Serveur d'exploration sur le lymphœdème

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Risk factors associated with breast cancer-related lymphedema in the WHEL Study.

Identifieur interne : 001905 ( PubMed/Checkpoint ); précédent : 001904; suivant : 001906

Risk factors associated with breast cancer-related lymphedema in the WHEL Study.

Auteurs : Sally A. Dominick [États-Unis] ; Lisa Madlensky ; Loki Natarajan ; John P. Pierce

Source :

RBID : pubmed:23212606

Descripteurs français

English descriptors

Abstract

Lymphedema is a significant health problem faced by a large percentage of breast cancer survivors. The Women's Healthy Eating and Living (WHEL) Study has a unique dataset collected after the completion of breast cancer treatment, which allowed a focused analysis of risk factors for breast cancer-related lymphedema.

DOI: 10.1007/s11764-012-0251-9
PubMed: 23212606


Affiliations:


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pubmed:23212606

Le document en format XML

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<div type="abstract" xml:lang="en">Lymphedema is a significant health problem faced by a large percentage of breast cancer survivors. The Women's Healthy Eating and Living (WHEL) Study has a unique dataset collected after the completion of breast cancer treatment, which allowed a focused analysis of risk factors for breast cancer-related lymphedema.</div>
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<ArticleTitle>Risk factors associated with breast cancer-related lymphedema in the WHEL Study.</ArticleTitle>
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<AbstractText Label="INTRODUCTION" NlmCategory="BACKGROUND">Lymphedema is a significant health problem faced by a large percentage of breast cancer survivors. The Women's Healthy Eating and Living (WHEL) Study has a unique dataset collected after the completion of breast cancer treatment, which allowed a focused analysis of risk factors for breast cancer-related lymphedema.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Participant characteristics, treatment modalities, and health behaviors were examined as potential predictors of lymphedema among breast cancer survivors with univariate analyses and multivariate logistic regression.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Lymphedema status was assessed for 83 % of the study cohort (2,431 of the 2,917 WHEL participants). Among these respondents, 692 (28.5 %) women reported yes to either a physician's diagnosis of lymphedema or a question on arm/hand swelling. When compared to other participants, women with lymphedema were diagnosed at a younger age, more likely to have a higher body mass index, had a larger tumor size, had more lymph nodes removed, more likely to have a mastectomy with radiation therapy, and more likely to have chemotherapy. In the final multivariate-adjusted model, body mass index greater than 25 kg/m(2) (p < 0.01), the removal of 11 or more lymph nodes (p < 0.01), and breast cancer surgery plus radiation therapy (p < 0.01) showed a strong independent association with developing breast cancer-related lymphedema.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The results of this study highlight the importance of educating breast cancer survivors about the modifiable risk factors (e.g., body mass index) associated with the development of lymphedema.</AbstractText>
<AbstractText Label="IMPLICATIONS FOR CANCER SURVIVORS" NlmCategory="CONCLUSIONS">Breast cancer survivors at risk for lymphedema may benefit from interventions aimed at achieving or maintaining a healthy body weight.</AbstractText>
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}}

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HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i   -Sk "pubmed:23212606" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd   \
       | NlmPubMed2Wicri -a LymphedemaV1 

Wicri

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