Key concepts in management of vulvar cancer.
Identifieur interne : 001486 ( PubMed/Checkpoint ); précédent : 001485; suivant : 001487Key concepts in management of vulvar cancer.
Auteurs : Susan Zweizig [États-Unis] ; Sharmilee Korets [États-Unis] ; Joanna M. Cain [États-Unis]Source :
- Best practice & research. Clinical obstetrics & gynaecology [ 1532-1932 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- diagnostic : Tumeurs de la vulve.
- étiologie : Tumeurs de la vulve.
- Facteurs de risque, Femelle, Humains, Infections à papillomavirus, Papillomaviridae, Tumeurs de la vulve.
English descriptors
- KwdEn :
- MESH :
- complications : Papillomavirus Infections.
- diagnosis : Vulvar Neoplasms.
- etiology : Vulvar Neoplasms.
- therapy : Vulvar Neoplasms.
- Female, Humans, Papillomaviridae, Risk Factors.
Abstract
Vulvar carcinoma is an uncommon tumor that is seen most often in older women. Subtle symptoms such as pruritus should prompt examination and targeted biopsy in all women as this disease can be successfully treated even in elderly, frail individuals. Vulvar cancer has a bimodal age distribution and is seen in both young and older women with risk factors including human papillomavirus (HPV) infection, smoking, and vulvar skin diseases (i.e., lichen sclerosus). This cancer is staged surgically, with an update in 2009 incorporating prognostic factors. The treatment of vulvar carcinoma has evolved to include more conservative surgical techniques that provide improved cure rates with emphasis on minimizing morbidity. Advanced and metastatic lesions are now treated with chemoradiation which produces substantial cure rates with decreased morbidity. Promising areas of research in vulvar cancer include refinement of sentinel lymph node biopsy, prevention of lymphedema, and preservation of sexual function following treatment.
DOI: 10.1016/j.bpobgyn.2014.07.001
PubMed: 25151473
Affiliations:
Links toward previous steps (curation, corpus...)
Links to Exploration step
pubmed:25151473Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Key concepts in management of vulvar cancer.</title><author><name sortKey="Zweizig, Susan" sort="Zweizig, Susan" uniqKey="Zweizig S" first="Susan" last="Zweizig">Susan Zweizig</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Susan.Zweizig@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Korets, Sharmilee" sort="Korets, Sharmilee" uniqKey="Korets S" first="Sharmilee" last="Korets">Sharmilee Korets</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Sharmilee.Korets@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Cain, Joanna M" sort="Cain, Joanna M" uniqKey="Cain J" first="Joanna M" last="Cain">Joanna M. Cain</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Joanna.Cain@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25151473</idno><idno type="pmid">25151473</idno><idno type="doi">10.1016/j.bpobgyn.2014.07.001</idno><idno type="wicri:Area/PubMed/Corpus">001362</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001362</idno><idno type="wicri:Area/PubMed/Curation">001362</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001362</idno><idno type="wicri:Area/PubMed/Checkpoint">001362</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001362</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Key concepts in management of vulvar cancer.</title><author><name sortKey="Zweizig, Susan" sort="Zweizig, Susan" uniqKey="Zweizig S" first="Susan" last="Zweizig">Susan Zweizig</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Susan.Zweizig@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Korets, Sharmilee" sort="Korets, Sharmilee" uniqKey="Korets S" first="Sharmilee" last="Korets">Sharmilee Korets</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Sharmilee.Korets@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Cain, Joanna M" sort="Cain, Joanna M" uniqKey="Cain J" first="Joanna M" last="Cain">Joanna M. Cain</name><affiliation wicri:level="2"><nlm:affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Joanna.Cain@umassmemorial.org.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author></analytic><series><title level="j">Best practice & research. Clinical obstetrics & gynaecology</title><idno type="eISSN">1532-1932</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Female</term><term>Humans</term><term>Papillomaviridae</term><term>Papillomavirus Infections (complications)</term><term>Risk Factors</term><term>Vulvar Neoplasms (diagnosis)</term><term>Vulvar Neoplasms (etiology)</term><term>Vulvar Neoplasms (therapy)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Infections à papillomavirus ()</term><term>Papillomaviridae</term><term>Tumeurs de la vulve ()</term><term>Tumeurs de la vulve (diagnostic)</term><term>Tumeurs de la vulve (étiologie)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Papillomavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Tumeurs de la vulve</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Vulvar Neoplasms</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Tumeurs de la vulve</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Female</term><term>Humans</term><term>Papillomaviridae</term><term>Risk Factors</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Facteurs de risque</term><term>Femelle</term><term>Humains</term><term>Infections à papillomavirus</term><term>Papillomaviridae</term><term>Tumeurs de la vulve</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Vulvar carcinoma is an uncommon tumor that is seen most often in older women. Subtle symptoms such as pruritus should prompt examination and targeted biopsy in all women as this disease can be successfully treated even in elderly, frail individuals. Vulvar cancer has a bimodal age distribution and is seen in both young and older women with risk factors including human papillomavirus (HPV) infection, smoking, and vulvar skin diseases (i.e., lichen sclerosus). This cancer is staged surgically, with an update in 2009 incorporating prognostic factors. The treatment of vulvar carcinoma has evolved to include more conservative surgical techniques that provide improved cure rates with emphasis on minimizing morbidity. Advanced and metastatic lesions are now treated with chemoradiation which produces substantial cure rates with decreased morbidity. Promising areas of research in vulvar cancer include refinement of sentinel lymph node biopsy, prevention of lymphedema, and preservation of sexual function following treatment.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25151473</PMID><DateCreated><Year>2014</Year><Month>12</Month><Day>02</Day></DateCreated><DateCompleted><Year>2015</Year><Month>08</Month><Day>13</Day></DateCompleted><DateRevised><Year>2014</Year><Month>12</Month><Day>02</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1532-1932</ISSN><JournalIssue CitedMedium="Internet"><Volume>28</Volume><Issue>7</Issue><PubDate><Year>2014</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Best practice & research. Clinical obstetrics & gynaecology</Title><ISOAbbreviation>Best Pract Res Clin Obstet Gynaecol</ISOAbbreviation></Journal><ArticleTitle>Key concepts in management of vulvar cancer.</ArticleTitle><Pagination><MedlinePgn>959-66</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.bpobgyn.2014.07.001</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S1521-6934(14)00125-4</ELocationID><Abstract><AbstractText>Vulvar carcinoma is an uncommon tumor that is seen most often in older women. Subtle symptoms such as pruritus should prompt examination and targeted biopsy in all women as this disease can be successfully treated even in elderly, frail individuals. Vulvar cancer has a bimodal age distribution and is seen in both young and older women with risk factors including human papillomavirus (HPV) infection, smoking, and vulvar skin diseases (i.e., lichen sclerosus). This cancer is staged surgically, with an update in 2009 incorporating prognostic factors. The treatment of vulvar carcinoma has evolved to include more conservative surgical techniques that provide improved cure rates with emphasis on minimizing morbidity. Advanced and metastatic lesions are now treated with chemoradiation which produces substantial cure rates with decreased morbidity. Promising areas of research in vulvar cancer include refinement of sentinel lymph node biopsy, prevention of lymphedema, and preservation of sexual function following treatment.</AbstractText><CopyrightInformation>Copyright © 2014 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zweizig</LastName><ForeName>Susan</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Susan.Zweizig@umassmemorial.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Korets</LastName><ForeName>Sharmilee</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Sharmilee.Korets@umassmemorial.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cain</LastName><ForeName>Joanna M</ForeName><Initials>JM</Initials><AffiliationInfo><Affiliation>University of Massachusetts Medical School, 119 Belmont Street, Worcester, MA 01605, USA. Electronic address: Joanna.Cain@umassmemorial.org.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2014</Year><Month>07</Month><Day>17</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Best Pract Res Clin Obstet Gynaecol</MedlineTA><NlmUniqueID>101121582</NlmUniqueID><ISSNLinking>1521-6934</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D027383" MajorTopicYN="N">Papillomaviridae</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D030361" MajorTopicYN="N">Papillomavirus Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D014846" MajorTopicYN="N">Vulvar Neoplasms</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">HPV infection</Keyword><Keyword MajorTopicYN="N">chemoradiation</Keyword><Keyword MajorTopicYN="N">sentinel node</Keyword><Keyword MajorTopicYN="N">vulvar carcinoma</Keyword><Keyword MajorTopicYN="N">vulvar intraepithelial neoplasia</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>09</Month><Day>06</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2014</Year><Month>07</Month><Day>10</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2014</Year><Month>8</Month><Day>25</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2014</Year><Month>8</Month><Day>26</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>8</Month><Day>14</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">25151473</ArticleId><ArticleId IdType="pii">S1521-6934(14)00125-4</ArticleId><ArticleId IdType="doi">10.1016/j.bpobgyn.2014.07.001</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>États-Unis</li></country><region><li>Massachusetts</li></region></list><tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Zweizig, Susan" sort="Zweizig, Susan" uniqKey="Zweizig S" first="Susan" last="Zweizig">Susan Zweizig</name></region><name sortKey="Cain, Joanna M" sort="Cain, Joanna M" uniqKey="Cain J" first="Joanna M" last="Cain">Joanna M. Cain</name><name sortKey="Korets, Sharmilee" sort="Korets, Sharmilee" uniqKey="Korets S" first="Sharmilee" last="Korets">Sharmilee Korets</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/PubMed/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001486 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd -nk 001486 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= PubMed
|étape= Checkpoint
|type= RBID
|clé= pubmed:25151473
|texte= Key concepts in management of vulvar cancer.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Checkpoint/RBID.i -Sk "pubmed:25151473" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |