Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics.
Identifieur interne : 003947 ( PubMed/Checkpoint ); précédent : 003946; suivant : 003948Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics.
Auteurs : Roger E. Hofer [États-Unis] ; Juraj Sprung ; Michael G. Sarr ; Denise J. WedelSource :
- Canadian journal of anaesthesia = Journal canadien d'anesthesie [ 0832-610X ] ; 2005.
Descripteurs français
- KwdFr :
- Adulte, Analgésie autocontrôlée, Anastomose de Roux-en-Y, Anesthésie, Dexmédétomidine, Douleur postopératoire (traitement médicamenteux), Dérivation gastrique, Humains, Hypnotiques et sédatifs, Lymphoedème (), Mâle, Obésité morbide (), Position déclive, Stupéfiants, Surveillance peropératoire, Syndrome d'apnées obstructives du sommeil (), Ventilation artificielle.
- MESH :
- traitement médicamenteux : Douleur postopératoire.
- Adulte, Analgésie autocontrôlée, Anastomose de Roux-en-Y, Anesthésie, Dexmédétomidine, Dérivation gastrique, Humains, Hypnotiques et sédatifs, Lymphoedème, Mâle, Obésité morbide, Position déclive, Stupéfiants, Surveillance peropératoire, Syndrome d'apnées obstructives du sommeil, Ventilation artificielle.
English descriptors
- KwdEn :
- Adult, Analgesia, Patient-Controlled, Anastomosis, Roux-en-Y, Anesthesia, Dexmedetomidine, Gastric Bypass, Head-Down Tilt, Humans, Hypnotics and Sedatives, Lymphedema (complications), Male, Monitoring, Intraoperative, Narcotics, Obesity, Morbid (complications), Pain, Postoperative (drug therapy), Respiration, Artificial, Sleep Apnea, Obstructive (complications).
- MESH :
- chemical : Dexmedetomidine, Hypnotics and Sedatives, Narcotics.
- complications : Lymphedema, Obesity, Morbid, Sleep Apnea, Obstructive.
- drug therapy : Pain, Postoperative.
- Adult, Analgesia, Patient-Controlled, Anastomosis, Roux-en-Y, Anesthesia, Gastric Bypass, Head-Down Tilt, Humans, Male, Monitoring, Intraoperative, Respiration, Artificial.
Abstract
To describe the anesthetic management of a patient with extreme obesity undergoing bariatric surgery whose intraoperative narcotic management was entirely substituted with dexmedetomidine.
DOI: 10.1007/BF03027725
PubMed: 15684259
Affiliations:
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pubmed:15684259Le document en format XML
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<author><name sortKey="Hofer, Roger E" sort="Hofer, Roger E" uniqKey="Hofer R" first="Roger E" last="Hofer">Roger E. Hofer</name>
<affiliation wicri:level="2"><nlm:affiliation>Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street S.W., Rochester, MN 55905, USA.</nlm:affiliation>
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<wicri:regionArea>Department of Anesthesiology, Mayo Clinic College of Medicine, 200 First Street S.W., Rochester, MN 55905</wicri:regionArea>
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<author><name sortKey="Sprung, Juraj" sort="Sprung, Juraj" uniqKey="Sprung J" first="Juraj" last="Sprung">Juraj Sprung</name>
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<author><name sortKey="Sarr, Michael G" sort="Sarr, Michael G" uniqKey="Sarr M" first="Michael G" last="Sarr">Michael G. Sarr</name>
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<author><name sortKey="Wedel, Denise J" sort="Wedel, Denise J" uniqKey="Wedel D" first="Denise J" last="Wedel">Denise J. Wedel</name>
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<term>Anesthesia</term>
<term>Dexmedetomidine</term>
<term>Gastric Bypass</term>
<term>Head-Down Tilt</term>
<term>Humans</term>
<term>Hypnotics and Sedatives</term>
<term>Lymphedema (complications)</term>
<term>Male</term>
<term>Monitoring, Intraoperative</term>
<term>Narcotics</term>
<term>Obesity, Morbid (complications)</term>
<term>Pain, Postoperative (drug therapy)</term>
<term>Respiration, Artificial</term>
<term>Sleep Apnea, Obstructive (complications)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Analgésie autocontrôlée</term>
<term>Anastomose de Roux-en-Y</term>
<term>Anesthésie</term>
<term>Dexmédétomidine</term>
<term>Douleur postopératoire (traitement médicamenteux)</term>
<term>Dérivation gastrique</term>
<term>Humains</term>
<term>Hypnotiques et sédatifs</term>
<term>Lymphoedème ()</term>
<term>Mâle</term>
<term>Obésité morbide ()</term>
<term>Position déclive</term>
<term>Stupéfiants</term>
<term>Surveillance peropératoire</term>
<term>Syndrome d'apnées obstructives du sommeil ()</term>
<term>Ventilation artificielle</term>
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<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Dexmedetomidine</term>
<term>Hypnotics and Sedatives</term>
<term>Narcotics</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Lymphedema</term>
<term>Obesity, Morbid</term>
<term>Sleep Apnea, Obstructive</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Pain, Postoperative</term>
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<term>Analgesia, Patient-Controlled</term>
<term>Anastomosis, Roux-en-Y</term>
<term>Anesthesia</term>
<term>Gastric Bypass</term>
<term>Head-Down Tilt</term>
<term>Humans</term>
<term>Male</term>
<term>Monitoring, Intraoperative</term>
<term>Respiration, Artificial</term>
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<term>Analgésie autocontrôlée</term>
<term>Anastomose de Roux-en-Y</term>
<term>Anesthésie</term>
<term>Dexmédétomidine</term>
<term>Dérivation gastrique</term>
<term>Humains</term>
<term>Hypnotiques et sédatifs</term>
<term>Lymphoedème</term>
<term>Mâle</term>
<term>Obésité morbide</term>
<term>Position déclive</term>
<term>Stupéfiants</term>
<term>Surveillance peropératoire</term>
<term>Syndrome d'apnées obstructives du sommeil</term>
<term>Ventilation artificielle</term>
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<front><div type="abstract" xml:lang="en">To describe the anesthetic management of a patient with extreme obesity undergoing bariatric surgery whose intraoperative narcotic management was entirely substituted with dexmedetomidine.</div>
</front>
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<Month>06</Month>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<JournalIssue CitedMedium="Print"><Volume>52</Volume>
<Issue>2</Issue>
<PubDate><Year>2005</Year>
<Month>Feb</Month>
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<Title>Canadian journal of anaesthesia = Journal canadien d'anesthesie</Title>
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<ArticleTitle>Anesthesia for a patient with morbid obesity using dexmedetomidine without narcotics.</ArticleTitle>
<Pagination><MedlinePgn>176-80</MedlinePgn>
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<Abstract><AbstractText Label="PURPOSE" NlmCategory="OBJECTIVE">To describe the anesthetic management of a patient with extreme obesity undergoing bariatric surgery whose intraoperative narcotic management was entirely substituted with dexmedetomidine.</AbstractText>
<AbstractText Label="CLINICAL FEATURES" NlmCategory="METHODS">We describe a 433-kg morbidly obese patient with obstructive sleep apnea and pulmonary hypertension who underwent Roux-en-Y gastric bypass. Because of the concern that the use of narcotics might cause postoperative respiratory depression, we substituted their intraoperative use with a continuous infusion of dexmedetomidine (0.7 microg.kg(-1).hr(-1)). The anesthesia course was uneventful, and the intraoperative use of dexmedetomidine was associated with low anesthetic requirements (0.5 minimum alveolar concentration). After completion of the operation and after tracheal extubation, the dexmedetomidine infusion was continued uninterrupted throughout the end of the first postoperative day. The analgesic effects of dexmedetomidine extended narcotic-sparing effects into the postoperative period; the patient had lower narcotic requirements during the first postoperative day [48 mg of morphine by patient-controlled analgesia (PCA)] while still receiving dexmedetomidine, compared to the second postoperative day (morphine 148 mg by PCA) with similar pain scores.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Dexmedetomidine may be a useful anesthetic adjunct for patients who are susceptible to narcotic-induced respiratory depression. In this morbidly obese patient the narcotic-sparing effects of dexmedetomidine were evident both intraoperatively and postoperatively.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Hofer</LastName>
<ForeName>Roger E</ForeName>
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<Author ValidYN="Y"><LastName>Wedel</LastName>
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