Defective concanavalin A-induced suppression in bancroftian filariasis.
Identifieur interne : 005B66 ( PubMed/Checkpoint ); précédent : 005B65; suivant : 005B67Defective concanavalin A-induced suppression in bancroftian filariasis.
Auteurs : C R Vanamala ; P R NarayananSource :
- International archives of allergy and applied immunology [ 0020-5915 ] ; 1987.
Descripteurs français
- KwdFr :
- Activation des lymphocytes (), Cellules cultivées, Concanavaline A (pharmacologie), Coopération des lymphocytes, Facteurs suppresseurs immunologiques (biosynthèse), Filariose lymphatique (immunologie), Humains, Lymphocytes (), Lymphocytes (immunologie), Lymphocytes T régulateurs (), Lymphocytes T régulateurs (immunologie), Lymphoedème (immunologie), Relation dose-effet des médicaments, Tolérance immunitaire (), Wuchereria bancrofti (immunologie).
- MESH :
- biosynthèse : Facteurs suppresseurs immunologiques.
- immunologie : Filariose lymphatique, Lymphocytes, Lymphocytes T régulateurs, Lymphoedème, Wuchereria bancrofti.
- pharmacologie : Concanavaline A.
- Activation des lymphocytes, Cellules cultivées, Coopération des lymphocytes, Humains, Lymphocytes, Lymphocytes T régulateurs, Relation dose-effet des médicaments, Tolérance immunitaire.
English descriptors
- KwdEn :
- Cells, Cultured, Concanavalin A (pharmacology), Dose-Response Relationship, Drug, Elephantiasis, Filarial (immunology), Humans, Immune Tolerance (drug effects), Lymphedema (immunology), Lymphocyte Activation (drug effects), Lymphocyte Cooperation, Lymphocytes (drug effects), Lymphocytes (immunology), Suppressor Factors, Immunologic (biosynthesis), T-Lymphocytes, Regulatory (drug effects), T-Lymphocytes, Regulatory (immunology), Wuchereria bancrofti (immunology).
- MESH :
- chemical , biosynthesis : Suppressor Factors, Immunologic.
- chemical , pharmacology : Concanavalin A.
- drug effects : Immune Tolerance, Lymphocyte Activation, Lymphocytes, T-Lymphocytes, Regulatory.
- immunology : Elephantiasis, Filarial, Lymphedema, Lymphocytes, T-Lymphocytes, Regulatory, Wuchereria bancrofti.
- Cells, Cultured, Dose-Response Relationship, Drug, Humans, Lymphocyte Cooperation.
Abstract
A concanavalin-A-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. Both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. The reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients.
PubMed: 2956197
Affiliations:
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pubmed:2956197Le document en format XML
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Both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. The reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2956197</PMID><DateCreated><Year>1987</Year><Month>09</Month><Day>15</Day></DateCreated><DateCompleted><Year>1987</Year><Month>09</Month><Day>15</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0020-5915</ISSN><JournalIssue CitedMedium="Print"><Volume>83</Volume><Issue>4</Issue><PubDate><Year>1987</Year></PubDate></JournalIssue><Title>International archives of allergy and applied immunology</Title><ISOAbbreviation>Int. Arch. Allergy Appl. Immunol.</ISOAbbreviation></Journal><ArticleTitle>Defective concanavalin A-induced suppression in bancroftian filariasis.</ArticleTitle><Pagination><MedlinePgn>410-3</MedlinePgn></Pagination><Abstract><AbstractText>A concanavalin-A-induced suppressor cell assay was carried out in 10 patients with chronic filarial disease, 13 asymptomatic microfilaria carriers and 7 healthy subjects. Both the chronic filarial patients and the asymptomatic microfilaria carriers showed statistically significant reduced suppression indices when compared with the control subjects. The reduction in suppression indices was greater in the microfilaria carriers than in the chronic filarial patients.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vanamala</LastName><ForeName>C R</ForeName><Initials>CR</Initials></Author><Author ValidYN="Y"><LastName>Narayanan</LastName><ForeName>P R</ForeName><Initials>PR</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Int Arch Allergy Appl Immunol</MedlineTA><NlmUniqueID>0404561</NlmUniqueID><ISSNLinking>0020-5915</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D013491">Suppressor Factors, Immunologic</NameOfSubstance></Chemical><Chemical><RegistryNumber>11028-71-0</RegistryNumber><NameOfSubstance UI="D003208">Concanavalin A</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D002478" MajorTopicYN="N">Cells, Cultured</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003208" MajorTopicYN="N">Concanavalin A</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="Y">pharmacology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004305" MajorTopicYN="N">Dose-Response Relationship, Drug</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007108" MajorTopicYN="N">Immune Tolerance</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008213" MajorTopicYN="N">Lymphocyte Activation</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008211" MajorTopicYN="N">Lymphocyte Cooperation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008214" MajorTopicYN="N">Lymphocytes</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013491" MajorTopicYN="N">Suppressor Factors, Immunologic</DescriptorName><QualifierName UI="Q000096" MajorTopicYN="N">biosynthesis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D050378" MajorTopicYN="N">T-Lymphocytes, Regulatory</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1987</Year><Month>1</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1987</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1987</Year><Month>1</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2956197</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list></list><tree><noCountry><name sortKey="Narayanan, P R" sort="Narayanan, P R" uniqKey="Narayanan P" first="P R" last="Narayanan">P R Narayanan</name><name sortKey="Vanamala, C R" sort="Vanamala, C R" uniqKey="Vanamala C" first="C R" last="Vanamala">C R Vanamala</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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