Clinical filarial disease in two ethnic endemic communities of Orissa, India.
Identifieur interne : 005053 ( PubMed/Checkpoint ); précédent : 005052; suivant : 005054Clinical filarial disease in two ethnic endemic communities of Orissa, India.
Auteurs : S K Kar [Inde] ; J. Mania ; P K KarSource :
- The Journal of tropical medicine and hygiene [ 0022-5304 ] ; 1993.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Anticorps antihelminthe (sang), Antigènes d'helminthe (sang), Complexe antigène-anticorps (sang), Enfant, Enfant d'âge préscolaire, Femelle, Filariose lymphatique (ethnologie), Filariose lymphatique (épidémiologie), Groupes ethniques, Humains, Immunoglobuline G (sang), Inde (épidémiologie), Maladie aigüe, Maladie chronique, Mâle, Nourrisson, Population d'origine océanique, Population rurale, Populations d'origine continentale, Prévalence, Susceptibilité à une maladie (ethnologie), Wuchereria bancrofti (immunologie).
- MESH :
- ethnologie : Filariose lymphatique, Susceptibilité à une maladie.
- immunologie : Wuchereria bancrofti.
- sang : Anticorps antihelminthe, Antigènes d'helminthe, Complexe antigène-anticorps, Immunoglobuline G.
- épidémiologie : Filariose lymphatique, Inde.
- Adolescent, Adulte, Adulte d'âge moyen, Animaux, Enfant, Enfant d'âge préscolaire, Femelle, Groupes ethniques, Humains, Maladie aigüe, Maladie chronique, Mâle, Nourrisson, Population d'origine océanique, Population rurale, Populations d'origine continentale, Prévalence.
- Wicri :
- geographic : Inde.
English descriptors
- KwdEn :
- Acute Disease, Adolescent, Adult, Animals, Antibodies, Helminth (blood), Antigen-Antibody Complex (blood), Antigens, Helminth (blood), Child, Child, Preschool, Chronic Disease, Continental Population Groups, Disease Susceptibility (ethnology), Elephantiasis, Filarial (epidemiology), Elephantiasis, Filarial (ethnology), Ethnic Groups, Female, Humans, Immunoglobulin G (blood), India (epidemiology), Infant, Male, Middle Aged, Oceanic Ancestry Group, Prevalence, Rural Population, Wuchereria bancrofti (immunology).
- MESH :
- chemical , blood : Antibodies, Helminth, Antigen-Antibody Complex, Antigens, Helminth, Immunoglobulin G.
- geographic , epidemiology : India.
- epidemiology : Elephantiasis, Filarial.
- ethnology : Disease Susceptibility, Elephantiasis, Filarial.
- immunology : Wuchereria bancrofti.
- Acute Disease, Adolescent, Adult, Animals, Child, Child, Preschool, Chronic Disease, Continental Population Groups, Ethnic Groups, Female, Humans, Infant, Male, Middle Aged, Oceanic Ancestry Group, Prevalence, Rural Population.
Abstract
To evaluate the possible role of ethnicity in susceptibility to filarial infection, a comparative study of the prevalence of filarial infection was initiated in an endemic village inhabited by two ethnic populations of mainlanders and tribals. An age and sex matched sampled population of 591 mainlanders and 106 tribals was studied by detailed clinical and parasitological (60 mm3 blood) examinations. Sera collected from both population groups (26 each) matched for clinical stage of infection were analysed for humoral immune responses such as antifilarial IgG, circulating filarial antigen and immune complex level. The overall prevalences of clinical disease and infection in both mainlanders (34.18 and 14.4%) and tribals (25.47 and 17.9%) were comparable. However, both annual average adenolymphangitic attack rate (1.77 year-1) and the prevalence of chronic filarial disease (22.6%) amongst tribals were significantly lower. No true elephantiasis was observed in tribals. No significant difference was observed in their humoral immune response, although the antifilarial antibody of IgG class in all stages of filarial infection was lower in tribals than in mainlanders. The results did not reveal any difference in susceptibility to filarial infection in the ethnic groups. The paucity of progressive lesions observed in tribals possibly reflects a difference in the anatomy of lymphatics or genetic or immunoregulatory mechanisms, that needs further study.
PubMed: 8411307
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An age and sex matched sampled population of 591 mainlanders and 106 tribals was studied by detailed clinical and parasitological (60 mm3 blood) examinations. Sera collected from both population groups (26 each) matched for clinical stage of infection were analysed for humoral immune responses such as antifilarial IgG, circulating filarial antigen and immune complex level. The overall prevalences of clinical disease and infection in both mainlanders (34.18 and 14.4%) and tribals (25.47 and 17.9%) were comparable. However, both annual average adenolymphangitic attack rate (1.77 year-1) and the prevalence of chronic filarial disease (22.6%) amongst tribals were significantly lower. No true elephantiasis was observed in tribals. No significant difference was observed in their humoral immune response, although the antifilarial antibody of IgG class in all stages of filarial infection was lower in tribals than in mainlanders. The results did not reveal any difference in susceptibility to filarial infection in the ethnic groups. The paucity of progressive lesions observed in tribals possibly reflects a difference in the anatomy of lymphatics or genetic or immunoregulatory mechanisms, that needs further study.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">8411307</PMID><DateCreated><Year>1993</Year><Month>11</Month><Day>18</Day></DateCreated><DateCompleted><Year>1993</Year><Month>11</Month><Day>18</Day></DateCompleted><DateRevised><Year>2004</Year><Month>11</Month><Day>17</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0022-5304</ISSN><JournalIssue CitedMedium="Print"><Volume>96</Volume><Issue>5</Issue><PubDate><Year>1993</Year><Month>Oct</Month></PubDate></JournalIssue><Title>The Journal of tropical medicine and hygiene</Title><ISOAbbreviation>J Trop Med Hyg</ISOAbbreviation></Journal><ArticleTitle>Clinical filarial disease in two ethnic endemic communities of Orissa, India.</ArticleTitle><Pagination><MedlinePgn>311-6</MedlinePgn></Pagination><Abstract><AbstractText>To evaluate the possible role of ethnicity in susceptibility to filarial infection, a comparative study of the prevalence of filarial infection was initiated in an endemic village inhabited by two ethnic populations of mainlanders and tribals. An age and sex matched sampled population of 591 mainlanders and 106 tribals was studied by detailed clinical and parasitological (60 mm3 blood) examinations. Sera collected from both population groups (26 each) matched for clinical stage of infection were analysed for humoral immune responses such as antifilarial IgG, circulating filarial antigen and immune complex level. The overall prevalences of clinical disease and infection in both mainlanders (34.18 and 14.4%) and tribals (25.47 and 17.9%) were comparable. However, both annual average adenolymphangitic attack rate (1.77 year-1) and the prevalence of chronic filarial disease (22.6%) amongst tribals were significantly lower. No true elephantiasis was observed in tribals. No significant difference was observed in their humoral immune response, although the antifilarial antibody of IgG class in all stages of filarial infection was lower in tribals than in mainlanders. The results did not reveal any difference in susceptibility to filarial infection in the ethnic groups. The paucity of progressive lesions observed in tribals possibly reflects a difference in the anatomy of lymphatics or genetic or immunoregulatory mechanisms, that needs further study.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kar</LastName><ForeName>S K</ForeName><Initials>SK</Initials><AffiliationInfo><Affiliation>Clinical Division, Regional Medical Research Centre ICMR, Bhubaneswar, Orissa, India.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mania</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Kar</LastName><ForeName>P K</ForeName><Initials>PK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>J Trop Med 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Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D044469" MajorTopicYN="N">Continental Population Groups</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004198" MajorTopicYN="N">Disease Susceptibility</DescriptorName><QualifierName UI="Q000208" MajorTopicYN="N">ethnology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004605" MajorTopicYN="N">Elephantiasis, Filarial</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000208" MajorTopicYN="Y">ethnology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005006" MajorTopicYN="Y">Ethnic Groups</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007074" MajorTopicYN="N">Immunoglobulin G</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007194" MajorTopicYN="N" Type="Geographic">India</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007223" MajorTopicYN="N">Infant</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D044468" MajorTopicYN="N">Oceanic Ancestry Group</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012424" MajorTopicYN="N">Rural Population</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014958" MajorTopicYN="N">Wuchereria bancrofti</DescriptorName><QualifierName UI="Q000276" MajorTopicYN="Y">immunology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1993</Year><Month>10</Month><Day>1</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1993</Year><Month>10</Month><Day>1</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1993</Year><Month>10</Month><Day>1</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8411307</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Kar, P K" sort="Kar, P K" uniqKey="Kar P" first="P K" last="Kar">P K Kar</name><name sortKey="Mania, J" sort="Mania, J" uniqKey="Mania J" first="J" last="Mania">J. Mania</name></noCountry><country name="Inde"><noRegion><name sortKey="Kar, S K" sort="Kar, S K" uniqKey="Kar S" first="S K" last="Kar">S K Kar</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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