Selenium in the treatment of radiation-associated secondary lymphedema.
Identifieur interne : 003C87 ( PubMed/Checkpoint ); précédent : 003C86; suivant : 003C88Selenium in the treatment of radiation-associated secondary lymphedema.
Auteurs : Oliver Micke [Allemagne] ; Frank Bruns ; Ralph Mücke ; Ulrich Sch Fer ; Michael Glatzel ; Alexander F. Devries ; Klaus Schönekaes ; Klaus Kisters ; Jens BüntzelSource :
- International journal of radiation oncology, biology, physics [ 0360-3016 ] ; 2003.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Association thérapeutique, Cisplatine (administration et posologie), Cisplatine (usage thérapeutique), Femelle, Fluorouracil (administration et posologie), Humains, Lymphadénectomie (effets indésirables), Lymphoedème (traitement médicamenteux), Lymphoedème (étiologie), Lésions radio-induites (traitement médicamenteux), Lésions radio-induites (étiologie), Mastectomie, Mastectomie partielle, Mesure de la douleur, Oedème laryngé (), Oedème laryngé (traitement médicamenteux), Oedème laryngé (étiologie), Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique), Radio-isotopes du cobalt (usage thérapeutique), Radiothérapie (effets indésirables), Radiothérapie adjuvante (effets indésirables), Radiothérapie de haute énergie (effets indésirables), Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Sélénite de sodium (usage thérapeutique), Trachéostomie, Tumeurs de l'hypopharynx (), Tumeurs de l'hypopharynx (radiothérapie), Tumeurs de l'hypopharynx (traitement médicamenteux), Tumeurs du sein (), Tumeurs du sein (radiothérapie), Évidement ganglionnaire cervical.
- MESH :
- administration et posologie : Cisplatine, Fluorouracil.
- effets indésirables : Lymphadénectomie, Radiothérapie, Radiothérapie adjuvante, Radiothérapie de haute énergie.
- radiothérapie : Tumeurs de l'hypopharynx, Tumeurs du sein.
- traitement médicamenteux : Lymphoedème, Lésions radio-induites, Oedème laryngé, Tumeurs de l'hypopharynx.
- usage thérapeutique : Cisplatine, Protocoles de polychimiothérapie antinéoplasique, Radio-isotopes du cobalt, Sélénite de sodium.
- étiologie : Lymphoedème, Lésions radio-induites, Oedème laryngé.
- Adulte, Adulte d'âge moyen, Association thérapeutique, Femelle, Humains, Mastectomie, Mastectomie partielle, Mesure de la douleur, Oedème laryngé, Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Trachéostomie, Tumeurs de l'hypopharynx, Tumeurs du sein, Évidement ganglionnaire cervical.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Breast Neoplasms (radiotherapy), Breast Neoplasms (surgery), Cisplatin (administration & dosage), Cisplatin (therapeutic use), Cobalt Radioisotopes (therapeutic use), Combined Modality Therapy, Female, Fluorouracil (administration & dosage), Humans, Hypopharyngeal Neoplasms (complications), Hypopharyngeal Neoplasms (drug therapy), Hypopharyngeal Neoplasms (radiotherapy), Hypopharyngeal Neoplasms (surgery), Laryngeal Edema (drug therapy), Laryngeal Edema (etiology), Laryngeal Edema (surgery), Lymph Node Excision (adverse effects), Lymphedema (drug therapy), Lymphedema (etiology), Mastectomy, Mastectomy, Segmental, Middle Aged, Neck Dissection, Pain Measurement, Radiation Injuries (drug therapy), Radiation Injuries (etiology), Radiotherapy (adverse effects), Radiotherapy, Adjuvant (adverse effects), Radiotherapy, High-Energy (adverse effects), Sodium Selenite (therapeutic use), Tracheostomy, Treatment Outcome.
- MESH :
- chemical , administration & dosage : Cisplatin, Fluorouracil.
- adverse effects : Lymph Node Excision, Radiotherapy, Radiotherapy, Adjuvant, Radiotherapy, High-Energy.
- complications : Hypopharyngeal Neoplasms.
- drug therapy : Hypopharyngeal Neoplasms, Laryngeal Edema, Lymphedema, Radiation Injuries.
- etiology : Laryngeal Edema, Lymphedema, Radiation Injuries.
- radiotherapy : Breast Neoplasms, Hypopharyngeal Neoplasms.
- surgery : Breast Neoplasms, Hypopharyngeal Neoplasms, Laryngeal Edema.
- therapeutic use : Antineoplastic Combined Chemotherapy Protocols, Cisplatin, Cobalt Radioisotopes, Sodium Selenite.
- Adult, Aged, Aged, 80 and over, Combined Modality Therapy, Female, Humans, Mastectomy, Mastectomy, Segmental, Middle Aged, Neck Dissection, Pain Measurement, Tracheostomy, Treatment Outcome.
Abstract
The aim of this explorative study was to evaluate the impact of selenium in the treatment of lymphedema after radiotherapy.
PubMed: 12694822
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:12694822Le document en format XML
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<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Antineoplastic Combined Chemotherapy Protocols (therapeutic use)</term>
<term>Breast Neoplasms (radiotherapy)</term>
<term>Breast Neoplasms (surgery)</term>
<term>Cisplatin (administration & dosage)</term>
<term>Cisplatin (therapeutic use)</term>
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<term>Lymph Node Excision (adverse effects)</term>
<term>Lymphedema (drug therapy)</term>
<term>Lymphedema (etiology)</term>
<term>Mastectomy</term>
<term>Mastectomy, Segmental</term>
<term>Middle Aged</term>
<term>Neck Dissection</term>
<term>Pain Measurement</term>
<term>Radiation Injuries (drug therapy)</term>
<term>Radiation Injuries (etiology)</term>
<term>Radiotherapy (adverse effects)</term>
<term>Radiotherapy, Adjuvant (adverse effects)</term>
<term>Radiotherapy, High-Energy (adverse effects)</term>
<term>Sodium Selenite (therapeutic use)</term>
<term>Tracheostomy</term>
<term>Treatment Outcome</term>
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<term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Cisplatine (administration et posologie)</term>
<term>Cisplatine (usage thérapeutique)</term>
<term>Femelle</term>
<term>Fluorouracil (administration et posologie)</term>
<term>Humains</term>
<term>Lymphadénectomie (effets indésirables)</term>
<term>Lymphoedème (traitement médicamenteux)</term>
<term>Lymphoedème (étiologie)</term>
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<term>Lésions radio-induites (étiologie)</term>
<term>Mastectomie</term>
<term>Mastectomie partielle</term>
<term>Mesure de la douleur</term>
<term>Oedème laryngé ()</term>
<term>Oedème laryngé (traitement médicamenteux)</term>
<term>Oedème laryngé (étiologie)</term>
<term>Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique)</term>
<term>Radio-isotopes du cobalt (usage thérapeutique)</term>
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<term>Radiothérapie de haute énergie (effets indésirables)</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Sélénite de sodium (usage thérapeutique)</term>
<term>Trachéostomie</term>
<term>Tumeurs de l'hypopharynx ()</term>
<term>Tumeurs de l'hypopharynx (radiothérapie)</term>
<term>Tumeurs de l'hypopharynx (traitement médicamenteux)</term>
<term>Tumeurs du sein ()</term>
<term>Tumeurs du sein (radiothérapie)</term>
<term>Évidement ganglionnaire cervical</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Cisplatin</term>
<term>Fluorouracil</term>
</keywords>
<keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Cisplatine</term>
<term>Fluorouracil</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Lymph Node Excision</term>
<term>Radiotherapy</term>
<term>Radiotherapy, Adjuvant</term>
<term>Radiotherapy, High-Energy</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Hypopharyngeal Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Hypopharyngeal Neoplasms</term>
<term>Laryngeal Edema</term>
<term>Lymphedema</term>
<term>Radiation Injuries</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Lymphadénectomie</term>
<term>Radiothérapie</term>
<term>Radiothérapie adjuvante</term>
<term>Radiothérapie de haute énergie</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Laryngeal Edema</term>
<term>Lymphedema</term>
<term>Radiation Injuries</term>
</keywords>
<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en"><term>Breast Neoplasms</term>
<term>Hypopharyngeal Neoplasms</term>
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<keywords scheme="MESH" qualifier="radiothérapie" xml:lang="fr"><term>Tumeurs de l'hypopharynx</term>
<term>Tumeurs du sein</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Breast Neoplasms</term>
<term>Hypopharyngeal Neoplasms</term>
<term>Laryngeal Edema</term>
</keywords>
<keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Combined Chemotherapy Protocols</term>
<term>Cisplatin</term>
<term>Cobalt Radioisotopes</term>
<term>Sodium Selenite</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphoedème</term>
<term>Lésions radio-induites</term>
<term>Oedème laryngé</term>
<term>Tumeurs de l'hypopharynx</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Cisplatine</term>
<term>Protocoles de polychimiothérapie antinéoplasique</term>
<term>Radio-isotopes du cobalt</term>
<term>Sélénite de sodium</term>
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<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term>
<term>Lésions radio-induites</term>
<term>Oedème laryngé</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Combined Modality Therapy</term>
<term>Female</term>
<term>Humans</term>
<term>Mastectomy</term>
<term>Mastectomy, Segmental</term>
<term>Middle Aged</term>
<term>Neck Dissection</term>
<term>Pain Measurement</term>
<term>Tracheostomy</term>
<term>Treatment Outcome</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Association thérapeutique</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mastectomie</term>
<term>Mastectomie partielle</term>
<term>Mesure de la douleur</term>
<term>Oedème laryngé</term>
<term>Résultat thérapeutique</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Trachéostomie</term>
<term>Tumeurs de l'hypopharynx</term>
<term>Tumeurs du sein</term>
<term>Évidement ganglionnaire cervical</term>
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<front><div type="abstract" xml:lang="en">The aim of this explorative study was to evaluate the impact of selenium in the treatment of lymphedema after radiotherapy.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">12694822</PMID>
<DateCreated><Year>2003</Year>
<Month>04</Month>
<Day>15</Day>
</DateCreated>
<DateCompleted><Year>2003</Year>
<Month>05</Month>
<Day>21</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0360-3016</ISSN>
<JournalIssue CitedMedium="Print"><Volume>56</Volume>
<Issue>1</Issue>
<PubDate><Year>2003</Year>
<Month>May</Month>
<Day>01</Day>
</PubDate>
</JournalIssue>
<Title>International journal of radiation oncology, biology, physics</Title>
<ISOAbbreviation>Int. J. Radiat. Oncol. Biol. Phys.</ISOAbbreviation>
</Journal>
<ArticleTitle>Selenium in the treatment of radiation-associated secondary lymphedema.</ArticleTitle>
<Pagination><MedlinePgn>40-9</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">The aim of this explorative study was to evaluate the impact of selenium in the treatment of lymphedema after radiotherapy.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Between June 1996 and June 2001, 12 patients with edema of the arm and 36 patients with edema of the head-and-neck region were treated with selenium for therapy-related lymphedema. Of these 36 patients, 20 had interstitial endolaryngeal edema associated with stridor and dyspnea. All patients received sodium selenite over 4 to 6 weeks.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Self-assessment using a visual analog scale (n = 48) showed a reduction of 4.3 points when comparing pre- and posttreatment values (p < 0.05). Of 20 patients with endolaryngeal edema, 13 underwent no tracheostomy, 5 underwent a temporary tracheostomy, and only 2 underwent a permanent tracheostomy. Ten of 12 patients with arm edema showed a circumference reduction of the edematous limb and improvement in the Skin-Fold Index by 23.3 points. An improvement of one stage or more was shown by the Földi or the Miller score (n = 28) in 22 (Földi score) and in 24 (Miller score) patients.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Treatment with sodium selenite is well tolerated and easy to deliver. Additionally, our results suggest that sodium selenite has a positive effect on secondary-developing lymphedema caused by radiation therapy alone or by irradiation after surgery.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Micke</LastName>
<ForeName>Oliver</ForeName>
<Initials>O</Initials>
<AffiliationInfo><Affiliation>Department of Radiotherapy, Münster University Hospital, Münster, Germany. omicke@trace-elements.de</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bruns</LastName>
<ForeName>Frank</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Mücke</LastName>
<ForeName>Ralph</ForeName>
<Initials>R</Initials>
</Author>
<Author ValidYN="Y"><LastName>Schäfer</LastName>
<ForeName>Ulrich</ForeName>
<Initials>U</Initials>
</Author>
<Author ValidYN="Y"><LastName>Glatzel</LastName>
<ForeName>Michael</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>DeVries</LastName>
<ForeName>Alexander F</ForeName>
<Initials>AF</Initials>
</Author>
<Author ValidYN="Y"><LastName>Schönekaes</LastName>
<ForeName>Klaus</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Kisters</LastName>
<ForeName>Klaus</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Büntzel</LastName>
<ForeName>Jens</ForeName>
<Initials>J</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
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<MedlineJournalInfo><Country>United States</Country>
<MedlineTA>Int J Radiat Oncol Biol Phys</MedlineTA>
<NlmUniqueID>7603616</NlmUniqueID>
<ISSNLinking>0360-3016</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D003037">Cobalt Radioisotopes</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>HIW548RQ3W</RegistryNumber>
<NameOfSubstance UI="D018038">Sodium Selenite</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>Q20Q21Q62J</RegistryNumber>
<NameOfSubstance UI="D002945">Cisplatin</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>U3P01618RT</RegistryNumber>
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</MeshHeading>
<MeshHeading><DescriptorName UI="D000971" MajorTopicYN="N">Antineoplastic Combined Chemotherapy Protocols</DescriptorName>
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</MeshHeading>
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<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007819" MajorTopicYN="N">Laryngeal Edema</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008408" MajorTopicYN="N">Mastectomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015412" MajorTopicYN="N">Mastectomy, Segmental</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D037981" MajorTopicYN="N">Neck Dissection</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010147" MajorTopicYN="N">Pain Measurement</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011832" MajorTopicYN="N">Radiation Injuries</DescriptorName>
<QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName>
<QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011878" MajorTopicYN="N">Radiotherapy</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018714" MajorTopicYN="N">Radiotherapy, Adjuvant</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011882" MajorTopicYN="N">Radiotherapy, High-Energy</DescriptorName>
<QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018038" MajorTopicYN="N">Sodium Selenite</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D014139" MajorTopicYN="N">Tracheostomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year>
<Month>4</Month>
<Day>16</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2003</Year>
<Month>5</Month>
<Day>22</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2003</Year>
<Month>4</Month>
<Day>16</Day>
<Hour>5</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">12694822</ArticleId>
<ArticleId IdType="pii">S0360301602043900</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>Allemagne</li>
</country>
<region><li>District de Münster</li>
<li>Rhénanie-du-Nord-Westphalie</li>
</region>
<settlement><li>Münster</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Bruns, Frank" sort="Bruns, Frank" uniqKey="Bruns F" first="Frank" last="Bruns">Frank Bruns</name>
<name sortKey="Buntzel, Jens" sort="Buntzel, Jens" uniqKey="Buntzel J" first="Jens" last="Büntzel">Jens Büntzel</name>
<name sortKey="Devries, Alexander F" sort="Devries, Alexander F" uniqKey="Devries A" first="Alexander F" last="Devries">Alexander F. Devries</name>
<name sortKey="Glatzel, Michael" sort="Glatzel, Michael" uniqKey="Glatzel M" first="Michael" last="Glatzel">Michael Glatzel</name>
<name sortKey="Kisters, Klaus" sort="Kisters, Klaus" uniqKey="Kisters K" first="Klaus" last="Kisters">Klaus Kisters</name>
<name sortKey="Mucke, Ralph" sort="Mucke, Ralph" uniqKey="Mucke R" first="Ralph" last="Mücke">Ralph Mücke</name>
<name sortKey="Sch Fer, Ulrich" sort="Sch Fer, Ulrich" uniqKey="Sch Fer U" first="Ulrich" last="Sch Fer">Ulrich Sch Fer</name>
<name sortKey="Schonekaes, Klaus" sort="Schonekaes, Klaus" uniqKey="Schonekaes K" first="Klaus" last="Schönekaes">Klaus Schönekaes</name>
</noCountry>
<country name="Allemagne"><region name="Rhénanie-du-Nord-Westphalie"><name sortKey="Micke, Oliver" sort="Micke, Oliver" uniqKey="Micke O" first="Oliver" last="Micke">Oliver Micke</name>
</region>
</country>
</tree>
</affiliations>
</record>
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