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Efficacy of complete decongestive therapy (CDT) on edematous rat limb after lymphadenectomy demonstrated by real time lymphatic fluid tracing.

Identifieur interne : 001B52 ( PubMed/Checkpoint ); précédent : 001B51; suivant : 001B53

Efficacy of complete decongestive therapy (CDT) on edematous rat limb after lymphadenectomy demonstrated by real time lymphatic fluid tracing.

Auteurs : Yukari Takeno [Japon] ; Hiromi Arita ; Etsuko Fujimoto

Source :

RBID : pubmed:23795339

Abstract

Although complete decongestive therapy (CDT) is considered to reduce the volume of lymphedema, there is no concrete evidence to sustain its efficacy. The purpose of the present study was to find new evidence of CDT based on visualizing the changes of lymph fluid accumulating in an edematous limb using indocyanine green (ICG) fluorescent lymphography in real time.Twelve lymphedema rats were divided randomly into two groups. On the first day, ICG was injected into an edematous limb of rats, and no-intervention and CDT was applied to groups 1 and 2, respectively, for two weeks. ICG lymphography and circumferential measurements were done every two days in each two-week observation. The results indicates that a fluorescent flow to the ipsilateral axillary fossa was identified in all rats. In addition, network-like and dermal backflow patterns were observed in the lower legs and thighs. While manual lymph drainage was applied in the CDT group, the flow moved more rapidly through this pathway than that in the no-intervention group. An area of high-intensity fluorescent signals concentrated around the injection sites diminished in the CDT group more than that in the no-intervention-group after two weeks. Circumferential lengths of the edematous limbs were longer than the non-edematous limbs in both groups 1 and 2 on the day of ICG injection. The no-intervention group 1 showed no significance differences during 14 days, whereas the CDT group 2 exhibited very significant differences. These results suggest that CDT has beneficial effects in lymphedema treatment.

DOI: 10.1186/2193-1801-2-225
PubMed: 23795339


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<div type="abstract" xml:lang="en">Although complete decongestive therapy (CDT) is considered to reduce the volume of lymphedema, there is no concrete evidence to sustain its efficacy. The purpose of the present study was to find new evidence of CDT based on visualizing the changes of lymph fluid accumulating in an edematous limb using indocyanine green (ICG) fluorescent lymphography in real time.Twelve lymphedema rats were divided randomly into two groups. On the first day, ICG was injected into an edematous limb of rats, and no-intervention and CDT was applied to groups 1 and 2, respectively, for two weeks. ICG lymphography and circumferential measurements were done every two days in each two-week observation. The results indicates that a fluorescent flow to the ipsilateral axillary fossa was identified in all rats. In addition, network-like and dermal backflow patterns were observed in the lower legs and thighs. While manual lymph drainage was applied in the CDT group, the flow moved more rapidly through this pathway than that in the no-intervention group. An area of high-intensity fluorescent signals concentrated around the injection sites diminished in the CDT group more than that in the no-intervention-group after two weeks. Circumferential lengths of the edematous limbs were longer than the non-edematous limbs in both groups 1 and 2 on the day of ICG injection. The no-intervention group 1 showed no significance differences during 14 days, whereas the CDT group 2 exhibited very significant differences. These results suggest that CDT has beneficial effects in lymphedema treatment.</div>
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<RefSource>Eur J Cancer Care (Engl). 1998 Dec;7(4):255-62</RefSource>
<PMID Version="1">9919113</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Vasc Med. 1998;3(2):145-56</RefSource>
<PMID Version="1">9796078</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Breast Cancer. 2005;12(3):211-5</RefSource>
<PMID Version="1">16110291</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Breast Cancer Res Treat. 2010 Jun;121(2):373-8</RefSource>
<PMID Version="1">20140704</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Ann Plast Surg. 2007 Jun;58(6):652-5</RefSource>
<PMID Version="1">17522489</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>N Engl J Med. 1999 Feb 4;340(5):346-50</RefSource>
<PMID Version="1">9929524</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Eur J Vasc Endovasc Surg. 2008 Aug;36(2):230-6</RefSource>
<PMID Version="1">18534875</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Lymphology. 2009 Jun;42(2):51-60</RefSource>
<PMID Version="1">19725269</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Int J Radiat Oncol Biol Phys. 2007 Mar 1;67(3):841-6</RefSource>
<PMID Version="1">17175115</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Int J Cancer. 2010 Dec 15;127(12):2893-917</RefSource>
<PMID Version="1">21351269</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Palliat Care. 2008 Autumn;24(3):134-43</RefSource>
<PMID Version="1">18942563</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Surg Today. 2011 Feb;41(2):197-202</RefSource>
<PMID Version="1">21264754</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Cancer. 2008 Feb 15;112(4):950-4</RefSource>
<PMID Version="1">18085587</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Cancer J. 2004 Jan-Feb;10(1):42-8; discussion 17-9</RefSource>
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