Preoperative irradiation, lymphadenectomy and 125iodine implant for patients with localized prostatic carcinoma: a correlation of implant dosimetry with clinical results.
Identifieur interne : 006435 ( PubMed/Checkpoint ); précédent : 006434; suivant : 006436Preoperative irradiation, lymphadenectomy and 125iodine implant for patients with localized prostatic carcinoma: a correlation of implant dosimetry with clinical results.
Auteurs : W U Shipley ; G. Kopelson ; D H Novack ; C C Ling ; S P Dretler ; G R ProutSource :
- The Journal of urology [ 0022-5347 ] ; 1980.
Descripteurs français
- KwdFr :
- Curiethérapie (effets indésirables), Dosimétrie en radiothérapie, Dysfonctionnement érectile (étiologie), Essaimage tumoral, Humains, Lymphadénectomie, Mâle, Pelvis, Radio-isotopes de l'iode (effets indésirables), Radio-isotopes de l'iode (usage thérapeutique), Récidive tumorale locale, Soins préopératoires, Troubles mictionnels (étiologie), Tumeurs de la prostate (), Études d'évaluation comme sujet, Études de suivi.
- MESH :
- effets indésirables : Curiethérapie, Radio-isotopes de l'iode.
- usage thérapeutique : Radio-isotopes de l'iode.
- étiologie : Dysfonctionnement érectile, Troubles mictionnels.
- Dosimétrie en radiothérapie, Essaimage tumoral, Humains, Lymphadénectomie, Mâle, Pelvis, Récidive tumorale locale, Soins préopératoires, Tumeurs de la prostate, Études d'évaluation comme sujet, Études de suivi.
English descriptors
- KwdEn :
- Brachytherapy (adverse effects), Erectile Dysfunction (etiology), Evaluation Studies as Topic, Follow-Up Studies, Humans, Iodine Radioisotopes (adverse effects), Iodine Radioisotopes (therapeutic use), Lymph Node Excision, Male, Neoplasm Recurrence, Local, Neoplasm Seeding, Pelvis, Preoperative Care, Prostatic Neoplasms (therapy), Radiotherapy Dosage, Urination Disorders (etiology).
- MESH :
- chemical , adverse effects : Iodine Radioisotopes.
- adverse effects : Brachytherapy.
- etiology : Erectile Dysfunction, Urination Disorders.
- chemical , therapeutic use : Iodine Radioisotopes.
- therapy : Prostatic Neoplasms.
- Evaluation Studies as Topic, Follow-Up Studies, Humans, Lymph Node Excision, Male, Neoplasm Recurrence, Local, Neoplasm Seeding, Pelvis, Preoperative Care, Radiotherapy Dosage.
Abstract
The 30 patients with clinically and surgically localized prostatic carcinoma who were selected for treatment by a short course of preoperative irradiation (1,050 rad), pelvic lymphadenectomy and 125iodine implant have been followed for 1 to 4 years. Perioperative morbidity (10 per cent), postimplant impotence (11 per cent), lymphedema (17 per cent), tumor recurrence (4 per cent) and distant metastasis (4 per cent) have been minimal to date. However, urinary irritative symptoms, which usually subsided in 6 to 9 months, occurred in half of the patients and correlated with implant volume. Total dose and total dose per unit of implanted activity were calculated. Of the various implant parameters evaluated implant dose homogeneity has corrrelated with the rate of tumor regression.
PubMed: 7452792
Affiliations:
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pubmed:7452792Le document en format XML
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<author><name sortKey="Kopelson, G" sort="Kopelson, G" uniqKey="Kopelson G" first="G" last="Kopelson">G. Kopelson</name>
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<author><name sortKey="Novack, D H" sort="Novack, D H" uniqKey="Novack D" first="D H" last="Novack">D H Novack</name>
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<author><name sortKey="Ling, C C" sort="Ling, C C" uniqKey="Ling C" first="C C" last="Ling">C C Ling</name>
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<author><name sortKey="Dretler, S P" sort="Dretler, S P" uniqKey="Dretler S" first="S P" last="Dretler">S P Dretler</name>
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<author><name sortKey="Prout, G R" sort="Prout, G R" uniqKey="Prout G" first="G R" last="Prout">G R Prout</name>
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<term>Erectile Dysfunction (etiology)</term>
<term>Evaluation Studies as Topic</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Iodine Radioisotopes (adverse effects)</term>
<term>Iodine Radioisotopes (therapeutic use)</term>
<term>Lymph Node Excision</term>
<term>Male</term>
<term>Neoplasm Recurrence, Local</term>
<term>Neoplasm Seeding</term>
<term>Pelvis</term>
<term>Preoperative Care</term>
<term>Prostatic Neoplasms (therapy)</term>
<term>Radiotherapy Dosage</term>
<term>Urination Disorders (etiology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Curiethérapie (effets indésirables)</term>
<term>Dosimétrie en radiothérapie</term>
<term>Dysfonctionnement érectile (étiologie)</term>
<term>Essaimage tumoral</term>
<term>Humains</term>
<term>Lymphadénectomie</term>
<term>Mâle</term>
<term>Pelvis</term>
<term>Radio-isotopes de l'iode (effets indésirables)</term>
<term>Radio-isotopes de l'iode (usage thérapeutique)</term>
<term>Récidive tumorale locale</term>
<term>Soins préopératoires</term>
<term>Troubles mictionnels (étiologie)</term>
<term>Tumeurs de la prostate ()</term>
<term>Études d'évaluation comme sujet</term>
<term>Études de suivi</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Iodine Radioisotopes</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Brachytherapy</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Curiethérapie</term>
<term>Radio-isotopes de l'iode</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Erectile Dysfunction</term>
<term>Urination Disorders</term>
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<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Iodine Radioisotopes</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Radio-isotopes de l'iode</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Dysfonctionnement érectile</term>
<term>Troubles mictionnels</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Evaluation Studies as Topic</term>
<term>Follow-Up Studies</term>
<term>Humans</term>
<term>Lymph Node Excision</term>
<term>Male</term>
<term>Neoplasm Recurrence, Local</term>
<term>Neoplasm Seeding</term>
<term>Pelvis</term>
<term>Preoperative Care</term>
<term>Radiotherapy Dosage</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Dosimétrie en radiothérapie</term>
<term>Essaimage tumoral</term>
<term>Humains</term>
<term>Lymphadénectomie</term>
<term>Mâle</term>
<term>Pelvis</term>
<term>Récidive tumorale locale</term>
<term>Soins préopératoires</term>
<term>Tumeurs de la prostate</term>
<term>Études d'évaluation comme sujet</term>
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<front><div type="abstract" xml:lang="en">The 30 patients with clinically and surgically localized prostatic carcinoma who were selected for treatment by a short course of preoperative irradiation (1,050 rad), pelvic lymphadenectomy and 125iodine implant have been followed for 1 to 4 years. Perioperative morbidity (10 per cent), postimplant impotence (11 per cent), lymphedema (17 per cent), tumor recurrence (4 per cent) and distant metastasis (4 per cent) have been minimal to date. However, urinary irritative symptoms, which usually subsided in 6 to 9 months, occurred in half of the patients and correlated with implant volume. Total dose and total dose per unit of implanted activity were calculated. Of the various implant parameters evaluated implant dose homogeneity has corrrelated with the rate of tumor regression.</div>
</front>
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<Title>The Journal of urology</Title>
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<ArticleTitle>Preoperative irradiation, lymphadenectomy and 125iodine implant for patients with localized prostatic carcinoma: a correlation of implant dosimetry with clinical results.</ArticleTitle>
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<Abstract><AbstractText>The 30 patients with clinically and surgically localized prostatic carcinoma who were selected for treatment by a short course of preoperative irradiation (1,050 rad), pelvic lymphadenectomy and 125iodine implant have been followed for 1 to 4 years. Perioperative morbidity (10 per cent), postimplant impotence (11 per cent), lymphedema (17 per cent), tumor recurrence (4 per cent) and distant metastasis (4 per cent) have been minimal to date. However, urinary irritative symptoms, which usually subsided in 6 to 9 months, occurred in half of the patients and correlated with implant volume. Total dose and total dose per unit of implanted activity were calculated. Of the various implant parameters evaluated implant dose homogeneity has corrrelated with the rate of tumor regression.</AbstractText>
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