[Surgical treatment of early-stage vulva carcinoma and the complications of the operation].
Identifieur interne : 003713 ( PubMed/Checkpoint ); précédent : 003712; suivant : 003714[Surgical treatment of early-stage vulva carcinoma and the complications of the operation].
Auteurs : J A De Hullu [Pays-Bas] ; A G J. Van Der ZeeSource :
- Nederlands tijdschrift voor geneeskunde [ 0028-2162 ] ; 2005.
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Abstract
The treatment of patients with early-stage squamous-cell carcinoma of the vulva (with a depth of invasion > 1 mm), i.e. stage T1 with a tumour diameter < or = 2 cm or T2 with a diameter > 2 cm without suspect groin nodes on palpation, has become less radical; in this way, the complications can be reduced without compromising the generally favourable prognosis. Wide local excision with tumour-free margins of 2 cm appears to be a safe option for the local treatment. Uni- or bilateral inguinofemoral lymphadenectomy with separate incisions is currently part of the standard treatment. The complications associated with this standard surgical treatment remain significant: there are frequent disorders of wound healing, wound infections, lymphoceles, lymphoedema and effects on psychosexual behaviour. The minimal invasive sentinel lymph-node procedure is a promising technique in patients with early-stage squamous-cell carcinoma of the vulva, but the safety of the procedure must still be proven.
PubMed: 15751805
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Van Der Zee</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2005">2005</date><idno type="RBID">pubmed:15751805</idno><idno type="pmid">15751805</idno><idno type="wicri:Area/PubMed/Corpus">003D48</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003D48</idno><idno type="wicri:Area/PubMed/Curation">003D48</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003D48</idno><idno type="wicri:Area/PubMed/Checkpoint">003D48</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003D48</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Surgical treatment of early-stage vulva carcinoma and the complications of the operation].</title><author><name sortKey="De Hullu, J A" sort="De Hullu, J A" uniqKey="De Hullu J" first="J A" last="De Hullu">J A De Hullu</name><affiliation wicri:level="1"><nlm:affiliation>Universitair Medisch Centrum St Radboud, afd. Gynaecologische Oncologie, huispost 415, Postbus 9101, 6500 HB Nijmegen. j.dehullu@obgyn.umcn.nl</nlm:affiliation><country wicri:rule="url">Pays-Bas</country></affiliation></author><author><name sortKey="Van Der Zee, A G J" sort="Van Der Zee, A G J" uniqKey="Van Der Zee A" first="A G J" last="Van Der Zee">A G J. Van Der Zee</name></author></analytic><series><title level="j">Nederlands tijdschrift voor geneeskunde</title><idno type="ISSN">0028-2162</idno><imprint><date when="2005" type="published">2005</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Carcinoma, Squamous Cell (surgery)</term><term>Female</term><term>Humans</term><term>Inguinal Canal</term><term>Lymph Node Excision</term><term>Neoplasm Staging</term><term>Postoperative Complications</term><term>Prognosis</term><term>Sentinel Lymph Node Biopsy</term><term>Surgical Procedures, Operative (adverse effects)</term><term>Vulvar Neoplasms (surgery)</term><term>Wound Healing</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Biopsie de noeud lymphatique sentinelle</term><term>Canal inguinal</term><term>Carcinome épidermoïde ()</term><term>Cicatrisation de plaie</term><term>Complications postopératoires</term><term>Femelle</term><term>Humains</term><term>Lymphadénectomie</term><term>Procédures de chirurgie opératoire (effets indésirables)</term><term>Pronostic</term><term>Stade de la tumeur</term><term>Tumeurs de la vulve ()</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Surgical Procedures, Operative</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Procédures de chirurgie opératoire</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Carcinoma, Squamous Cell</term><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Inguinal Canal</term><term>Lymph Node Excision</term><term>Neoplasm Staging</term><term>Postoperative Complications</term><term>Prognosis</term><term>Sentinel Lymph Node Biopsy</term><term>Wound Healing</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Biopsie de noeud lymphatique sentinelle</term><term>Canal inguinal</term><term>Carcinome épidermoïde</term><term>Cicatrisation de plaie</term><term>Complications postopératoires</term><term>Femelle</term><term>Humains</term><term>Lymphadénectomie</term><term>Pronostic</term><term>Stade de la tumeur</term><term>Tumeurs de la vulve</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The treatment of patients with early-stage squamous-cell carcinoma of the vulva (with a depth of invasion > 1 mm), i.e. stage T1 with a tumour diameter < or = 2 cm or T2 with a diameter > 2 cm without suspect groin nodes on palpation, has become less radical; in this way, the complications can be reduced without compromising the generally favourable prognosis. Wide local excision with tumour-free margins of 2 cm appears to be a safe option for the local treatment. Uni- or bilateral inguinofemoral lymphadenectomy with separate incisions is currently part of the standard treatment. The complications associated with this standard surgical treatment remain significant: there are frequent disorders of wound healing, wound infections, lymphoceles, lymphoedema and effects on psychosexual behaviour. The minimal invasive sentinel lymph-node procedure is a promising technique in patients with early-stage squamous-cell carcinoma of the vulva, but the safety of the procedure must still be proven.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15751805</PMID><DateCreated><Year>2005</Year><Month>03</Month><Day>08</Day></DateCreated><DateCompleted><Year>2005</Year><Month>03</Month><Day>31</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0028-2162</ISSN><JournalIssue CitedMedium="Print"><Volume>149</Volume><Issue>7</Issue><PubDate><Year>2005</Year><Month>Feb</Month><Day>12</Day></PubDate></JournalIssue><Title>Nederlands tijdschrift voor geneeskunde</Title><ISOAbbreviation>Ned Tijdschr Geneeskd</ISOAbbreviation></Journal><ArticleTitle>[Surgical treatment of early-stage vulva carcinoma and the complications of the operation].</ArticleTitle><Pagination><MedlinePgn>336-42</MedlinePgn></Pagination><Abstract><AbstractText>The treatment of patients with early-stage squamous-cell carcinoma of the vulva (with a depth of invasion > 1 mm), i.e. stage T1 with a tumour diameter < or = 2 cm or T2 with a diameter > 2 cm without suspect groin nodes on palpation, has become less radical; in this way, the complications can be reduced without compromising the generally favourable prognosis. Wide local excision with tumour-free margins of 2 cm appears to be a safe option for the local treatment. Uni- or bilateral inguinofemoral lymphadenectomy with separate incisions is currently part of the standard treatment. The complications associated with this standard surgical treatment remain significant: there are frequent disorders of wound healing, wound infections, lymphoceles, lymphoedema and effects on psychosexual behaviour. The minimal invasive sentinel lymph-node procedure is a promising technique in patients with early-stage squamous-cell carcinoma of the vulva, but the safety of the procedure must still be proven.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>de Hullu</LastName><ForeName>J A</ForeName><Initials>JA</Initials><AffiliationInfo><Affiliation>Universitair Medisch Centrum St Radboud, afd. Gynaecologische Oncologie, huispost 415, Postbus 9101, 6500 HB Nijmegen. j.dehullu@obgyn.umcn.nl</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van der Zee</LastName><ForeName>A G J</ForeName><Initials>AG</Initials></Author></AuthorList><Language>dut</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Chirurgische behandeling van vulvacarcinoom in een vroeg stadium en de complicaties van de ingreep.</VernacularTitle></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Ned Tijdschr Geneeskd</MedlineTA><NlmUniqueID>0400770</NlmUniqueID><ISSNLinking>0028-2162</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="CommentIn"><RefSource>Ned Tijdschr Geneeskd. 2005 May 14;149(20):1133; author reply 1133-4</RefSource><PMID Version="1">15932146</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D002294" MajorTopicYN="N">Carcinoma, Squamous Cell</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007264" MajorTopicYN="N">Inguinal Canal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008197" MajorTopicYN="N">Lymph Node Excision</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009367" MajorTopicYN="N">Neoplasm Staging</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011183" MajorTopicYN="Y">Postoperative Complications</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011379" MajorTopicYN="N">Prognosis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D021701" MajorTopicYN="N">Sentinel Lymph Node Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013514" MajorTopicYN="N">Surgical Procedures, Operative</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014846" MajorTopicYN="N">Vulvar Neoplasms</DescriptorName><QualifierName UI="Q000601" MajorTopicYN="Y">surgery</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014945" MajorTopicYN="N">Wound Healing</DescriptorName></MeshHeading></MeshHeadingList><NumberOfReferences>46</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2005</Year><Month>3</Month><Day>9</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2005</Year><Month>4</Month><Day>1</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2005</Year><Month>3</Month><Day>9</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15751805</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Pays-Bas</li></country></list><tree><noCountry><name sortKey="Van Der Zee, A G J" sort="Van Der Zee, A G J" uniqKey="Van Der Zee A" first="A G J" last="Van Der Zee">A G J. Van Der Zee</name></noCountry><country name="Pays-Bas"><noRegion><name sortKey="De Hullu, J A" sort="De Hullu, J A" uniqKey="De Hullu J" first="J A" last="De Hullu">J A De Hullu</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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