Tissue and urinary haemosiderin in chronic leg ulcers.
Identifieur interne : 003159 ( PubMed/Checkpoint ); précédent : 003158; suivant : 003160Tissue and urinary haemosiderin in chronic leg ulcers.
Auteurs : J. Tan [Royaume-Uni] ; A. Smith ; S. Abisi ; D. Eastham ; K G BurnandSource :
- European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery [ 1078-5884 ] ; 2007.
Descripteurs français
- KwdFr :
- Biopsie, Diagnostic différentiel, Drépanocytose (), Drépanocytose (diagnostic), Drépanocytose (métabolisme), Drépanocytose (urine), Humains, Hémosidérine (métabolisme), Hémosidérine (urine), Insuffisance veineuse (), Insuffisance veineuse (diagnostic), Insuffisance veineuse (métabolisme), Insuffisance veineuse (urine), Ischémie (), Ischémie (diagnostic), Ischémie (métabolisme), Ischémie (urine), Lymphoedème (), Lymphoedème (diagnostic), Lymphoedème (métabolisme), Lymphoedème (urine), Maladie chronique, Marqueurs biologiques (métabolisme), Marqueurs biologiques (urine), Peau (anatomopathologie), Peau (métabolisme), Polyarthrite rhumatoïde (), Polyarthrite rhumatoïde (diagnostic), Polyarthrite rhumatoïde (métabolisme), Polyarthrite rhumatoïde (urine), Reproductibilité des résultats, Ulcère de la jambe (anatomopathologie), Ulcère de la jambe (métabolisme), Ulcère de la jambe (urine), Ulcère de la jambe (étiologie), Valeur prédictive des tests.
- MESH :
- anatomopathologie : Peau, Ulcère de la jambe.
- diagnostic : Drépanocytose, Insuffisance veineuse, Ischémie, Lymphoedème, Polyarthrite rhumatoïde.
- métabolisme : Drépanocytose, Hémosidérine, Insuffisance veineuse, Ischémie, Lymphoedème, Marqueurs biologiques, Peau, Polyarthrite rhumatoïde, Ulcère de la jambe.
- étiologie : Drépanocytose, Hémosidérine, Insuffisance veineuse, Ischémie, Lymphoedème, Marqueurs biologiques, Polyarthrite rhumatoïde, Ulcère de la jambe.
- Biopsie, Diagnostic différentiel, Drépanocytose, Humains, Insuffisance veineuse, Ischémie, Lymphoedème, Maladie chronique, Polyarthrite rhumatoïde, Reproductibilité des résultats, Valeur prédictive des tests.
English descriptors
- KwdEn :
- Anemia, Sickle Cell (complications), Anemia, Sickle Cell (diagnosis), Anemia, Sickle Cell (metabolism), Anemia, Sickle Cell (urine), Arthritis, Rheumatoid (complications), Arthritis, Rheumatoid (diagnosis), Arthritis, Rheumatoid (metabolism), Arthritis, Rheumatoid (urine), Biomarkers (metabolism), Biomarkers (urine), Biopsy, Chronic Disease, Diagnosis, Differential, Hemosiderin (metabolism), Hemosiderin (urine), Humans, Ischemia (complications), Ischemia (diagnosis), Ischemia (metabolism), Ischemia (urine), Leg Ulcer (etiology), Leg Ulcer (metabolism), Leg Ulcer (pathology), Leg Ulcer (urine), Lymphedema (complications), Lymphedema (diagnosis), Lymphedema (metabolism), Lymphedema (urine), Predictive Value of Tests, Reproducibility of Results, Skin (metabolism), Skin (pathology), Venous Insufficiency (complications), Venous Insufficiency (diagnosis), Venous Insufficiency (metabolism), Venous Insufficiency (urine).
- MESH :
- chemical , metabolism : Biomarkers, Hemosiderin.
- complications : Anemia, Sickle Cell, Arthritis, Rheumatoid, Ischemia, Lymphedema, Venous Insufficiency.
- diagnosis : Anemia, Sickle Cell, Arthritis, Rheumatoid, Ischemia, Lymphedema, Venous Insufficiency.
- etiology : Leg Ulcer.
- metabolism : Anemia, Sickle Cell, Arthritis, Rheumatoid, Ischemia, Leg Ulcer, Lymphedema, Skin, Venous Insufficiency.
- pathology : Leg Ulcer, Skin.
- urine : Anemia, Sickle Cell, Arthritis, Rheumatoid, Biomarkers, Hemosiderin, Ischemia, Leg Ulcer, Lymphedema, Venous Insufficiency.
- Biopsy, Chronic Disease, Diagnosis, Differential, Humans, Predictive Value of Tests, Reproducibility of Results.
Abstract
The aim of this study was to assess the relationship between urinary and tissue haemosiderin in chronic leg ulcers, and its value as a diagnostic test for venous ulceration.
DOI: 10.1016/j.ejvs.2007.02.006
PubMed: 17601755
Affiliations:
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Tan</name><affiliation wicri:level="1"><nlm:affiliation>St. Thomas' Hospital, Academic Department of Surgery, Cardiovascular Division, 1st Floor, North Wing, Lambeth Palace Road, London SE1 7EH, UK. justin.tan@yahoo.co.uk</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>St. Thomas' Hospital, Academic Department of Surgery, Cardiovascular Division, 1st Floor, North Wing, Lambeth Palace Road, London SE1 7EH</wicri:regionArea><wicri:noRegion>London SE1 7EH</wicri:noRegion></affiliation></author><author><name sortKey="Smith, A" sort="Smith, A" uniqKey="Smith A" first="A" last="Smith">A. Smith</name></author><author><name sortKey="Abisi, S" sort="Abisi, S" uniqKey="Abisi S" first="S" last="Abisi">S. Abisi</name></author><author><name sortKey="Eastham, D" sort="Eastham, D" uniqKey="Eastham D" first="D" last="Eastham">D. 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Disease</term><term>Diagnosis, Differential</term><term>Hemosiderin (metabolism)</term><term>Hemosiderin (urine)</term><term>Humans</term><term>Ischemia (complications)</term><term>Ischemia (diagnosis)</term><term>Ischemia (metabolism)</term><term>Ischemia (urine)</term><term>Leg Ulcer (etiology)</term><term>Leg Ulcer (metabolism)</term><term>Leg Ulcer (pathology)</term><term>Leg Ulcer (urine)</term><term>Lymphedema (complications)</term><term>Lymphedema (diagnosis)</term><term>Lymphedema (metabolism)</term><term>Lymphedema (urine)</term><term>Predictive Value of Tests</term><term>Reproducibility of Results</term><term>Skin (metabolism)</term><term>Skin (pathology)</term><term>Venous Insufficiency (complications)</term><term>Venous Insufficiency (diagnosis)</term><term>Venous Insufficiency (metabolism)</term><term>Venous Insufficiency (urine)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Biopsie</term><term>Diagnostic différentiel</term><term>Drépanocytose 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(urine)</term><term>Reproductibilité des résultats</term><term>Ulcère de la jambe (anatomopathologie)</term><term>Ulcère de la jambe (métabolisme)</term><term>Ulcère de la jambe (urine)</term><term>Ulcère de la jambe (étiologie)</term><term>Valeur prédictive des tests</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Biomarkers</term><term>Hemosiderin</term></keywords><keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Peau</term><term>Ulcère de la jambe</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Anemia, Sickle Cell</term><term>Arthritis, Rheumatoid</term><term>Ischemia</term><term>Lymphedema</term><term>Venous Insufficiency</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Anemia, Sickle Cell</term><term>Arthritis, Rheumatoid</term><term>Ischemia</term><term>Lymphedema</term><term>Venous Insufficiency</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Drépanocytose</term><term>Insuffisance veineuse</term><term>Ischémie</term><term>Lymphoedème</term><term>Polyarthrite rhumatoïde</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Leg Ulcer</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Anemia, Sickle Cell</term><term>Arthritis, Rheumatoid</term><term>Ischemia</term><term>Leg Ulcer</term><term>Lymphedema</term><term>Skin</term><term>Venous Insufficiency</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Drépanocytose</term><term>Hémosidérine</term><term>Insuffisance veineuse</term><term>Ischémie</term><term>Lymphoedème</term><term>Marqueurs biologiques</term><term>Peau</term><term>Polyarthrite rhumatoïde</term><term>Ulcère de la jambe</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Leg Ulcer</term><term>Skin</term></keywords><keywords scheme="MESH" qualifier="urine" xml:lang="en"><term>Anemia, Sickle Cell</term><term>Arthritis, Rheumatoid</term><term>Biomarkers</term><term>Hemosiderin</term><term>Ischemia</term><term>Leg Ulcer</term><term>Lymphedema</term><term>Venous Insufficiency</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Drépanocytose</term><term>Hémosidérine</term><term>Insuffisance veineuse</term><term>Ischémie</term><term>Lymphoedème</term><term>Marqueurs biologiques</term><term>Polyarthrite rhumatoïde</term><term>Ulcère de la jambe</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biopsy</term><term>Chronic Disease</term><term>Diagnosis, Differential</term><term>Humans</term><term>Predictive Value of Tests</term><term>Reproducibility of Results</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Biopsie</term><term>Diagnostic différentiel</term><term>Drépanocytose</term><term>Humains</term><term>Insuffisance veineuse</term><term>Ischémie</term><term>Lymphoedème</term><term>Maladie chronique</term><term>Polyarthrite rhumatoïde</term><term>Reproductibilité des résultats</term><term>Valeur prédictive des tests</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of this study was to assess the relationship between urinary and tissue haemosiderin in chronic leg ulcers, and its value as a diagnostic test for venous ulceration.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">17601755</PMID><DateCreated><Year>2007</Year><Month>08</Month><Day>10</Day></DateCreated><DateCompleted><Year>2007</Year><Month>10</Month><Day>04</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">1078-5884</ISSN><JournalIssue CitedMedium="Print"><Volume>34</Volume><Issue>3</Issue><PubDate><Year>2007</Year><Month>Sep</Month></PubDate></JournalIssue><Title>European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery</Title><ISOAbbreviation>Eur J Vasc Endovasc Surg</ISOAbbreviation></Journal><ArticleTitle>Tissue and urinary haemosiderin in chronic leg ulcers.</ArticleTitle><Pagination><MedlinePgn>355-60</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">The aim of this study was to assess the relationship between urinary and tissue haemosiderin in chronic leg ulcers, and its value as a diagnostic test for venous ulceration.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">45 patients with chronic leg ulcers were recruited to the study (24 venous, 6 ischaemic, 6 lymphoedematous, 5 rheumatoid and 4 sickle cell). Punch biopsy of the ulcer edge was taken and early morning urine samples were collected. Positive Prussian-blue urinary haemosiderin granules were measured with a haemocytometer following Perls' staining. The percentage area of histological section staining positively with Perls' was measured using image analysis.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">84 urine samples and 46 ulcer biopsies were collected. Urinary haemosiderin was present in 92% of venous ulcer patients, but was absent in the ischaemic ulcer patients (p<0.0001). Significantly more urinary haemosiderin granules were detected in venous ulcer patients compared with patients who had lymphoedema (p<0.05). Tissue haemosiderin was detected in all ulcer types investigated. No correlation was found between the amounts of haemosiderin deposited in the tissue and the amount found in urine (r(2)=0.06).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Haemosiderin is present in the urine of most patients with venous ulcers but not in ischaemia ulcers.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Tan</LastName><ForeName>J</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>St. Thomas' Hospital, Academic Department of Surgery, Cardiovascular Division, 1st Floor, North Wing, Lambeth Palace Road, London SE1 7EH, UK. justin.tan@yahoo.co.uk</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Smith</LastName><ForeName>A</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Abisi</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Eastham</LastName><ForeName>D</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Burnand</LastName><ForeName>K G</ForeName><Initials>KG</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2007</Year><Month>07</Month><Day>02</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Eur J Vasc Endovasc Surg</MedlineTA><NlmUniqueID>9512728</NlmUniqueID><ISSNLinking>1078-5884</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>9011-92-1</RegistryNumber><NameOfSubstance UI="D006485">Hemosiderin</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000755" MajorTopicYN="N">Anemia, Sickle Cell</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001172" MajorTopicYN="N">Arthritis, Rheumatoid</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002908" MajorTopicYN="N">Chronic Disease</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006485" MajorTopicYN="N">Hemosiderin</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007511" MajorTopicYN="N">Ischemia</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007871" MajorTopicYN="N">Leg Ulcer</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015203" MajorTopicYN="N">Reproducibility of Results</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012867" MajorTopicYN="N">Skin</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014689" MajorTopicYN="N">Venous Insufficiency</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000652" MajorTopicYN="N">urine</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2006</Year><Month>07</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2007</Year><Month>02</Month><Day>13</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2007</Year><Month>7</Month><Day>3</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2007</Year><Month>10</Month><Day>5</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2007</Year><Month>7</Month><Day>3</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">17601755</ArticleId><ArticleId IdType="pii">S1078-5884(07)00134-7</ArticleId><ArticleId IdType="doi">10.1016/j.ejvs.2007.02.006</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Abisi, S" sort="Abisi, S" uniqKey="Abisi S" first="S" last="Abisi">S. Abisi</name><name sortKey="Burnand, K G" sort="Burnand, K G" uniqKey="Burnand K" first="K G" last="Burnand">K G Burnand</name><name sortKey="Eastham, D" sort="Eastham, D" uniqKey="Eastham D" first="D" last="Eastham">D. Eastham</name><name sortKey="Smith, A" sort="Smith, A" uniqKey="Smith A" first="A" last="Smith">A. Smith</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Tan, J" sort="Tan, J" uniqKey="Tan J" first="J" last="Tan">J. Tan</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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