Doxycycline sclerodesis as a treatment option for persistent Morel-Lavallée lesions.
Identifieur interne : 001B63 ( PubMed/Checkpoint ); précédent : 001B62; suivant : 001B64Doxycycline sclerodesis as a treatment option for persistent Morel-Lavallée lesions.
Auteurs : Abhishek Bansal [Inde] ; Naval Bhatia ; Archana Singh ; Ashwani Kumar SinghSource :
- Injury [ 1879-0267 ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Antibactériens (administration et posologie), Bandages de compression, Cicatrisation de plaie, Cytoponction, Doxycycline (administration et posologie), Débridement, Enfant, Facteurs temps, Femelle, Humains, Lymphoedème (), Lymphoedème (imagerie diagnostique), Lymphoedème (traitement médicamenteux), Mâle, Radiographie, Résultat thérapeutique, Sujet âgé, Traumatismes des tissus mous (), Traumatismes des tissus mous (imagerie diagnostique), Traumatismes des tissus mous (traitement médicamenteux), Études de suivi.
- MESH :
- administration et posologie : Antibactériens, Doxycycline.
- imagerie diagnostique : Lymphoedème, Traumatismes des tissus mous.
- traitement médicamenteux : Lymphoedème, Traumatismes des tissus mous.
- Adolescent, Adulte, Adulte d'âge moyen, Bandages de compression, Cicatrisation de plaie, Cytoponction, Débridement, Enfant, Facteurs temps, Femelle, Humains, Lymphoedème, Mâle, Radiographie, Résultat thérapeutique, Sujet âgé, Traumatismes des tissus mous, Études de suivi.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Anti-Bacterial Agents (administration & dosage), Biopsy, Fine-Needle, Child, Compression Bandages, Debridement, Doxycycline (administration & dosage), Female, Follow-Up Studies, Humans, Lymphedema (diagnostic imaging), Lymphedema (drug therapy), Lymphedema (therapy), Male, Middle Aged, Radiography, Soft Tissue Injuries (diagnostic imaging), Soft Tissue Injuries (drug therapy), Soft Tissue Injuries (therapy), Time Factors, Treatment Outcome, Wound Healing.
- MESH :
- chemical , administration & dosage : Anti-Bacterial Agents, Doxycycline.
- diagnostic imaging : Lymphedema, Soft Tissue Injuries.
- drug therapy : Lymphedema, Soft Tissue Injuries.
- therapy : Lymphedema, Soft Tissue Injuries.
- Adolescent, Adult, Aged, Biopsy, Fine-Needle, Child, Compression Bandages, Debridement, Female, Follow-Up Studies, Humans, Male, Middle Aged, Radiography, Time Factors, Treatment Outcome, Wound Healing.
Abstract
Morel-Lavallée lesion is a rare cause of subcutaneous swelling, caused by post-traumatic shearing of the hypodermis from the underlying fascia. Treatment of such lesions is still not well established.
DOI: 10.1016/j.injury.2011.11.024
PubMed: 22204771
Affiliations:
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uniqKey="Bansal A" first="Abhishek" last="Bansal">Abhishek Bansal</name><affiliation wicri:level="1"><nlm:affiliation>Sports Injury Centre, Safdarjang Hospital, New Delhi 110029, India. drabhishekbansal@ymail.com</nlm:affiliation><country xml:lang="fr">Inde</country><wicri:regionArea>Sports Injury Centre, Safdarjang Hospital, New Delhi 110029</wicri:regionArea><wicri:noRegion>New Delhi 110029</wicri:noRegion></affiliation></author><author><name sortKey="Bhatia, Naval" sort="Bhatia, Naval" uniqKey="Bhatia N" first="Naval" last="Bhatia">Naval Bhatia</name></author><author><name sortKey="Singh, Archana" sort="Singh, Archana" uniqKey="Singh A" first="Archana" last="Singh">Archana Singh</name></author><author><name sortKey="Singh, Ashwani Kumar" sort="Singh, Ashwani Kumar" uniqKey="Singh A" first="Ashwani Kumar" last="Singh">Ashwani Kumar Singh</name></author></analytic><series><title level="j">Injury</title><idno type="eISSN">1879-0267</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Anti-Bacterial Agents (administration & dosage)</term><term>Biopsy, Fine-Needle</term><term>Child</term><term>Compression Bandages</term><term>Debridement</term><term>Doxycycline (administration & dosage)</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Lymphedema (diagnostic imaging)</term><term>Lymphedema (drug therapy)</term><term>Lymphedema (therapy)</term><term>Male</term><term>Middle Aged</term><term>Radiography</term><term>Soft Tissue Injuries (diagnostic imaging)</term><term>Soft Tissue Injuries (drug therapy)</term><term>Soft Tissue Injuries (therapy)</term><term>Time Factors</term><term>Treatment Outcome</term><term>Wound Healing</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Antibactériens (administration et posologie)</term><term>Bandages de compression</term><term>Cicatrisation de plaie</term><term>Cytoponction</term><term>Doxycycline (administration et posologie)</term><term>Débridement</term><term>Enfant</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphoedème ()</term><term>Lymphoedème (imagerie diagnostique)</term><term>Lymphoedème (traitement médicamenteux)</term><term>Mâle</term><term>Radiographie</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Traumatismes des tissus mous ()</term><term>Traumatismes des tissus mous (imagerie diagnostique)</term><term>Traumatismes des tissus mous (traitement médicamenteux)</term><term>Études de suivi</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-Bacterial Agents</term><term>Doxycycline</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Antibactériens</term><term>Doxycycline</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Lymphedema</term><term>Soft Tissue Injuries</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Lymphedema</term><term>Soft Tissue Injuries</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Lymphoedème</term><term>Traumatismes des tissus mous</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term><term>Soft Tissue Injuries</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Lymphoedème</term><term>Traumatismes des tissus mous</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Biopsy, Fine-Needle</term><term>Child</term><term>Compression Bandages</term><term>Debridement</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Radiography</term><term>Time Factors</term><term>Treatment Outcome</term><term>Wound Healing</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Bandages de compression</term><term>Cicatrisation de plaie</term><term>Cytoponction</term><term>Débridement</term><term>Enfant</term><term>Facteurs temps</term><term>Femelle</term><term>Humains</term><term>Lymphoedème</term><term>Mâle</term><term>Radiographie</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Traumatismes des tissus mous</term><term>Études de suivi</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Morel-Lavallée lesion is a rare cause of subcutaneous swelling, caused by post-traumatic shearing of the hypodermis from the underlying fascia. Treatment of such lesions is still not well established.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">22204771</PMID><DateCreated><Year>2012</Year><Month>12</Month><Day>11</Day></DateCreated><DateCompleted><Year>2013</Year><Month>05</Month><Day>15</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>25</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1879-0267</ISSN><JournalIssue CitedMedium="Internet"><Volume>44</Volume><Issue>1</Issue><PubDate><Year>2013</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Injury</Title><ISOAbbreviation>Injury</ISOAbbreviation></Journal><ArticleTitle>Doxycycline sclerodesis as a treatment option for persistent Morel-Lavallée lesions.</ArticleTitle><Pagination><MedlinePgn>66-9</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.injury.2011.11.024</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0020-1383(11)00570-5</ELocationID><Abstract><AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Morel-Lavallée lesion is a rare cause of subcutaneous swelling, caused by post-traumatic shearing of the hypodermis from the underlying fascia. Treatment of such lesions is still not well established.</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To evaluate the results of conservative treatment for these lesions using doxycycline induced sclerodesis followed by elastic compression bandaging.</AbstractText><AbstractText Label="PATIENTS AND METHODS" NlmCategory="METHODS">We treated 16 Morel-Lavallée lesions between May 2005 and December 2008. These lesions developed in 13 male and 3 female patients (mean age 41 years; range 10-74 years) due to various modes of trauma. The lesion involved the thigh region in 13 patients with trochanteric region, gluteal, lower back, and lower abdominal wall being other regions involved. An area of palpable fluctuance was the most consistent examination finding. Treatment was effected by fluid aspiration, doxycycline instillation, and compressive elastic bandaging. Healing was defined as the loss of fluctuation with complete absence of fluid on ultrasonography.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The average duration of the persistence of the lesion was 13 months (range, 6-23 months). Most of the lesions had been aspirated previously multiple number of times, average being 3.44 times (range, 1-6 times). All lesions were aspirated and found to be negative on culture. The mean follow up period was 50.44 months (range, 31-74 months). 11 patients showed complete resolution of fluid collection at 4 weeks with another 4 patients resolving at 8 weeks follow up. The lesion persisted in one patient at 12 weeks due to non-compliance to compressive elastic bandaging which subsequently resolved on repeating the procedure. All the lesions healed without any infections or necrosis. No recurrences were detected during the follow up period. A persistent non-fluctuant contour deformity, decreased skin mobility over the site of lesion, and feeling of tightness were the most common problems faced on long term follow up.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Closed degloving injuries can be managed satisfactorily with doxycycline induced obliteration of the cavity with early healing time without recurrences.</AbstractText><CopyrightInformation>Copyright © 2011 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bansal</LastName><ForeName>Abhishek</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Sports Injury Centre, Safdarjang Hospital, New Delhi 110029, India. drabhishekbansal@ymail.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bhatia</LastName><ForeName>Naval</ForeName><Initials>N</Initials></Author><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Archana</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Singh</LastName><ForeName>Ashwani Kumar</ForeName><Initials>AK</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D023362">Evaluation Studies</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2011</Year><Month>12</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Injury</MedlineTA><NlmUniqueID>0226040</NlmUniqueID><ISSNLinking>0020-1383</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000900">Anti-Bacterial Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>N12000U13O</RegistryNumber><NameOfSubstance UI="D004318">Doxycycline</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000900" MajorTopicYN="N">Anti-Bacterial Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D044963" MajorTopicYN="N">Biopsy, Fine-Needle</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058128" MajorTopicYN="Y">Compression Bandages</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003646" MajorTopicYN="N">Debridement</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004318" MajorTopicYN="N">Doxycycline</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="Y">administration & dosage</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008209" MajorTopicYN="N">Lymphedema</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011859" MajorTopicYN="N">Radiography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017695" MajorTopicYN="N">Soft Tissue Injuries</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="N">diagnostic imaging</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016896" MajorTopicYN="N">Treatment Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014945" MajorTopicYN="N">Wound Healing</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2011</Year><Month>07</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2011</Year><Month>11</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2011</Year><Month>11</Month><Day>26</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2011</Year><Month>12</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2011</Year><Month>12</Month><Day>30</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>5</Month><Day>17</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">22204771</ArticleId><ArticleId IdType="pii">S0020-1383(11)00570-5</ArticleId><ArticleId IdType="doi">10.1016/j.injury.2011.11.024</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Inde</li></country></list><tree><noCountry><name sortKey="Bhatia, Naval" sort="Bhatia, Naval" uniqKey="Bhatia N" first="Naval" last="Bhatia">Naval Bhatia</name><name sortKey="Singh, Archana" sort="Singh, Archana" uniqKey="Singh A" first="Archana" last="Singh">Archana Singh</name><name sortKey="Singh, Ashwani Kumar" sort="Singh, Ashwani Kumar" uniqKey="Singh A" first="Ashwani Kumar" last="Singh">Ashwani Kumar Singh</name></noCountry><country name="Inde"><noRegion><name sortKey="Bansal, Abhishek" sort="Bansal, Abhishek" uniqKey="Bansal A" first="Abhishek" last="Bansal">Abhishek Bansal</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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