Intestinal lymphangiectasia and bilateral pleural effusions: effect of dietary therapy and surgical intervention on immunologic and pulmonary parameters.
Identifieur interne : 005D18 ( PubMed/Checkpoint ); précédent : 005D17; suivant : 005D19Intestinal lymphangiectasia and bilateral pleural effusions: effect of dietary therapy and surgical intervention on immunologic and pulmonary parameters.
Auteurs : L A Lester ; R M Rothberg ; H J Krantman ; D W ShermetaSource :
- The Journal of allergy and clinical immunology [ 0091-6749 ] ; 1986.
Descripteurs français
- KwdFr :
- Adolescent, Anticorps antibactériens (analyse), Entéropathie exsudative (), Humains, Immunité cellulaire, Immunoglobulines (analyse), Lymphangiectasie intestinale (), Lymphangiectasie intestinale (immunologie), Lymphocytes (), Poumon (physiopathologie), Test des rosettes, Épanchement pleural (), Épanchement pleural (immunologie), Épanchement pleural (physiopathologie).
- MESH :
- analyse : Anticorps antibactériens, Immunoglobulines.
- immunologie : Lymphangiectasie intestinale, Épanchement pleural.
- physiopathologie : Poumon, Épanchement pleural.
- Adolescent, Entéropathie exsudative, Humains, Immunité cellulaire, Lymphangiectasie intestinale, Lymphocytes, Test des rosettes, Épanchement pleural.
English descriptors
- KwdEn :
- Adolescent, Antibodies, Bacterial (analysis), Humans, Immunity, Cellular, Immunoglobulins (analysis), Lung (physiopathology), Lymphangiectasis, Intestinal (immunology), Lymphangiectasis, Intestinal (therapy), Lymphocytes (classification), Pleural Effusion (immunology), Pleural Effusion (physiopathology), Pleural Effusion (therapy), Protein-Losing Enteropathies (therapy), Rosette Formation.
- MESH :
- chemical , analysis : Antibodies, Bacterial, Immunoglobulins.
- classification : Lymphocytes.
- immunology : Lymphangiectasis, Intestinal, Pleural Effusion.
- physiopathology : Lung, Pleural Effusion.
- therapy : Lymphangiectasis, Intestinal, Pleural Effusion, Protein-Losing Enteropathies.
- Adolescent, Humans, Immunity, Cellular, Rosette Formation.
Abstract
This article describes the immunologic and pulmonary abnormalities and the chemical composition of pleural effusion fluid in a patient with intestinal lymphangiectasia as they are effected by therapeutic measures during a 7-year period. Lymphedema was first noticed in the patient at 3 years of age, and pleural effusions developed 7 years later. Thoracentesis demonstrated that the right pleural fluid was yellow, clear, and had the composition of lymph. The left pleural fluid was milky and had a higher triglyceride and lymphocyte content than the right pleural fluid. Complete removal of pleural fluid transiently increased total lung capacity to a maximum of 52% predicted. Strict dietary management with a low-fat and high-protein diet resulted in a transient partial reversal of circulating lymphopenia and low T cell concentration. This was accompanied by a decrease in lymphocyte and T cell concentration in the pleural fluid. Unstimulated mononuclear cells from pleural fluid synthesized increased amounts of DNA, and added mitogens or antigens further increased DNA synthesis. Dietary therapy had a minimal effect on this DNA synthesis. Despite circulating hypogammaglobulinemia, normal antibody activity was detected. The proportion of B cells in pleural fluid was greater than that in the circulation, and dietary therapy did not alter this difference. Pulmonary physiology improved during the initial 9-month period of diet therapy, but then the rate of fluid accumulation increased, causing respiratory compromise. Stability was achieved by a right-sided pleurodesis, followed 18 months later by a left pleurodesis with the addition of a shunt to provide internal lymph drainage.
PubMed: 3782656
Affiliations:
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scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphangiectasie intestinale</term><term>Épanchement pleural</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Lymphangiectasis, Intestinal</term><term>Pleural Effusion</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Poumon</term><term>Épanchement pleural</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Lung</term><term>Pleural Effusion</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphangiectasis, Intestinal</term><term>Pleural Effusion</term><term>Protein-Losing Enteropathies</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Humans</term><term>Immunity, Cellular</term><term>Rosette Formation</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Entéropathie exsudative</term><term>Humains</term><term>Immunité cellulaire</term><term>Lymphangiectasie intestinale</term><term>Lymphocytes</term><term>Test des rosettes</term><term>Épanchement pleural</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This article describes the immunologic and pulmonary abnormalities and the chemical composition of pleural effusion fluid in a patient with intestinal lymphangiectasia as they are effected by therapeutic measures during a 7-year period. Lymphedema was first noticed in the patient at 3 years of age, and pleural effusions developed 7 years later. Thoracentesis demonstrated that the right pleural fluid was yellow, clear, and had the composition of lymph. The left pleural fluid was milky and had a higher triglyceride and lymphocyte content than the right pleural fluid. Complete removal of pleural fluid transiently increased total lung capacity to a maximum of 52% predicted. Strict dietary management with a low-fat and high-protein diet resulted in a transient partial reversal of circulating lymphopenia and low T cell concentration. This was accompanied by a decrease in lymphocyte and T cell concentration in the pleural fluid. Unstimulated mononuclear cells from pleural fluid synthesized increased amounts of DNA, and added mitogens or antigens further increased DNA synthesis. Dietary therapy had a minimal effect on this DNA synthesis. Despite circulating hypogammaglobulinemia, normal antibody activity was detected. The proportion of B cells in pleural fluid was greater than that in the circulation, and dietary therapy did not alter this difference. Pulmonary physiology improved during the initial 9-month period of diet therapy, but then the rate of fluid accumulation increased, causing respiratory compromise. Stability was achieved by a right-sided pleurodesis, followed 18 months later by a left pleurodesis with the addition of a shunt to provide internal lymph drainage.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3782656</PMID><DateCreated><Year>1986</Year><Month>12</Month><Day>31</Day></DateCreated><DateCompleted><Year>1986</Year><Month>12</Month><Day>31</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0091-6749</ISSN><JournalIssue CitedMedium="Print"><Volume>78</Volume><Issue>5 Pt 1</Issue><PubDate><Year>1986</Year><Month>Nov</Month></PubDate></JournalIssue><Title>The Journal of allergy and clinical immunology</Title><ISOAbbreviation>J. Allergy Clin. Immunol.</ISOAbbreviation></Journal><ArticleTitle>Intestinal lymphangiectasia and bilateral pleural effusions: effect of dietary therapy and surgical intervention on immunologic and pulmonary parameters.</ArticleTitle><Pagination><MedlinePgn>891-7</MedlinePgn></Pagination><Abstract><AbstractText>This article describes the immunologic and pulmonary abnormalities and the chemical composition of pleural effusion fluid in a patient with intestinal lymphangiectasia as they are effected by therapeutic measures during a 7-year period. Lymphedema was first noticed in the patient at 3 years of age, and pleural effusions developed 7 years later. Thoracentesis demonstrated that the right pleural fluid was yellow, clear, and had the composition of lymph. The left pleural fluid was milky and had a higher triglyceride and lymphocyte content than the right pleural fluid. Complete removal of pleural fluid transiently increased total lung capacity to a maximum of 52% predicted. Strict dietary management with a low-fat and high-protein diet resulted in a transient partial reversal of circulating lymphopenia and low T cell concentration. This was accompanied by a decrease in lymphocyte and T cell concentration in the pleural fluid. Unstimulated mononuclear cells from pleural fluid synthesized increased amounts of DNA, and added mitogens or antigens further increased DNA synthesis. Dietary therapy had a minimal effect on this DNA synthesis. Despite circulating hypogammaglobulinemia, normal antibody activity was detected. The proportion of B cells in pleural fluid was greater than that in the circulation, and dietary therapy did not alter this difference. Pulmonary physiology improved during the initial 9-month period of diet therapy, but then the rate of fluid accumulation increased, causing respiratory compromise. Stability was achieved by a right-sided pleurodesis, followed 18 months later by a left pleurodesis with the addition of a shunt to provide internal lymph drainage.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lester</LastName><ForeName>L A</ForeName><Initials>LA</Initials></Author><Author ValidYN="Y"><LastName>Rothberg</LastName><ForeName>R M</ForeName><Initials>RM</Initials></Author><Author ValidYN="Y"><LastName>Krantman</LastName><ForeName>H J</ForeName><Initials>HJ</Initials></Author><Author ValidYN="Y"><LastName>Shermeta</LastName><ForeName>D W</ForeName><Initials>DW</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Allergy Clin Immunol</MedlineTA><NlmUniqueID>1275002</NlmUniqueID><ISSNLinking>0091-6749</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000907">Antibodies, Bacterial</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D007136">Immunoglobulins</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000907" MajorTopicYN="N">Antibodies, Bacterial</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007111" MajorTopicYN="N">Immunity, Cellular</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007136" MajorTopicYN="N">Immunoglobulins</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008168" MajorTopicYN="N">Lung</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008201" MajorTopicYN="N">Lymphangiectasis, Intestinal</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008214" MajorTopicYN="N">Lymphocytes</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010996" MajorTopicYN="N">Pleural Effusion</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011504" MajorTopicYN="N">Protein-Losing Enteropathies</DescriptorName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012397" MajorTopicYN="N">Rosette Formation</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1986</Year><Month>11</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1986</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1986</Year><Month>11</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">3782656</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Krantman, H J" sort="Krantman, H J" uniqKey="Krantman H" first="H J" last="Krantman">H J Krantman</name><name sortKey="Lester, L A" sort="Lester, L A" uniqKey="Lester L" first="L A" last="Lester">L A Lester</name><name sortKey="Rothberg, R M" sort="Rothberg, R M" uniqKey="Rothberg R" first="R M" last="Rothberg">R M Rothberg</name><name sortKey="Shermeta, D W" sort="Shermeta, D W" uniqKey="Shermeta D" first="D W" last="Shermeta">D W Shermeta</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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