Filaria-induced monocyte dysfunction and its reversal following treatment.
Identifieur interne : 003629 ( PubMed/Checkpoint ); précédent : 003628; suivant : 003630Filaria-induced monocyte dysfunction and its reversal following treatment.
Auteurs : Roshanak Tolouei Semnani [États-Unis] ; Paul B. Keiser ; Yaya I. Coulibaly ; Falaye Keita ; Abdallah A. Diallo ; Diakaridia Traore ; Dapa A. Diallo ; Ogobara K. Doumbo ; Sekou F. Traore ; Joseph Kubofcik ; Amy D. Klion ; Thomas B. NutmanSource :
- Infection and immunity [ 0019-9567 ] ; 2006.
Descripteurs français
- KwdFr :
- Albendazole (usage thérapeutique), Animaux, Antihelminthiques (usage thérapeutique), Antiparasitaires (usage thérapeutique), Association de médicaments, Données de séquences moléculaires, Expression des gènes, Filariose lymphatique (immunologie), Filariose lymphatique (parasitologie), Filariose lymphatique (physiopathologie), Filariose lymphatique (traitement médicamenteux), Humains, Ivermectine (usage thérapeutique), Monocytes (anatomopathologie), Monocytes (métabolisme), Monocytes (parasitologie), Protéines du choc thermique (génétique), Protéines du choc thermique (métabolisme), Résultat thérapeutique, Wuchereria bancrofti (isolement et purification), Wuchereria bancrofti (pathogénicité).
- MESH :
- anatomopathologie : Monocytes.
- génétique : Protéines du choc thermique.
- immunologie : Filariose lymphatique.
- isolement et purification : Wuchereria bancrofti.
- métabolisme : Monocytes, Protéines du choc thermique.
- parasitologie : Filariose lymphatique, Monocytes.
- pathogénicité : Wuchereria bancrofti.
- physiopathologie : Filariose lymphatique.
- traitement médicamenteux : Filariose lymphatique.
- usage thérapeutique : Albendazole, Antihelminthiques, Antiparasitaires, Ivermectine.
- Animaux, Association de médicaments, Données de séquences moléculaires, Expression des gènes, Humains, Résultat thérapeutique.
English descriptors
- KwdEn :
- Albendazole (therapeutic use), Animals, Anthelmintics (therapeutic use), Antiparasitic Agents (therapeutic use), Drug Therapy, Combination, Elephantiasis, Filarial (drug therapy), Elephantiasis, Filarial (immunology), Elephantiasis, Filarial (parasitology), Elephantiasis, Filarial (physiopathology), Gene Expression, Heat-Shock Proteins (genetics), Heat-Shock Proteins (metabolism), Humans, Ivermectin (therapeutic use), Molecular Sequence Data, Monocytes (metabolism), Monocytes (parasitology), Monocytes (pathology), Treatment Outcome, Wuchereria bancrofti (isolation & purification), Wuchereria bancrofti (pathogenicity).
- MESH :
- chemical , genetics : Heat-Shock Proteins.
- chemical , metabolism : Heat-Shock Proteins.
- chemical , therapeutic use : Albendazole, Anthelmintics, Antiparasitic Agents, Ivermectin.
- drug therapy : Elephantiasis, Filarial.
- immunology : Elephantiasis, Filarial.
- isolation & purification : Wuchereria bancrofti.
- metabolism : Monocytes.
- parasitology : Elephantiasis, Filarial, Monocytes.
- pathogenicity : Wuchereria bancrofti.
- pathology : Monocytes.
- physiopathology : Elephantiasis, Filarial.
- Animals, Drug Therapy, Combination, Gene Expression, Humans, Molecular Sequence Data, Treatment Outcome.
Abstract
Monocyte dysfunction in filarial infection has been proposed as one mechanism underlying the diminished antigen-specific T-cell response seen in patent lymphatic filariasis. Cytokine/chemokine production and gene expression in monocytes from filaria-infected patients and uninfected healthy donors were assessed unstimulated and in response to stimulation with Staphylococcus aureus Cowan I bacteria plus gamma interferon both before and 8 months following treatment. Monocytes from filaria-infected individuals were studded with intracellular microfilarial antigens. Furthermore, monocytes from these individuals were less capable of producing interleukin-8 (IL-8), Exodus II, MIP-1alpha, MIP-1beta, and IL-1alpha and preferentially expressed genes involved in apoptosis and adhesion compared with monocytes from uninfected donors. Eight months following treatment with a single dose of ivermectin-albendazole, some of these defects were reversed, with monocyte production of IL-8, IL-1alpha, MIP-1alpha, and IL-10 being comparable to that seen in the uninfected controls. In addition, a marked increase in mRNA expression of genes associated with protein metabolism, particularly heat shock proteins, was seen compared with pretreatment expression. These data suggest that the function and gene expression of monocytes in filaria-infected patients are altered but that this dysfunction is partially reversible following antifilarial treatment.
DOI: 10.1128/IAI.01106-05
PubMed: 16861626
Affiliations:
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(pathology)</term><term>Treatment Outcome</term><term>Wuchereria bancrofti (isolation & purification)</term><term>Wuchereria bancrofti (pathogenicity)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Albendazole (usage thérapeutique)</term><term>Animaux</term><term>Antihelminthiques (usage thérapeutique)</term><term>Antiparasitaires (usage thérapeutique)</term><term>Association de médicaments</term><term>Données de séquences moléculaires</term><term>Expression des gènes</term><term>Filariose lymphatique (immunologie)</term><term>Filariose lymphatique (parasitologie)</term><term>Filariose lymphatique (physiopathologie)</term><term>Filariose lymphatique (traitement médicamenteux)</term><term>Humains</term><term>Ivermectine (usage thérapeutique)</term><term>Monocytes (anatomopathologie)</term><term>Monocytes (métabolisme)</term><term>Monocytes (parasitologie)</term><term>Protéines du choc thermique (génétique)</term><term>Protéines du choc thermique (métabolisme)</term><term>Résultat thérapeutique</term><term>Wuchereria bancrofti (isolement et purification)</term><term>Wuchereria bancrofti (pathogénicité)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Heat-Shock Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Heat-Shock Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Albendazole</term><term>Anthelmintics</term><term>Antiparasitic Agents</term><term>Ivermectin</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Monocytes</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Protéines du choc thermique</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Monocytes</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Monocytes</term><term>Protéines du choc thermique</term></keywords><keywords scheme="MESH" qualifier="parasitologie" xml:lang="fr"><term>Filariose lymphatique</term><term>Monocytes</term></keywords><keywords scheme="MESH" qualifier="parasitology" xml:lang="en"><term>Elephantiasis, Filarial</term><term>Monocytes</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Wuchereria bancrofti</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Monocytes</term></keywords><keywords scheme="MESH" qualifier="physiopathologie" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Elephantiasis, Filarial</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Filariose lymphatique</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Albendazole</term><term>Antihelminthiques</term><term>Antiparasitaires</term><term>Ivermectine</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Drug Therapy, Combination</term><term>Gene Expression</term><term>Humans</term><term>Molecular Sequence Data</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Association de médicaments</term><term>Données de séquences moléculaires</term><term>Expression des gènes</term><term>Humains</term><term>Résultat thérapeutique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Monocyte dysfunction in filarial infection has been proposed as one mechanism underlying the diminished antigen-specific T-cell response seen in patent lymphatic filariasis. Cytokine/chemokine production and gene expression in monocytes from filaria-infected patients and uninfected healthy donors were assessed unstimulated and in response to stimulation with Staphylococcus aureus Cowan I bacteria plus gamma interferon both before and 8 months following treatment. Monocytes from filaria-infected individuals were studded with intracellular microfilarial antigens. Furthermore, monocytes from these individuals were less capable of producing interleukin-8 (IL-8), Exodus II, MIP-1alpha, MIP-1beta, and IL-1alpha and preferentially expressed genes involved in apoptosis and adhesion compared with monocytes from uninfected donors. Eight months following treatment with a single dose of ivermectin-albendazole, some of these defects were reversed, with monocyte production of IL-8, IL-1alpha, MIP-1alpha, and IL-10 being comparable to that seen in the uninfected controls. In addition, a marked increase in mRNA expression of genes associated with protein metabolism, particularly heat shock proteins, was seen compared with pretreatment expression. These data suggest that the function and gene expression of monocytes in filaria-infected patients are altered but that this dysfunction is partially reversible following antifilarial treatment.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">16861626</PMID><DateCreated><Year>2006</Year><Month>07</Month><Day>24</Day></DateCreated><DateCompleted><Year>2006</Year><Month>08</Month><Day>29</Day></DateCompleted><DateRevised><Year>2016</Year><Month>10</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0019-9567</ISSN><JournalIssue CitedMedium="Print"><Volume>74</Volume><Issue>8</Issue><PubDate><Year>2006</Year><Month>Aug</Month></PubDate></JournalIssue><Title>Infection and immunity</Title><ISOAbbreviation>Infect. Immun.</ISOAbbreviation></Journal><ArticleTitle>Filaria-induced monocyte dysfunction and its reversal following treatment.</ArticleTitle><Pagination><MedlinePgn>4409-17</MedlinePgn></Pagination><Abstract><AbstractText>Monocyte dysfunction in filarial infection has been proposed as one mechanism underlying the diminished antigen-specific T-cell response seen in patent lymphatic filariasis. Cytokine/chemokine production and gene expression in monocytes from filaria-infected patients and uninfected healthy donors were assessed unstimulated and in response to stimulation with Staphylococcus aureus Cowan I bacteria plus gamma interferon both before and 8 months following treatment. Monocytes from filaria-infected individuals were studded with intracellular microfilarial antigens. Furthermore, monocytes from these individuals were less capable of producing interleukin-8 (IL-8), Exodus II, MIP-1alpha, MIP-1beta, and IL-1alpha and preferentially expressed genes involved in apoptosis and adhesion compared with monocytes from uninfected donors. Eight months following treatment with a single dose of ivermectin-albendazole, some of these defects were reversed, with monocyte production of IL-8, IL-1alpha, MIP-1alpha, and IL-10 being comparable to that seen in the uninfected controls. In addition, a marked increase in mRNA expression of genes associated with protein metabolism, particularly heat shock proteins, was seen compared with pretreatment expression. These data suggest that the function and gene expression of monocytes in filaria-infected patients are altered but that this dysfunction is partially reversible following antifilarial treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Semnani</LastName><ForeName>Roshanak Tolouei</ForeName><Initials>RT</Initials><AffiliationInfo><Affiliation>Helminth Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, 4 Center Drive, Room 4/126, National Institutes of Health, Bethesda, Maryland 20892, USA. rsemnani@niaid.nih.gov</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keiser</LastName><ForeName>Paul B</ForeName><Initials>PB</Initials></Author><Author ValidYN="Y"><LastName>Coulibaly</LastName><ForeName>Yaya I</ForeName><Initials>YI</Initials></Author><Author ValidYN="Y"><LastName>Keita</LastName><ForeName>Falaye</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Diallo</LastName><ForeName>Abdallah A</ForeName><Initials>AA</Initials></Author><Author ValidYN="Y"><LastName>Traore</LastName><ForeName>Diakaridia</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Diallo</LastName><ForeName>Dapa A</ForeName><Initials>DA</Initials></Author><Author ValidYN="Y"><LastName>Doumbo</LastName><ForeName>Ogobara K</ForeName><Initials>OK</Initials></Author><Author ValidYN="Y"><LastName>Traore</LastName><ForeName>Sekou F</ForeName><Initials>SF</Initials></Author><Author ValidYN="Y"><LastName>Kubofcik</LastName><ForeName>Joseph</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Klion</LastName><ForeName>Amy D</ForeName><Initials>AD</Initials></Author><Author ValidYN="Y"><LastName>Nutman</LastName><ForeName>Thomas B</ForeName><Initials>TB</Initials></Author></AuthorList><Language>eng</Language><DataBankList CompleteYN="Y"><DataBank><DataBankName>GEO</DataBankName><AccessionNumberList><AccessionNumber>GSE2135</AccessionNumber></AccessionNumberList></DataBank></DataBankList><GrantList CompleteYN="Y"><Grant><Agency>Intramural NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D052061">Research Support, N.I.H., Extramural</PublicationType><PublicationType UI="D052060">Research Support, N.I.H., Intramural</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Infect Immun</MedlineTA><NlmUniqueID>0246127</NlmUniqueID><ISSNLinking>0019-9567</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000871">Anthelmintics</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000977">Antiparasitic Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D006360">Heat-Shock Proteins</NameOfSubstance></Chemical><Chemical><RegistryNumber>70288-86-7</RegistryNumber><NameOfSubstance UI="D007559">Ivermectin</NameOfSubstance></Chemical><Chemical><RegistryNumber>F4216019LN</RegistryNumber><NameOfSubstance UI="D015766">Albendazole</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Exp Cell Res. 1996 Feb 25;223(1):163-70</RefSource><PMID Version="1">8635489</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Infect Dis. 1996 Mar;173(3):769-73</RefSource><PMID Version="1">8627051</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Exp Parasitol. 1996 Nov;84(2):282-90</RefSource><PMID Version="1">8932778</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 1997 Jun 15;158(12):5668-75</RefSource><PMID Version="1">9190915</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Immunity. 1998 Jun;8(6):657-65</RefSource><PMID Version="1">9655479</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Invest. 1999 Feb;103(4):571-7</RefSource><PMID Version="1">10021466</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2005 Jun;73(6):3385-93</RefSource><PMID Version="1">15908365</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 2001 Jul;23(7):389-99</RefSource><PMID Version="1">11472558</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 2001 Sep;69(9):5813-22</RefSource><PMID Version="1">11500459</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Immunology. 1999 May;97(1):107-16</RefSource><PMID Version="1">10447721</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2000 Jun 15;164(12):6453-60</RefSource><PMID Version="1">10843701</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Immunol. 2000 Sep;30(9):2669-78</RefSource><PMID Version="1">11009101</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5116-21</RefSource><PMID Version="1">11309499</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2001 Jun 1;166(11):6795-801</RefSource><PMID Version="1">11359838</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parasite Immunol. 2001 Jul;23(7):345-52</RefSource><PMID Version="1">11472554</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Jpn J Infect Dis. 2001 Jun;54(3):108-10</RefSource><PMID Version="1">11544400</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Eur J Immunol. 2002 Mar;32(3):858-67</RefSource><PMID Version="1">11870630</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genome Biol. 2002 Sep 13;3(10):RESEARCH0055</RefSource><PMID Version="1">12372143</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2002 Dec 1;169(11):6141-8</RefSource><PMID Version="1">12444117</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Med Microbiol Immunol. 2003 Feb;192(1):15-21</RefSource><PMID Version="1">12592559</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Genome Biol. 2003;4(5):P3</RefSource><PMID Version="1">12734009</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Blood. 2003 Jul 15;102(2):672-81</RefSource><PMID Version="1">12663451</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2003 Aug 15;171(4):1950-60</RefSource><PMID Version="1">12902498</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Rev Immunol. 2003 Sep;3(9):733-44</RefSource><PMID Version="1">12949497</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Am J Trop Med Hyg. 2003 Sep;69(3):331-5</RefSource><PMID Version="1">14628953</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Immunol. 2004 May 15;172(10):6229-38</RefSource><PMID Version="1">15128811</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mol Immunol. 2004 May;41(1):29-44</RefSource><PMID Version="1">15140573</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Scand J Clin Lab Invest Suppl. 1968;97:77-89</RefSource><PMID Version="1">4179068</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Clin Exp Immunol. 1993 Jan;91(1):58-62</RefSource><PMID Version="1">8419086</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Clin Invest. 1993 Oct;92(4):1667-73</RefSource><PMID Version="1">8408619</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Infect Immun. 1996 Nov;64(11):4706-13</RefSource><PMID Version="1">8890229</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D015766" MajorTopicYN="N">Albendazole</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000871" MajorTopicYN="N">Anthelmintics</DescriptorName><QualifierName UI="Q000627" MajorTopicYN="N">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000977" 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MajorTopicYN="N">isolation & purification</QualifierName><QualifierName UI="Q000472" MajorTopicYN="N">pathogenicity</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC1539612</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2006</Year><Month>7</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2006</Year><Month>8</Month><Day>30</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2006</Year><Month>7</Month><Day>25</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">16861626</ArticleId><ArticleId IdType="pii">74/8/4409</ArticleId><ArticleId IdType="doi">10.1128/IAI.01106-05</ArticleId><ArticleId IdType="pmc">PMC1539612</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country></list><tree><noCountry><name sortKey="Coulibaly, Yaya I" sort="Coulibaly, Yaya I" uniqKey="Coulibaly Y" first="Yaya I" last="Coulibaly">Yaya I. Coulibaly</name><name sortKey="Diallo, Abdallah A" sort="Diallo, Abdallah A" uniqKey="Diallo A" first="Abdallah A" last="Diallo">Abdallah A. Diallo</name><name sortKey="Diallo, Dapa A" sort="Diallo, Dapa A" uniqKey="Diallo D" first="Dapa A" last="Diallo">Dapa A. Diallo</name><name sortKey="Doumbo, Ogobara K" sort="Doumbo, Ogobara K" uniqKey="Doumbo O" first="Ogobara K" last="Doumbo">Ogobara K. Doumbo</name><name sortKey="Keiser, Paul B" sort="Keiser, Paul B" uniqKey="Keiser P" first="Paul B" last="Keiser">Paul B. Keiser</name><name sortKey="Keita, Falaye" sort="Keita, Falaye" uniqKey="Keita F" first="Falaye" last="Keita">Falaye Keita</name><name sortKey="Klion, Amy D" sort="Klion, Amy D" uniqKey="Klion A" first="Amy D" last="Klion">Amy D. Klion</name><name sortKey="Kubofcik, Joseph" sort="Kubofcik, Joseph" uniqKey="Kubofcik J" first="Joseph" last="Kubofcik">Joseph Kubofcik</name><name sortKey="Nutman, Thomas B" sort="Nutman, Thomas B" uniqKey="Nutman T" first="Thomas B" last="Nutman">Thomas B. Nutman</name><name sortKey="Traore, Diakaridia" sort="Traore, Diakaridia" uniqKey="Traore D" first="Diakaridia" last="Traore">Diakaridia Traore</name><name sortKey="Traore, Sekou F" sort="Traore, Sekou F" uniqKey="Traore S" first="Sekou F" last="Traore">Sekou F. Traore</name></noCountry><country name="États-Unis"><noRegion><name sortKey="Semnani, Roshanak Tolouei" sort="Semnani, Roshanak Tolouei" uniqKey="Semnani R" first="Roshanak Tolouei" last="Semnani">Roshanak Tolouei Semnani</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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