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Quantitative evaluation of intraarterial lymphocyte injection therapy for lymph edema using MR imaging.

Identifieur interne : 004E19 ( PubMed/Checkpoint ); précédent : 004E18; suivant : 004E20

Quantitative evaluation of intraarterial lymphocyte injection therapy for lymph edema using MR imaging.

Auteurs : M. Harada [Japon] ; Y. Amano ; K. Matsuzaki ; Y. Hayashi ; H. Nishitani ; M. Yoshizumi ; O. Yoshida ; I. Katoh

Source :

RBID : pubmed:8086242

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English descriptors

Abstract

Five patients with unilateral leg lymph edema had intraarterial injections of lymphocytes in the affected leg with consequent improvement in 3. To assess the degree of lymph edema, T2 and intensity ratio between the 2 legs in STIR images were used. Mean and SD of T2 values in the subcutaneous tissue were measured using a triple echo sequence and found larger on the edematous side than in the opposite extremity. The mean T2 shortening obtained after the lymphocyte therapy correlated well with the reduction of limb circumference. Mean T2 reflects the fluid content, and SD of T2 the fluid distribution in the subcutaneous tissue. The degree of lymph edema and the effect of therapy can be evaluated quantitatively by measuring the value of the T2 relaxation time.

PubMed: 8086242


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Le document en format XML

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<title xml:lang="en">Quantitative evaluation of intraarterial lymphocyte injection therapy for lymph edema using MR imaging.</title>
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<name sortKey="Nishitani, H" sort="Nishitani, H" uniqKey="Nishitani H" first="H" last="Nishitani">H. Nishitani</name>
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<name sortKey="Yoshizumi, M" sort="Yoshizumi, M" uniqKey="Yoshizumi M" first="M" last="Yoshizumi">M. Yoshizumi</name>
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<name sortKey="Yoshida, O" sort="Yoshida, O" uniqKey="Yoshida O" first="O" last="Yoshida">O. Yoshida</name>
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<term>Female</term>
<term>Humans</term>
<term>Injections, Intra-Arterial</term>
<term>Leg (pathology)</term>
<term>Leukapheresis</term>
<term>Lymphedema (pathology)</term>
<term>Lymphedema (therapy)</term>
<term>Lymphocytes (pathology)</term>
<term>Magnetic Resonance Imaging</term>
<term>Middle Aged</term>
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<term>Humains</term>
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<term>Jambe (anatomopathologie)</term>
<term>Leucaphérèse</term>
<term>Lymphocytes (anatomopathologie)</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Muscles (anatomopathologie)</term>
<term>Peau (anatomopathologie)</term>
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<term>Peau</term>
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<term>Leg</term>
<term>Lymphedema</term>
<term>Lymphocytes</term>
<term>Muscles</term>
<term>Skin</term>
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<term>Aged</term>
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<div type="abstract" xml:lang="en">Five patients with unilateral leg lymph edema had intraarterial injections of lymphocytes in the affected leg with consequent improvement in 3. To assess the degree of lymph edema, T2 and intensity ratio between the 2 legs in STIR images were used. Mean and SD of T2 values in the subcutaneous tissue were measured using a triple echo sequence and found larger on the edematous side than in the opposite extremity. The mean T2 shortening obtained after the lymphocyte therapy correlated well with the reduction of limb circumference. Mean T2 reflects the fluid content, and SD of T2 the fluid distribution in the subcutaneous tissue. The degree of lymph edema and the effect of therapy can be evaluated quantitatively by measuring the value of the T2 relaxation time.</div>
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<AbstractText>Five patients with unilateral leg lymph edema had intraarterial injections of lymphocytes in the affected leg with consequent improvement in 3. To assess the degree of lymph edema, T2 and intensity ratio between the 2 legs in STIR images were used. Mean and SD of T2 values in the subcutaneous tissue were measured using a triple echo sequence and found larger on the edematous side than in the opposite extremity. The mean T2 shortening obtained after the lymphocyte therapy correlated well with the reduction of limb circumference. Mean T2 reflects the fluid content, and SD of T2 the fluid distribution in the subcutaneous tissue. The degree of lymph edema and the effect of therapy can be evaluated quantitatively by measuring the value of the T2 relaxation time.</AbstractText>
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