important for surgeons to take a patient-tailored approach when discussing surgical management.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Jung-Yun</ForeName><Initials>JY</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Kyunghoon</ForeName><Initials>K</Initials><AffiliationInfo><Affiliation>Korea Information Society Development Institute, Seoul, Chungcheongbuk-do, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Lee</LastName><ForeName>Yun Shin</ForeName><Initials>YS</Initials><AffiliationInfo><Affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Hyo Young</ForeName><Initials>HY</Initials><AffiliationInfo><Affiliation>KAIST College of Business, Korea Advanced Institute of Science and Technology, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nam</LastName><ForeName>Eun Ji</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sunghoon</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Sang Wun</ForeName><Initials>SW</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Jae Weon</ForeName><Initials>JW</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kim</LastName><ForeName>Young Tae</ForeName><Initials>YT</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Gynecology, Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Korea. ytkchoi@yuhs.ac.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>12</Month><Day>20</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Ann Surg Oncol</MedlineTA><NlmUniqueID>9420840</NlmUniqueID><ISSNLinking>1068-9265</ISSNLinking></MedlineJournalInfo></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year><Month>08</Month><Day>16</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2016</Year><Month>12</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2016</Year><Month>12</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2016</Year><Month>12</Month><Day>22</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28000075</ArticleId><ArticleId IdType="doi">10.1245/s10434-016-5729-7</ArticleId><ArticleId IdType="pii">10.1245/s10434-016-5729-7</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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