Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.
Identifieur interne : 005611 ( PubMed/Checkpoint ); précédent : 005610; suivant : 005612Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.
Auteurs : G J Schuurkamp [Papouasie-Nouvelle-Guinée] ; R K Kereu ; P K BulungolSource :
- Papua and New Guinea medical journal [ 0031-1480 ] ; 1990.
Descripteurs français
- KwdFr :
- Adulte, Animaux, Contrôle des maladies contagieuses, Diéthylcarbamazine (pharmacologie), Diéthylcarbamazine (usage thérapeutique), Femelle, Filariose lymphatique (), Filariose lymphatique (traitement médicamenteux), Filariose lymphatique (épidémiologie), Humains, Incidence, Mâle, Nouvelle-Guinée, Paludisme (), Paludisme (épidémiologie), Prévalence, Vecteurs insectes (), Wuchereria bancrofti.
- MESH :
- pharmacologie : Diéthylcarbamazine.
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Diéthylcarbamazine.
- épidémiologie : Filariose lymphatique, Paludisme.
- Adulte, Animaux, Contrôle des maladies contagieuses, Femelle, Filariose lymphatique, Humains, Incidence, Mâle, Nouvelle-Guinée, Paludisme, Prévalence, Vecteurs insectes, Wuchereria bancrofti.
English descriptors
- KwdEn :
- Adult, Animals, Communicable Disease Control, Diethylcarbamazine (pharmacology), Diethylcarbamazine (therapeutic use), Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (prevention & control), Female, Humans, Incidence, Insect Vectors (drug effects), Malaria (epidemiology), Malaria (prevention & control), Male, New Guinea, Prevalence, Wuchereria bancrofti.
- MESH :
- chemical , pharmacology : Diethylcarbamazine.
- chemical , therapeutic use : Diethylcarbamazine.
- geographic : New Guinea.
- drug effects : Insect Vectors.
- drug therapy : Elephantiasis, Filarial.
- epidemiology : Elephantiasis, Filarial, Malaria.
- prevention & control : Elephantiasis, Filarial, Malaria.
- Adult, Animals, Communicable Disease Control, Female, Humans, Incidence, Male, Prevalence, Wuchereria bancrofti.
Abstract
The effects of a well-spaced diethylcarbamazine (DEC) mass drug application in areas highly endemic for Wuchereria bancrofti in Papua New Guinea are not known. In 1986 a semi-annual single-dose 6 mg/kg body weight administration of DEC was initiated in the Ok Tedi area of Western Province, Papua New Guinea. The rate of bancroftian filariasis in the area was 39%. Within two years the rate of detectable microfilaraemia was reduced from 31% to 11% in the treated group. The mean blood density of the parasite was reduced from 79 to 19 microfilariae per 20 microliters. A survey of untreated villages in the immediate area (not surveyed before 1988) showed a filariasis rate of 39%. A 14-fold difference in the total microfilaraemia count was noted between the two groups when 1988 data were compared. A reduction in the annual rate of filariasis may be monitored through a well-established passive case detection program for malaria. The DEC treatment program was well accepted despite side-effects encountered in 20% of the treated population early on in the program. The success of the 2-year Phase 1 program has expanded into an annual single-dose administration of DEC over a larger area.
PubMed: 2238834
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:2238834Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.</title><author><name sortKey="Schuurkamp, G J" sort="Schuurkamp, G J" uniqKey="Schuurkamp G" first="G J" last="Schuurkamp">G J Schuurkamp</name><affiliation wicri:level="1"><nlm:affiliation>Ok Tedi Mining Limited, Tabubil, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Ok Tedi Mining Limited, Tabubil</wicri:regionArea><wicri:noRegion>Tabubil</wicri:noRegion></affiliation></author><author><name sortKey="Kereu, R K" sort="Kereu, R K" uniqKey="Kereu R" first="R K" last="Kereu">R K Kereu</name></author><author><name sortKey="Bulungol, P K" sort="Bulungol, P K" uniqKey="Bulungol P" first="P K" last="Bulungol">P K Bulungol</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1990">1990</date><idno type="RBID">pubmed:2238834</idno><idno type="pmid">2238834</idno><idno type="wicri:Area/PubMed/Corpus">005D53</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">005D53</idno><idno type="wicri:Area/PubMed/Curation">005D53</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">005D53</idno><idno type="wicri:Area/PubMed/Checkpoint">005D53</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">005D53</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.</title><author><name sortKey="Schuurkamp, G J" sort="Schuurkamp, G J" uniqKey="Schuurkamp G" first="G J" last="Schuurkamp">G J Schuurkamp</name><affiliation wicri:level="1"><nlm:affiliation>Ok Tedi Mining Limited, Tabubil, Papua New Guinea.</nlm:affiliation><country xml:lang="fr">Papouasie-Nouvelle-Guinée</country><wicri:regionArea>Ok Tedi Mining Limited, Tabubil</wicri:regionArea><wicri:noRegion>Tabubil</wicri:noRegion></affiliation></author><author><name sortKey="Kereu, R K" sort="Kereu, R K" uniqKey="Kereu R" first="R K" last="Kereu">R K Kereu</name></author><author><name sortKey="Bulungol, P K" sort="Bulungol, P K" uniqKey="Bulungol P" first="P K" last="Bulungol">P K Bulungol</name></author></analytic><series><title level="j">Papua and New Guinea medical journal</title><idno type="ISSN">0031-1480</idno><imprint><date when="1990" type="published">1990</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Animals</term><term>Communicable Disease Control</term><term>Diethylcarbamazine (pharmacology)</term><term>Diethylcarbamazine (therapeutic use)</term><term>Elephantiasis, Filarial (drug therapy)</term><term>Elephantiasis, Filarial (epidemiology)</term><term>Elephantiasis, Filarial (prevention & control)</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Insect Vectors (drug effects)</term><term>Malaria (epidemiology)</term><term>Malaria (prevention & control)</term><term>Male</term><term>New Guinea</term><term>Prevalence</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Animaux</term><term>Contrôle des maladies contagieuses</term><term>Diéthylcarbamazine (pharmacologie)</term><term>Diéthylcarbamazine (usage thérapeutique)</term><term>Femelle</term><term>Filariose lymphatique ()</term><term>Filariose lymphatique (traitement médicamenteux)</term><term>Filariose lymphatique (épidémiologie)</term><term>Humains</term><term>Incidence</term><term>Mâle</term><term>Nouvelle-Guinée</term><term>Paludisme ()</term><term>Paludisme (épidémiologie)</term><term>Prévalence</term><term>Vecteurs insectes ()</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Diethylcarbamazine</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Diethylcarbamazine</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>New Guinea</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Insect Vectors</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Malaria</term></keywords><keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Diéthylcarbamazine</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Malaria</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Diéthylcarbamazine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Paludisme</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Animals</term><term>Communicable Disease Control</term><term>Female</term><term>Humans</term><term>Incidence</term><term>Male</term><term>Prevalence</term><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Animaux</term><term>Contrôle des maladies contagieuses</term><term>Femelle</term><term>Filariose lymphatique</term><term>Humains</term><term>Incidence</term><term>Mâle</term><term>Nouvelle-Guinée</term><term>Paludisme</term><term>Prévalence</term><term>Vecteurs insectes</term><term>Wuchereria bancrofti</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The effects of a well-spaced diethylcarbamazine (DEC) mass drug application in areas highly endemic for Wuchereria bancrofti in Papua New Guinea are not known. In 1986 a semi-annual single-dose 6 mg/kg body weight administration of DEC was initiated in the Ok Tedi area of Western Province, Papua New Guinea. The rate of bancroftian filariasis in the area was 39%. Within two years the rate of detectable microfilaraemia was reduced from 31% to 11% in the treated group. The mean blood density of the parasite was reduced from 79 to 19 microfilariae per 20 microliters. A survey of untreated villages in the immediate area (not surveyed before 1988) showed a filariasis rate of 39%. A 14-fold difference in the total microfilaraemia count was noted between the two groups when 1988 data were compared. A reduction in the annual rate of filariasis may be monitored through a well-established passive case detection program for malaria. The DEC treatment program was well accepted despite side-effects encountered in 20% of the treated population early on in the program. The success of the 2-year Phase 1 program has expanded into an annual single-dose administration of DEC over a larger area.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">2238834</PMID><DateCreated><Year>1990</Year><Month>12</Month><Day>07</Day></DateCreated><DateCompleted><Year>1990</Year><Month>12</Month><Day>07</Day></DateCompleted><DateRevised><Year>2013</Year><Month>11</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0031-1480</ISSN><JournalIssue CitedMedium="Print"><Volume>33</Volume><Issue>2</Issue><PubDate><Year>1990</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Papua and New Guinea medical journal</Title><ISOAbbreviation>P N G Med J</ISOAbbreviation></Journal><ArticleTitle>Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.</ArticleTitle><Pagination><MedlinePgn>89-98</MedlinePgn></Pagination><Abstract><AbstractText>The effects of a well-spaced diethylcarbamazine (DEC) mass drug application in areas highly endemic for Wuchereria bancrofti in Papua New Guinea are not known. In 1986 a semi-annual single-dose 6 mg/kg body weight administration of DEC was initiated in the Ok Tedi area of Western Province, Papua New Guinea. The rate of bancroftian filariasis in the area was 39%. Within two years the rate of detectable microfilaraemia was reduced from 31% to 11% in the treated group. The mean blood density of the parasite was reduced from 79 to 19 microfilariae per 20 microliters. A survey of untreated villages in the immediate area (not surveyed before 1988) showed a filariasis rate of 39%. A 14-fold difference in the total microfilaraemia count was noted between the two groups when 1988 data were compared. A reduction in the annual rate of filariasis may be monitored through a well-established passive case detection program for malaria. The DEC treatment program was well accepted despite side-effects encountered in 20% of the treated population early on in the program. The success of the 2-year Phase 1 program has expanded into an annual single-dose administration of DEC over a larger area.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Schuurkamp</LastName><ForeName>G J</ForeName><Initials>GJ</Initials><AffiliationInfo><Affiliation>Ok Tedi Mining Limited, Tabubil, Papua New Guinea.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kereu</LastName><ForeName>R K</ForeName><Initials>RK</Initials></Author><Author ValidYN="Y"><LastName>Bulungol</LastName><ForeName>P K</ForeName><Initials>PK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Papua New Guinea</Country><MedlineTA>P N G Med J</MedlineTA><NlmUniqueID>0376417</NlmUniqueID><ISSNLinking>0031-1480</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>V867Q8X3ZD</RegistryNumber><NameOfSubstance UI="D004049">Diethylcarbamazine</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003140" MajorTopicYN="N">Communicable Disease Control</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004049" MajorTopicYN="N">Diethylcarbamazine</DescriptorName><QualifierName UI="Q000494" MajorTopicYN="N">pharmacology</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="Y">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007303" MajorTopicYN="N">Insect Vectors</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="N">drug effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008288" MajorTopicYN="N">Malaria</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000517" MajorTopicYN="N">prevention & control</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009512" MajorTopicYN="N" Type="Geographic">New Guinea</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="Y">Wuchereria bancrofti</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1990</Year><Month>6</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1990</Year><Month>6</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1990</Year><Month>6</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">2238834</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Papouasie-Nouvelle-Guinée</li></country></list><tree><noCountry><name sortKey="Bulungol, P K" sort="Bulungol, P K" uniqKey="Bulungol P" first="P K" last="Bulungol">P K Bulungol</name><name sortKey="Kereu, R K" sort="Kereu, R K" uniqKey="Kereu R" first="R K" last="Kereu">R K Kereu</name></noCountry><country name="Papouasie-Nouvelle-Guinée"><noRegion><name sortKey="Schuurkamp, G J" sort="Schuurkamp, G J" uniqKey="Schuurkamp G" first="G J" last="Schuurkamp">G J Schuurkamp</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005611 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 005611 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:2238834
|texte= Diethylcarbamazine in the control of bancroftian filariasis in the highly endemic Ok Tedi area of Papua New Guinea: phase 1.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:2238834" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |