LymphedemaV1, PubMed, Checkpoint, bibRecord, 005A87

The cat infected with Brugia pahangi as a model of human filariasis.

Identifieur interne : 005A87 ( PubMed/Checkpoint ); précédent : 005A86; suivant : 005A88

The cat infected with Brugia pahangi as a model of human filariasis.

Auteurs : D A Denham ; C. Fletcher

Source :

Ciba Foundation symposium [ 0300-5208 ] ; 1987.

RBID : pubmed:3595322

Descripteurs français

KwdFr :
- Animaux, Antigènes d'helminthe (immunologie), Antigènes de surface (immunologie), Brugia (immunologie), Brugia (physiologie), Chats (parasitologie), Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Humains, Lymphoedème (immunologie), Microfilaria (immunologie), Microfilaria (physiologie), Modèles animaux de maladie humaine, Production d'anticorps.
MESH :
- immunologie : Antigènes d'helminthe, Antigènes de surface, Brugia, Filariose lymphatique, Lymphoedème, Microfilaria.
- parasitologie : Chats, Filariose lymphatique.
- physiologie : Brugia, Microfilaria.
- Animaux, Humains, Modèles animaux de maladie humaine, Production d'anticorps.

English descriptors

KwdEn :
- Animals, Antibody Formation, Antigens, Helminth (immunology), Antigens, Surface (immunology), Brugia (immunology), Brugia (physiology), Cats (parasitology), Disease Models, Animal, Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Humans, Lymphedema (immunology), Microfilariae (immunology), Microfilariae (physiology).
MESH :
- chemical , immunology : Antigens, Helminth, Antigens, Surface.
- immunology : Brugia, Elephantiasis, Filarial, Lymphedema, Microfilariae.
- parasitology : Cats, Elephantiasis, Filarial.
- physiology : Brugia, Microfilariae.
- Animals, Antibody Formation, Disease Models, Animal, Humans.

Abstract

The responses of cats to Brugia pahangi, which parasitizes them in nature, mimic those of humans to Brugia malayi and Wuchereria bancrofti in many important respects. It is likely that many of the features of the relationship between host and parasite that can be studied in cats infected with B. pahangi also apply to humans, but for a variety of practical reasons cannot be demonstrated in humans. Both immunologically and parasitologically there is a profound difference between B. pahangi-infected cats that have microfilariae in their blood and those that either do not become microfilaraemic or clear their blood of microfilariae and become post-microfilaraemic. Microfilaraemic cats are susceptible to reinfection and fail to recognize the surface of the sheath of microfilariae. They also do not produce antibodies against several components recognized by post-microfilaraemic cats. Cats that have destroyed their microfilariae also destroy their adult worms and are very resistant to challenge with infective larvae. Apart from the unique ability to recognize the sheath of microfilariae in fluorescent antibody tests, sera from these cats react with microfilarial antigens at 61-81 kDa, antigens of infective larvae at 22 and 18.5 kDa and adult antigens at 34, 18, 16, 13 and 11.5 kDa. None of these antigens are recognized by microfilaraemic cats.

PubMed: 3595322

Affiliations:

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 006444
to stream PubMed, to step Curation: 006444

Links to Exploration step

pubmed:3595322

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The cat infected with Brugia pahangi as a model of human filariasis.</title>
<author><name sortKey="Denham, D A" sort="Denham, D A" uniqKey="Denham D" first="D A" last="Denham">D A Denham</name>
</author>
<author><name sortKey="Fletcher, C" sort="Fletcher, C" uniqKey="Fletcher C" first="C" last="Fletcher">C. Fletcher</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1987">1987</date>
<idno type="RBID">pubmed:3595322</idno>
<idno type="pmid">3595322</idno>
<idno type="wicri:Area/PubMed/Corpus">006444</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">006444</idno>
<idno type="wicri:Area/PubMed/Curation">006444</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">006444</idno>
<idno type="wicri:Area/PubMed/Checkpoint">006444</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">006444</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">The cat infected with Brugia pahangi as a model of human filariasis.</title>
<author><name sortKey="Denham, D A" sort="Denham, D A" uniqKey="Denham D" first="D A" last="Denham">D A Denham</name>
</author>
<author><name sortKey="Fletcher, C" sort="Fletcher, C" uniqKey="Fletcher C" first="C" last="Fletcher">C. Fletcher</name>
</author>
</analytic>
<series><title level="j">Ciba Foundation symposium</title>
<idno type="ISSN">0300-5208</idno>
<imprint><date when="1987" type="published">1987</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Antibody Formation</term>
<term>Antigens, Helminth (immunology)</term>
<term>Antigens, Surface (immunology)</term>
<term>Brugia (immunology)</term>
<term>Brugia (physiology)</term>
<term>Cats (parasitology)</term>
<term>Disease Models, Animal</term>
<term>Elephantiasis, Filarial (immunology)</term>
<term>Elephantiasis, Filarial (parasitology)</term>
<term>Humans</term>
<term>Lymphedema (immunology)</term>
<term>Microfilariae (immunology)</term>
<term>Microfilariae (physiology)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Antigènes d'helminthe (immunologie)</term>
<term>Antigènes de surface (immunologie)</term>
<term>Brugia (immunologie)</term>
<term>Brugia (physiologie)</term>
<term>Chats (parasitologie)</term>
<term>Filariose lymphatique (immunologie)</term>
<term>Filariose lymphatique (parasitologie)</term>
<term>Humains</term>
<term>Lymphoedème (immunologie)</term>
<term>Microfilaria (immunologie)</term>
<term>Microfilaria (physiologie)</term>
<term>Modèles animaux de maladie humaine</term>
<term>Production d'anticorps</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Antigens, Helminth</term>
<term>Antigens, Surface</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Antigènes d'helminthe</term>
<term>Antigènes de surface</term>
<term>Brugia</term>
<term>Filariose lymphatique</term>
<term>Lymphoedème</term>
<term>Microfilaria</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Brugia</term>
<term>Elephantiasis, Filarial</term>
<term>Lymphedema</term>
<term>Microfilariae</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Chats</term>
<term>Filariose lymphatique</term>
</keywords>
<keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Cats</term>
<term>Elephantiasis, Filarial</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Brugia</term>
<term>Microfilaria</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Brugia</term>
<term>Microfilariae</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Antibody Formation</term>
<term>Disease Models, Animal</term>
<term>Humans</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Humains</term>
<term>Modèles animaux de maladie humaine</term>
<term>Production d'anticorps</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The responses of cats to Brugia pahangi, which parasitizes them in nature, mimic those of humans to Brugia malayi and Wuchereria bancrofti in many important respects. It is likely that many of the features of the relationship between host and parasite that can be studied in cats infected with B. pahangi also apply to humans, but for a variety of practical reasons cannot be demonstrated in humans. Both immunologically and parasitologically there is a profound difference between B. pahangi-infected cats that have microfilariae in their blood and those that either do not become microfilaraemic or clear their blood of microfilariae and become post-microfilaraemic. Microfilaraemic cats are susceptible to reinfection and fail to recognize the surface of the sheath of microfilariae. They also do not produce antibodies against several components recognized by post-microfilaraemic cats. Cats that have destroyed their microfilariae also destroy their adult worms and are very resistant to challenge with infective larvae. Apart from the unique ability to recognize the sheath of microfilariae in fluorescent antibody tests, sera from these cats react with microfilarial antigens at 61-81 kDa, antigens of infective larvae at 22 and 18.5 kDa and adult antigens at 34, 18, 16, 13 and 11.5 kDa. None of these antigens are recognized by microfilaraemic cats.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">3595322</PMID>
<DateCreated><Year>1987</Year>
<Month>08</Month>
<Day>17</Day>
</DateCreated>
<DateCompleted><Year>1987</Year>
<Month>08</Month>
<Day>17</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>23</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0300-5208</ISSN>
<JournalIssue CitedMedium="Print"><Volume>127</Volume>
<PubDate><Year>1987</Year>
</PubDate>
</JournalIssue>
<Title>Ciba Foundation symposium</Title>
<ISOAbbreviation>Ciba Found. Symp.</ISOAbbreviation>
</Journal>
<ArticleTitle>The cat infected with Brugia pahangi as a model of human filariasis.</ArticleTitle>
<Pagination><MedlinePgn>225-35</MedlinePgn>
</Pagination>
<Abstract><AbstractText>The responses of cats to Brugia pahangi, which parasitizes them in nature, mimic those of humans to Brugia malayi and Wuchereria bancrofti in many important respects. It is likely that many of the features of the relationship between host and parasite that can be studied in cats infected with B. pahangi also apply to humans, but for a variety of practical reasons cannot be demonstrated in humans. Both immunologically and parasitologically there is a profound difference between B. pahangi-infected cats that have microfilariae in their blood and those that either do not become microfilaraemic or clear their blood of microfilariae and become post-microfilaraemic. Microfilaraemic cats are susceptible to reinfection and fail to recognize the surface of the sheath of microfilariae. They also do not produce antibodies against several components recognized by post-microfilaraemic cats. Cats that have destroyed their microfilariae also destroy their adult worms and are very resistant to challenge with infective larvae. Apart from the unique ability to recognize the sheath of microfilariae in fluorescent antibody tests, sera from these cats react with microfilarial antigens at 61-81 kDa, antigens of infective larvae at 22 and 18.5 kDa and adult antigens at 34, 18, 16, 13 and 11.5 kDa. None of these antigens are recognized by microfilaraemic cats.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Denham</LastName>
<ForeName>D A</ForeName>
<Initials>DA</Initials>
</Author>
<Author ValidYN="Y"><LastName>Fletcher</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Netherlands</Country>
<MedlineTA>Ciba Found Symp</MedlineTA>
<NlmUniqueID>0356636</NlmUniqueID>
<ISSNLinking>0300-5208</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000947">Antigens, Helminth</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000954">Antigens, Surface</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000917" MajorTopicYN="N">Antibody Formation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000947" MajorTopicYN="N">Antigens, Helminth</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000954" MajorTopicYN="N">Antigens, Surface</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002009" MajorTopicYN="N">Brugia</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D002415" MajorTopicYN="N">Cats</DescriptorName>
<QualifierName UI="Q000469" MajorTopicYN="Y">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004195" MajorTopicYN="Y">Disease Models, Animal</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
<QualifierName UI="Q000469" MajorTopicYN="N">parasitology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008842" MajorTopicYN="N">Microfilariae</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1987</Year>
<Month>1</Month>
<Day>1</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1987</Year>
<Month>1</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1987</Year>
<Month>1</Month>
<Day>1</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">3595322</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list></list>
<tree><noCountry><name sortKey="Denham, D A" sort="Denham, D A" uniqKey="Denham D" first="D A" last="Denham">D A Denham</name>
<name sortKey="Fletcher, C" sort="Fletcher, C" uniqKey="Fletcher C" first="C" last="Fletcher">C. Fletcher</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005A87 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 005A87 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:3595322
   |texte=   The cat infected with Brugia pahangi as a model of human filariasis.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:3595322" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024

	Serveur d'exploration sur le lymphœdème
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur le lymphœdème

The cat infected with Brugia pahangi as a model of human filariasis.

The cat infected with Brugia pahangi as a model of human filariasis.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki