Serveur d'exploration sur le lymphœdème

Attention, ce site est en cours de développement !
Attention, site généré par des moyens informatiques à partir de corpus bruts.
Les informations ne sont donc pas validées.

Angiosarcoma complicating systemic sclerosis: a case report.

Identifieur interne : 003086 ( PubMed/Checkpoint ); précédent : 003085; suivant : 003087

Angiosarcoma complicating systemic sclerosis: a case report.

Auteurs : Margaret A. Fonder [États-Unis] ; Deborah K. Douglas

Source :

RBID : pubmed:18666387

Descripteurs français

English descriptors

Abstract

Cutaneous angiosarcoma is a rare malignant vascular tumor with a poor prognosis, most commonly affecting elderly white men. Diagnosis usually is delayed because the tumor has a highly variable and often innocuous presentation. Cutaneous angiosarcoma has been associated with a number of conditions and factors, including chronic lymphedema, prior radiation therapy, exposure to chemicals, and vascular malformations. We report the case of a 40-year-old black man with systemic sclerosis (SSc) who developed a cutaneous angiosarcoma in an area of sclerodermatous scalp. We propose that vascular endothelial growth factor (VEGF) overexpression in sclerodermatous skin may predispose a patient to the development of vascular tumors, such as angiosarcoma. Because early diagnosis and treatment positively impact survival outcome in patients with angiosarcoma, it is essential that physicians recognize the association of angiosarcoma and SSc and maintain a low threshold for performing a biopsy when suspicious lesions are present on sclerodermatous skin.

PubMed: 18666387


Affiliations:


Links toward previous steps (curation, corpus...)


Links to Exploration step

pubmed:18666387

Le document en format XML

<record>
<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Angiosarcoma complicating systemic sclerosis: a case report.</title>
<author>
<name sortKey="Fonder, Margaret A" sort="Fonder, Margaret A" uniqKey="Fonder M" first="Margaret A" last="Fonder">Margaret A. Fonder</name>
<affiliation wicri:level="2">
<nlm:affiliation>Greater Baltimore Medical Center, Maryland, USA. margofonder@gmail.com</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Greater Baltimore Medical Center, Maryland</wicri:regionArea>
<placeName>
<region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Douglas, Deborah K" sort="Douglas, Deborah K" uniqKey="Douglas D" first="Deborah K" last="Douglas">Deborah K. Douglas</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2008">2008</date>
<idno type="RBID">pubmed:18666387</idno>
<idno type="pmid">18666387</idno>
<idno type="wicri:Area/PubMed/Corpus">003184</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003184</idno>
<idno type="wicri:Area/PubMed/Curation">003184</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003184</idno>
<idno type="wicri:Area/PubMed/Checkpoint">003184</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003184</idno>
</publicationStmt>
<sourceDesc>
<biblStruct>
<analytic>
<title xml:lang="en">Angiosarcoma complicating systemic sclerosis: a case report.</title>
<author>
<name sortKey="Fonder, Margaret A" sort="Fonder, Margaret A" uniqKey="Fonder M" first="Margaret A" last="Fonder">Margaret A. Fonder</name>
<affiliation wicri:level="2">
<nlm:affiliation>Greater Baltimore Medical Center, Maryland, USA. margofonder@gmail.com</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Greater Baltimore Medical Center, Maryland</wicri:regionArea>
<placeName>
<region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Douglas, Deborah K" sort="Douglas, Deborah K" uniqKey="Douglas D" first="Deborah K" last="Douglas">Deborah K. Douglas</name>
</author>
</analytic>
<series>
<title level="j">Cutis</title>
<idno type="ISSN">0011-4162</idno>
<imprint>
<date when="2008" type="published">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Head and Neck Neoplasms (etiology)</term>
<term>Head and Neck Neoplasms (pathology)</term>
<term>Head and Neck Neoplasms (surgery)</term>
<term>Hemangiosarcoma (etiology)</term>
<term>Hemangiosarcoma (pathology)</term>
<term>Hemangiosarcoma (surgery)</term>
<term>Humans</term>
<term>Male</term>
<term>Scalp</term>
<term>Scleroderma, Systemic (complications)</term>
<term>Scleroderma, Systemic (pathology)</term>
<term>Skin Neoplasms (etiology)</term>
<term>Skin Neoplasms (pathology)</term>
<term>Skin Neoplasms (surgery)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adulte</term>
<term>Cuir chevelu</term>
<term>Humains</term>
<term>Hémangiosarcome ()</term>
<term>Hémangiosarcome (anatomopathologie)</term>
<term>Hémangiosarcome (étiologie)</term>
<term>Mâle</term>
<term>Sclérodermie systémique ()</term>
<term>Sclérodermie systémique (anatomopathologie)</term>
<term>Tumeurs cutanées ()</term>
<term>Tumeurs cutanées (anatomopathologie)</term>
<term>Tumeurs cutanées (étiologie)</term>
<term>Tumeurs de la tête et du cou ()</term>
<term>Tumeurs de la tête et du cou (anatomopathologie)</term>
<term>Tumeurs de la tête et du cou (étiologie)</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr">
<term>Hémangiosarcome</term>
<term>Sclérodermie systémique</term>
<term>Tumeurs cutanées</term>
<term>Tumeurs de la tête et du cou</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en">
<term>Scleroderma, Systemic</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Head and Neck Neoplasms</term>
<term>Hemangiosarcoma</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en">
<term>Head and Neck Neoplasms</term>
<term>Hemangiosarcoma</term>
<term>Scleroderma, Systemic</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Head and Neck Neoplasms</term>
<term>Hemangiosarcoma</term>
<term>Skin Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="étiologie" xml:lang="fr">
<term>Hémangiosarcome</term>
<term>Tumeurs cutanées</term>
<term>Tumeurs de la tête et du cou</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Humans</term>
<term>Male</term>
<term>Scalp</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adulte</term>
<term>Cuir chevelu</term>
<term>Humains</term>
<term>Hémangiosarcome</term>
<term>Mâle</term>
<term>Sclérodermie systémique</term>
<term>Tumeurs cutanées</term>
<term>Tumeurs de la tête et du cou</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Cutaneous angiosarcoma is a rare malignant vascular tumor with a poor prognosis, most commonly affecting elderly white men. Diagnosis usually is delayed because the tumor has a highly variable and often innocuous presentation. Cutaneous angiosarcoma has been associated with a number of conditions and factors, including chronic lymphedema, prior radiation therapy, exposure to chemicals, and vascular malformations. We report the case of a 40-year-old black man with systemic sclerosis (SSc) who developed a cutaneous angiosarcoma in an area of sclerodermatous scalp. We propose that vascular endothelial growth factor (VEGF) overexpression in sclerodermatous skin may predispose a patient to the development of vascular tumors, such as angiosarcoma. Because early diagnosis and treatment positively impact survival outcome in patients with angiosarcoma, it is essential that physicians recognize the association of angiosarcoma and SSc and maintain a low threshold for performing a biopsy when suspicious lesions are present on sclerodermatous skin.</div>
</front>
</TEI>
<pubmed>
<MedlineCitation Status="MEDLINE" Owner="NLM">
<PMID Version="1">18666387</PMID>
<DateCreated>
<Year>2008</Year>
<Month>07</Month>
<Day>31</Day>
</DateCreated>
<DateCompleted>
<Year>2008</Year>
<Month>11</Month>
<Day>18</Day>
</DateCompleted>
<DateRevised>
<Year>2013</Year>
<Month>09</Month>
<Day>12</Day>
</DateRevised>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Print">0011-4162</ISSN>
<JournalIssue CitedMedium="Print">
<Volume>81</Volume>
<Issue>6</Issue>
<PubDate>
<Year>2008</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Cutis</Title>
<ISOAbbreviation>Cutis</ISOAbbreviation>
</Journal>
<ArticleTitle>Angiosarcoma complicating systemic sclerosis: a case report.</ArticleTitle>
<Pagination>
<MedlinePgn>468-72</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText>Cutaneous angiosarcoma is a rare malignant vascular tumor with a poor prognosis, most commonly affecting elderly white men. Diagnosis usually is delayed because the tumor has a highly variable and often innocuous presentation. Cutaneous angiosarcoma has been associated with a number of conditions and factors, including chronic lymphedema, prior radiation therapy, exposure to chemicals, and vascular malformations. We report the case of a 40-year-old black man with systemic sclerosis (SSc) who developed a cutaneous angiosarcoma in an area of sclerodermatous scalp. We propose that vascular endothelial growth factor (VEGF) overexpression in sclerodermatous skin may predispose a patient to the development of vascular tumors, such as angiosarcoma. Because early diagnosis and treatment positively impact survival outcome in patients with angiosarcoma, it is essential that physicians recognize the association of angiosarcoma and SSc and maintain a low threshold for performing a biopsy when suspicious lesions are present on sclerodermatous skin.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y">
<Author ValidYN="Y">
<LastName>Fonder</LastName>
<ForeName>Margaret A</ForeName>
<Initials>MA</Initials>
<AffiliationInfo>
<Affiliation>Greater Baltimore Medical Center, Maryland, USA. margofonder@gmail.com</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y">
<LastName>Douglas</LastName>
<ForeName>Deborah K</ForeName>
<Initials>DK</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList>
<PublicationType UI="D002363">Case Reports</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo>
<Country>United States</Country>
<MedlineTA>Cutis</MedlineTA>
<NlmUniqueID>0006440</NlmUniqueID>
<ISSNLinking>0011-4162</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList>
<MeshHeading>
<DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006258" MajorTopicYN="N">Head and Neck Neoplasms</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006394" MajorTopicYN="N">Hemangiosarcoma</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012535" MajorTopicYN="Y">Scalp</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012595" MajorTopicYN="N">Scleroderma, Systemic</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName UI="D012878" MajorTopicYN="N">Skin Neoplasms</DescriptorName>
<QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
<QualifierName UI="Q000601" MajorTopicYN="N">surgery</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData>
<History>
<PubMedPubDate PubStatus="pubmed">
<Year>2008</Year>
<Month>8</Month>
<Day>1</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline">
<Year>2008</Year>
<Month>11</Month>
<Day>19</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez">
<Year>2008</Year>
<Month>8</Month>
<Day>1</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList>
<ArticleId IdType="pubmed">18666387</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations>
<list>
<country>
<li>États-Unis</li>
</country>
<region>
<li>Maryland</li>
</region>
</list>
<tree>
<noCountry>
<name sortKey="Douglas, Deborah K" sort="Douglas, Deborah K" uniqKey="Douglas D" first="Deborah K" last="Douglas">Deborah K. Douglas</name>
</noCountry>
<country name="États-Unis">
<region name="Maryland">
<name sortKey="Fonder, Margaret A" sort="Fonder, Margaret A" uniqKey="Fonder M" first="Margaret A" last="Fonder">Margaret A. Fonder</name>
</region>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003086 | SxmlIndent | more

Ou

HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 003086 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    LymphedemaV1
   |flux=    PubMed
   |étape=   Checkpoint
   |type=    RBID
   |clé=     pubmed:18666387
   |texte=   Angiosarcoma complicating systemic sclerosis: a case report.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:18666387" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1 

Wicri

This area was generated with Dilib version V0.6.31.
Data generation: Sat Nov 4 17:40:35 2017. Site generation: Tue Feb 13 16:42:16 2024