Brugia pahangi: stage-specific antigens on microfilariae detected by serum from infected jirds or by monoclonal antibodies.
Identifieur interne : 005D56 ( PubMed/Checkpoint ); précédent : 005D55; suivant : 005D57Brugia pahangi: stage-specific antigens on microfilariae detected by serum from infected jirds or by monoclonal antibodies.
Auteurs : M. Tomisato ; H. Nariuchi ; J. Ueno ; S. Nogami ; H. Tanaka ; Y. Aoki ; Y. NakajimaSource :
- Experimental parasitology [ 0014-4894 ] ; 1986.
Descripteurs français
- KwdFr :
- Animaux, Anticorps (analyse), Anticorps monoclonaux (immunologie), Antigènes d'helminthe (analyse), Antigènes d'helminthe (immunologie), Brugia (croissance et développement), Brugia (immunologie), Femelle, Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Gerbillinae, Mâle, Réactions croisées, Spécificité d'espèce, Spécificité des anticorps, Techniques immunoenzymatiques, Épitopes (immunologie).
- MESH :
- analyse : Anticorps, Antigènes d'helminthe.
- croissance et développement : Brugia.
- immunologie : Anticorps monoclonaux, Antigènes d'helminthe, Brugia, Filariose lymphatique, Épitopes.
- parasitologie : Filariose lymphatique.
- Animaux, Femelle, Gerbillinae, Mâle, Réactions croisées, Spécificité d'espèce, Spécificité des anticorps, Techniques immunoenzymatiques.
English descriptors
- KwdEn :
- Animals, Antibodies (analysis), Antibodies, Monoclonal (immunology), Antibody Specificity, Antigens, Helminth (analysis), Antigens, Helminth (immunology), Brugia (growth & development), Brugia (immunology), Cross Reactions, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Epitopes (immunology), Female, Gerbillinae, Immunoenzyme Techniques, Male, Species Specificity.
- MESH :
- chemical , analysis : Antibodies, Antigens, Helminth.
- chemical , immunology : Antibodies, Monoclonal, Antigens, Helminth, Epitopes.
- growth & development : Brugia.
- immunology : Brugia, Elephantiasis, Filarial.
- parasitology : Elephantiasis, Filarial.
- Animals, Antibody Specificity, Cross Reactions, Female, Gerbillinae, Immunoenzyme Techniques, Male, Species Specificity.
Abstract
Experiments were carried out to determine whether there are stage-specific antigens on microfilariae of Brugia pahangi, using sera from Mongolian jirds infected with B. pahangi and monoclonal antibodies against microfilariae of B. pahangi. These studies showed that microfilariae have both stage-specific and nonspecific antigens. The nonspecific antigens were also present on adult worms and on infective larvae. Among monoclonal antibodies, 6 out of 14 clones produced antibodies against the microfilarial stage-specific antigens, and 8 clones produced antibodies against nonspecific antigens. These monoclonal antibodies could not distinguish between adults, microfilariae, or infective larvae of B. malayi and B. pahangi.
PubMed: 2417880
Affiliations:
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Aoki</name></author><author><name sortKey="Nakajima, Y" sort="Nakajima, Y" uniqKey="Nakajima Y" first="Y" last="Nakajima">Y. Nakajima</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1986">1986</date><idno type="RBID">pubmed:2417880</idno><idno type="pmid">2417880</idno><idno type="wicri:Area/PubMed/Corpus">006641</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006641</idno><idno type="wicri:Area/PubMed/Curation">006641</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006641</idno><idno type="wicri:Area/PubMed/Checkpoint">006641</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">006641</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Brugia pahangi: stage-specific antigens on microfilariae detected by serum from infected jirds or by monoclonal antibodies.</title><author><name sortKey="Tomisato, M" sort="Tomisato, M" uniqKey="Tomisato M" first="M" last="Tomisato">M. Tomisato</name></author><author><name sortKey="Nariuchi, H" sort="Nariuchi, H" uniqKey="Nariuchi H" first="H" last="Nariuchi">H. Nariuchi</name></author><author><name sortKey="Ueno, J" sort="Ueno, J" uniqKey="Ueno J" first="J" last="Ueno">J. Ueno</name></author><author><name sortKey="Nogami, S" sort="Nogami, S" uniqKey="Nogami S" first="S" last="Nogami">S. Nogami</name></author><author><name sortKey="Tanaka, H" sort="Tanaka, H" uniqKey="Tanaka H" first="H" last="Tanaka">H. Tanaka</name></author><author><name sortKey="Aoki, Y" sort="Aoki, Y" uniqKey="Aoki Y" first="Y" last="Aoki">Y. Aoki</name></author><author><name sortKey="Nakajima, Y" sort="Nakajima, Y" uniqKey="Nakajima Y" first="Y" last="Nakajima">Y. 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These studies showed that microfilariae have both stage-specific and nonspecific antigens. The nonspecific antigens were also present on adult worms and on infective larvae. Among monoclonal antibodies, 6 out of 14 clones produced antibodies against the microfilarial stage-specific antigens, and 8 clones produced antibodies against nonspecific antigens. These monoclonal antibodies could not distinguish between adults, microfilariae, or infective larvae of B. malayi and B. pahangi.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2417880</PMID><DateCreated><Year>1986</Year><Month>03</Month><Day>12</Day></DateCreated><DateCompleted><Year>1986</Year><Month>03</Month><Day>12</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0014-4894</ISSN><JournalIssue CitedMedium="Print"><Volume>61</Volume><Issue>1</Issue><PubDate><Year>1986</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Experimental parasitology</Title><ISOAbbreviation>Exp. Parasitol.</ISOAbbreviation></Journal><ArticleTitle>Brugia pahangi: stage-specific antigens on microfilariae detected by serum from infected jirds or by monoclonal antibodies.</ArticleTitle><Pagination><MedlinePgn>18-25</MedlinePgn></Pagination><Abstract><AbstractText>Experiments were carried out to determine whether there are stage-specific antigens on microfilariae of Brugia pahangi, using sera from Mongolian jirds infected with B. pahangi and monoclonal antibodies against microfilariae of B. pahangi. These studies showed that microfilariae have both stage-specific and nonspecific antigens. The nonspecific antigens were also present on adult worms and on infective larvae. Among monoclonal antibodies, 6 out of 14 clones produced antibodies against the microfilarial stage-specific antigens, and 8 clones produced antibodies against nonspecific antigens. These monoclonal antibodies could not distinguish between adults, microfilariae, or infective larvae of B. malayi and B. pahangi.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tomisato</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Nariuchi</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Ueno</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Nogami</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Tanaka</LastName><ForeName>H</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Aoki</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Nakajima</LastName><ForeName>Y</ForeName><Initials>Y</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Exp Parasitol</MedlineTA><NlmUniqueID>0370713</NlmUniqueID><ISSNLinking>0014-4894</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000906">Antibodies</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000911">Antibodies, Monoclonal</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000939">Epitopes</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000906" MajorTopicYN="N">Antibodies</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000911" MajorTopicYN="N">Antibodies, Monoclonal</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000918" MajorTopicYN="N">Antibody Specificity</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000947" MajorTopicYN="N">Antigens, Helminth</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002009" MajorTopicYN="N">Brugia</DescriptorName><QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003429" MajorTopicYN="N">Cross Reactions</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000939" MajorTopicYN="N">Epitopes</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005849" MajorTopicYN="N">Gerbillinae</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007124" MajorTopicYN="N">Immunoenzyme Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013045" MajorTopicYN="N">Species Specificity</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1986</Year><Month>2</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1986</Year><Month>2</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1986</Year><Month>2</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2417880</ArticleId><ArticleId IdType="pii">0014-4894(86)90130-X</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Aoki, Y" sort="Aoki, Y" uniqKey="Aoki Y" first="Y" last="Aoki">Y. Aoki</name><name sortKey="Nakajima, Y" sort="Nakajima, Y" uniqKey="Nakajima Y" first="Y" last="Nakajima">Y. Nakajima</name><name sortKey="Nariuchi, H" sort="Nariuchi, H" uniqKey="Nariuchi H" first="H" last="Nariuchi">H. Nariuchi</name><name sortKey="Nogami, S" sort="Nogami, S" uniqKey="Nogami S" first="S" last="Nogami">S. Nogami</name><name sortKey="Tanaka, H" sort="Tanaka, H" uniqKey="Tanaka H" first="H" last="Tanaka">H. Tanaka</name><name sortKey="Tomisato, M" sort="Tomisato, M" uniqKey="Tomisato M" first="M" last="Tomisato">M. Tomisato</name><name sortKey="Ueno, J" sort="Ueno, J" uniqKey="Ueno J" first="J" last="Ueno">J. Ueno</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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