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Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial.

Identifieur interne : 003C54 ( PubMed/Checkpoint ); précédent : 003C53; suivant : 003C55

Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial.

Auteurs : Colin J. Carati [Australie] ; Sandy N. Anderson ; Bren J. Gannon ; Neil B. Piller

Source :

RBID : pubmed:12973834

Descripteurs français

English descriptors

Abstract

The current study describes the results of a double blind, placebo-controlled, randomized, single crossover trial of the treatment of patients with postmastectomy lymphedema (PML) with low-level laser therapy (LLLT).

DOI: 10.1002/cncr.11641
PubMed: 12973834


Affiliations:


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pubmed:12973834

Le document en format XML

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<title xml:lang="en">Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial.</title>
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<name sortKey="Carati, Colin J" sort="Carati, Colin J" uniqKey="Carati C" first="Colin J" last="Carati">Colin J. Carati</name>
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<nlm:affiliation>Department of Anatomy, School of Medicine, Flinders University, Adelaide, South Australia, Australia. colin.carati@flinders.edu.au</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Department of Anatomy, School of Medicine, Flinders University, Adelaide, South Australia</wicri:regionArea>
<wicri:noRegion>South Australia</wicri:noRegion>
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<name sortKey="Anderson, Sandy N" sort="Anderson, Sandy N" uniqKey="Anderson S" first="Sandy N" last="Anderson">Sandy N. Anderson</name>
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<name sortKey="Gannon, Bren J" sort="Gannon, Bren J" uniqKey="Gannon B" first="Bren J" last="Gannon">Bren J. Gannon</name>
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<name sortKey="Piller, Neil B" sort="Piller, Neil B" uniqKey="Piller N" first="Neil B" last="Piller">Neil B. Piller</name>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Axilla</term>
<term>Breast Neoplasms (surgery)</term>
<term>Cross-Over Studies</term>
<term>Double-Blind Method</term>
<term>Extracellular Space</term>
<term>Female</term>
<term>Humans</term>
<term>Low-Level Light Therapy (methods)</term>
<term>Lymphedema (etiology)</term>
<term>Lymphedema (radiotherapy)</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Postoperative Complications</term>
<term>Tonometry, Ocular</term>
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<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Aisselle</term>
<term>Complications postopératoires</term>
<term>Espace extracellulaire</term>
<term>Femelle</term>
<term>Humains</term>
<term>Lymphoedème (radiothérapie)</term>
<term>Lymphoedème (étiologie)</term>
<term>Mastectomie</term>
<term>Méthode en double aveugle</term>
<term>Photothérapie de faible intensité ()</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tonométrie oculaire</term>
<term>Tumeurs du sein ()</term>
<term>Études croisées</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Low-Level Light Therapy</term>
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<keywords scheme="MESH" qualifier="radiotherapy" xml:lang="en">
<term>Lymphedema</term>
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<term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Breast Neoplasms</term>
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<term>Lymphoedème</term>
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<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Axilla</term>
<term>Cross-Over Studies</term>
<term>Double-Blind Method</term>
<term>Extracellular Space</term>
<term>Female</term>
<term>Humans</term>
<term>Mastectomy</term>
<term>Middle Aged</term>
<term>Postoperative Complications</term>
<term>Tonometry, Ocular</term>
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<term>Complications postopératoires</term>
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<term>Femelle</term>
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<term>Méthode en double aveugle</term>
<term>Photothérapie de faible intensité</term>
<term>Sujet âgé</term>
<term>Sujet âgé de 80 ans ou plus</term>
<term>Tonométrie oculaire</term>
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<term>Études croisées</term>
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<div type="abstract" xml:lang="en">The current study describes the results of a double blind, placebo-controlled, randomized, single crossover trial of the treatment of patients with postmastectomy lymphedema (PML) with low-level laser therapy (LLLT).</div>
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<Month>09</Month>
<Day>15</Day>
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<Month>09</Month>
<Day>30</Day>
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<Year>2015</Year>
<Month>11</Month>
<Day>19</Day>
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<Volume>98</Volume>
<Issue>6</Issue>
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<Year>2003</Year>
<Month>Sep</Month>
<Day>15</Day>
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<Title>Cancer</Title>
<ISOAbbreviation>Cancer</ISOAbbreviation>
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<ArticleTitle>Treatment of postmastectomy lymphedema with low-level laser therapy: a double blind, placebo-controlled trial.</ArticleTitle>
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<MedlinePgn>1114-22</MedlinePgn>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The current study describes the results of a double blind, placebo-controlled, randomized, single crossover trial of the treatment of patients with postmastectomy lymphedema (PML) with low-level laser therapy (LLLT).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Participants received placebo or one cycle or two cycles of LLLT to the axillary region of their affected arm. They were monitored for reductions in affected limb volume, upper body extracellular tissue fluid distribution, dermal tonometry, and range of limb movement.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">There was no significant improvement reported immediately after any of the treatments. However, the mean affected limb volume was found to be significantly reduced at 1 month or 3 months of follow-up after 2 cycles of active laser treatment. Approximately 31% of subjects had a clinically significant reduction in the volume of their PML-affected arm (> 200 mLs) approximately 2-3 months after 2 cycles of treatment. There was no significant effect of placebo treatment, or one cycle of laser treatment, on affected limb volume. The extracellular fluid index of the affected and unaffected arms and torso were reported to be significantly reduced at 3 months after 2 cycles of laser therapy, and there was significant softening of the tissues in the affected upper arm. Treatment did not appear to improve range of movement of the affected arm.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Two cycles of laser treatment were found to be effective in reducing the volume of the affected arm, extracellular fluid, and tissue hardness in approximately 33% of patients with postmastectomy lymphedema at 3 months after treatment.</AbstractText>
<CopyrightInformation>Copyright 2003 American Cancer Society.DOI 10.1002/cncr.11641</CopyrightInformation>
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<ForeName>Colin J</ForeName>
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