The anti-neoplastic effects of coumarin: an emerging concept.
Identifieur interne : 001844 ( PubMed/Checkpoint ); précédent : 001843; suivant : 001845The anti-neoplastic effects of coumarin: an emerging concept.
Auteurs : Shailendra Kapoor [Oman]Source :
- Cytotechnology [ 0920-9069 ] ; 2013.
Abstract
The recent article by Liu et al. provided for highly interesting reading. Interestingly, recent data suggests that coumarin may exert significant anti-neoplastic effects in a number of systemic malignancies. Coumarin is also of clinical benefit in mammary malignancies. For instance, it attenuates the extent of extremity lymphedema following breast cancer surgery and radiation therapy. In one recent study, an almost 12.5 % decline in the volume of upper extremity lymphedema was noticed. As a result, quality of life is significantly improved. Similar attenuation of tumor growth has been seen in pulmonary malignancies. It mediates these anti-neoplastic effects by attenuating Bcl-2 expression within the tumor cells. On the other hand, Bax expression within the tumor cells is markedly accentuated. These changes have recently been confirmed in A549 cells.
DOI: 10.1007/s10616-013-9538-6
PubMed: 23340967
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:23340967Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The anti-neoplastic effects of coumarin: an emerging concept.</title><author><name sortKey="Kapoor, Shailendra" sort="Kapoor, Shailendra" uniqKey="Kapoor S" first="Shailendra" last="Kapoor">Shailendra Kapoor</name><affiliation wicri:level="1"><nlm:affiliation>, 74 Crossing Place, Mechanicsville, VA, USA, shailendrakapoor@yahoo.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>, 74 Crossing Place, Mechanicsville, VA, USA</wicri:regionArea><wicri:noRegion>USA</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2013">2013</date><idno type="RBID">pubmed:23340967</idno><idno type="pmid">23340967</idno><idno type="doi">10.1007/s10616-013-9538-6</idno><idno type="wicri:Area/PubMed/Corpus">001D43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001D43</idno><idno type="wicri:Area/PubMed/Curation">001D43</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001D43</idno><idno type="wicri:Area/PubMed/Checkpoint">001D43</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001D43</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The anti-neoplastic effects of coumarin: an emerging concept.</title><author><name sortKey="Kapoor, Shailendra" sort="Kapoor, Shailendra" uniqKey="Kapoor S" first="Shailendra" last="Kapoor">Shailendra Kapoor</name><affiliation wicri:level="1"><nlm:affiliation>, 74 Crossing Place, Mechanicsville, VA, USA, shailendrakapoor@yahoo.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>, 74 Crossing Place, Mechanicsville, VA, USA</wicri:regionArea><wicri:noRegion>USA</wicri:noRegion></affiliation></author></analytic><series><title level="j">Cytotechnology</title><idno type="ISSN">0920-9069</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The recent article by Liu et al. provided for highly interesting reading. Interestingly, recent data suggests that coumarin may exert significant anti-neoplastic effects in a number of systemic malignancies. Coumarin is also of clinical benefit in mammary malignancies. For instance, it attenuates the extent of extremity lymphedema following breast cancer surgery and radiation therapy. In one recent study, an almost 12.5 % decline in the volume of upper extremity lymphedema was noticed. As a result, quality of life is significantly improved. Similar attenuation of tumor growth has been seen in pulmonary malignancies. It mediates these anti-neoplastic effects by attenuating Bcl-2 expression within the tumor cells. On the other hand, Bax expression within the tumor cells is markedly accentuated. These changes have recently been confirmed in A549 cells.</div></front></TEI><pubmed><MedlineCitation Status="PubMed-not-MEDLINE" Owner="NLM"><PMID Version="1">23340967</PMID><DateCreated><Year>2013</Year><Month>10</Month><Day>25</Day></DateCreated><DateCompleted><Year>2013</Year><Month>10</Month><Day>25</Day></DateCompleted><DateRevised><Year>2017</Year><Month>02</Month><Day>20</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0920-9069</ISSN><JournalIssue CitedMedium="Print"><Volume>65</Volume><Issue>5</Issue><PubDate><Year>2013</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Cytotechnology</Title><ISOAbbreviation>Cytotechnology</ISOAbbreviation></Journal><ArticleTitle>The anti-neoplastic effects of coumarin: an emerging concept.</ArticleTitle><Pagination><MedlinePgn>787-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s10616-013-9538-6</ELocationID><Abstract><AbstractText>The recent article by Liu et al. provided for highly interesting reading. Interestingly, recent data suggests that coumarin may exert significant anti-neoplastic effects in a number of systemic malignancies. Coumarin is also of clinical benefit in mammary malignancies. For instance, it attenuates the extent of extremity lymphedema following breast cancer surgery and radiation therapy. In one recent study, an almost 12.5 % decline in the volume of upper extremity lymphedema was noticed. As a result, quality of life is significantly improved. Similar attenuation of tumor growth has been seen in pulmonary malignancies. It mediates these anti-neoplastic effects by attenuating Bcl-2 expression within the tumor cells. On the other hand, Bax expression within the tumor cells is markedly accentuated. These changes have recently been confirmed in A549 cells.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kapoor</LastName><ForeName>Shailendra</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>, 74 Crossing Place, Mechanicsville, VA, USA, shailendrakapoor@yahoo.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>01</Month><Day>23</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Cytotechnology</MedlineTA><NlmUniqueID>8807027</NlmUniqueID><ISSNLinking>0920-9069</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Cancer Chemother Pharmacol. 1989;24(1):65-6</RefSource><PMID Version="1">2720893</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cancer Res Clin Oncol. 1994;120 Suppl:S14-6</RefSource><PMID Version="1">8132695</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lymphology. 1999 Mar;32(1):3-10</RefSource><PMID Version="1">10197321</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Cytotechnology. 2013 Aug;65(4):597-608</RefSource><PMID Version="1">23161221</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Anticancer Res. 2012 Oct;32(10):4271-6</RefSource><PMID Version="1">23060547</PMID></CommentsCorrections></CommentsCorrectionsList><OtherID Source="NLM">PMC3967608</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>01</Month><Day>07</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>01</Month><Day>09</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2013</Year><Month>1</Month><Day>24</Day><Hour>6</Hour><Minute>1</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23340967</ArticleId><ArticleId IdType="doi">10.1007/s10616-013-9538-6</ArticleId><ArticleId IdType="pmc">PMC3967608</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Oman</li></country></list><tree><country name="Oman"><noRegion><name sortKey="Kapoor, Shailendra" sort="Kapoor, Shailendra" uniqKey="Kapoor S" first="Shailendra" last="Kapoor">Shailendra Kapoor</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001844 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 001844 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:23340967
|texte= The anti-neoplastic effects of coumarin: an emerging concept.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:23340967" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |